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67241
Lenvatininb as Treatment for Naïve Patients with Aggressive Thyroid Cancer Bone Metastases and Bad Performance Status
Published 2020-01-01“…Lenvatinib is an oral multityrosine kinase inhibitor (TKI) with proven effectiveness in the treatment of radioactive iodine- (RAI-) refractory and/or unresectable differentiated thyroid carcinoma (DTC). …”
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67242
Response of dorsal horn neurons in mice to high‐frequency (kHz) biphasic stimulation is not sensitive to local temperature rise
Published 2025-02-01“…This is equivalent to the release of more heat in a surrounding tissue, which may change the functional state of affected neural elements. In the case of SCS, plausible candidates to be affected by thermal a component of kHz‐frequency electric field stimulation (kHz‐FS) are dorsal column axons and neurons of the superficial layers of the dorsal horn. …”
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67243
Multi-dimensional spatial and temporal dynamics of environmental stress and driving factors in the Baiyangdian Basin, China
Published 2025-08-01“…Furthermore, the Baiyangdian Basin is delineated into four ecological functional zones, providing a scientific basis for refined basin-scale ecological management and sustainable development. …”
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67244
An innovative tool for the evaluation of energy efficiency of merchant ships
Published 2025-01-01“…The application of the tool to a case study of a tanker ship, designed to validate its functionality, demonstrates that the tool can effectively generate extensive data, which can be used to identify correlations between specific ship factors and GHG emissions. …”
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67245
Assessment of Post-COVID-19 Syndrome and Its Relationship to Age, Sex, and Comorbid Disease in Iraqi Population
Published 2025-01-01“…Follow-up may be required to minimize the effects of post-COVID-19 syndrome on general health and quality of life for affected patients.…”
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67246
An Emergency Response Framework Design and Performance Analysis for Ship Fire Incidents in Waterway Tunnels
Published 2025-07-01“…A Colored Hierarchical Timed Petri Net (CHTPN) emergency response model is then developed based on fire incident data and emergency response time functions. Furthermore, a homomorphic Markov chain is employed to assess the network’s validity and performance. …”
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67247
Enhancing palbociclib efficacy with low toxicity in breast cancer using polycaprolactone-based nanocarriers
Published 2025-05-01“…Breast cancer, stands as a prevalent form of cancer that results in a significant number of fatalities annually. Palbociclib (PAL) functions by impeding the activity of CDK4 and CDK6 proteins, thereby halting the division and generation of new cells within the body. …”
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67248
Buffering the Impact of Loneliness on Academic Stress: The Moderating Power of Self-Compassion
Published 2024-12-01“…These findings demonstrate that self-compassion functions as an emotional coping resource capable of reducing stress associated with social isolation. …”
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67249
Optimizing the Spectrum and Power Allocation for D2D-Enabled Communication Systems Using DC Programming
Published 2020-01-01“…The difference of convex functions (DC) programming is adopted to solve the power allocation problem. …”
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67250
Appropriate Hydration Can Make a Difference
Published 2021-12-01“…Dehydration has remarkable consequences including effect on body temperature, respiratory rate, mental functioning and muscle endurance. …”
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67251
Activities of Administrative Judiciary During Marital State in Ukraine
Published 2025-07-01“…Emphasis is placed on the need to ensure the functioning of the judicial system even in conditions of active hostilities, because according to Article 124 of the Constitution of Ukraine and the Law of Ukraine “On the Legal Regime of Martial Law”, courts are obliged to continue their activities and cannot limit their powers. …”
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67252
Exploring Molecular Alterations in Breast Cancer Among Indian Women Using Label-Free Quantitative Serum Proteomics
Published 2024-01-01“…Conclusively, this study recognizes prospective biomarkers for breast cancer among Indian women and highlights the requisite of in-depth functional studies to elucidate their precise roles in breast cancer development. …”
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67253
Evaluating Correlations between a Seaport and Its Dry Ports: Case Study of Xiamen Port in China
Published 2018-01-01“…The paper then carries out case studies on Xiamen Port and its six dry ports to verify the effectiveness of the method and model in the paper. The study results show that Xiamen Port has very high region-varying correlations with its hinterland dry ports. …”
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67254
Melanocortin-4 Receptor Deficiency Phenotype with an Interstitial 18q Deletion: A Case Report of Severe Childhood Obesity and Tall Stature
Published 2016-01-01“…This case supports haploinsufficiency of MC4-R as it describes a MC4-R deficiency phenotype in a patient heterozygous for a full MC4R gene deletion. The intact functional allele with MC4-R haploinsufficiency has the potential to favor a therapeutic response to gastric surgery. …”
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67255
Developing Talent from a Supply–Demand Perspective: An Optimization Model for Managers
Published 2017-08-01“…We first develop a multi-period mixed integer nonlinear programming model and then exploit chance-constrained programming to a linearized instance of the model to handle stochastic parameters, which follow any arbitrary distribution functions. Next, we use an empirical study to validate the model with a large global manufacturing company, and demonstrate how the proposed model can effectively manage talents in a practical context. …”
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67256
Conflicts, Compromises and Professionalization. The Case of Hungarian Trainee Lawyers in the late 19th Century
Published 2023-11-01“…The relationship between the two groups is important because, in addition to lawyers, trainee lawyers also have gained important functions through the lawyer’s code of conduct introduced in 1874, which have further increased the already fierce competition in the labour market for lawyers. …”
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67257
An Adaptive Ant Colony System Memorizing Better Solutions (aACS-MBS) For Traveling Salesman Problem
Published 2021-06-01“…With the pheromone maps formed as a result of the search, the effect of transfer functions was evaluated. Results obtained with aACS-MBS were compared with different ant colony optimization (ACO) algorithms. …”
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67258
Attachment Theory and Physical Well-Being
Published 2025-09-01“…Unsafe internal attachment patterns have a negative impact on the development of a wide range of somatic pathologies, primarily cardiovascular and immune systems, and impaired functioning of the HPA axis, mediated by associative anxiety. …”
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67259
Applying the L3 assessment framework to identify knowledge gaps on the impact of classroom activities and listening on children’s learning and wellbeing
Published 2024-12-01“…The aims of this paper were to (i) understand what is known and what is not known about how the characterised activity impacts primary school children’s learning and wellbeing, and (ii) understand what is known and what is not known about how hearing, listening, comprehending, and communicating (Functioning Assessment) impacts primary school children’s learning and wellbeing. …”
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67260
Resilience of Urban Road Network to Malignant Traffic Accidents
Published 2022-01-01“…Malignant traffic accidents are typical devastating events suffered by the urban road network. They cause severe functional loss when loading on the urban road network is high, exerting a significant impact on the operation of the city. …”
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