Association of real life postural transitions kinematics with fatigue in neurodegenerative and immune diseases by Robbin Romijnders, Arash Atrsaei, Rana Zia Ur Rehman, Lea Strehlow, Jèrôme Massoud, Chloe Hinchliffe, Victoria Macrae, Kirsten Emmert, Ralf Reilmann, C. Janneke van der Woude, Geert Van Gassen, Frédéric Baribaud, Teemu Ahmaniemi, Meenakshi Chatterjee, Bruno Kusznir Vitturi, Clémence Pinaud, Jérôme Kalifa, Stefan Avey, Wan-Fai Ng, Clint Hansen, Nikolay V. Manyakov, Walter Maetzler

“…Wearable sensors, like inertial measurement units (IMUs), offer a way to monitor daily activities and evaluate functional capacity. This study investigates the relationship between sit-to-stand and stand-to-sit transitions and self-reported physical and mental fatigue in participants with Parkinson’s, Huntington’s, rheumatoid arthritis, systemic lupus erythematosus, primary Sjögren’s syndrome and inflammatory bowel disease. …”
Get full text

Simple Method for Efficient RNA Extraction From Arabidopsis Embryos by Fernanda Marchetti, Gabriela Pagnussat, Eduardo Zabaleta

“…Isolating them is crucial when endosperm and seed coat tissues interfere with the study of mutant genetic functions due to differing genotypes between maternal and embryonic tissues. …”
Get full text

Blood Cell Membrane-Coated Nanomaterials as a Versatile Biomimetic Nanoplatform for Antitumor Applications by Hanchun Shen, Yongliang Ouyang, Liang Zhang, Jing Li, Shige Wang

“…The rich diversity and multifaceted functions of blood cells offer promising biological avenues for enhancing the application of nanoparticles in cancer therapy. …”
Get full text

Experimental Study of Direct Laser Deposition of Ti-6Al-4V and Inconel 718 by Using Pulsed Parameters by Kamran Shah, Izhar Ul Haq, Shaukat Ali Shah, Farid Ullah Khan, Muhammad Tahir Khan, Sikander Khan

“…Its potential for creating multimaterial and functionally graded structures is now beginning to be explored. …”
Get full text

Tissue adaptation to metabolic stress: insights from SUMOylation by Hao Xie, Xin Liu, Shuo Li, Ming Wang, Ying Li, Ting Chen, Linwei Li, Faxi Wang, Xuan Xiao, Xuan Xiao

“…SUMOylation regulates various functions, including cell proliferation, differentiation, apoptosis, senescence, and maintenance of specific cellular activities. …”
Get full text

Recent advances on application of polysaccharides in cosmetics by Qingyuan Wu, Na Cheng, Danjiao Fang, Hao Wang, Faiz-Ur Rahman, Huifang Hao, Yongmin Zhang

“…At present, the mechanism of polysaccharide exerting cosmetic activity has been widely studied, but the relationship between polysaccharide’s chemical structure and cosmetic activity has not been effectively analyzed, which leads to the limitation of polysaccharide development. …”
Get full text

Progress of mesenchymal stem cell-derived exosomes in targeted delivery of antitumor drugs by Defa Huang, Wenlong Huang, Meijin Liu, Jie Chen, Dewang Xiao, Zongbo Peng, Haoquan He, Haibin Shen, Qing Jin, Linli Chen, Dingyu Rao, Minghong Zhao, Junyun Huang

“…Exosomes are extracellular vesicles containing a variety of components such as proteins, nucleic acids and lipids, which are widely present in biological fluids and have the functions of participating in intercellular information transfer, immune response and tissue repair, and can also be used as carriers to target and deliver tumors to improve therapeutic effects. …”
Get full text

PTEN deficiency in postnatally developing Purkinje cells disrupts metabolic signaling, leading to dendritic abnormalities and sex-specific behavioral deficits by Lindsay J. Walsh, Izabella M. Espinal-San Miguel, Ana V. Rodriguez, Ursula M. Peña, Kiley E. Flynn, Will C. Remillard, Siena R. Brazier, Natalia I. Anderson, Aidan J. Clark, Tiffany A. De Varona, Ileana Soto

“…Here, we investigated the effects of PTEN conditional deficiency on PC dendritic development and early postnatal motor, spontaneous, and social behaviors. …”
Get full text

The Structures, Spectroscopic Properties, and Photodynamic Reactions of Three [RuCl(QN)NO]− Complexes (HQN = 8-Hydroxyquinoline and Its Derivatives) as Potential NO-Donating Drugs... by Leilei Xie, Lifang Liu, Wenming Wang, Zhiou Ma, Liqun Xu, Xuan Zhao, Hongfei Wang

“…The structures and spectral properties of three ruthenium complexes with 8-hydroxyquinoline (Hhqn) and their derivatives 2-methyl-8-quinolinoline (H2mqn) and 2-chloro-8-quiolinoline (H2cqn) as ligands (QN = hqn, 2mqn, or 2cqn) were calculated with density functional theory (DFT) at the B3LYP level. The UV-Vis and IR spectra of the three [RuCl(QN)NO]− complexes were theoretically assigned via DFT calculations. …”
Get full text

Evolutionary literacy as a catalyst for sustainable futures: connecting biological evolution education and education for sustainability by Patrícia Pessoa, J. Bernardino Lopes, Joelyn de Lima, Alexandre Pinto, Peter Søgaard Jørgensen, Xana Sá-Pinto

