Effect of Diet on HDL in Obesity by Tiziana Bacchetti, Camilla Morresi, Oriana Simonetti, Gianna Ferretti

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Investigation of cardiotoxic effects of marbofloxacin by Devran Coşkun, Burak Dik, Yasemin Korkmaz, Rahmi Canbar, Ayşe Er, Enver Yazar

“…While marbofloxacin did not cause (P<0,05) any adverse effect on liver function parameters, it caused (P<0,05) increase BUN levels and fluctuations in creatinine levels which were renal function values. …”
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Effect of vitamin D supplementation by Jan Biłogras, Kornelia Karamus, Rafał Rejmak, Martyna Borowska-Łygan, Jakub Tomaszewski, Konrad Strużek, Wojciech Urban

“…Conclusions Based on the accumulated studies, it can be concluded that vitamin D contributes to the improvement of immune system function. Some studies prove the beneficial effect of vitamin D supplementation on the course of some autoimmune diseases. …”
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The effect of acute exercise on cognition by Blanka Dwojaczny, Sergii Iermakov, Tatiana Yermakova, Mirosława Cieślicka

“…The majority of studies focused on the chronic effects of exercise. Relatively limited number of reports addresses the problem of influence of acute exercise (single bouts of exercise) on cognitive functions. …”
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Effectiveness of preeclampsia prognosis in pregnancy by Loskutova T.O.

“…With the purpose to develop and assess the effectiveness of prediction method of pre-eclampsia (PE) 177 women in III trimester of pregnancy were examined. …”
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Ultra-High-Molecular-Weight Polyethylene Rods as an Effective Design Solution for the Suspensions of a Cruiser-Class Solar Vehicle by Giangiacomo Minak, Tommaso M. Brugo, Cristiano Fragassa

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Medical data security and effective organization using integrated Blockchain principles in AI-based healthcare 6.0 infrastructures by Mohammad Gouse Galety, Kuan Tak Tan, Pravin R. Kshirsagar, Subba Rao Polamuri

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Nav1.8 and Chronic Pain: From Laboratory Animals to Clinical Patients by Yu-Feng Xie

“…As a subtype of voltage-gated sodium channel and predominantly expressed in the sensory neurons located in the dorsal root ganglion (DRG), the Nav1.8 channel encoded by the <i>SCN10A</i> gene is found to have different variants in patients suffering chronic pain or insensitivity to pain due to the gain-of-function or loss-of-function of Nav1.8 channels. In animal models of chronic pain, Nav1.8 is also verified to be involved, suggesting that Nav1.8 may be a potential target for treatment of chronic pain. …”
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Optimizing the neural network and iterated function system parameters for fractal approximation using a modified evolutionary algorithm by Sana Abdulla, K. Mahipal Reddy

“…However, optimizing the parameters of Iterated Function System (IFS)-based fractal interpolants remains a challenging task, particularly for Rational Fractal Cubic (RFC) splines, which offer greater flexibility in shape control. …”
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Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system by Y.  H. Dang, Elise Dauzat, Asif Istiak, Kevin Jackson, Victoria Songe, Luke West, Md Imrul Kayes, Md Saiful Islam, Tanvir R. Faisal

“…3D bioprinting has emerged as a transformative technology in biomedical engineering, enabling the fabrication of functional tissues through the precise deposition of cell-laden biomaterials. …”
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Determining the Cost-Effective Methods for Heat Exchanger Maintenance Using Extreme Value Analysis (EVA) Ask ChatGPT by Anne Ting Ai Nee, Ainul Akmar Mokhtar, Noor Hazliza A Latip, Farah Nur Faizul, Nurul Hazwani Azmi

“…This evaluation is critical for forecasting the functional lifespan of the heat exchangers and deciding whether tube plugging, retubing, or replacement is the most cost-effective option against operational risk during the upcoming planned shutdown or turnaround phase. …”
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Multidimensional seismic fragility analysis of subway station structures using the adaptive bandwidth kernel density estimation and Copula function by Chunyi Cui, Jingtong Zhao, Minze Xu, Chengshun Xu, Hailong Liu, Kunpeng Wang

“…Subsequently, the Copula function is used to formulate a bivariate seismic fragility function considering the correlations among seismic demand measures and establish the corresponding fragility curves. …”
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Enhancement in the Electrocatalytic and Optoelectronic Performance of Cost-Effective Counter Electrode VO2 for Dye-Sensitized Solar Cell (DSSC) by Varsha Yadav, Rahul Bhatnagar, Upendra Kumar

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An innovative constructional and technical method of using a prefabricated, dowelled reinforced concrete slab for effective repairs of airport pavements by Bartosz Swierzewski, Mariusz Wesolowski

