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67701
Preparation and characterization of a novel walnut peptide–calcium chelate and its role in promoting calcium absorption in calcium-deficient mice
Published 2025-08-01“…Overall, these findings suggest that WP-Ca shows great potential in the development of new and highly efficient calcium supplements for osteoporosis prevention, nutritional fortification for special populations, and innovation in functional foods.…”
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67702
Thrombotic event prevention in patients with post-infarction chronic heart failure, as а part of complex therapy including various classes of beta -adrenoblockers
Published 2008-12-01“…To compare carvedilol and metoprolol tartrate effects on hemostasis in patients with post-infarction chronic heart failure (CHF), receiving complex therapy. …”
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67703
Critical Role of Extracellular Vesicles in Diffuse Large B-Cell Lymphoma; Pathogenesis, Potential Biomarkers, and Targeted Therapy—A Narrative Review
Published 2024-12-01“…We summarize and discuss the biological functions of EVs in DLBCL and their effects on the tumor microenvironment, highlighting their influence on DLBCL pathobiology, immune evasion, angiogenesis, and drug resistance. …”
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67704
Sequentially assembled co-delivery nanoplatform of SIRT1 protein and SOX9-expressing plasmid for multipronged therapy of intervertebral disc degeneration
Published 2025-05-01“…Then, it was sequentially assembled with SOX9-expressing plasmid, an essential transcription factor to promote extracellular matrix (ECM) biosynthesis, onto a phenylboronic acid-functionalized G5-dendrimer to construct a multifunctional nanoplatform for IVDD therapy. …”
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67705
Thermal tipping points in mediterranean mussel adhesion: molecular mechanisms and mechanical consequences of heatwave on byssus production in Mytilus galloprovincialis
Published 2025-07-01“…We demonstrated that 30 days exposure at 28 °C, alters molecular and functional properties of mussel foot. Results revealed severe downregulation in the synthesis of the proximal, distal and non-gradient pre-collagen byssus components. …”
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67706
The immunopeptidome of colon cancer cells treated with topoisomerase inhibiting drug reveals differential as well as common endogenous protein sampling and display of MHC I-associa...
Published 2025-12-01“…Overall, we present evidence for treatment-inducible differential display of peptides, some of which may affect interactions and functions of immune cells. Given the multitude of factors that modulate the effects of increased MHC I expression and associated peptides, further studies are needed to elucidate the pathophysiological implications of these changes.…”
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67707
Research on Robot Cleaning Path Planning of Vertical Mixing Paddle Surface
Published 2025-06-01“…Extensive experimental results validate the effectiveness of the proposed method in robotic cleaning path planning.…”
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67708
DeFi risk assessment: MakerDAO loan portfolio case
Published 2025-06-01“…Through numerical experiments using artificial and real data, we evaluate the model's effectiveness in assessing risk within the loan portfolio. …”
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67709
A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide
Published 2015-02-01“…Abstract Understanding the functions of multi‐cellular organs in terms of the molecular networks within each cell is an important step in the quest to predict phenotype from genotype. …”
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67710
Impact of the NK Cell Receptor LIR-1 (ILT-2/CD85j/LILRB1) on Cytotoxicity against Multiple Myeloma
Published 2012-01-01“…To our knowledge, this work provides the first investigation of the inhibitory capability of LIR-1 in NK-92-mediated cytotoxicity against MM and the first functional evaluation of LIR-1 on MM and LBCL.…”
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67711
Positive Association between TGFB1 Gene and Susceptibility to Idiopathic Scoliosis in Bulgarian Population
Published 2018-01-01“…The primary goal of the current case-control study is to examine the association between the TGFB1 (-509C/T) functional polymorphic variant and genetic predisposition to IS in the Bulgarian population and the genotype-phenotype correlations in distinct case-control subgroups based on age at onset, family history, and gender. …”
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67712
Purification, characterization and hypoglycemic activity of glycoproteins obtained from pea (Pisum sativum L.)
Published 2021-05-01“…These results indicated that PGP2 has the potential to be developed into a functional food or natural medicine for the treatment of type 2 diabetes mellitus.…”
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67713
Metformin Inhibits Cell Motility and Proliferation of Triple-Negative Breast Cancer Cells by Blocking HMGB1/RAGE Signaling
Published 2025-04-01“…Metformin, a well-established antidiabetic drug, directly interacts with HMGB1, inhibiting its pro-inflammatory functions. This study investigates metformin’s effects on the HMGB1/RAGE signaling pathway in triple-negative breast cancer (TNBC) cells. …”
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67714
Free-caged rearing modes regulate chicken intestinal metabolism by influencing gut microbial homeostasis
Published 2025-01-01“…Linear discriminant analysis Effect Size (LefSe) highlighted five key microorganisms, Gemmiger formicilis, Bacteria unclassified, Bacteroides sp. …”
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67715
Diagnosis and treatment of periprosthetic infection after hip replacement (a review)
Published 2023-01-01“…At the same time, in addition to the threat of generalization of the infectious process, there are functional disorders in the joint area and a general deterioration in the quality of life of the patient. …”
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67716
Detecting Subtle Cyberattacks on Adaptive Cruise Control Vehicles: A Machine Learning Approach
Published 2025-01-01“…With the emergence of vehicles featuring advanced driver-assistance systems like adaptive cruise control (ACC) and additional automated driving functionalities, there has arisen a heightened potential for cyberattacks targeting these automated vehicles (AVs). …”
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67717
Novel Spectroscopic Studies of the Interaction of Three Different Types of Iron Oxide Nanoparticles with Albumin
Published 2024-11-01“…It provides crucial insights into the functional perturbations of albumin binding capacity and the effects of IONPs on the stability and structural modifications of plasma carrier proteins.…”
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67718
Development of an integrated testing and calibration approach for fused filament fabrication of polylactic acid
Published 2025-07-01“…This new test artefact incorporates all-in-one calibration functions, including defect identification, measurement, evaluation, and compensation. …”
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67719
Proline-2′-deoxymugineic acid, a phytosiderophore analog, drives beneficial rhizobacterial community formation to promote peanut micronutrition
Published 2025-03-01“…To address this gap, the DMA analog proline-2′-deoxymugineic (PDMA) was used to evaluate its positive effect on peanut rhizobacterial communities and network structure. …”
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67720
A Biomimetic Flexible Sliding Suction Cup Suitable for Curved Surfaces
Published 2025-02-01“…The sliding suction robots designed for wall-climbing functions could have accuracy defects due to suction cup sealing, friction interference, and surface adaptability. …”
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