“…Abstract In the face of growing societal, public health and environmental challenges linked to the functioning of the biosphere, strong evolutionary literacy emerges as indispensable to plan and achieve sustainable futures. …”
Get full text

Pseudo-binary reactive synthesis of porous multi-component alloys by Huibin Zhang, Xin Yan, MeiMei Zhang, LeiLei Wan, Yilin Zhang, Linping Yu, Xubin He, Huazhen Cao, Guoqu Zheng, Yuehui He

“…Porous multicomponent alloys, as pivotal functional materials, hold great promise for applications in environmental protection and energy conversion fields. …”
Get full text

Urban-Scale Rooftop Photovoltaic Potential Estimation Using Open-Source Software and Public GIS Datasets by Matej Cenky, Jozef Bendik, Peter Janiga, Illia Lazarenko

“…This paper aims to effectively estimate urban-scale rooftop photovoltaic potential using strictly open-source software and publicly available GIS data. …”
Get full text

Analysis of Stiffness and Energy Consumption of Nonlinear Elastic Joint Legged Robot by Dongliang Chen, Jindong Zhang, Xutao Weng, Yunjian Zhang, Zhonghui Shi

“…Based on the dynamic analysis, a functional relationship between the output torque and the torsion spring stiffness and between the energy consumption and the torsion spring stiffness was established. …”
Get full text

Reorganization of Synaptic Connections and Perineuronal Nets in the Deep Cerebellar Nuclei of Purkinje Cell Degeneration Mutant Mice by M. Blosa, C. Bursch, S. Weigel, M. Holzer, C. Jäger, C. Janke, R. T. Matthews, T. Arendt, M. Morawski

“…In a mouse model for Purkinje cell degeneration, we examined the effect of deafferentation on synaptic remodeling and modulation of PNs in the deep cerebellar nuclei. …”
Get full text

Imidazole Headgroup Phospholipid Shows Asymmetric Distribution in Vesicles and Zinc-Dependent Esterase Activity by Gabriela Sachet-Fernandez, James W. Hindley, Oscar Ces, Rüdiger Woscholski

“…Our data reveal a zinc-dependent esterase activity that was strongest in vesicles and micelles, with slower catalytic rates being observed in flat lipid presentation systems and two-phase systems, indicating the importance of surface presentation and curvature effects on the catalytic activity of PtdHisOH. Such lipids offer the opportunity to impart de novo catalytic functionality to self-assembled lipid systems such as synthetic cells, leading to the development of new technologies for biocatalysis applications.…”
Get full text

In vitro digestion and fecal fermentation behaviors of exopolysaccharide from Morchella esculenta and its impacts on hypoglycemic activity via PI3K/Akt signaling and gut microbiota... by Weihong Guo, Xuerui Wang, Biao Wang, Yajie Zhang, Fengyun Zhao, Yuling Qu, Liang Yao, Jianmin Yun

“…This study aimed to evaluate the effects of gastrointestinal digestion on the physicochemical properties and hypoglycemic activity of extracellular polysaccharides from Morchella esculenta (MEPS). …”
Get full text

“Why would I bother?” Understanding prosumer motivations and engagement in renewable energy communities: a qualitative study of polish photovoltaic installation owners by Maksymilian Bielecki, Ewa Neska, Anna Kowalska-Pyzalska

“…The development and efficient functioning of RECs depend not only on technical or economic factors but also on numerous socio-psychological variables deeply rooted in local historical, political, economic, and cultural contexts. …”
Get full text

Biodegradable Polymers Induce CD54 on THP-1 Cells in Skin Sensitization Test by Yeon Suk Jung, Reiko Kato, Toshie Tsuchiya

“…The human cell line activation test (h-CLAT) is a skin sensitization assessment that mimics the functions of dendritic cells (DCs). DCs are specialized antigen-presenting cells, and they interact with T cells and B cells to initiate immune responses. …”
Get full text

Review of AI Image Enhancement Techniques for In-Vehicle Vision Systems Under Adverse Weather Conditions by Tiande Mo, Siqian Zheng, Wai-Yat Chan, Renhua Yang

“…Visual perception is crucial for enhancing the functionality and safety of self-driving technology. …”
Get full text

Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging and personalized therapy by Jorge Barrios, Evan Porter, Dante P. I. Capaldi, Taman Upadhaya, William C. Chen, Julian R. Perks, Aditya Apte, Michalis Aristophanous, Eve LoCastro, Dylan Hsu, Payton H. Stone, Javier E. Villanueva-Meyer, Gilmer Valdes, Fei Jiang, Michael Maddalena, Ase Ballangrud, Kayla Prezelski, Hui Lin, Jinger Y. Sun, Muhtada A. K. Aldin, Oi Wai Chau, Benjamin Ziemer, Maasa Seaberg, Penny K. Sneed, Jean L. Nakamura, Lauren C. Boreta, Shannon E. Fogh, David R. Raleigh, Jessica Chew, Harish Vasudevan, Soonmee Cha, Christopher Hess, Ruben Fragoso, David B. Shultz, Luke Pike, Shawn L. Hervey-Jumper, Derek S. Tsang, Philip Theodosopoulos, Daniel Cooke, Stanley H. Benedict, Ke Sheng, Jan Seuntjens, Catherine Coolens, Joseph O. Deasy, Steve Braunstein, Olivier Morin

“…Leveraging this data, we propose a probabilistic brain metastasis risk model to enhance the therapeutic ratio of whole-brain radiotherapy by targeting high risk areas while preserving cortical and subcortical brain regions of functional significance and low metastasis risk, potentially reducing the cognitive side effects of therapy.…”
Get full text