Insights into the Biological Activity and Bio‐Interaction Properties of Nanoscale Imine‐Based 2D and 3D Covalent Organic Frameworks by Hao Ye, Carlos Franco, Mostafa A. Aboouf, Markus Thiersch, Semih Sevim, Joaquin Llacer‐Wintle, Andrea Veciana, Gemma Llauradó‐Capdevila, Kaiyuan Wang, Xiang‐Zhong Chen, Qiao Tang, Roc Matheu, Pedro D. Wendel‐Garcia, Pedro A. Sánchez‐Murcia, Bradley J. Nelson, Cong Luo, Josep Puigmartí‐Luis, Salvador Pané

“…Their customizable functionalities and tunable pore structures make them valuable for various biomedical applications such as biosensing, bioimaging, antimicrobial activity, and targeted drug delivery. …”
Get full text

Atomic‐Scale Mechanisms of Nucleation and Stabilization in CuCrO2 and CuFeO2 Delafossite Thin Films on Al2O3 by Anna Scheid, Qi Song, Stephanie Ribet, Colin Ophus, Y. Eren Suyolcu, Darrell G. Schlom, Tobias Heil, Peter A. van Aken

“…The integration of these properties into functional devices requires the successful epitaxial growth of delafossites as thin films on appropriate substrates. …”
Get full text

Shikonin as a therapeutic agent in renal cell carcinoma: insights from TEK-related causal association with glaucoma by Ruyue Jia, Ruyue Jia, Yiran Liang, Benkui Zou, Xiangzhi Li, Tao Chen, Chao Zhang, Jiasheng Bian, Renbo Guo

“…Molecular docking and functional assays evaluated shikonin's effects on TEK and AKT/mTOR signaling.ResultsMR revealed a significant causal relationship between glaucoma and RCC. …”
Get full text

Circular RNA circDCUN1D4 suppresses hepatocellular carcinoma development via targeting the miR-590-5p/ TIMP3 axis by Hongyu Li, Bing Su, Yan Jiang, Boyang Zhang, Rulong Du, Can Song, Bin Hou, Kun Xu, Lida Wu, Yuchun Gu

“…In this study, we investigated the functional role of circular RNA circDCUN1D4 in HCC progression and its potential therapeutic implications. …”
Get full text

Gene2role: a role-based gene embedding method for comparative analysis of signed gene regulatory networks by Xin Zeng, Shu Liu, Bowen Liu, Weihang Zhang, Wanzhe Xu, Fujio Toriumi, Kenta Nakai

“…Initially, we demonstrated the effectiveness of Gene2role in capturing the intricate topological nuances of genes using GRNs inferred from four distinct data sources. …”
Get full text

A role of pigment epithelium-derived factor in zinc-mediated mechanism of neurodegeneration in glaucoma by Dmitry V. Chistyakov, Anatolii S. Belousov, Marina P. Shevelyova, Elena N. Iomdina, Viktoriia E. Baksheeva, Natalia G. Shebardina, Anastasia M. Moysenovich, Timofey K. Bulgakov, Sergey Yu. Petrov, Mikhail L. Shishkin, Sanchay S. Tulush, Veronika V. Tiulina, Ekaterina I. Pogodina, Olga S. Gancharova, Olga M. Filippova, Alexey V. Baldin, Sergey V. Goriainov, Arina I. Nikolskaya, Arthur O. Zalevsky, Andrei A. Deviatkin, Alisa A. Vologzhannikova, Neonila V. Gorokhovets, Ekaterina A. Litus, Sergey V. Komarov, François Devred, Marina G. Sergeeva, Alexey V. Mishin, Sergey S. Bukhdruker, Lijie Wu, Evandro A. Araujo, Andrey A. Zamyatnin, Ivan I. Senin, Dmitry V. Zinchenko, Philipp O. Tsvetkov, Valentin I. Borshchevskiy, Sergei E. Permyakov, Evgeni Yu. Zernii

“…Notably, PEDF secretion is enhanced in both glaucoma and retinal cell models in response to zinc stress; however, zinc binding negatively affects axogenic, differentiative and prosurvival functions of PEDF by suppressing its ability to activate receptor PEDF-R/PNPLA2. …”
Get full text

Motion based ex vivo (MOTEX) culture of breast tumor slices sustains microenvironment composition by Zofia M. Komar, Mieke Bavelaar, Ellen Kageler, Nicole S. Verkaik, Mandy M. van Rosmalen, Carolien H.M. van Deurzen, Michael A. den Bakker, Roland Kanaar, Adriaan B Houtsmuller, Thierry P.P. van den Bosch, Agnes Jager, Dik C. van Gent

“…Personalization of chemotherapy or immunotherapy responses is particularly challenging, as molecular markers do not appear to be sufficiently predictive for therapy response. Functional assays for therapy selection may be the solution for this dilemma. …”
Get full text

Tomato-Nerf: Advancing Tomato Model Reconstruction With Improved Neural Radiance Fields by Xiajun Zheng, Xinyi AI, Hao Qin, Jiacheng Rong, Zhiqin Zhang, Yan Yang, Ting Yuan, Wei Li

“…The proposal sampler targets key regions for rendering, and customized loss functions are designed to optimize specific tasks. …”
Get full text

An Integrated Energy Management Strategy for Efficient Power Flow in EV On-Board Chargers with V2G Capability by Diouri Anas, Khafallah Mohamed, Hassoune Abdelilah, Meskini Mohammed Amine

