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65821
Activity Expression and Property Analysis of Codon-Optimized Polyphenol Oxidase from <i>Camellia sinensis</i> in <i>Pichia pastoris</i> KM71
Published 2025-08-01“…Future research should explore the long-term stability of recombinant CsPPO and its potential applications in tea fermentation processes and functional food development.…”
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65822
The regulatory roles of RNA-binding proteins in the tumour immune microenvironment of gastrointestinal malignancies
Published 2025-12-01“…RBPs may exhibit either anti-tumour or pro-tumour functions by influencing the TIME through the modulation of mRNAs and non-coding RNAs expression, as well as post-transcriptional modifications, primarily N6-methyladenosine (m6A). …”
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65823
Good things come in small packages: The discovery of small RNAs in the smallest animal model
Published 2025-02-01“…Ambros and Ruvkun's groundbreaking work on lin-4 and lin-14 genes in C. elegans revealed that lin-4 functions as a 22-nucleotide small RNA—now known as a microRNA (miRNA)—that binds complementarily to the 3′ UTR of lin-14 mRNA, effectively inhibiting LIN-14 protein synthesis. …”
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65824
Microanatomy related biocidal activity at cellular resolution and bone reconstruction potential of PEG EGaIn nanocapsules
Published 2025-07-01“…Abstract Critical bone defects, exacerbated by infections, pose significant challenges to bone healing and homeostasis, necessitating the development of dual-functional biomimetics that combine anti-infective and reparative capabilities. …”
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65825
A Study on the Hydrophobicity and Icephobicity of Modified Cement-Based Composite Coatings for Anti-/De-Icing of Guardrail Concrete
Published 2025-06-01“…Moreover, it featured excellent icephobicity by effectively delaying the time of icing on concrete and reducing the icing mass and ice adhesion strength. …”
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65826
Oat Protein Isolate Mitigates High-Fat Diet-Induced Obesity in Rats Through Gut Microbiota, Glucose, and Lipid Control
Published 2025-06-01“…Future clinical trials are needed to further validate the efficacy of OPI as a functional food.…”
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65827
An Enhanced TimesNet-SARIMA Model for Predicting Outbound Subway Passenger Flow with Decomposition Techniques
Published 2025-03-01“…The method decomposes time series data into Intrinsic Mode Functions (IMFs) using VMD, followed by adaptive predictions for each IMF with TimesNet and SARIMA. …”
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65828
Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility
Published 2024-11-01“…These modifications are initiated by interactions with cellular heparan sulphates (HS), however, their molecular nature and functional consequences remain elusive. Combining virological assays with hydrogen/deuterium exchange mass spectrometry, and atomic force microscopy, we investigate the effect of capsid-HS binding and structural activation. …”
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65829
Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy
Published 2025-01-01“…In mouse, these dynamics are potently antagonized by a natural UHRF1 inhibitory protein STELLA, while the comparable effects of its human ortholog are insufficiently characterized, especially in cancer cells. …”
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65830
Monopotassium maleate salt stabilizes SnO2 colloid solution for efficient perovskite solar cells
Published 2025-03-01“…Herein, we report a SnO2 modification strategy by using monopotassium maleate (MPM) salt to functionalize the SnO2 nanocrystals. It is demonstrated that MPM can effectively inhibit the agglomeration of SnO2 nanocrystals, thereby improving the conductivity and electron mobility of SnO2 and passivating the defects at the buried SnO2/perovskite interface. …”
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65831
Phase engineering of H/T-Nb2O5 homojunction for enhanced lithium-ion storage
Published 2025-01-01“…Phase engineering has gained significant attention in energy-storage applications due to its ability to tailor the physicochemical properties and functionalities of electrode materials. In this study, we demonstrate the in-situ partial phase conversion of niobium pentoxide (Nb2O5), resulting in the formation of a monoclinic/orthorhombic (H/T-Nb2O5) heterophase homojunction. …”
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65832
Proinsulin Promotes Self-Renewal of a Hematopoietic Progenitor Cell Line In Vitro
Published 2017-01-01“…Overexpression of proINS was confirmed via real-time PCR and Western blotting. The functional activity of the human proINS secreted by EML cells was elucidated by analyzing the activation of insulin receptor and its downstream signaling. …”
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65833
Strategic Approaches for Co-Encapsulation of Bioactive Compounds: Technological Advances and Mechanistic Insight
Published 2025-06-01“…Co-delivery can control the release of bioactive substances and achieve synergistic effects to enhance efficacy. For this reason, co-delivery systems have emerged as a novel strategy that has attracted much attention from researchers in recent years. …”
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65834
Advanced material innovations for self-healing high-performance supercapacitors
Published 2025-02-01“… Self-healing high-performance supercapacitors represent the state-of-the-art in energy storage development, which combines long-term durability and efficiency with the self-repair functionality after mechanical or other damages. In this review, a discussion about the very basis of supercapacitor technology is presented by studying the mechanisms and materials used for making supercapacitors self-healable, among other things, based on redox-active materials. …”
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65835
Long non-coding RNAs: New biomarkers for prognosis and diagnosis of colon cancer
Published 2017-06-01“…On the basis of the results acquired in the last decade, some long non-coding RNAs are rising as biomarkers of colorectal cancer for prognosis, diagnosis, even prediction of therapeutic result, and have crucial effects in the regulation of colorectal cancer cell functions such as proliferation, invasion, apoptosis, metastasis, and drug resistant ability. …”
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65836
Exploring Uncharted Territories in a Vertical Greening System: A Systematic Literature Review of Design, Performance, and Technological Innovations for Urban Sustainability
Published 2025-03-01“…By synthesizing current knowledge and proposing future research directions, this review aims to advance VGS as a scalable and adaptable solution for urban challenges, optimizing its functionality, sustainability, and overall effectiveness in improving urban livability.…”
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65837
<i>Lacticaseibacillus rhamnosus</i> GG and <i>Lactobacillus casei</i> Shirota Growth on a Medium Enriched with Rye Protein, and Assessment of DPP-IV Inhibitory Activity
Published 2025-02-01“…Finally, rye fermentation by probiotics is a promising process for developing plant-based products with functional properties.…”
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65838
Using implementation science to develop and deploy an oncology electronic health record
Published 2025-01-01“…Furthermore, a study conducted with 27 stakeholders revealed that the perception of the oncology electronic clinical record has considerable acceptance in three critical functionalities related to the clinical process of oncology patient management. …”
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65839
Conceptual Design and Analysis of a Trans-Domain Aircraft Based on the Camber Morphing Wing
Published 2025-05-01“…Multi-functionality and high mission adaptability are important trends in the development of future aircrafts. …”
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65840
In vitro culture and genetic modification of Babesia gibsoni
Published 2024-01-01“…The establishment and development of gene editing systems for Babesia offer a powerful tool to investigate the functions of important genes in specific biological processes. …”
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