Black tea rich in polygonatum sibiricum polysaccharides inhibits osteoporosis in ovariectomized mice through immune regulation and gut microbiota suppression by Shiyu Gao, Yikang Yu, Jialu shu, Biqian Yang, Baiqiao Zhang, Jinhao Xu, Zhenwei Wang

“…CBT has been shown to functional behavioral assessments and bone microstructure, thereby effectively retarding the progression of osteoporosis. …”
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Twenty-year outcomes after repeat doses of antenatal corticosteroids prior to 32 weeks' gestation: Follow-up of a randomised clinical trial. by Robyn W May, Anthony G B Walters, Greg D Gamble, Caroline A Crowther, Stuart R Dalziel, Carl L Eagleton, Christopher J D McKinlay, Barry J Milne, Jane E Harding

“…However, this may have been too early to evaluate potential adverse effects on respiratory and other long-term outcomes. …”
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Exploring the anti-inflammatory mechanism of geniposide in rheumatoid arthritis via network pharmacology and experimental validation by Meng Huang, Jing Jiang, Yue-Jia li, Meng-Ying Jiang, Min Yang, Hui Deng, Yong-Gang Wu, Li-Juan Wu, Xiao Leng, Jian-Lin Chen, Wen-Kui Sun

“…Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects millions worldwide, characterized by joint pain, swelling, and functional impairment. Current treatments like Non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and biologics, have limitations including side effects and resistance problems, which create a need for new therapeutic strategies. …”
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NEW DIRECTION IN LOCAL THERAPY OF OSTEOARTHRITIS OF THE KNEE JOINT by Ye. S. Tsvetkova, L. N. Denisov

“…Due to the therapy, morning stiffness was evidently decreased and functional activity was increased in the main group. …”
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Carbohydrate utilization by the gut microbiome determines host health responsiveness to whole grain type and processing methods by Caroline Smith, Mallory J. Van Haute, Yibo Xian, Rafael R. Segura Munoz, Sujun Liu, Robert J. Schmaltz, Amanda E. Ramer-Tait, Devin J. Rose

“…The amplicon sequence variants (ASVs) associated with extruded and porridge diets in this in vivo study were not the same as those identified in our prior in vitro study; however, the predicted functions were highly correlated. In conclusion, mice harboring both high and low CU microbiomes responded to the whole grain diets similarly, except the high CU microbiome mice exhibited exacerbated effects due to excessive acetate production, indicating that CU by the microbiome is linked to host metabolic health outcomes. …”
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How mindfulness-based training improves stress-related health: a selective review of randomized clinical trials comparing psychological mechanisms of action by Lara M. C. Puhlmann, Lara M. C. Puhlmann, Lara M. C. Puhlmann, Veronika Engert, Veronika Engert, Veronika Engert

“…These include subjective-psychological stress and affect, and physiological stress and stress-related health markers (e.g., activity of the autonomic nervous system, the hypothalamic-pituitary-adrenal axis and proinflammatory activity), each in two different states of the stress system: acutely stressful challenges and more long-term basal functioning. In line with MAT, we find that monitoring needs to be coupled with acceptance for beneficial effects on stress-related physiological activity in states of acute challenge. …”
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m6A methylation-mediated lncRNA RNF144A-AS1 promotes hepatocellular carcinoma progression through the miR-1301-3p/RNF38 pathway by Minyu Kong, Wendong Li, Hao Li, Yifan Jing, Min Xu, Yuting He, Wenzhi Guo

“…Methods In HCC, RNF144A-AS1 expression level and its effect on prognosis were investigated by bioinformatics. …”
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Dynamics of cellular immunity indicators in the complex treatment of acute optic neuritis by D. A. Storozhilova, O. V. Kolenko, L. P. Danilova, L. P. Emanova, I. V. Vasilieva

“…Our studies showed the effectiveness of this drug in the complex treatment of optic neuritis associated with herpes infection, what is confirmed by the acceleration of inflammation relief, a more significant increase in visual functions of patients treated with Imunofan, and a lower percentage of optic nerve atrophy. …”
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Gold(III) Complexes with 2-(1-Ethylbenzyl)pyridine as Promising Antimicrobial and Antitumor Agents by Antonio Zucca, Bruna Canu, Maria I. Pilo, Sergio Stoccoro, Giacomo Senzacqua, Sara Fais, Giuseppina Pichiri, Alessandra Scano

“…Metal ions in biological systems can essentially have two roles: structural or functional. In the former, the metal ion serves to stabilize structures, especially proteins, while in the latter, the metal is involved in bio-site reactivity (essentially in metallo-enzymes). …”
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Innovative use of indigenous dadih probiotics to enhance feed intake, digestibility, growth performance, and health in heat-stressed Sapera goats by Nurzainah Ginting, Edhy Mirwandhono, Nurjama’yah Br. Ketaren, Yuan-Yu Lin