“…In response, this paper presents a novel energy management strategy tailored for Battery Electric Vehicle (BEV) chargers that integrates both Vehicle-to- Grid (V2G) and Grid-to-Vehicle (G2V) functionalities using Dual Active Bridge (DAB) bidirectional converters within On-Board Chargers (OBCs). …”
Get full text

Physicochemical, morphological, and rheological properties of cellulose nanofibrils produced via ultra-high-pressure homogenization by Lingxin You, Benoît Marcolini, Jérôme Bour, Patrick Grysan, Yves Fleming, Peter Fischer, Christos Soukoulis

“…In conclusion, UHPH is an efficient method to induce the nanofibrillation of cellulose, and improve its techno-functionality.…”
Get full text

YY1-induced Long non-coding RNA HOXA11-AS activates oxidative stress and inflammation by epigenetic modification of Nrf2 pathway to promote keloid formation by Jun Jin, Kai Wang, Chenxi Lu, Chenghao Yao, Feng Xie

“…Its overexpression had the opposite effect, which was reversed by Nrf2 pathway inhibition. …”
Get full text

The role of extracellular vesicles in the diagnosis of glioblastoma progression by A. I. Ryabova, V. A. Novikov, N. V. Yunusova, A. A. Ponomareva, L. V. Spirina, O. V. Gribova

“…Current treatment of tumor recurrence allows to increase patient survival, improve functional outcome and decrease caregivers» load. The standard method of recurrence diagnosis is neuroimaging which at early stages cannot distinguish between tumor recurrence and post-radiation changes. …”
Get full text

SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells by Weiwei Tao, Aili Zhang, Kui Zhai, Zhi Huang, Haidong Huang, Wenchao Zhou, Qian Huang, Xiaoguang Fang, Briana C Prager, Xiuxing Wang, Qiulian Wu, Andrew E Sloan, Manmeet S Ahluwalia, Justin D Lathia, Jennifer S Yu, Jeremy N Rich, Shideng Bao

“…Abstract Nuclear matrix‐associated proteins (NMPs) play critical roles in regulating chromatin organization and gene transcription by binding to the matrix attachment regions (MARs) of DNA. However, the functional significance of NMPs in glioblastoma (GBM) progression remains unclear. …”
Get full text

Novel Vanadium-Loaded Ordered Collagen Scaffold Promotes Osteochondral Differentiation of Bone Marrow Progenitor Cells by Ana M. Cortizo, Graciela Ruderman, Flavia N. Mazzini, M. Silvina Molinuevo, Ines G. Mogilner

“…Bone and cartilage regeneration can be improved by designing a functionalized biomaterial that includes bioactive drugs in a biocompatible and biodegradable scaffold. …”
Get full text

Evaluating Vegetable Oil Epoxidation Efficiency on Properties of Eucalyptus Wood: Thermal and Thermo-chemical Processing by Seyed Javad Hejazi, Raoufeh Abedini, Maryam Ghorbani, Foroogh Dastoorian

“…This study compared the effect of oil heat treatment (OHT) with raw (SO) and epoxidized soybean oil (ESO) at different temperatures relative to the practical properties of eucalyptus wood. …”
Get full text

Cortical thickness deviations as biomarker for subtyping and prognosis in pediatric brainstem tumors by Heyuan Jia, Kaikai Wang, Peng Zhang, Mingxin Zhang, Yiying Mai, Congying Chu, Xuntao Yin, Lingzhong Fan, Liwei Zhang

“…Abstract Brainstem tumors exert profound effects on cortical organization and functionality across the whole brain. …”
Get full text

Metagenomic Analysis Revealed the Changes in Antibiotic Resistance Genes and Heavy Metal Resistance Genes in Phosphate Tailings Compost by Chunqiao Xiao, Kai Wan, Yan Chen, Yongtong Jin, Fang Zhou, Junxia Yu, Ruan Chi

“…The addition of phosphate tailings combined the functions of chemical regulation and nutrient enrichment, and its synergistic effect significantly optimized the nutrient cycling in the composting system.…”
Get full text

Advancing geohazard risk assessment – A digital tool for steep slope management by Cherry Rose Godes, One-Bin Lim, Shanelle Aira Rodrigazo, Yongseong Kim, Yongjin Kim, Seungjoo Lee, Jaeheum Yeon

“…Future research should extend pilot studies across diverse regions and climatic conditions to refine its functionality and facilitate broader adoption in disaster risk management practices.…”
Get full text

A Comprehensive Overview of Heritage BIM Frameworks: Platforms and Technologies Integrating Multi-Scale Analyses, Data Repositories, and Sensor Systems by Carmen Fattore, Michele Buldo, Arcangelo Priore, Sara Porcari, Vito Domenico Porcari, Mariella De Fino

“…In this context, this paper presents a scoping review, based on the PRISMA protocol, of 60 publications from the Scopus database that document research frameworks and applications of IDPs (integrated digital platforms), where HBIM is combined with different systems to enhance data richness, functionality, and analytical evaluation, as well as to exchange, interpret, and use information effectively. …”
Get full text

The antioxidant system was unexpectedly strongly suppressed in apis mellifera worker bees emerged from larvae reared on combs adulterated with paraffin or stearin by Aneta Strachecka, Patrycja Staniszewska, Krzysztof Olszewski, Magdalena Chęć, Mariusz Gagoś, Piotr Dziechciarz, Maciej S. Bryś, Jerzy Paleolog

“…Abstract The bee-wax combs are “the biggest organ of the bee colony body” as, in addition to their structural functions, they transfer information – pheromones and sounds. …”
Get full text