Nanomaterials in the treatment of degenerative intellectual and developmental disabilities by Humaira Aslam, Ali Umar, Nazia Nusrat, Manel Mansour, Aman Ullah, Shehla Honey, Muhammad Jehanzeb Sohail, Mustansar Abbas, Muhammad Waseem Aslam, Misbah Ullah Khan

“…Due to their size, surface characteristics, and ability to be functionalized, these carriers can directly deliver therapeutics across what is considered one of the main barriers to central nervous system (CNS) treatment, the blood-brain barrier (BBB). …”
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Activation of sclerostin inhibits Isg20-Mediated aerobic glycolysis ameliorating renal Fibrosis: the renoprotective mechanism of hederagenin in CKD by Rang-yue Han, Rui-zhi Tan, Ling-hui Xu, Jing-yi Lin, Tong Li, Hong-wei Su, Ping Li, Peng Liu, Hui-yao Lan, Li Wang

“…Sclerostin (Sost) functions as an inhibitor of the Wnt/β-catenin signaling pathway, which is known to promote kidney cell epithelial-to-mesenchymal transition (EMT), and fibrosis in chronic kidney disease (CKD). …”
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Music interventions in 132 healthy older adults enhance cerebellar grey matter and auditory working memory, despite general brain atrophy by Damien Marie, Cécile A.H. Müller, Eckart Altenmüller, Dimitri Van De Ville, Kristin Jünemann, Daniel S. Scholz, Tillmann H.C. Krüger, Florian Worschech, Matthias Kliegel, Christopher Sinke, Clara E. James

“…Working memory, involved in cognitive functioning and daily living, is particularly affected. …”
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Intragastric administration of short chain fatty acids greatly reduces voluntary ethanol intake in rats by María Elena Quintanilla, Daniela Santapau, Eugenio Diaz, Ignacio Valenzuela Martinez, Nicolas Medina, Glauben Landskron, Antonia Dominguez, Paola Morales, David Ramírez, Marcela Hermoso, Belén Olivares, Pablo Berríos-Cárcamo, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Fernando Ezquer

“…Among the different protective molecules that could mediate this communication, short chain fatty acids (SCFAs) have emerged as attractive candidates, since these gut microbiota-derived molecules have multi-target effects that could normalize several of the functional and structural parameters altered by chronic alcohol abuse. …”
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Bionic gene delivery system activates tumor autophagy and immunosuppressive niche to sensitize anti-PD-1 treatment against STK11-mutated lung adenocarcinoma by Zhongquan Song, Qikai Wang, Hongjie Xiong, Jiang Xiao, Zihan Zhou, Tianxiang Li, Qian Sun, Liping Qiu, Yue Tan, Xiaohui Liu, Hui Jiang, Shuhua Han, Xuemei Wang

“…This work demonstrated for the first time that restoration of functional STK11 can effectively reverse ITME and boost αPD1 efficacy in NSCLC, offering a new therapeutic approach for STK11-mutated lung adenocarcinoma in clinic. …”
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Modeling Nanoelectromechanical Resonator Signals for Experimental Mass Measurements: A Total Variation Formulation by Thomas Fortin, Adrien Reynaud, Sandra Jeudy, Szu-Hsueh Lai, Vaitson Cumaku, Chantal Abergel, Sebastien Hentz, Christophe Masselon

“…In a previous report, we thus proposed a model to remove colored noise affecting NEMS signals: Through a total variation formulation, noisy NEMS signals are “projected” onto the space of piecewise constant functions, to which non-noisy NEMS signals should theoretically belong. …”
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Multiple dimensions of the quality of life among Asian American breast cancer survivors: The impact of a technology-based program by Eun-Ok Im, Wonshik Chee, Sudeshna Paul, Seo Yun Kim, Mi-Young Choi, Jun J. Mao, Giang T. Nguyen, Marilyn M. Schapira, Connie M. Ulrich, SeonAe Yeo, Janet A. Deatrick, Jillian Inouye, Grace Ma, Salimah Meghani, David Shin, Ting Bao

“…Multiple instruments including the Functional Assessment of Cancer Therapy Scale-Breast Cancer (FACT-B) were used to assess background factors, disease factors, and the quality of life. …”
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Bringing a health systems modelling approach to complex evaluations: multicountry applications in HIV, TB and malaria by Adama Faye, Stephen S Lim, Bernardo Hernandez Prado, Herbert Duber, David E Phillips, Guillermo Ambrosio, Audrey Batzel, Carmen Cerezo, Ibrahima Gaye, Bethany Huntley, Edgar Kestler, Constant Kingongo, Emily Linebarger, Jorge Matute, Godefroid Mpanya, Salva Mulongo, Caitlin O'Brien-Carelli, Erin Palmisano, Francisco Rios Casas, Roger Tine, Daniel Whitaker, Jennifer M Ross

“…Introduction Understanding how to deliver interventions more effectively is a growing emphasis in Global Health. …”
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Exploring PDE5A upregulation in bipolar disorder: insights from single-nucleus RNA sequencing of human basal ganglia by Zhixin Bai, Peilong Li, Xu Gao, Gaoyu Zu, Andrew Jiang, Keting Wu, Naguib Mechawar, Gustavo Turecki, Klaus Lehnert, Russell G. Snell, Jin Zhou, Jia Hu, Bingbing Yan, Liang Chen, Wensheng Li, You Chen, Shuai Liu, Ying Zhu, Linya You

