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65521
Using digital game-based technologies in a system of studying russian as aforeign language in modern university
Published 2017-07-01“…The aggregated results of the game application will be used to evaluate the effectiveness of the proposed technology of teaching Russian as a foreign language and to develop the next levels of the game.…”
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65522
Utilizing Multi-omics analysis to elucidate the role of mitochondrial gene defects in Gastric cancer progression.
Published 2025-01-01“…Additionally, our single-cell analysis identified DUSP1 as a key mitophagy-related gene. Functional studies demonstrated that DUSP1 knockdown significantly inhibits GC cell proliferation and migration.…”
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65523
FEATURES OF THE PREVENTION OF CARIES OF TEMPORARY TEETH IN CHILDREN IN THE MOUNTAIN REGIONS OF THE TRANSCARPATHIAN REGION
Published 2022-09-01“…At the same time, the role of microand macroelements plays an important role for the full functioning of all organs and systems. The stability of the body's chemical composition is one of the most important and mandatory conditions for its normal functioning. …”
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65524
Treatment of uterine fibroid: focus on endometrial receptivity. A pilot randomized prospective study
Published 2024-12-01“…Aim. To evaluate the effect of hormonal therapy of symptomatic UF on the endometrium morphological and functional features and receptivity in patients of reproductive age. …”
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65525
Penentuan Filterbank Wavelet Menggunakan Algoritma Mean Best Basis untuk Ekstraksi Ciri Sinyal Suara Ber-Noise
Published 2020-02-01“…Each of them is the result of applying the daubechies db44 and db45 functions. Noise has no effect on the establishment of both the WPCC filterbanks. …”
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65526
Bivariate GWAS performed on rabbits divergently selected for intramuscular fat content reveals pleiotropic genomic regions and genes related to meat and carcass quality traits
Published 2025-07-01“…No allele variants were found to segregate differently between the lines in this region; however, it remains a promising region for future functional studies. Conclusions Our results showed that bivariate models assuming pleiotropic effects are valuable tools to identify genomic regions simultaneously associated with IMF and several weight, fat and meat quality traits. …”
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65527
Dual-Oriented Targeted Nanostructured SERS Label-Free Immunosensor for Detection, Quantification, and Analysis of Breast Cancer Biomarker Concentrations in Blood Serum
Published 2025-07-01“…Each stage of sensor functionalization, conjugation, and biomarker interaction was verified by UV–Vis spectroscopy. …”
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65528
Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of <i>Ganoderma lucidum</i>
Published 2025-01-01“…These compounds have various pharmacological functions, including anti-tumor, antioxidant, anti-inflammatory, liver-protective, and immune-regulating effects. …”
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65529
HR Perspectives of Russian Universities: Who Will Teach in the Near Future?
Published 2019-09-01“…A university professor is the major actor of the preparation of future specialists, the carrier of significant amount of implicit knowledge, which due to objective reasons cannot be formalised. For the full functioning of the higher school and its development, it is necessary to form and support the affective system of uninterruptable reproduction of qualified scientific and pedagogical personnel. …”
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65530
Optimized expression of oxazolomycins in engineered Streptomyces longshengensis and their activity evaluation
Published 2025-05-01“…Oxazolomycins are a unique family of polyketide-polypeptide antibiotics from Streptomyces with diverse functional groups in their structures, conferring them multifarious activities. …”
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65531
An Integrated Platform Combining Immersive Virtual Reality and Physiological Sensors for Systematic and Individualized Assessment of Stress Response (bWell): Design and Implementat...
Published 2025-03-01“…Specifically, we aimed to design various VR stress exercises based on neurocardiac models to systematically test cardiac functioning within specific contexts of self-regulation (executive functioning, physical efforts, and emotional regulation). …”
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65532
Adipose Factor ANGPTL4: Its Role in Aging Mechanisms and Associated Diseases
Published 2025-06-01“…However, the intricate and sometimes conflicting functions of the two cleavage fragments of ANGPTL4, namely N-terminal fragment (nANGPTL4) and C-terminal fragment (cANGPTL4), in different chronic diseases—exerting inhibitory or stimulatory effects depending on the disease stage—have posed challenges to the progress of ANGPTL4 antibody therapy. …”
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65533
Some aspects of morphogenesis of diabetic encephalopathy
Published 2013-08-01“…Despite great number of works on complications of diabetes mellitus of types I and II, abnormalities of cognitive functions of central nervous system are less studied. …”
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65534
Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy
Published 2021-09-01“…Purpose of the study. To study functional changes in the neuropsychological status of reproductive age patients with newly diagnosed breast cancer and to assess the possibility of using xenon-oxygen therapy to correct disorders.Patients and methods. …”
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65535
Homeostasis Changes of Tear-Producing System with the Background of Cosmetic Procedures in Periorbital Area
Published 2019-01-01“…Purpose: to conduct a comprehensive assessment of clinical and functional parameters characterizing the state of the ocular surface and the tear-producing system in case applying cosmetic procedures in the periorbital area (Botox injections, eyelid tattooing, eyelash extension). …”
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65536
QUADRUPLE HELIX IN POLICY DESIGN: RETHINKING INDUSTRIAL REVITALIZATION IN TRANSITIONAL ECONOMIES
Published 2025-06-01“…The QH model offers a powerful normative and functional framework, offering a foundation for inclusive, democratic, and resilient policy co-creation processes that can genuinely address these underlying systemic weaknesses. …”
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65537
AI in dermatology: a comprehensive review into skin cancer detection
Published 2024-12-01“…This study systematically reviews current AI applications in skin cancer classification, providing a comprehensive overview of their advantages, challenges, methodologies, and functionalities. Methodology In this study, we conducted a comprehensive analysis of artificial intelligence (AI) applications in the classification of skin cancer. …”
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65538
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.
Published 2010-06-01“…In the absence of direct biological support for identified genes, we highlighted the efficiency of subsequent functional characterization using publicly available expression profiling relevant to the skeletal system in cellular or whole animal models to prioritize candidate genes for further functional validation.…”
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65539
Association between rapid and sustained remission and clinician- and patient-reported outcomes in patients with rheumatoid arthritis: post hoc analysis of data from the SELECT-COMP...
Published 2025-06-01“…This study assessed the effect of achieving rapid remission, time to remission, and time in sustained remission on CRO/PROs. …”
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65540
Nanoparticles from grape seed extract inhibit inflammatory cytokines and ameliorate CCl4-induced hepatotoxicity
Published 2025-07-01“…Abstract Background Xenobiotic-induced liver injury is a clinically reverent condition which may influence the development of steatohepatitis via affecting numerous pathways such as oxidative stress, inflammation, mitochondorial functioning and fatty acid biosynthesis. The current study was conducted to survey the antioxidant effect of grape seeds extract nanoparticles (GS extract NPs) against CCl4-induced oxidative stress, hepatic dysfunction and inflammatory changes. …”
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