Integrative computational approaches identify haptoglobin inhibitors to modulate erythrocyte sedimentation rate in trauma-linked inflammatory and haematological malignancies by Abdulaziz H. Al Khzem, Shaban Ahmad

“…The study also included Density Functional Theory computations and pharmacokinetic profiling to assess these compounds’ suitability further, revealing promising results. …”
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The potent neuroepithelium-promoting activity of Otx2 during gastrulation, as demonstrated by its exogenous epiblast-wide expression in chicken embryos by Naoya Takami, Kagayaki Kato, Koya Yoshihi, Akihito Kawamura, Hideaki Iida, Hisato Kondoh, Hisato Kondoh

“…Owing to these Otx2 functions, Otx2-expressing anterior epiblast cells develop into vast amounts of brain tissue in advance of trunk neurogenesis, which occurs on a much smaller scale. …”
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Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough. by Sara Hosseini-Farahabadi, Alireza Baradaran-Heravi, Carla Zimmerman, Kunho Choi, Stephane Flibotte, Michel Roberge

“…Some aminoglycosides that bind to the ribosome decoding center can induce PTC readthrough and restore low levels of full-length functional proteins. However, concomitant inhibition of protein synthesis limits the extent of PTC readthrough that can be achieved by aminoglycosides like G418. …”
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A Viscoelastic-Plastic Creep Model for Initial Damaged Coal Sample Affected by Loading Rate by Peng Huang, Yimei Wei, Meng Li, Erkan Topal, Xinyong Teng, Wei Wang

“…Based on experimental data, an integer-order viscoelastic-plastic creep model incorporating stress-dependent viscosity coefficients and damage correlation functions was developed, fully characterizing four behaviors stages: instantaneous deformation, deceleration, steady-state, and accelerated creep. …”
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The structure and predictive value of intrinsic capacity in a longitudinal study of ageing by John R Beard, A T Jotheeswaran, Matteo Cesari, Islene Araujo de Carvalho

“…More of the indirect effect of personal characteristics on incident loss of ADLs and IADLs was mediated by intrinsic capacity than multimorbidity.Conclusions The WHO construct of intrinsic capacity appears to provide valuable predictive information on an individual’s subsequent functioning, even after accounting for the number of multimorbidities. …”
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A durability- based design approach for structural applications with advanced cement-based materials by Francesco Soave, Liberato Ferrara

“…The first design phase involved the use of the prescriptive approach for ordinary reinforced concrete. The effectiveness of this design has been evaluated through the study of the effects determined by the degradation phenomena. …”
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Physical vulnerability of masonry building to the slow-moving landslide: insight from numerical simulation by Haojie Wang, Haojie Wang, Haojie Wang, Jiarui Mao, Jiarui Mao

“…Weibull functions were employed to fit vulnerability curves for masonry structures under four ground crack scenarios, revealing displacement thresholds of 22 cm, 26 cm, 27 cm, and 37 cm for complete structural vulnerability (V = 1) in each respective scenario. …”
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A database to initiate methodological advances in the evaluation of transitivity assumption in network meta-analysis: qualitative features and limitations of the tracenma R package by Loukia M. Spineli, Andrés Mauricio García-Sierra, Juan Jose Yepes-Nuñez

“…The database is hosted in the tracenma R package with functions that facilitate data access.…”
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Improving Control in the Digital Environment in the Field of Public Administration on the Example of the Republic of Mordovia by O.  V. Shibileva, V.  V. Parshutkina

“…The practical significance of the results lies in the theoretical justification of the need to improve control in the field of public administration, which provides the controllers (auditors) with the possibility of remote work with information about the functioning of facilities and obtaining detailed data. …”
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Anterior cervical discectomy with arthroplasty versus arthrodesis for single-level cervical spondylosis: a systematic review and meta-analysis. by Aria Fallah, Elie A Akl, Shanil Ebrahim, George M Ibrahim, Alireza Mansouri, Clary J Foote, Yuqing Zhang, Michael G Fehlings

