Leveraging large language models for automated detection of velopharyngeal dysfunction in patients with cleft palate by Myranda Uselton Shirk, Catherine Dang, Jaewoo Cho, Hanlin Chen, Lily Hofstetter, Jack Bijur, Claiborne Lucas, Andrew James, Ricardo-Torres Guzman, Andrea Hiller, Noah Alter, Amy Stone, Maria Powell, Matthew E. Pontell, Matthew E. Pontell

“…BackgroundHypernasality, a hallmark of velopharyngeal insufficiency (VPI), is a speech disorder with significant psychosocial and functional implications. Conventional diagnostic methods rely heavily on specialized expertise and equipment, posing challenges in resource-limited settings. …”
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Construction and optimization of a versatile bioFET platform for detecting nucleic acids and protein using the biotin–neutravidin affinity system by Jiunn-Tyng Yeh, Lian-Chin Wang, Chi-Pei Weng, Chang-Fu Kuo

“…The bioFET was constructed using an extended-gate field-effect transistor (EGFET) with an aluminum gate functionalized with (3-aminopropyl)triethoxysilane (APTES)–biotin–neutravidin. …”
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Velocity Structure Correlations between the Nebular, Molecular, and Atmospheric Gases in the Cores of Four Cool Core Clusters by Muzi Li, B.R. McNamara, Alison L. Coil, Marie-Joëlle Gingras, Fabrizio Brighenti, H.R. Russell, Prathamesh D. Tamhaneh, S. Peng Oh, Serena Perrotta

“…We explore substantial systematic biases, including projection effects, windowing, and smoothing effects, when comparing VSFs using different telescopes and instruments.…”
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Antioxidant, Phytochemical, and Pharmacological Properties of Algerian <i>Mentha aquatica</i> Extracts by Radhia Aitfella Lahlou, Ana Carolina Gonçalves, Mustapha Bounechada, Ana R. Nunes, Pedro Soeiro, Gilberto Alves, Diego A. Moreno, Cristina Garcia-Viguera, Cesar Raposo, Samuel Silvestre, Jesus M. Rodilla, Maria Isabel Ismael, Luís R. Silva

“…Water mint (<i>Mentha aquatica</i>) is used in many formulations worldwide as a functional food and natural remedy to treat gastrointestinal disorders, lung diseases, and certain mental disorders such as epilepsy and depression. …”
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Different Flooding Conditions Affected Microbial Diversity in Riparian Zone of Huihe Wetland by Bademu Qiqige, Jingjing Liu, Ming Li, Xiaosheng Hu, Weiwei Guo, Ping Wang, Yi Ding, Qiuying Zhi, Yuxuan Wu, Xiao Guan, Junsheng Li

“…The soil microbiome plays an important role in wetland ecosystem services and functions. However, the impact of soil hydrological conditions on wetland microorganisms is not well understood. …”
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Increased Homotopic Connectivity in the Prefrontal Cortex Modulated by Olanzapine Predicts Therapeutic Efficacy in Patients with Schizophrenia by Xiaoxiao Shan, Rongyuan Liao, Yangpan Ou, Yudan Ding, Feng Liu, Jindong Chen, Jingping Zhao, Yiqun He, Wenbin Guo

“…A total of 21 schizophrenic patients and 20 healthy controls were scanned by the resting-state functional magnetic resonance imaging. The patients received olanzapine treatment and were scanned at two time points. …”
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Overexpression in Plasmodium falciparum of an intrinsically disordered protein segment of PfUT impairs the parasite’s proteostasis and reduces its growth rate by Yunuen Avalos-Padilla, Yunuen Avalos-Padilla, Inés Bouzón-Arnáiz, Inés Bouzón-Arnáiz, Miriam Ramírez, Claudia Camarero-Hoyos, Claudia Camarero-Hoyos, Claudia Camarero-Hoyos, Marc Orozco-Quer, Elsa M. Arce, Diego Muñoz-Torrero, Diego Muñoz-Torrero, Xavier Fernàndez-Busquets, Xavier Fernàndez-Busquets, Xavier Fernàndez-Busquets

