Recent advances on the mechanism of acupuncture in the treatment of subjective tinnitus by Feifei Shi, Ziyu Ye, Bixiang Zha, Weixian Wu, Yating Zhang, Leiyu Yu, Wanting Liu, Yan Rong, Jun Yang

“…Additionally, the modulation of the thalamus and the functional reorganization of the auditory cortex and synaptic network may contribute to the achievement of therapeutic effects.ConclusionWhile acupuncture has demonstrated clinical efficacy in the treatment of subjective tinnitus, the underlying mechanism of action remains poorly understood. …”
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Advances in the study of artemisinin and its derivatives for the treatment of rheumatic skeletal disorders, autoimmune inflammatory diseases, and autoimmune disorders: a comprehens... by Zhiyong Long, Wang Xiang, Wei Xiao, Yu Min, Fei Qu, Bolin Zhang, Liuting Zeng

“…Ongoing multicenter randomized clinical trials are investigating the effects of these compounds on rheumatic, inflammatory, and autoimmune diseases, with the aim of translating promising preclinical data into clinical applications.…”
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Ultrafast ROS Scavenging Activity of Amur Maple Tree Extracts Confers Robust Cardioprotection for Myocardial Ischemia/Reperfusion Injury by Aoyang Pu, Woo-Sup Sim, Yuen-Kei Liem, Yimin Lai, Bong-Woo Park, Kyoung-Tae Lee, Hun-Jun Park, Kiwon Ban

“…When co-administered for 30 min, the DCM- and EA-fractioned extracts effectively protected cardiomyocytes from H₂O₂-induced damage. …”
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Treating Complex Trauma in Adolescence: A Case Study of Brief Focal Psychotherapy After Vicarious Gender Violence and Child Abuse by Georgina Rosell-Bellot, Eva Izquierdo-Sotorrío, Ana Huertes-del Arco, María Rueda-Extremera, María Elena Brenlla

“…This case highlights the potential of BFP in addressing complex trauma in adolescents, particularly during a developmental stage marked by increased vulnerability to the effects of chronic trauma exposure. The findings suggest that BFP can effectively reduce both acute symptomatology and broader psychosocial consequences associated with prolonged and cumulative trauma. …”
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The Application of Variable Weight Theory on the Suitability Evaluation of Urban Underground Space Development and Utilization for Urban Resilience and Sustainability by Hongnian Chen, Xianfeng Tan, Yan Zhang, Bo Hu, Shuming Xu, Zhenfen Dai, Zhengxuan Zhang, Hanxiang Xiong, Xiaoqing Song, Danyuan Luo

“…These sensitive factors often exhibit a “barrel effect”, showing the power to either definitively affirm or veto the outcomes. …”
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The Roxadustat (FG-4592) ameliorates tubulointerstitial fibrosis by promoting intact FGF23 cleavage by Jing Wang, Zuo-Lin Li, Yan Zhou, Zhong-Tang Li, Yan Tu, Xin-Hui Hu, Jin-Hua Zhu, Bi-Cheng Liu, Hong Liu

“…Abstract Background Hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) represents a novel therapeutic approach for renal anemia, a prevalent complication of chronic kidney disease (CKD). However, the effects of HIF-PHI on renal functional outcomes remain poorly characterized. …”
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Multifaceted impacts of double-aging neighborhood’s built environments on SAIP: a deep dive into Chinese rapidly aging urban society by Yue Qian, Guanmin Qiao, Guanmin Qiao, Guanmin Qiao, Guoping Zhang, Xianjing He, Renfeng Ma, Renfeng Ma, Renfeng Ma

“…Especially, community participation has a positive impact, serving as an extension of the home space, such as college for senior citizens and outdoor activity space; (3) The built environment of double-aging neighborhoods has a significant positive effect, with a sense of place identity replacing the reliance on family members and acquaintances to facilitate SAIP; (4) In high-density old district, the distribution of public facilities is saturated, and the proper utilizes of these facilities becomes an important factor affecting SAIP.DiscussionWe provide a multi-factorial perspective of SAIP, demonstrating the compensatory and substitutional roles of community-based older adults care services and friendly neighborhood relationships in fulfilling home-based older adults care functions. …”
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Comparative study of topical 5-aminolevulinic acid photodynamic therapy and surgery in treating vaginal high-grade squamous intraepithelial lesions following hysterectomy by Bingjie Wang, Chunyan Zhang, Yuehui Su, Shuyu Yuan, Mengjiao Zhou, Mengzhuo Zhang, Yingying Zhou, Lili Cao, Mengzhen Zhang, Ting Zhang

“…In women treated with ALA-PDT, there was no vaginal bleeding or harmful effects on the organizational structure or functions compared to the surgery group. …”
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TRPC6-targeted dexamethasone nanobubbles with ultrasound-guided theranostics for adriamycin-induced nephropathy by Lin Wu, Yang Liu, Ziqi Fu, Honglei Guo, Kang Liu, Jiafa Ren, Zhimin Huang, Fang Yang, Huijuan Mao

