EVALUATION OF THE DYNAMICS OF OCCLUSION RATIO DURING ORTHODONTIC TREATMENT OF PATIENTS WITH PERMANENT BITE. by K.M. Lykhota

“…Investigation of violations of occlusion of dentitions is an integral part of the complex functional analysis of the dental maxillary apparatus. …”
Get full text

Synthesis, toxicity and antioxidant activity of phenolic benzimidazole derivatives: In vitro and in silico studies by Mithun Rudrapal, Mohammad Mojammil, Azmal Farooque, Masoom Ansari, André M. de Oliveira, Johra Khan

“…Acute toxicity tests assessed in zebrafish reveals a concentration-dependent toxic effect. 3a lethal dose measured to kill 50 % of test fishes was 3.163 mg/L, and 1.88 mg/L for 3b Antioxidant activity was determined using the DPPH radical scavenging assay, with compound 3a demonstrating higher radical scavenging efficiency than 3b Molecular docking studies indicated that both compounds interact with NAD(P)H oxidase, with 3b showing a stronger binding affinity due to additional functional groups facilitating enhanced interactions, with H-bond interactions between 3a phenolic OH and Pro 696 and between benzimidazole NH and Asn 710, as well as H-bond interaction between 3b benzimidazole NH and Glu 482, and steric interactions between 3b O-ether and Tyr 481 and between aromatic ring and Ser 564. …”
Get full text

Pioneering evaluation in Brazil of microscope-integrated optical coherence tomography with a three-dimensional digital visualization system during pars plana vitrectomy for the tre... by Leticia Pinheiro de Freitas, Jamil Miguel Neto, Laís Lauria Neves, Thais Bastos, Alexandre Caiado Ferreira Pires, Antônio Marcelo Barbante Casella, David Leonardo Cruvinel Isaac, Marcos Pereira de Ávila

“…These findings suggest that in the near future, expanded use of iOCT could significantly improve tissue management at the vitreomacular interface and improve anatomical and functional results.…”
Get full text

Enhanced THBS2 promotes collagen synthesis and inflammatory secretome of fibroblasts in idiopathic pulmonary fibrosis by Lu Yu, Rui Wang, Qinhui Hou, Fan Yang, Ying Liu, Meiting Peng, Yihan Dong, Yuan Liu, Zhenshun Cheng

“…Abstract The pathogenesis of pulmonary fibrosis involves structural remodeling and functional impairment of lung tissue, accompanied by increased secretion of pro-inflammatory mediators and abnormal synthesis of the extracellular matrix (ECM). …”
Get full text

Development and Test of Pomelo Fruit Inventory Grading Management System Based on RFID Technology by Haijun QI, Jintao ZHANG, Bofeng ZENG, Yizhi LUO, Xingxing ZHOU

“…【Conclusion】The pomelo fruit inventory grading management system can realize the functions such as grading warehousing, grading management in the warehouse, and grading outbound traceability of pomelo fruit, which effectively improves the work efficiency, digital management level, and overall benefits of pomelo fruit processing and distribution enterprises.…”
Get full text

The m6A reader IGF2BP2 promotes pancreatic cancer progression through the m6A-SLC1A5-mTORC1 axis by Xi Pu, Yuting Wu, Weiguo Long, Xinyu Sun, Xiao Yuan, Deqiang Wang, Xu Wang, Min Xu

“…Disrupting m6A regulation of glutamine metabolism could impair tumor growth, offering potential new therapeutic strategies. However, the functional role of m6A modifications in pancreatic cancer, especially in glutamine metabolism, remains poorly understood. …”
Get full text

Survivorship in robotic total knee arthroplasty compared with conventional total knee arthroplasty: A systematic review and meta-analysis by Jiawei Chen, Ryan Wai Keong Loke, Katelyn Kaye-Ling Lim, Barry Wei Loong Tan

“…Secondary outcomes included associated complications, post-operative pain scores, and functional outcomes. Results A total of 20 comparative studies were included in the meta-analysis. …”
Get full text

Progressive Response of Repeated Treatment with High-Concentration (179 mg) Capsaicin Patch in Peripheral Neuropathic Pain After Surgical or Traumatic Nerve Injury: Findings from t... by Michael A. Überall, Christian Simanski, Mike Zellnig, Mariëlle Eerdekens, Sylvia Engelen, Myriam Heine, Fabienne Percot, Rita Freitas, Lucia Garcia Guerra, Tamara Quandel

“…This study utilizes data from the German Pain e-Registry (GPeR) to investigate the real-world effectiveness of HCCP in managing PNI across multiple treatments over 1 year. …”
Get full text

Comparing Injection Methods of Botulinum Toxin A for Cervical Dystonia: A Systematic Review by Hristo Shipkov, Petar Uchikov, Abdulrahman Imran, Zain Ul Hassan, Ivan Grozdev, Krasimir Kraev, Maria Kraeva, Nina Koleva, Maria Bozhkova, Stanislav Karamitev

“…Background: Cervical dystonia (CD) is a chronic neurological disorder characterized by involuntary neck muscle contractions, leading to abnormal head postures, pain, and functional impairment. Botulinum toxin type A (BoNT-A) remains the treatment of choice, but its efficacy is highly dependent on injection accuracy. …”
Get full text