“…While this poses challenges for the parasite, the propensity for protein aggregation may also serve functional roles, such as stress adaptation, and could therefore be exploited by targeting it as a potential vulnerable spot in the pathogen. …”
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KIAA1199 (CEMIP) regulates adipogenesis and whole-body energy metabolism by Li Chen, Kaikai Shi, Nicholas Ditzel, Weimin Qiu, Michaela Tencerova, Louise Himmelstrup Dreyer Nielsen, Florence Figeac, Alexander Rauch, Yuhang Liu, Jiuyuan Tao, Veronika Sramkova, Lenka Rossmeislova, Greet Kerckhofs, Tatjana N. Parac-Vogt, Sébastien de Bournonville, Thomas Levin Andersen, Mikael Rydén, Moustapha Kassem

“…Mechanistically, KIAA1199 mediates its effects on adipogenesis through modulating osteopontin-integrin and AKT / ERK signaling. …”
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From Genes to Healing: The Protective Mechanisms of <i>Poria cocos</i> Polysaccharide in Endometrial Health by Yongxi Huang, Pupu Yan, Jun Zhu, Yinuo Gong, Man Liu, Haishan Cheng, Tilin Yi, Fuxian Zhang, Xiaolin Yang, Yingbing Su, Liwei Guo

“…The aim of this study is to investigate the therapeutic effect of <i>Poria cocos</i> polysaccharide (PCP) on bovine endometritis. …”
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AMPK phosphosite profiling by label-free mass spectrometry reveals a multitude of mTORC1-regulated substrates by William J. Smiles, Ashley J. Ovens, Dingyi Yu, Naomi X. Y. Ling, Andrea C. Poblete Goycoolea, Kaitlin R. Morrison, Emmanuel O. Murphy, Astrid Glaser, Sophie F. Monks O’Byrne, Scott Taylor, Alistair M. Chalk, Carl R. Walkley, Luke M. McAloon, John W. Scott, Bruce E. Kemp, Ashfaqul Hoque, Christopher G. Langendorf, Janni Petersen, Sandra Galic, Jonathan S. Oakhill

“…Whether AMPK contains other functional mTORC1 substrates is unknown. Using mass spectrometry, we generated precise stoichiometry profiles of phosphorylation sites across all twelve AMPK complexes expressed in proliferating human cells and identified seven sites displaying sensitivity to pharmacological mTORC1 inhibition. …”
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Extensive modulation of the circulating blood proteome by hormonal contraceptive use across two population studies by Nikola Dordevic, Clemens Dierks, Essi Hantikainen, Vadim Farztdinov, Fatma Amari, Vinicius Verri Hernandes, Alessandro De Grandi, Francisco S. Domingues, Orr Shomroni, Kathrin Textoris-Taube, Vivien Bahr, Hannah Schmid, Ilja Demuth, Florian Kurth, Michael Mülleder, Peter Paul Pramstaller, Johannes Rainer, Markus Ralser

“…Methods Utilizing high-throughput mass spectrometry, we quantified 148 highly abundant proteins, functioning in the innate and adaptive immune system, coagulation and nutrient transport in 3632 blood plasma, and 500 serum samples from the CHRIS and BASE-II cross-sectional population studies, respectively. …”
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A comparative analysis of single-step and multi-step methods for producing magnetic activated carbon from palm kernel shells: Adsorption of methyl orange dye by Waluyo Joko, Rahmawati Farida Dwi, Izzulhaq Muhammad Ghozy, Purba Ibnu Tryansar, Kaavessina Mujtahid, Wibowo Wusana Agung, Pranolo Sunu Herwi, Buwono Haris Puspito, Septian Ardie, Adnan Muflih Arisa

