Showing 66,581 - 66,600 results of 73,353 for search 'effective function', query time: 0.45s Refine Results
  1. 66581
  2. 66582
  3. 66583

    Phenome-wide association studies between SERINC2 and neuropsychiatric disorders by Ping Liu, Xinqun Luo, Liping Cao, Yong Zhang, Jiawu Ji, Xiaoping Wang, Kesheng Wang, Xinghua Pan, Ruilan Yang, Zewen Tan, Yunlong Tan, Chiang-shan Li, Xiaoyun Guo, Zhiren Wang, Xingguang Luo, Xingguang Luo

    Published 2025-01-01
    “…SNP-disease associations were tested and then meta-analyzed, followed by FDR correction, to identify significant disease-risk SNPs. Finally, functional studies on the differential SERINC2 mRNA expression in brains and the potential regulatory effects of disease-risk alleles on SERINC2 mRNA expression, gray matter volumes (GMVs) of subcortical structures, cortical surface area (SA) and average thickness (TH) were conducted.ResultsIn European descent, alcoholism was most significantly associated with SERINC2 variants (245 SNPs with 5.5×10-8≤p ≤ 0.049 and 4.9×10-5≤q ≤ 0.034) that were largely shared across cocaine dependence, marijuana dependence, nicotine dependence, polysubstance dependence, schizophrenia, OCD, and autism (8.2×10-8≤p ≤ 0.050 and 1.9×10-5≤q ≤ 0.049); in Chinese population, bipolar disorder was also significantly associated with SERINC2 variants (10 SNPs: 1.3×10-4≤p ≤ 4.7×10-4 and 0.025≤q ≤ 0.031). …”
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  4. 66584

    Research on NS1 Proteins of Group 2 Tembusu Virus Inhibiting the Production of Duck Type Ⅰ IFN by Yunzhen HUANG, Junqin ZHANG, Linlin LI, Jiawen DONG, Yong XIANG, Ming LIAO, Minhua SUN

    Published 2024-07-01
    “…Further studies revealed that the TMUV-JM NS1 inhibited the expression of type Ⅰ IFN via targeting TBK1, and the NS1 255-352 aa was the functional region of the inhibitory effect. It was found that TMUV-JM NS1 did not interact with TBK1 directly, but reduced the phosphorylation level of TBK1 indirectly, thereby suppressed the expression of type Ⅰ IFN.…”
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  5. 66585

    Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice by Linhui Zhang, Haixia Wang, Zishan Wang, Jianyi Xu, Mengyuan Wang, Wenxin Wang, Qiongshan He, Yun Yu, Dongping Yuan, Guirong Bu, Runze Qiu, Jun Long

    Published 2024-12-01
    “…Resveratrol (RES), a natural compound with anti-inflammatory and cholesterol metabolism regulatory properties, has been shown to influence the maturation and inflammatory functions of DCs. However, its relationship with cholesterol metabolism remains unclear. …”
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  6. 66586

    Randomised controlled clinical trial of a structured cognitive rehabilitation in patients with attention deficit following mild traumatic brain injury: study protocol by Roshan das Nair, Nor Asiah Muhamad, Avril Drummond, Mazlina Mazlan, Norhamizan Hamzah, Vairavan Narayanan, Norlisah Ramli, Nor Atikah Mustapha, Nor Adibah Mohammad Tahir, Li Kuo Tan, Mahmoud Danaee, Sing Yau Goh

    Published 2019-09-01
    “…Secondary: Diffusion Tensor Imaging (DTI) parameters and Goal Attainment Scaling score (GAS).Results Results will include descriptive statistics of population demographics, CogniPlus cognitive program and metacognitive strategies. The effect of intervention will be the effect size of S-NAB scores and mean GAS T scores. …”
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  7. 66587
  8. 66588

    TRAF7 knockdown induces cellular senescence and synergizes with lomustine to inhibit glioma progression and recurrence by Yu Chen, Tongyu Zhou, Rongrong Zhou, Wen Sun, Yan Li, Qiyi Zhou, Dongcheng Xu, Yuxin Zhao, Peihao Hu, Jingrui Liang, Yumeng Zhang, Bin Zhong, Juncheng Yao, Di Jing

    Published 2025-04-01
    “…The interaction between TRAF7 and KLF4 was determined by Co-immunoprecipitation (Co-IP) assays. The functions of TRAF7 combined with lomustine in glioma were assessed by both in vitro, in vivo and patient-derived primary and recurrent glioma stem cell (GSC) assays. …”
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  9. 66589

    Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study by Michael Jöbges, Melanie Tempfli, Melanie Tempfli, Christoph Kohl, Christoph Herrmann, Stefan Kelm, Alexa Kupferschmitt, Alexa Kupferschmitt, Alexa Kupferschmitt, Ida Montanari, Nike Walter, Gerhard Suetfels, Thomas Loew, Volker Köllner, Volker Köllner, Thilo Hinterberger

    Published 2025-01-01
    “…These differences were significant with mild effect sizes. Furthermore, of the 27% of participants with pathological MoCA scores at admission, 63% improved to normative levels during rehabilitation, indicating a significant treatment effect (p ≤ 0.001). …”
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  10. 66590