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Cell therapy efficacy and safety in treating tendon disorders: a systemic review of clinical studies by Seyed Peyman Mirghaderi, Zahra Valizadeh, Kimia Shadman, Thibault Lafosse, Leila Oryadi‐Zanjani, Mir Saeed Yekaninejad, Mohammad Hossein Nabian

“…The purpose of this study was to examine the potential therapeutic effects and safety of cell therapy in the treatment of tendon disorders. …”
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Toward a sustained recovery of the lodging sector: a management path to lessen the Corona Variants upshots by Ola Abdel Moneim Emara, Hazem Tawfik Halim, Mohamed Samy El-Deeb, Yasser Tawfik Halim

“…The Framework for Health Crisis Management also adds value as it amalgamates a combination of input factors of management and health enablers; a transformation via the change actions; an output of containing the effect of the pandemic through the enhanced managers’ capabilities and hotels’ health hygiene readiness; and an outcome implication of medium-term stabilizing effects that leads to an impact effect of sustained lodging sector recovery. …”
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The role of healthy wetlands in mitigating volcanic tephra impacts in Northern Patagonia by Andrea Soledad Enriquez, Manuela Fernández, Fernando Umaña, María Victoria Cremona

“…The plant growing season following the eruption generated, on average, 3929±2146 kg DM ha−1, indicating an active functional wet meadow recovery despite a 25-20% reduction in ANPP due to the tephra effect. …”
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Association of weekend catch-up sleep ratio with depressive risk: insights from NHANES 2021–2023 by Shilin Sun, Min Liu, Han Liu, Runzhou Li, Qun Liang, Weiwei Quan

“…It significantly impacts quality of life and social functioning, posing a major public health challenge. …”
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Inhibition of the FEN1-PBX1 axis elicits cellular senescence in breast cancer via the increased intracellular reactive oxygen species levels by Min Wu, Benmeng Wu, Xiaoshan Huang, Zirui Wang, Miaolin Zhu, Yaqin Zhu, Lin Yu, Jingjing Liu

“…Results Functional analysis demonstrated that FEN1 suppressed both senescence and apoptosis of breast cancer cells in vitro, while in vivo experiments demonstrated moderate therapeutic effects. …”
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Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3β Pathway by Zheng S, Xie Z, Zhou Z, Wang S, Xin Y, Lin J, Cheng K, Lu T, Qi R, Guo Y

“…Furthermore, a homologous cell membrane-based PD delivery system was established to improve the biosafety and efficacy of PD in vivo.Results: Hsa-miR-1246 was upregulated by PD treatment, and functional experiments demonstrated that the miR-1246-mimic enhanced PD’s suppressive effects on NSCLC cell proliferation, colony formation, migration, and invasion, while the miR-1246-inhibitor abrogated these effects. …”
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Patient and Provider Perspectives of a Web-Based Intervention to Support Symptom Management After Radioactive Iodine Treatment for Differentiated Thyroid Cancer: Qualitative Study by Alaina L Carr, Angela M Jenkins, Jacqueline Jonklaas, Kate Gabriel, Kristen E Miller, Kristi D Graves

“… Abstract BackgroundPatients diagnosed with differentiated thyroid cancer (DTC) who receive radioactive iodine (RAI) treatment experience acute, medium, and late treatment effects. The timing and severity of these effects vary by individual; common posttreatment effects include dry mouth, salivary gland swelling, dry eyes, and nose bleeds. …”
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THE CONTENT OF INTERLEUKINS IN ORAL FLUID OF PATIENTS WITH NON-REMOVABLE METAL CERAMIC PROSTHESES by Yu. M. Hotsko, L. Ye. Lapovets

“…Currently, the most common are the metal-ceramic structures, which have the high mechanical properties and are aesthetic and functional, because they restore chewing efficiency by 85-100% and provide a high level of adaptation to them. …”
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Canopy Chlorophyll Content Inversion of Mountainous Heterogeneous Grasslands Based on the Synergy of Ground Hyperspectral and Sentinel-2 Data: A New Vegetation Index Approach by Yi Zheng, Yao Wang, Tayir Aziz, Ali Mamtimin, Yang Li, Yan Liu

“…Canopy chlorophyll content (CCC) is a key indicator for assessing the carbon sequestration capacity and material cycling efficiency of ecosystems, and its accurate retrieval holds significant importance for analyzing ecosystem functioning. Although numerous destructive and remote sensing methods have been developed to estimate CCC, the accurate estimation of CCC remains a significant challenge in mountainous regions with complex terrain and heterogeneous vegetation types. …”
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RETRACTED ARTICLE: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Sna... by Yaodong Zhu, Yanqing Liu, Yayun Qian, Xiaojun Dai, Ling Yang, Jue Chen, Shiyu Guo, Tadashi Hisamitsu

“…In the laboratory, the ethyl acetate extract of Celastrus orbiculatus (COE) displays a wide range of anticancer functions. However, the inhibition of the metastasis mechanism of COE in gastric cancer cells has not been investigated so far. …”
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Robust ferromagnetism in wafer-scale Fe3GaTe2 above room-temperature by Shuxiang Wu, Zhihao He, Minghui Gu, Lizhu Ren, Jibin Li, Bo Deng, Di Wang, Xinhao Guo, Wanjiong Li, Mingyi Chen, Yijun Chen, Meng Meng, Quanlin Ye, Bing Shen, Xinman Chen, Jiandong Guo, Guozhong Xing, Iam Keong Sou, Shuwei Li

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