“…<h4>Objective</h4>To estimate the effectiveness of anterior cervical discectomy with arthroplasty (ACDA) compared to anterior cervical discectomy with fusion (ACDF) for patient-important outcomes for single-level cervical spondylosis.…”
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Microplastics as an Emerging Potential Threat: Toxicity, Life Cycle Assessment, and Management by Sameh S. Ali, Mohammed Hussein M. Alsharbaty, Rania Al-Tohamy, Maha A. Khalil, Michael Schagerl, Majid Al-Zahrani, Jianzhong Sun

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Cuproptosis-related gene ACAD8 inhibits the metastatic ability of colorectal cancer by inducing cuproptosis by HuiE Zhuang, Yizhen Chen, Yizhen Chen, Sifu Huang

“…CuCl2 inhibited the proliferation, stemness, and migratory abilities of CRC cells, while si ACAD8 attenuated these effects. Moreover, CuCl2 enhanced the sensitivity of CRC cells to oxaliplatin and 5-fluorouracil, whereas si ACAD8 diminished this chemosensitizing effect.ConclusionAs a novel tumor suppressor, low expression of CRGs-ACAD8 is associated with the metastasis of CRC. …”
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Impact of intermittent fasting versus vitamin D on high fat fructose-induced pancreatic steatosis: possible role of aquaporins by Basma Adel Khattab, Maha Osman Hammad, Zienab Helmy Eldken, Doaa Hellal, Sherin Zohdy Mohamed, Noha Hammad Sakr

“…All these parameters improved with ADF and vitamin D supplementation, with more favorable effects for ADF. Conclusion ADF and vitamin D treatment ameliorated the effect of the high-fat fructose diet at both levels of the biochemical and histopathological examinations.…”
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Optimization of Illuminance and Color-Temperature Conditions for Railway Passengers’ Comfort Based on Oxygenated Hemoglobin Saturation in the Brain by Minkyeong Kim, Jooyeon Lee, Yonghee Lee, Duckshin Park

“…We used functional near-infrared spectroscopy to measure prefrontal cortex activation in 29 college students under illuminance values of 300, 500, and 800 lx and color-temperature values of 2700 K (bulb color), 4000 K (white color), and 5500 K (blue color). …”
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Power Grid Primary Frequency Control Strategy Based on Fuzzy Adaptive and State-of-Charge Self-Recovery of Flywheel–Battery Hybrid Energy Storage System by Shaobo Wen, Yipeng Gong, Zhendong Zhao, Xiufeng Mu, Sufang Zhao

“…Fuzzy control and regression functions were employed to adjust and constrain the frequency deviation, frequency deviation rate, and SOC. …”
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Physical properties of Alaska pollock surimi gel as affected by emulsified level and heating rates by Van-Thi Nguyen, Emiko Okazaki

“…Recently, there has been increased concern about adding fish oil to surimi to enhance its functionality in products derived from it. Our previous study showed that emulsification somewhat improves surimi’s gel-formation capacity. …”
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The Application of Entropy in Motor Imagery Paradigms of Brain–Computer Interfaces by Chengzhen Wu, Bo Yao, Xin Zhang, Ting Li, Jinhai Wang, Jiangbo Pu

“…It summarizes the names, functions, and application scopes of 13 commonly used entropy measures. …”
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STRUCTURAL CHANGES OF THE PULMONARY ARTERIES AFTER BALLOON PULMONARY ANGIOPLASTY IN PATIENTS WITH CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION by S. Y. Yarovoy, N. M. Danilov, Yu. G. Matchin, I. E. Chazova

“…Aim. To assess the effect of balloon pulmonary angioplasty (BPA) on structural parameters of the pulmonary arteries in inoperable patients with chronic thromboembolic pulmonary hypertension (CTEPH).Materials and methods. …”
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A POD-Based Reduced-Dimension Method for Solution Coefficient Vectors in the Crank–Nicolson Mixed Finite Element Method for the Fourth-Order Parabolic Equation by Xiaohui Chang, Hong Li

“…The reduced-dimension method employs identical basis functions, unlike standard CNMFE methods. It significantly reduces the number of unknowns in the computations, thereby effectively decreasing computational time, while there is no loss of accuracy. …”
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Dynamics of Progesterone, TNF-α, and a Metabolite of PGF2α in Blood Plasma of Beef Cows following Embryo Transfer by M. C. Mason, J. Copeland, E. J. Cuadra, T. H. Elsasser, Y. Jung, J. Larson

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