“…The repair method consisting in the use of a prefabricated airport slab in the place of excessive degradation of existing slabs introduces a pioneering method of connecting slabs with adjacent slabs, creating a new construction quality that increases the spatial stiffness of the entire functional element of the pavement. The performed dimensioning and static - strength analysis of the prefabricated airport slab using the finite element method in the aspect of the global state of effort of the structure confirmed that the technical solution with the use of a dowel joint was properly designed, because it has a positive effect on the redistribution of loads transfer between cooperating prefabricated slabs. …”
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Enhancing the antibacterial ability of Ligilactobacillus salivarius through ARTP mutagenesis breeding: an effective strategy to improve its probiotic properties by Hetian Zhou, Hetian Zhou, Hetian Zhou, Yunping Du, Guolian Yu, Wei Liu, Juanjuan Zeng, Bin Wang, Bin Wang, Maojin Chen, Yujue Wang, Wenbo Zhang, Xiaona Wei, Xiaona Wei

“…IntroductionLigilactobacillus salivarius (L. salivarius), a well-characterized probiotic species with established safety and functional efficacy, has been widely applied in poultry production for decades. …”
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Clinical Value of Continuous Fascia Iliaca Compartment Block in Perioperative Management of Elderly Patients with Intertrochanteric Fracture: A Propensity Score-Matched Retrospecti... by Xu G, Deng Y, Gao H, Wang B, Wang G, Ma J

“…Complication rates were comparable between groups (22.5% vs 17.5%, P = 0.576).Conclusion: CFICB effectively improves postoperative pain management, reduces cognitive dysfunction incidence, and enhances early functional recovery in elderly patients with intertrochanteric fractures, while maintaining a favorable safety profile.Keywords: continuous fascia iliaca compartment block, intertrochanteric fracture, cognitive function, postoperative pain, hip joint function, elderly patients, regional anesthesia…”
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Formation of an effective labor incentive system to increase the efficiency of an enterprise (on the example of the Tuapse department of the Azovo-Chernomorsky basin branch) by A. K. Dorgushaova, T. S. Kuzina

“…This article substantiates the effectiveness of incentives for employees, notes the appropriateness of the forms and methods of incentives chosen by the enterprise. …”
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Evaluation of porphyrin molecules as effective corrosion inhibitors for copper alloy in sulfuric acid using both experimental and computational approaches by Metwally Abdallah, Majda Alfakeer, Rasha N Felaly, Abdulaziz M. Almohyawi, Jabir H. Al-Fahemi, Salih S. Al-Juaid, Doaa F. Seyam, Elsayed M. Mabrouk, Kamal A. Soliman

“…Some chemical, electrochemical measurements, density functional theory and Monte Carlo simulations were utilized to study the adsorption behaviour and corrosion inhibition efficiency of m-TMPP and p-TMPP on the Cu (111) surface in acidic media. …”
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Analysis of possible markers of effective antitumor cellular immune response before starting therapy with immune check-point inhibitors by A. M. Malkova, R. V. Orlova, N. V. Zhukova, A. R. Gubal, V. V. Sharoiko

“…The aim of the study. to analyse possible markers of an effective antitumor cellular immune response.Material and methods. using the keywords «checkpoint inhibitors, immunotherapy, t-lymphocytes, exhausted t-lymphocytes, anti-tumor immune response», review and original articles (n=34) published from 2005 to 2020 in the Pubmed, Web Of Science, Elsevier databases were selected.Results. the study revealed possible markers reflecting a high activity of an adaptive immune response based on effective recognition of tumor antigens through MHC molecules, a sufficient number of T-lymphocytes and a predominance of T-cytotoxic cells, as well as a low level of expression of inhibitory receptors and small molecules. the presence of single nucleotide polymorphisms in the HLA-I and HLA-II genes encoding MHC-I and MHC-II proteins, respectively, a high level of lymphocytes, among which the most important is the predominance of CD8+ t cells and a low level of T-regulatory cells (T-reg), as well as the presence of single nucleotide polymorphisms in the genes encoding FcγR receptors of T-lymphocytes showed their predictive significance. the diagnostic significance of determining the expression of inhibitory receptors for T-lymphocytes (TIM3, LAG3, TIGIT), especially in combination with the determination of PD-1 expression, was also revealed.Conclusion. the results obtained may be relevant for applying new methods for the assessment of the functional activity of the T-cell immune response before starting therapy with checkpoint inhibitors, as well as for the development of new diagnostic panels, which may be of interest to employees of clinical diagnostic laboratories and research centers.…”
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Optimized lipid nanoparticles enable effective CRISPR/Cas9-mediated gene editing in dendritic cells for enhanced immunotherapy by Kuirong Mao, Huizhu Tan, Xiuxiu Cong, Ji Liu, Yanbao Xin, Jialiang Wang, Meng Guan, Jiaxuan Li, Ge Zhu, Xiandi Meng, Guojiao Lin, Haorui Wang, Jing Han, Ming Wang, Yong-Guang Yang, Tianmeng Sun

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