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67761
Exploring the differential responses of ecosystem services to urbanization: A perspective from the metropolitan area as a whole and internal service bundles
Published 2025-07-01“…Rapid economic growth and urban expansion have significantly disrupted the original structure and functions of ecosystems. Achieving a balanced development between the economy and ecology has become a critical challenge. …”
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67762
Honeybees fed D-galactose exhibit aging signs with changes in gut microbiota and metabolism
Published 2025-04-01“…This study explored the effect of D-galactose, a common aging inducer, on honeybees and investigated the associated effects and mechanisms, with particular focus on the potential protective role of sodium butyrate. …”
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67763
The ReHand-BCI trial: a randomized controlled trial of a brain-computer interface for upper extremity stroke neurorehabilitation
Published 2025-06-01“…Therefore, the study brings light into the neuroplasticity effects of a closed-loop BCI-based neurorehabilitation intervention in stroke.Clinical trial registrationhttps://clinicaltrials.gov/, identifier NCT04724824.…”
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67764
Study protocol: a randomized controlled clinical trial on the use of electroacupuncture for postoperative abdominal distension following laparoscopic cholecystectomy
Published 2025-08-01“…Acupuncture is one of the distinct treatment methods in TCM (Traditional Chinese Medicine), characterized by its simplicity, practicability, and minimal side effects. Previous studies have confirmed the effectiveness of acupuncture intervention for gastrointestinal functionality.MethodThis study is a randomized, single-blind, controlled pilot clinical trial. …”
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67765
Nucleotide receptor P2X7/STAT6 pathway regulates macrophage M2 polarization and its application in CAR-T immunotherapy
Published 2025-01-01“…Furthermore, M2 macrophage suppresses the toxic effect of CAR-T cells on OC cells, while silencing the P2X7 receptor nullifies the immunosuppressive effect of M2 macrophages on CAR-T cells. …”
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67766
Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue
Published 2025-05-01“…In this study, we investigated the effects of leptin within extracellular vesicles (EVs) secreted by obese adipose tissue on the functional properties and metabolism of MDA-MB-231 breast cancer cells, a model for triple-negative breast cancer (TNBC).MethodMDA-MB-231 cells were treated with EVs derived from the subcutaneous adipose tissue of eutrophic (EUT EVs) and obese (OB EVs) individuals.ResultsOur findings revealed that OB EVs induced significant phosphorylation of STAT3, a key signaling molecule in cancer progression, and promoted increased cell migration, dependent on fatty acid oxidation (FAO). …”
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67767
Integrated Genome-Wide Analysis of Gene Expression and DNA Copy Number Variations Highlights Stem Cell-Related Pathways in Small Cell Esophageal Carcinoma
Published 2018-01-01“…These overlapped genes were subjected to the functional annotation using DAVID 6.8. In order to elucidate the effect of CNV on mRNA expression, we integrated the genome-wide copy number data and gene expression in 3 paired samples. …”
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67768
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67769
Performance Study of Non-Contact Membrane Distillation Engineering Prototype for Treatment of Radioactive Wastewater
Published 2025-04-01“…This adjustable treatment capacity allows operators to calibrate the processing rate in real time, aligning the system’s functionality with varying demands and expanding its applicability across diverse use cases. …”
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67770
Study on correlation between coal spontaneous combustion characteristic temperature and physical and chemical characteristic parameters
Published 2025-06-01“…The hydroxyl group is also continuously consumed due to other functional groups. The reaction continues to generate. …”
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67771
Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial
Published 2025-01-01“…Patients in the APBI arm reported more favorable global health status at M6 (p = 0.055). Other functional scales showed a decrease in the WBI arm at M0 (p = 0.027 for physical functioning). …”
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67772
DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy
Published 2025-07-01“…Furthermore, inhibition of mitophagy in M1 macrophages partially attenuated the M2 polarization effect and phagocytosis induced by DPSCs. Conclusion DPSCs significantly mitigate synovitis in TMJOA rats by enhancing M2 polarization and efferocytic functions of macrophages. …”
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67773
Autonomic support of central hemodynamics and physical working capacity in female swimmers and runners in a one-year training cycle
Published 2022-02-01“…Physical working capacity (PWC) was measured using a submaximal PWC170 test. The functional state index (FSI) was calculated according to the formula that we had proposed and patented. …”
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67774
Synthesis, physical and chemical properties, antihypoxic activity of some 5-[((5-(adamantane-1-yl)-4-R-4H-1,2,4-triazole-3-yl)thio)methyl]-N-R1-1,3,4-thiadiazole-2-amines and 5-[((...
Published 2018-03-01“…Today, an increase of natural and technogenic situations leads to the disorders of the central nervous system, functional-metabolic processes, vascular diseases, in particular, acute cerebral blood flow disorders. …”
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67775
POLITICAL CORRECTNESS IN POLITICAL DISCOURSE: THEORY OF IDEOLOGICAL ASPECT
Published 2023-12-01“…The article aims to highlight the ideological aspect of functioning politically correct vocabulary in today’s political discourse. …”
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67776
THE FEATURES OF THE FACE SKIN CONSTRUCTION THAT INFLUENCE ON THE FORMATION OF CICATRICAL TISSUES DURING SUGICAL INTERVENTIONS
Published 2019-12-01“…The analysis of domestic and foreign literary sources was devoted to the peculiarities of the structure of the skin of the head and neck and the optimization of the skin incisions of this localization. Functional features of human skin depend on the mechanical properties of the dermis, which provides elasticity and resistance to stretching. …”
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67777
TCF12 enhances angiogenesis and affects sorafenib response in liver cancer via HIF-1α interaction
Published 2025-04-01“…Notably, overexpression of HIF-1α reversed these effects, and co-immunoprecipitation experiments confirmed a direct interaction between TCF12 and HIF-1α. …”
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67778
STUDY OF THE CELLULAR COMPONENT OF IMMUNE SYSTEM IN CASES OF TRAUMATIC MANDIBULAR FRACTURE IN PATIENTS OF DIFFERENT PSYCHOSOMATIC PERSONALITY TYPES
Published 2018-03-01“…This influence occurs due to different degree of the effect of psyche on immune system that is crucial in purulent complications development. …”
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67779
Cigarette smoke modulates methylation levels of LEF1-AS1 and impedes its expression: An experimental study
Published 2025-05-01“…The expression analysis of LEF1-AS1 was performed using the GTEx (Genotype-Tissue Expression) database, including an assessment of its expression in various cancers such as lung and brain cancers. The functional analysis of the LEF1-AS1 gene was conducted across multiple tissues using data from the GENT2 databases, along with meta-survival and functional enrichment analysis. …”
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67780
Integrative analysis of T cell-mediated tumor killing-related genes reveals KIF11 as a novel therapeutic target in esophageal squamous cell carcinoma
Published 2025-02-01“…Moreover, we performed functional experiments on KIF11, which ranked as the most significant prognostic risk gene among the 8 TTK-related genes. …”
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