Development of a Novel KCNN4-Related ceRNA Network and Prognostic Model for Renal Clear Cell Carcinoma by Hengtao Bu, Qiang Song, Jiexiu Zhang, Yuang Wei, Bianjiang Liu

“…Small interfering RNA was employed to knock down KCNN4, and corresponding functional experiments were conducted on ccRCC cells as well. …”
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Role of anoikis-related gene RAC3 in prognosis, immune microenvironment, and contribution to malignant behavior in vitro and in vivo of bladder urothelial carcinoma by Yusong Zhou, Shiwei Huang, Bing Yang, Jing Tan, Zhun Zhang, Wei Liu

“…The immune-related functional studies manifested that the two subtypes’ immune cell expressions differed. …”
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Monocationic versus dicationic-based monomethine cyanine dyes for ultrasensitive colorimetric detection of hypochlorite ion in water by Nermeen S. Hafez, Wael A. Amer, Ehab A. Okba, Mahmoud A. S. Sakr, Hussein H. Alganzory, Sohaila M. Khalil, El-Zeiny M. Ebeid

“…The ease of cyanine oxidation was substantiated by quantum chemical studies including density functional theory (DFT) calculations, natural bond orbital (NBO) analysis, molecular electrostatic potential (MESP), and time-dependent density functional theory to support the experimental results.…”
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Outcomes of intravitreal dexamethasone implant (Ozurdex®) in patients with post-surgical macular edema – a real-world scenario by Elder Ohara de Oliveira Júnior, Isabel Ahn, Rodrigo Antonio Brant Fernandes, Arthur Gustavo Fernandes

“…Conclusions Intravitreal Ozurdex implants significantly improved functional and structural aspects in post-surgical macular edema. …”
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Changing the Paradigm for Tractography Segmentation in Neurosurgery: Validation of a Streamline-Based Approach by Silvio Sarubbo, Laura Vavassori, Luca Zigiotto, Francesco Corsini, Luciano Annicchiarico, Umberto Rozzanigo, Paolo Avesani

“…Tractography enables the reconstruction of WM pathways, and bundle segmentation allows the identification of critical connections for functional preservation. This study evaluates the effectiveness of a streamline-based approach for bundle segmentation on a clinical dataset as compared to the traditional ROI-based approach. …”
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THE ROLE OF DISPOSITION OF CONNECTING TISSUE IN THE RISE OF NONTRAUMATIC SUBARACHNOIDAL HEMORRHAGE IN YOUNG AGE by E. V. Petrova, T. F. Popova, I. A. Gribacheva, G. K. Taitubayeva

“…The constitutional-anatomical and functional features, characteristic for external and internal phenotypic signs of connective tissue dysplasia in different age groups, are revealed, and the role of additional vascular risk factors in the course of SAH are found. …”
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Prebiotic potential of oligosaccharides extracted from improved Ugandan varieties of millet, sesame, soybean, and sorghum: enhancing probiotic growth and enteric pathogen inhibitio... by Docus Alowo, Solomon Olum, Ivan Muzira Mukisa, Duncan Ongeng

“…Abstract Functional gastrointestinal disorders like diarrhea continue to affect children under five years in low-income countries. …”
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Evaluation of semi prepared probiotic dessert containing phycoerythrin and Lactobacillus plantarum for period of up to two months within the refrigerator by Asma Enayatian, Seyed Amir Ali Anvar, Bahareh Nowruzi

“…Abstract The isolation of functional bioactive compounds from microalgae as sustainable sources has emerged as a new area of focus in pharmacology and functional food research. …”
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Pathogenetic Aspects of the Development and Course of Rhegmatogenous Retinal Detachment against the Background of Proliferative Vitreoretinopathy. Literature Review by J. V. Kudryavtseva, A. N. Semyonov

“…Retinal detachment (RD) is the most serious problem of modern ophthalmology, often leading to a decrease or irreversible loss of visual functions. The literature review is devoted to the latest trends in the study of the mechanisms of development and course of rhegmatogenous retinal detachment (RRD) against the background of proliferative vitreoretinopathy. …”
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INDUCED PLURIPOTENT STEM CELL-DERIVED MICROGLIA TO STUDY NLRP3 INFLAMMASOME ACTIVATION IN ALZHEIMER’S DISEASE by Aslı Erdoğan, Cira Dansokho, Jari Koıstınaho, Sarka Lehtonen, Seyhun Solakoğlu, Michael Thomas Heneka