“…Iron compound inclusion aims to enhance the effectiveness of activated carbon as an adsorbent for liquid waste. …”
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P4HA2 promotes proliferation, invasion, and metastasis through regulation of the PI3K/AKT signaling pathway in oral squamous cell carcinoma by Zengpeng Chi, Qimin Wang, Xin Wang, Dagang Li, Lei Tong, Yu Shi, Fang Yang, Qingyuan Guo, Jiawei Zheng, Zhenggang Chen

“…This study focused on investigating the expression patterns, carcinogenic functions, and underlying mechanisms of P4HA2 in OSCC cells. …”
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Exploring the relationship between the androgen receptor and structural configuration of benzophenones: a combination of computational analysis and laboratory models by Da-Hyun Jeong, Rajesh Kumar Pathak, Da-Woon Jung, Jun-Mo Kim, Hee-Seok Lee

“…Key interactions with residues, such as Gln711 and Asn705, were identified. Density functional theory analysis revealed that BP-2 has a balanced energy gap, which contributes to its stability and reactivity. …”
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Metric-Based Few-Shot Learning With Triplet Selection for Adaptive GNSS Interference Classification by Felix Ott, Lucas Heublein, Tobias Feigl, Alexander Rugamer, Christopher Mutschler

“…We employ pairwise learning techniques, including triplet and quadruplet loss functions, during the training process to enhance the latent representation. …”
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Nonylphenol Removal from Water and Wastewater with Alginate-Activated Carbon Beads by Angelica A. Chacon, Elizabeth Noriega Landa, Sheng Yin, Ahsan Habib, Kiana L. Holbrook, Luis R. Duran Bojorquez, Sabur Badmos, Dino Villagrán, Wen-Yee Lee

“…The surface characterization, functional groups, and adsorption behavior were analyzed using multiple analytical techniques. …”
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Sex-Specific Inflammatory Profiles Affect Neuropsychiatric Issues in COVID-19 Survivors by Mariagrazia Palladini, Mario Gennaro Mazza, Beatrice Bravi, Margherita Bessi, Maria Cristina Lorenzi, Sara Spadini, Rebecca De Lorenzo, Patrizia Rovere-Querini, Roberto Furlan, Francesco Benedetti

“…Conversely, in males, inflammation was inversely associated with depression severity, with protective effects from regulatory mediators (IL-2, IL-4, IL-6, IL-15, LIF, TNF-α, β-NGF) against depression. …”
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Unveiling the mechanism of micro-and-nano plastic phytotoxicity on terrestrial plants: A comprehensive review of omics approaches by Asad Jamil, Ambreen Ahmad, Muhammad Moeen-ud-din, Yihao Zhang, Yuxuan Zhao, Xiaochen Chen, Xiaoyu Cui, Yindong Tong, Xianhua Liu

“…The effects of MNPs are complex and influenced by various factors including size, shape, functional groups, and concentration. …”
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Bone marrow mesenchymal stem cells senescence induced by LCCP through activation of cGAS-STING-mediated inflammation by Xiao Xiao, Song Wang, Xin Zhang, Junyong Zheng, Dazhi Yang, Songlin Peng

“…Bone marrow mesenchymal stem cells (MSCs) are a type of multipotent stem cell with self-renewal, immunoregulatory, and tissue repair capabilities, exhibiting important biological functions. In this study, MSCs were used as a model to evaluate the toxicological effects of LCCP. …”
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DNAzyme hydrogels specifically inhibit the NLRP3 pathway to prevent radiation-induced skin injury in mice by Daijun Zhou, Zhihui Li, Linbo Bao, Xiang Zhao, Jie Hao, Chuan Xu, Feifan Sun, Dan He, Chaoyang Jiang, Tian Zeng, Dong Li

“…Our previous publications have consistently demonstrated the effectiveness of biomaterials and hydrogels in preventing RISI. …”
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