Serum and urinary biomarkers for early detection of acute kidney injury following Hypnale spp. envenoming. by Eranga Sanjeewa Wijewickrama, Fahim Mohamed, Indika B Gawarammana, Zoltan H Endre, Nicholas A Buckley, Geoffrey K Isbister

“…We aimed to identify the value of functional and injury biomarkers in predicting the development of AKI early following HNV bites.…”
Get full text

Minimally invasive treatment of grade I and II gluteal muscle contracture using a self-made special cutter combined with a specialized compression hemostasis device by Yingguo Yang, Zixuan Peng, Linlin Shi, Ye Wang, Yuan Wang, Bing Ge, Dongcheng Zhu, Zhiyuan Ye

“…Additionally, it causes less trauma, simplifies the operation, reduces intraoperative and postoperative bleeding, allows for early functional exercise, and promotes rapid functional recovery. …”
Get full text

Dynamic relationship between gut microbiota and post-necrotizing pancreatitis: insights from a multi-stage 16S rRNA sequencing study by Jiongdi Lu, Jiongdi Lu, Zhe Wang, Zhe Wang, Feng Cao, Feng Cao, Jia Li, Guofeng Ji, Guofeng Ji, Fei Li, Fei Li

“…Gut microbial diversity and composition were assessed using 16S rRNA sequencing, followed by bioinformatic analyses such as Alpha and Beta diversity metrics, linear discriminant analysis effect size (LEfSe), and functional pathway predictions. …”
Get full text

Relationships Between Photosynthetic Efficiency and Grain Antioxidant Content of Barley Genotypes Under Increasing Nitrogen Rates by Rafał Nowak, Małgorzata Szczepanek, Joanna Kobus-Cisowska, Kinga Stuper-Szablewska, Radomir Graczyk, Karolina Błaszczyk

“…Nitrogen fertilization may affect the functioning of photosynthesis as well as the chemical composition and antioxidant potential of cereal grains. …”
Get full text

p65/miR‐23a/CCL22 axis regulated regulatory T cells recruitment in hepatitis B virus positive hepatocellular carcinoma by Zhi‐Qin Li, Hong‐Yan Wang, Qing‐Lei Zeng, Jing‐Ya Yan, Yu‐Shu Hu, Hua Li, Zu‐Jiang Yu

“…Xenograft tumor models were developed to investigate the functions of p65 and miR‐23a in vivo. Results HBV infection was associated with reduced survival and increased Tregs recruitment in HCC patients. …”
Get full text

Automated Recipe Generation AI Tool from Food Images using Machine Learning. Approach for Ingredient Extraction and Cooking Instructions by Lwamaza, Eddy, Nuwasiima, Happy

“…It outlines the systematic approach taken to analyze user needs, define functional and non-functional requirements, and develop a robust system architecture. …”
Get full text

Mejoras al programa de mantenimiento de máquinas deslodadoras para la extracción de aceite de palma // Improving the maintenance program of extracting fruit palm oil machines by Jesús Cabrera - Gómez, Henry Araque - Rivas

“…An analysis in order to identify functions, functional</p><p>failures, failure modes and failure effects was made. …”
Get full text

Artistic Features of Jiangnan Gardens During the Mid-16th Century as Reflected in the Picture of a Famous Garden in Jinchang by Shiyuan PANG, Xiao HUANG

“…The development of commodity economy highlighted the social attributes of gardens as venues for social interaction, stimulating garden owners’ attention to the aesthetic functions of their gardens. The transformation of Jiangnan gardens in the mid-16th century originats from the combined effects of social evolution and artistic development. …”
Get full text

Discovery and mechanism verification of first-in-class hydrophobic tagging-based degraders of HBV core protein by Shujing Xu, Ya Wang, Dazhou Shi, Shuo Wang, Lijun Qiao, Ge Yang, Yang Zhou, Xinyong Liu, Shuo Wu, Yuhuan Li, Peng Zhan

Get full text

LC-MS Analysis of the Polyphenolic Composition and Assessment of the Antioxidant, Anti-Inflammatory and Cardioprotective Activities of <i>Agastache mexicana</i> and <i>Agastache sc... by Mihaela-Ancuța Nechita, Alina Elena Pârvu, Ana Uifălean, Sonia Iurian, Neli-Kinga Olah, Timea Henrietta Bab, Rodica Vârban, Vlad-Ionuț Nechita, Anca Toiu, Ovidiu Oniga, Daniela Benedec, Daniela Hanganu, Ilioara Oniga

Get full text

Does the Ischemic Core Really Matter? An Updated Systematic Review and Meta‐Analysis of Large Core Trials After TESLA, TENSION, and LASTE by Mohammad AlMajali, Mahmoud Dibas, Malik Ghannam, Milagros Galecio‐Castillo, Abdullah Al Qudah, Farid Khasiyev, Juan Vivanco‐Suarez, Aaron Rodriguez‐Calienes, Mudassir Farooqui, Sophie L. Shogren, Fawaz AlMajali, Albert Yoo, Edgar Samaniego, Tudor Jovin, Amrou Sarraj, Santiago Ortega‐Gutierrez

“…Secondary outcomes included functional independence (mRS score 0–2), independent ambulation (mRS score 0–3), 90‐day mortality, and symptomatic intracranial hemorrhage. …”
Get full text