The PODNL1/AKT/β-catenin signaling axis mediates glioma progression and sensitivity to temozolomide by Shanqiang Qu, Chengying Huang, Zhicheng Hu

“…Our findings revealed that both PODNL1 mRNA and protein levels were markedly upregulated in glioma tissues, and high PODNL1 mRNA level was significantly associated with poor prognosis of glioma patients. In functional assays, PODNL1 knockdown significantly suppressed the proliferation and invasion abilities of glioma cells, while overexpression of PODNL1 had the opposite effect both in vitro and in vivo. …”
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KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice. by Lara Waldschmidt, Vera Junkereit, Robert Bähring

“…We found in both sexes a KChIP2 gene dosage effect (i.e., a proportionality between number of alleles and phenotype) on Ito magnitude, however, concerning other Ito properties, KChIP2+/- resembled KChIP2+/+. …”
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The evidence for the benefits from breast milk in the neurodevelopment of premature babies – a review of the recent literature by Danuta Iulia Paduraru

“…It is known that cerebral white matter connectivity is important for later intact cognitive functioning amongst children born very preterm and that breast milk imparts neurotrophic factors. …”
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The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach by Tejpal Yadav, Hemant Kumar Singh Yadav, Abhay Raizaday, Md Sabir Alam

“…Exploring and understanding phytochemicals' functions will allow for more site-specific psoriasis treatment techniques. …”
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Dynamic Response and Computational Modeling of Truss-Reinforced Phosphogypsum-Concrete Composite Slabs Subjected to Impact Loading: A Parametric Finite Element Analysis by Lirong Sha, Yan Han, Lijie Zhang

“…Notably, PG addition effectively suppressed crack propagation, transitioning failure modes from radial fracture patterns to localized mid-span damage. …”
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Food Security–Renewable Energy Nexus: Innovations and Shocks in Saudi Arabia by Nourah A. Althani, Raga M. Elzaki, Fahad Alzahrani

“…This study aims to investigate the impacts and shocks of renewable energy consumption, particularly solar and wind energy, on food availability and stability in Saudi Arabia, by assessing both short-term and long-term effects. We use the time series annual data covering the period (2000–2022) analyzed by applying the Vector Autoregressive (VAR) model system and its environment, Granger causality, the forecast-error variance decompositions (FEVD), and the impulse response functions (IRFs). …”
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Evaluation of condensation silicone dental impression materials modified with diatomaceous Earth and zinc oxide fillers by Mohsen Fakoori, Saeed Hesaraki, Nader Nezafati, Majid ghiass

“…Results show distinct filler roles: ZnO improves functional properties (stability, antibacterial) and DE modifies surface characteristics (wettability), highlighting potential for targeted property tailoring through filler choice.…”
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Fostering positive affective exercise experiences and affect-related competencies for a physically active lifestyle: The FEEL Project – Results of the Pilot-Study by Martin Robert Bührer, Stephanie Rosenstiel, Gorden Sudeck, Julia Schmid

“…Results The primary outcome, affect regulation competence, showed a large effect from pre- to post-measurements, while affective exercise experiences demonstrated medium to large effects. …”
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Human bodies in virtual worlds: a systematic review of implicit sense of agency and ownership measured in immersive virtual reality environments by Matteo Girondini, Matteo Girondini, Marika Mariano, Marika Mariano, Giulia Stanco, Giulia Stanco, Alberto Gallace, Alberto Gallace, Laura Zapparoli, Laura Zapparoli

“…Ownership manipulations influenced implicit SoO to different extents: spatial congruence and stimulation congruence exerted moderate effects, while physical congruence showed mild effects. …”
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Ecological distribution of antibiotic resistance of soil bacteria in Zhejiang Province by XU Qiutong, CHANG Yuechang, ZHANG Mingkui

“…Here, antibiotics can have effects on the functional and structure composition of the soil microbial community and its activity, and it may increase the abundance and transfer ability of antibiotic resistance genes. …”
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Systemic organoprotection with inhaled nitric oxide (literature review) by I. A. Mandel, A. G. Yavorovsky, M. A. Vyzhigina, P. V. Nogtev, E. Yu. Khalikova, D. S. Kozlova, A. V. Bayrashevskaya, K. A. Temirova, T. A. Demura, E. N. Zolotova

“…This review describes possible ways of implementing the organоprotective effect of NO, however, the exact mechanism remains not fully understood. …”
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Citric acid vapor-assisted crosslinking of zein/PEG composite nanofiber membrane embedded with nisin by electrospinning for the cooled goose meat preservation by Lanlan Wei, Shuaijie Zhu, Guoyuan Xiong, Jingjun Li, Wangang Zhang