    Unraveling the impact of global change on glomalin and implications for soil carbon storage in terrestrial ecosystems by Ashutosh Kumar Singh, Chunfeng Chen, Xiai Zhu, Bin Yang, Muhammad Numan Khan, Sissou Zakari, Xiao Jin Jiang, Maria del Mar Alguacil, Wenjie Liu

    Published 2024-12-01
    “…Here, using 530 observations from 107 primary studies, we conducted a global meta-analysis to unravel the effects of multiple GCFs (climate change, plant invasion (PI), wildfire, urbanization, land-use change (LUC), and nutrient addition (nitrogen; N, phosphorus; P, and potassium; K) on two functional GRSP fractions (easily extractable- (EE-) and total- (T-) GRSPs) in terrestrial ecosystems. …”
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  11. 66591
  12. 66592

    Broker bureaucracies: The subsidiary offices of the digitalizing state by Fenna Imara Hoefsloot, Neha Gupta, Dennis Mbugua Muthama, José de Jesús Flores Durán

    Published 2025-06-01
    “…Intermediaries play crucial roles in the implementation and functioning of the state in the transition towards digital governance. …”
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  13. 66593

    Data characterizing a panel of biodegradable cross-linked polyester implants for sustained delivery of an anti-viral drugMendeley Data by Sungmin Jung, Jack Bufton, Zeqing Bao, Wonjoon Cho, Dean Aguiar, Christine Allen

    Published 2025-02-01
    “…To expand the range of polymers available for use, cross-linkable allyl functionalized, polyester copolymers were considered for preparation of disc-shaped, implantable delivery systems for TAF. …”
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  14. 66594

    The potential of pharmacological intervention targeting NEDD4 in glioma by Amjad Z. Alrosan, Enaam M.A. Al Momany, Ghaith B. Heilat, Khaled Alrosan, Amro K. Abu-Safieh, Suhaib A. Khuzaie, Ehab M. Alshalout

    Published 2025-03-01
    “…Conversely, the overexpression of NEDD4 resulted in a reversal of these effects. This review delves into the numerous pathways that NEDD4 is involved in regarding gliomas, a critical ubiquitin ligase in these tumors. …”
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  15. 66595

    Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis by Lovisa Örkenby, Signe Skog, Helen Ekman, Alessandro Gozzo, Unn Kugelberg, Rashmi Ramesh, Srivathsa Magadi, Gianluca Zambanini, Anna Nordin, Claudio Cantú, Daniel Nätt, Anita Öst

    Published 2023-03-01
    “…Abstract Early‐life stress can result in life‐long effects that impact adult health and disease risk, but little is known about how such programming is established and maintained. …”
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  16. 66596

    Gut microbiota profile in newly diagnosed pulmonary tuberculosis patients: an exploratory pilot study in southern India by Tejaswini Baral, Shaik Mohammad Abdul Fayaz, Mohan K. Manu, Chandrashekar Udyavara Kudru, Jitendra Singh, Chiranjay Mukhopadhyay, Mahadev Rao, Kavitha Saravu, Sonal Sekhar Miraj

    Published 2025-08-01
    “…At the genus level, specific taxa were upregulated or downregulated in PTB patients compared to HC. Functional analysis showed a depletion in biosynthesis pathways in PTB patients. …”
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  17. 66597

    Mitochondrial Transplantation: A Novel Therapeutic Approach for Treating Diseases by Xinglu Miao, Pei Jiang, Zhaoping Wang, Weihua Kong, Lei Feng

    Published 2025-06-01
    “…This review provides a comprehensive analysis of the multifaceted roles of mitochondria in health and disease, highlighting their central functions in energy production, antioxidant defense, calcium signaling, apoptosis regulation, and mitochondrial homeostasis maintenance. …”
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  18. 66598

    Fault Location for Active Distribution Network Based on Improved LMD and Energy Relative Entropy by Yanchun XU, Caicai ZHAO, Sihan SUN, Lu MI

    Published 2021-11-01
    “…Then the energy relative entropy of all product functions (PF) after decomposition is calculated. The sum of relative energy entropy of all PF components is the relative energy entropy between sections. …”
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  19. 66599

    Measuring Online Battery AC Resistance Using a DC-DC Converter With Time and Frequency Hybrid Method by Seong-Jong Kim, Hwa-Pyeong Park, Tae-Hwan Jin, In-Jun Lee

    Published 2025-01-01
    “…The power converter can implement the dual functionality of power conversion and online AC resistance measurements and achieve high cost-effectiveness with the addition of only a control algorithm. …”
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  20. 66600

    Woman with cancer: cross-sectional analysis of health-related quality of life and social support by Lilian Miranda Belineli, Eliza Maria Rezende Dázio, Eliane Garcia Rezende, Namie Okino Sawada, Murilo César do Nascimento, Bianca de Moura Peloso-Carvalho, Tábatta Renata Pereira de Brito, Silvana Maria Coelho Leite Fava

    Published 2025-03-01
    “…By identifying the specific types of social support that can improve certain dimensions of quality of life, nursing professionals will be able to plan and implement interventions more effectively.…”
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