“…Supplementation with 4 cc dadih optimized performance without disrupting hematological homeostasis, while 8 cc effectively suppressed gut pathogens. These findings offer novel insights into the functional role of traditional fermented probiotics in improving resilience to heat stress and promoting sustainable small ruminant production in tropical environments.…”
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Cytotoxic and Antioxidant Properties and Profile of Active Compounds in Kale and Lupine Sprouts Supplemented with γ-Polyglutamic Acid During Sprouting by Agnieszka Galanty, Paulina Kłos, Ewelina Prochownik, Paweł Paśko, Tomasz Skalski, Robert Podsiadły, Paweł Zagrodzki

“…These results provide a foundation for developing functional foods and sustainable agricultural practices.…”
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Your brain on art, nature, and meditation: a pilot neuroimaging study by Beatrix Krause-Sorio, Sergio Becerra, Prabha Siddarth, Stacey Simmons, Taylor Kuhn, Helen Lavretsky

“…In a pilot functional magnetic resonance (fMRI) study, we explored the effect of watching digital art or nature videos compared to contemplating the universal connectedness (also known as transcendental meditation). …”
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Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway by Jiawei Zhou, Anqi Cheng, Jianqiang Guo, Yafeng Liu, Xuan Li, Maoqian Chen, Dong Hu, Jing Wu

“…Furthermore, subcutaneous tumor xenograft models in nude mice were constructed to assess the effects of PRDX2 knockdown and the PRDX2 inhibitor Conoidin A on tumor growth in vivo. …”
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Metabolomic-Based Assessment of Earthworm (<i>Eisenia fetida</i>) Exposure to Different Petroleum Fractions in Soils by Meiyu Liu, Mutian Wang, Xiaowen Fu, Fanyong Song, Fangyuan Zhou, Tianyuan Li, Jianing Wang

“…<b>Background/Objectives:</b> Petroleum contamination in soil exerts toxic effects on earthworms (<i>Eisenia fetida</i>) through non-polar narcotic mechanisms. …”
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On the Klein–Gordon bosonic fields in the Bonnor–Melvin spacetime with a cosmological constant in rainbow gravity: Bonnor–Melvin domain walls by Omar Mustafa, Abdullah Guvendi

“…Abstract We investigate the effect of rainbow gravity on Klein–Gordon (KG) bosons in the background of the magnetized Bonnor–Melvin (BM) spacetime with a cosmological constant. …”
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Berberine Reveals Anticoccidial Activity by Influencing Immune Responses in <i>Eimeria acervulina</i>-Infected Chickens by Binh T. Nguyen, Bujinlkham Altanzul, Rochelle A. Flores, Honghee Chang, Woo H. Kim, Suk Kim, Wongi Min

“…Berberine chloride is known for its various biological functions, including its anti-parasite activity. However, its impact on intestinal morphology and immune-related activity in broilers infected with <i>Eimeria</i> still remains unclear. …”
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Interventions to mitigate drug shortages in public health systems in sub-Saharan Africa: a scoping review protocol by Constance Sewani-Rusike, Busisiwe Mrara, Olubunmi Margaret Ogbodu

“…The challenges associated with drug shortages in health systems, particularly in public health facilities, and the consequent multiple adverse effects on patients and the health systems have led countries to continue to explore and implement different strategies to combat this challenge. …”
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Biotesting of titanium tetrapolyethylene glycolate in 10 molar excess on granulosa cell culture of porcine follicles by A. O. Prituzhalova, T. I. Kuzmina, T. G. Khonina, U. S. Nikulina

“…The effect of titanium tetrapolyethylene glycolate dissolved in polyethylene glycol (ratio 1:10) (abbreviated TTPEG*10PEG) on granulosa cells (GC) of the antral ovarian follicles of Sus scrofa domesticus in the dynamics of in vitro culture was assessed. …”
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Neuromodulation through brain stimulation-assisted cognitive training in patients with post-chemotherapy subjective cognitive impairment (Neuromod-PCSCI) after breast cancer: study... by Ulrike Grittner, Agnes Flöel, Sein Schmidt, Friederike Thams, Daria Antonenko, Eva-Lotta Brakemeier, Merle Rocke, Elena Knochenhauer, Anna Elisabeth Fromm, Nora Jansen, Samaneh Aziziaram, Antje Vogelgesang

“…A follow-up visit will be performed 1 month after intervention to assess possible long-term effects. In an exploratory approach, structural and functional MRI will be acquired before the intervention and at post-intervention to identify possible neural predictors for successful intervention.Ethics and dissemination Ethical approval was granted by the ethics committee of the University Medicine Greifswald (BB236/20). …”
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<i>Thymus</i> spp. Aqueous Extracts and Their Constituent Salvianolic Acid A Induce Nrf2-Dependent Cellular Antioxidant Protection Against Oxidative Stress in Caco-2 Cells by Carlos Martins-Gomes, Fernando M. Nunes, Amélia M. Silva

“…Factors such as excessive consumption of sugar-rich and fatty foods, synthetic food additives, pesticides, alcohol, and tobacco contribute to oxidative stress and disrupt intestinal homeostasis. Functional foods arise as a potential tool to regulate redox balance in the intestinal tract. …”
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