“…These results point to the possibility of using functionalized nanofiber membranes for the cold fresh goose meat preservation facilitated by vaporized citric acid cross-linking.…”
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Biombalance™, an Oligomeric Procyanidins-Enriched Grape Seed Extract, Prevents Inflammation and Microbiota Dysbiosis in a Mice Colitis Model by Mohamed Mokrani, Naima Saad, Ludivine Nardy, Elodie Sifré, Julie Despres, Amandine Brochot, Christine Varon, Maria C. Urdaci

“…This study investigated the effects of Biombalance™ (BB) in dextran sulphate sodium (DSS)-induced colitis in mice. …”
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TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis by Zeping He, Desheng Chen, Lei Li, Shanbao Li, Fangbin Song, Jinfeng Cai, Xueyan Guo, Yaohao Luo, Xinshuai Wang, Zeping Chen, Junming Xu

“…RNA sequencing data, somatic mutation profiles, and clinical characteristics were analyzed from TCGA, GEO, and TIMER databases. The effects of TTLL4 on cell proliferation, migration, and apoptosis were studied using functional assays and flow cytometry. …”
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Silencing of SCEL promotes progression of oral squamous cell carcinoma via activating TGF-β/Smad pathway by Danping Li, Limei Li, Shu Wu, Jun Zhao, Haishan Zhang, Qiaoli Chen, Yingxi Mo, Liudmila Matskova, Ping Li, Xiaoying Zhou

“…Abstract Objective SCEL serves as a precursor protein for the cornified envelope (CE), and its abnormal expression has been identified in various malignancies. Despite this, the functional role and detailed mechanisms of SCEL in oral squamous cell carcinoma (OSCC) remain to be clarified. …”
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Exposure to the growth promoter tylosin elicits gut microbiota disruption and metabolic imbalance in mouse model by Hongyuhang Ni, Jing Wang, Haoze Wu, Bill Kwan-wai Chan, Kaichao Chen, Han Wang, Edward Wai-Chi Chan, Fuyong Li, Sheng Chen

“…Our findings unveil the detrimental effects of tylosin on animal gut microbiota and metabolic functions and highlight the potential health risks to wildlife and humans when released into the environment. …”
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Co-encapsulated Ce6 + CpG and biopeptide-modified liposomes for enhanced transdermal photo-immunotherapy of superficial tumors by Shaozhen Wang, Chen Yang, Yuanyuan Zhang, Yi Hu, Lan Xiao, Weiping Ding, Bensheng Qiu, Fenfen Li

“…As a topical therapeutic agent, Ce6/CpG@Lip-TD circumvents the regulatory challenges associated with the systemic delivery of nanomaterials and significantly reduces systemic side effects, holding great promise for rapid translation into clinical applications.…”
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Subacute exposure to apigenin induces changes in protein synthesis in the liver of Swiss mice by Łukasz S. Jarosz, Katarzyna Socała, Katarzyna Michalak, Kamila Bulak, Artur Ciszewski, Agnieszka Marek, Zbigniew Grądzki, Piotr Wlaź, Edyta Kowalczuk-Vasilev, Anna Rysiak

“…However, there is speculation that the use of apigenin may have a hepatotoxic effect. The aim of the experiment was to assess the effect of apigenin administered intraperitoneally to mice on the concentrations of pro- and anti-inflammatory cytokines in the liver tissue and to analyse liver weight and morphological changes in the liver parenchyma. …”
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Carotenoids from Halophilic Archaea: A Novel Approach to Improve Egg Quality and Cecal Microbiota in Laying Hens by Xufeng Dou, Guodong Zhang, Hao Tang, Xiaoxue Chen, Beibei Chen, Yuxia Mei, Haihong Jiao, Min Ren

“…Carotenoids from different sources have different structures and functions, and their dietary components benefit the health of various organisms. …”
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Novel Acylated Naringin Enhances Propionate Release and Stimulates the Growth of Flavanone-Metabolizing Bacteria in an In Vitro Batch Fermentation Model by Blanca Elizabeth Ruiz-Álvarez, José Daniel Padilla-de la Rosa, Marisela González Avila, Georgina Sandoval, Yves Desjardins

“…These preliminary results highlight the potential of SCFA-acylated flavonoids as functional dietary components to increase SCFA bioavailability and support gut health, particularly from citrus-derived co-products.…”
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