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  1. 67761

    Exploring the differential responses of ecosystem services to urbanization: A perspective from the metropolitan area as a whole and internal service bundles by Xianxin Meng, Zhenxiang Ling, Yingbiao Chen, Xiaohao Zheng, Xianghua Shi, Junyu Kuang, Wentao Chen, Yifan Yang, Zhifeng Wu, Zihao Zheng

    Published 2025-07-01
    “…Rapid economic growth and urban expansion have significantly disrupted the original structure and functions of ecosystems. Achieving a balanced development between the economy and ecology has become a critical challenge. …”
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  2. 67762

    Honeybees fed D-galactose exhibit aging signs with changes in gut microbiota and metabolism by Guanzhou Zhou, Jiabin Hu, Mengqi Xu, Yiyuan Li, Ruqi Chang, Jiaqi Zeng, Wanyue Dan, Lihua Peng, Zikai Wang, Gang Sun, Fei Pan, Yunsheng Yang

    Published 2025-04-01
    “…This study explored the effect of D-galactose, a common aging inducer, on honeybees and investigated the associated effects and mechanisms, with particular focus on the potential protective role of sodium butyrate. …”
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  3. 67763
  4. 67764

    Study protocol: a randomized controlled clinical trial on the use of electroacupuncture for postoperative abdominal distension following laparoscopic cholecystectomy by Qi Kong, Qi Kong, Qi Kong, Wei Wang, Xin-Yi Chen, Li-Ming Chen, Long-Kai Sun, Long-Kai Sun, Shao-Hua Qu, Wen-Tao Wu, Jia-Hua Yang, Yu Shu, Sen Li, Pei-Hao Yin, Pei-Hao Yin, Pei-Hao Yin, Wei Li, Wei Li

    Published 2025-08-01
    “…Acupuncture is one of the distinct treatment methods in TCM (Traditional Chinese Medicine), characterized by its simplicity, practicability, and minimal side effects. Previous studies have confirmed the effectiveness of acupuncture intervention for gastrointestinal functionality.MethodThis study is a randomized, single-blind, controlled pilot clinical trial. …”
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    Article
  5. 67765

    Nucleotide receptor P2X7/STAT6 pathway regulates macrophage M2 polarization and its application in CAR-T immunotherapy by Qin Si, Lu Yang, Jie Liu, Hui Liu, Ruifang Bu, Na Cui

    Published 2025-01-01
    “…Furthermore, M2 macrophage suppresses the toxic effect of CAR-T cells on OC cells, while silencing the P2X7 receptor nullifies the immunosuppressive effect of M2 macrophages on CAR-T cells. …”
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    Article
  6. 67766

    Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue by Carol Costa Encarnação, Carolinne Souza Amorim, Victor Aguiar Franco, Luiz Gabriel Xavier Botelho, Ronan Christian Machado dos Santos, Isadora Ramos-Andrade, Luiz Guilherme Kraemer-Aguiar, Christina Barja-Fidalgo, João Alfredo Moraes, Mariana Renovato-Martins

    Published 2025-05-01
    “…In this study, we investigated the effects of leptin within extracellular vesicles (EVs) secreted by obese adipose tissue on the functional properties and metabolism of MDA-MB-231 breast cancer cells, a model for triple-negative breast cancer (TNBC).MethodMDA-MB-231 cells were treated with EVs derived from the subcutaneous adipose tissue of eutrophic (EUT EVs) and obese (OB EVs) individuals.ResultsOur findings revealed that OB EVs induced significant phosphorylation of STAT3, a key signaling molecule in cancer progression, and promoted increased cell migration, dependent on fatty acid oxidation (FAO). …”
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  7. 67767

    Integrated Genome-Wide Analysis of Gene Expression and DNA Copy Number Variations Highlights Stem Cell-Related Pathways in Small Cell Esophageal Carcinoma by Di Liu, Xinyan Xu, Junmiao Wen, Liyi Xie, Junhua Zhang, Yuxin Shen, Guoliang Jiang, Jiayan Chen, Min Fan

    Published 2018-01-01
    “…These overlapped genes were subjected to the functional annotation using DAVID 6.8. In order to elucidate the effect of CNV on mRNA expression, we integrated the genome-wide copy number data and gene expression in 3 paired samples. …”
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  8. 67768
  9. 67769

    Performance Study of Non-Contact Membrane Distillation Engineering Prototype for Treatment of Radioactive Wastewater by Bao-lin WANG, De-tao XIAO, Zheng-zhong HE, Xing-feng YANG, Cheng-lin LI

    Published 2025-04-01
    “…This adjustable treatment capacity allows operators to calibrate the processing rate in real time, aligning the system’s functionality with varying demands and expanding its applicability across diverse use cases. …”
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    Article
  10. 67770

    Study on correlation between coal spontaneous combustion characteristic temperature and physical and chemical characteristic parameters by Cheng WAN, Binbin ZHANG, Dailin LI, Yin LIU, Yanfeng CHEN, Jun GUO, Yunfei WU

    Published 2025-06-01
    “…The hydroxyl group is also continuously consumed due to other functional groups. The reaction continues to generate. …”
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  11. 67771

    Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial by Petr Burkon, Iveta Selingerova, Miroslav Vrzal, Milos Holanek, Oldrich Coufal, Katerina Polachova, Vera Andraskova, Sachin R. Jhawar, Pavel Slampa, Tomas Kazda, Marek Slavik

    Published 2025-01-01
    “…Patients in the APBI arm reported more favorable global health status at M6 (p = 0.055). Other functional scales showed a decrease in the WBI arm at M0 (p = 0.027 for physical functioning). …”
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  12. 67772

    DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy by Jinjin Ma, Xinyu Wang, Dalei Sun, Jiali Chen, Linyi Zhou, Kaiao Zou, Xinxin Ni, Hongting Jin, Jun Lin

    Published 2025-07-01
    “…Furthermore, inhibition of mitophagy in M1 macrophages partially attenuated the M2 polarization effect and phagocytosis induced by DPSCs. Conclusion DPSCs significantly mitigate synovitis in TMJOA rats by enhancing M2 polarization and efferocytic functions of macrophages. …”
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  13. 67773

    Autonomic support of central hemodynamics and physical working capacity in female swimmers and runners in a one-year training cycle by Ye. L. Mykhaliuk, V. V. Syvolap, Ye. Yu. Horokhovskyi

    Published 2022-02-01
    “…Physical working capacity (PWC) was measured using a submaximal PWC170 test. The functional state index (FSI) was calculated according to the formula that we had proposed and patented. …”
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  14. 67774

    Synthesis, physical and chemical properties, antihypoxic activity of some 5-[((5-(adamantane-1-yl)-4-R-4H-1,2,4-triazole-3-yl)thio)methyl]-N-R1-1,3,4-thiadiazole-2-amines and 5-[((... by V. M. Odyntsova, Ye. G. Knysh, O. I. Panasenko

    Published 2018-03-01
    “…Today, an increase of natural and technogenic situations leads to the disorders of the central nervous system, functional-metabolic processes, vascular diseases, in particular, acute cerebral blood flow disorders. …”
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    Article
  15. 67775

    POLITICAL CORRECTNESS IN POLITICAL DISCOURSE: THEORY OF IDEOLOGICAL ASPECT by Yuliia G. Karachun, Nataliia V. Davydenko

    Published 2023-12-01
    “…The article aims to highlight the ideological aspect of functioning politically correct vocabulary in today’s political discourse. …”
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  16. 67776

    THE FEATURES OF THE FACE SKIN CONSTRUCTION THAT INFLUENCE ON THE FORMATION OF CICATRICAL TISSUES DURING SUGICAL INTERVENTIONS by K.P. Lokes, D.S. Avetikov, S.O. Stavitsky, O.O. Rozkolupa, N.S. Lutsenko

    Published 2019-12-01
    “…The analysis of domestic and foreign literary sources was devoted to the peculiarities of the structure of the skin of the head and neck and the optimization of the skin incisions of this localization. Functional features of human skin depend on the mechanical properties of the dermis, which provides elasticity and resistance to stretching. …”
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  17. 67777

    TCF12 enhances angiogenesis and affects sorafenib response in liver cancer via HIF-1α interaction by Yuanbin Chen, Xiaolong Wang, Jin Chen, Min Dai, Xinyue Zhang, Jie Yin, Xiao He

    Published 2025-04-01
    “…Notably, overexpression of HIF-1α reversed these effects, and co-immunoprecipitation experiments confirmed a direct interaction between TCF12 and HIF-1α. …”
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  18. 67778

    STUDY OF THE CELLULAR COMPONENT OF IMMUNE SYSTEM IN CASES OF TRAUMATIC MANDIBULAR FRACTURE IN PATIENTS OF DIFFERENT PSYCHOSOMATIC PERSONALITY TYPES by Ya.P. Nahirniy, V. L. Fesyk

    Published 2018-03-01
    “…This influence occurs due to different degree of the effect of psyche on immune system that is crucial in purulent complications development. …”
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    Article
  19. 67779

    Cigarette smoke modulates methylation levels of LEF1-AS1 and impedes its expression: An experimental study by Bader O. Almutairi, Ahmed Rady, Bashayer S. Aljuhani, Mikhlid H. Almutairi

    Published 2025-05-01
    “…The expression analysis of LEF1-AS1 was performed using the GTEx (Genotype-Tissue Expression) database, including an assessment of its expression in various cancers such as lung and brain cancers. The functional analysis of the LEF1-AS1 gene was conducted across multiple tissues using data from the GENT2 databases, along with meta-survival and functional enrichment analysis. …”
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    Article
  20. 67780

    Integrative analysis of T cell-mediated tumor killing-related genes reveals KIF11 as a novel therapeutic target in esophageal squamous cell carcinoma by Xinxin Cheng, Huihui Zhao, Zhangwang Li, Liping Yan, Qingjie Min, Qingnan Wu, Qimin Zhan

    Published 2025-02-01
    “…Moreover, we performed functional experiments on KIF11, which ranked as the most significant prognostic risk gene among the 8 TTK-related genes. …”
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    Article