“…Comprehensive in vivo and in vitro evaluations demonstrated the robust kidney and podocyte-targeting capabilities of Dex@NBs-TRPC6. Functional assays in mouse podocyte cells revealed that Dex@NBs-TRPC6 significantly outperformed free Dex and non-targeted nanobubbles (Dex@NBs) in mitigating cell apoptosis and inflammation. …”
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Acupuncture for acute non-specific low back pain: a randomised, controlled, multicentre intervention study in general practice—the Acuback study by Ibrahimu Mdala, Margreth Grotle, Mette Brekke, Trygve Skonnord, Holgeir Skjeie, Atle Klovning, Eline Aas, Arne Fetveit

“…Secondary outcomes were pain intensity, global improvement, back-specific functional status, sick leave, medication and adverse effects.Results 185 participants were randomised, 95 in the CG and 90 in the AG. 14 participants did not receive the allocated intervention and 4 were excluded from the analysis. …”
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Maternal diet shapes infant microbiota and defensive capacity against infections in early life via differential human milk compositionResearch in context by Karla Rio-Aige, Marta Selma-Royo, Raúl Cabrera-Rubio, Sonia González, Cecilia Martínez-Costa, Margarida Castell, María J. Rodríguez-Lagunas, María Carmen Collado, Francisco J. Pérez-Cano

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Vaginal progesterone pessaries for pregnant women with a previous preterm birth to prevent neonatal respiratory distress syndrome (the PROGRESS Study): A multicentre, randomised, p... by Caroline A Crowther, Pat Ashwood, Andrew J McPhee, Vicki Flenady, Thach Tran, Jodie M Dodd, Jeffrey S Robinson, PROGRESS Study Group

“…The withdrawal of progesterone, either actual or functional, is thought to be an antecedent to the onset of labour. …”
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Underlying anti-hypertensive mechanism of the Mizuhopecten yessoensis derived peptide NCW in spontaneously hypertensive rats via widely targeted kidney metabolomics by Wenjun Xue, Wenzhu Zhao, Sijia Wu, Zhipeng Yu

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Headache in radiologically isolated syndrome: a hint toward imminent conversion: a case report by Masoud Etemadifar, Hasan Kaveyee, Parto Zohrabi, Amir Mohammad Jozaie, Mehri Salari, Yasin ebne-ali-heydari

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Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials. by Harsha Shanthanna, Ian Gilron, Manikandan Rajarathinam, Rizq AlAmri, Sriganesh Kamath, Lehana Thabane, Philip J Devereaux, Mohit Bhandari

“…We aimed to assess the effectiveness and safety of gabapentinoids in adult CLBP patients.…”
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GNSS Precipitable Water Vapor Prediction for Hong Kong Based on ICEEMDAN-SE-LSTM-ARIMA Hybrid Model by Jie Zhao, Xu Lin, Zhengdao Yuan, Nage Du, Xiaolong Cai, Cong Yang, Jun Zhao, Yashi Xu, Lunwei Zhao

“…Enhanced by local mean optimization and adaptive noise regulation, the ICEEMDAN algorithm effectively suppresses pseudo-modes and minimizes residual noise, enabling its decomposed intrinsic mode functions (IMFs) to more accurately capture the multi-scale features of GNSS-PWV. …”
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The Remarkable and Selective In Vitro Cytotoxicity of Synthesized Bola-Amphiphilic Nanovesicles on Etoposide-Sensitive and -Resistant Neuroblastoma Cells by Silvana Alfei, Paolo Giannoni, Maria Grazia Signorello, Carola Torazza, Guendalina Zuccari, Constantinos M. Athanassopoulos, Cinzia Domenicotti, Barbara Marengo

“…Triphenyl phosphonium salts (TPPs) are mitochondria-targeting compounds that exert anticancer effects, impair mitochondria functions, and damage DNA at the same time. …”
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Investigating the Magnitude and Persistence of COVID-19–Related Impacts on Affect and GPS-Derived Daily Mobility Patterns in Adolescence and Emerging Adulthood: Insights From a Sma... by Jordan D Alexander, Kelly A Duffy, Samantha M Freis, Sy-Miin Chow, Naomi P Friedman, Scott I Vrieze

“…The study highlights both youth’s resiliency in adapting to major stressors while also underscoring the need for continued support for youth mental health and psychosocial functioning in the pandemic’s aftermath.…”
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Network pharmacology integrated with molecular docking and experimental validation elucidates the therapeutic potential of Forsythiae Fructus extract against hepatitis B virus-rela... by Fuqing Chen, Yifan Cai, Changzhou Chen, Jianyin Zhou

“…Notably, adenovirus-mediated overexpression experiments showed that ESR1 enhanced FF’s anti-HCC effects, whereas JUN and MMP9 partially counteracted them, confirming their roles as functional targets. …”
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Antepartum high dietary supply of calcium affects bone homeostasis and offspring growth in dairy sheep and dairy goats by D. Brugger, A. Liesegang

“…We conclude that although dairy sheep and goats effectively managed high dietary Ca intake without overt signs of hypocalcemia or milk fever under these experimental conditions, the observed effects on offspring growth and potential long-term physiological effects warrant further investigation. …”
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