“…The stimulation of the microglia cells with LPS and Aβ caused IL- 1beta and IL-18 release, while CRID3 reversed this effect.Conclusion: Our results show that iPSC-derived microglia generated in this study recapitulate microglia functional characteristics and can therefore be used to study NLRP3 pathway-associated disease mechanisms and treatment options.…”
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Identification of RNA binding protein genes associated with colorectal cancer by bioinformatics analysis by Rong-Chao He, Haibo Wang, Jun He, Hou-Dong Wang, Zhong Shen

“…This model effectively stratifies patients into 2 risk categories, each associated with differing survival outcomes. …”
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Identification of hub genes in myocardial infarction by bioinformatics and machine learning: insights into inflammation and immune regulation by Juan Yang, Xiang Li, Li Ma, Jun Zhang

“…These genes were then subjected to functional enrichment analysis, including Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and Gene Set Enrichment Analysis (GSEA). …”
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Comprehensive analysis of human keratinocyte interactions with Candida albicans and Candida parapsilosis by Ádám Novák, Erik Zajta, Máté Csikós, Emese Halmos, Márton Horváth, Orsolya Tildy, András Szekeres, Gergő Svorenj, Nikolett Gémes, Gábor J. Szebeni, Renáta Tóth, Attila Gácser

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Right ventricular outflow tract obstruction in twin‐to‐twin transfusion syndrome undergoing laser surgery: A systematic review and meta‐analysis by Hiba J. Mustafa, Muhammad Jawwad, Ayesha Iqbal Mansoor, Giorgio Pagani, Francesco D'Antonio, Asma Khalil

“…In all, 134/197 (68%) had functional pulmonary stenosis and 62/197 (32%) had functional pulmonary atresia. …”
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Internet use patterns and their relationship with frailty in older Japanese adults by Yaya Li, Kayo Godai, Michiko Kido, Susumu Komori, Ryoichi Shima, Kei Kamide, Mai Kabayama

“…Abstract Background Internet use is increasing among older adults worldwide, raising interest in its potential empowering effects on healthy aging. However, the relationship between internet use and frailty among older adults remains underexplored. …”
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Enhancing Efficiency and User Experience of Digital Community Health Worker Payments in Zanzibar: Implementation Report by Lee Pyne-Mercier, Krishna Jafa, Susan Maigua, Jennifer Muli, Elijah Gichinga, Antony Khaemba, Nitusima Kataraia, Aisha Mohammed, Frank Kamangadazi Tembo, Imran Esmail, Giulia V R Besana, Heiko Hornung, Ali Makame Zubeir

“…MethodsWe applied Medic’s design process to develop new functionality for the open-source Community Health Toolkit. …”
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Isolated Dipolar ONN Schiff Base Regioisomers: Synthesis, Characterization and Crystallographic Study by Pablo Castro-Tamay, David Villaman, Jean-René Hamon, Néstor Novoa

“…Organic compounds with 1,3-diketone or 3-amino enone functional groups are extremely important as they can be converted into a plethora of carbo- or heterocyclic derivatives or can be used as ligands in the formation of metal complexes. …”
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Interprofessional homebased reablement intervention for older adults in Sweden: a randomized controlled trial by Lena-Karin Gustafsson, M. Söderman, C. Johansson, M. L. Elfström

“…The goal is to enhance or maintain health and functional ability and, thereby, the ability of older adults to live in their own homes. …”
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Study protocol for a single-centre non-inferior double-blinded randomised controlled trial in China comparing the efficacy and safety of high-frequency irreversible electroporation... by Rui Chen, Bi-Ming He, Zhen-Kai Shi, Hai-Feng Wang

“…Although it has been proven to have substantial efficacy in improving functional outcomes, it has shown a high incidence of complications, including transurethral resection syndrome, massive bleeding, urinary incontinence and sexual dysfunction. …”
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Single-cell RNA sequencing technology was employed to construct a risk prediction model for genes associated with pyroptosis and ferroptosis in lung adenocarcinoma by Longfei Ji, Binyu Wang, Danfei Shi, Weiyun Shen, Xinmin Li, Yong Li

“…The seven gene prognostic model we constructed (CXCL2, SLC7A5, CAV1, IFNG, EPAS1, TNFAIP3, CYBB) can effectively distinguish high-risk LUAD patients. Functional enrichment analysis revealed that the IL-17 signaling pathway is active in high-risk populations, suggesting that apoptosis may promote the progression of LUAD through immune dysfunction. …”
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