Conditional Control of CRISPR/Cas9 Function by Chemically Modified Oligonucleotides by Liangliang Wang, Yan Liu, Hongjun Song, Xue Zhang, Yang Wang

“…The CRISPR (clustered regularly interspaced short palindromic repeats) system has emerged as a revolutionary gene-editing tool with immense potential in gene therapy, functional genomics, and beyond. However, achieving precise spatiotemporal control of gene editing in specific cells and tissues while effectively mitigating potential risks, such as off-target effects, remains a key challenge for its clinical translation. …”
Get full text

Impact of advanced prostatic cancer treatment on quality of life and sexual function by Fernando Parma Marsicano, Andy Petroianu

“…The adverse effects reported in the four groups following the treatments were statistically compared and significance was considered indicated by p-values of <0.05. …”
Get full text

Modelling of Functional Interaction of Hybrid Energy Storage System Battery Units by K. V. Dobrego, I. A. Koznacheev

“…From the point of view of evaluating the effectiveness of storage hybridization, a number of model systems operating under different load conditions using different block functional interaction schemes are being investigated. …”
Get full text

Wearable photonic smart wristband for cardiorespiratory function assessment and biometric identification by Wenbo Li, Yukun Long, Yingyin Yan, Kun Xiao, Zhuo Wang, Di Zheng, Arnaldo Leal-Junior, Santosh Kumar, Beatriz Ortega, Carlos Marques, Xiaoli Li, Rui Min

“…The assessment of cardiorespiratory function and biometric identification (ID) is crucial for the effectiveness of such personalized health services. …”
Get full text

Development of technology for functional products on basis of vegetable and fish raw materials by Valeria A. Potapova, Olga Ya. Mezenova

“…Rational parameters for the thermal treatment of backbones are determined. Effect of vegetable additives of Jerusalem artichoke on functional and technological properties of the minced bone systems is examined. …”
Get full text

Fear of predators alters herbivore regulation of soil microbial community function by Wei Tian, Dror Hawlena, Jordi F. Pagès, Zhiwei Zhong, Deli Wang

Get full text

Fitting Methods for Probability Distribution Functions in Turbulent Star-forming Clouds by Avery Kiihne, Sabrina M. Appel, Blakesley Burkhart, Vadim A. Semenov, Christoph Federrath

“…We use a suite of 3D simulations of star-forming molecular clouds, with and without stellar feedback and magnetic fields, to investigate the effectiveness of different fitting methods for volume and column density probability distribution functions (PDFs). …”
Get full text

Functions, mechanisms, and therapeutic implications of noncoding RNA in acute myeloid leukemia by Xiaokang Wang, Yong Tong, Tianrong Xun, Haixing Feng, Yuhe Lei, Yuanqing Li, Kit Hang Wu, Fang Qiu

Get full text

Tat-specific antibodies associated with better HIV-associated motor function by Catarina E. Hioe, Clauvis Kunkeng Yengo, Xiaomei Liu, Reuben Davis, Gospel Enyindah-Asonye, Jéromine Klingler, Alex F. Tang, Juan C. Bandres, Anuradha Ganesan, Tahaniyat Lalani, Joseph Yabes, Brian K. Agan, Xiaokun Liu, David J. Volsky, Susan Morgello, Jessica Robinson-Papp

“…This disparity was evident in plasma and cerebrospinal fluid, and was also seen in early infection, before antiretroviral therapy. When the effects of antibodies on Tat function were evaluated, PWH plasma had no activity against Tat-induced transactivation, while Tat-immunized mouse and rabbit sera exhibited a potent inhibitory activity. …”
Get full text

Preservation of ovarian endocrine function in patients with lymphoma: a systematic review by Hebatallah Ahmed Mohamed Moustafa, Al Shaimaa Ibrahim Rabie, Ahmed Abdullah Elberry, Ahmed Hassan Shaaban, Amany Mohamed Alboghdadly, Hind Khalid Goresh, Muath Fahmi Najjar, Mabrouk AL-Rasheedi, Raghda R. S. Hussein

“…Its treatment has a cytotoxic effect on all body tissues, especially female ovaries, yielding premature ovarian insufficiency. …”
Get full text

Lactic Acid Bacteria in Vinegar Fermentation: Diversity, Functionality and Health Benefits by Elahesadat Hosseini, Zenebe Tadesse Tsegay, Slim Smaoui, Theodoros Varzakas

“…These active compounds have antibacterial, antioxidant, anti-inflammatory functions; aid in the regulation of liver protection metabolism and glucose control; and have blood pressure, anti-tumor, anti-fatigue and metabolic regulatory effects. …”
Get full text

The Structural and Functional Responses of Rhizosphere Bacteria to Biodegradable Microplastics in the Presence of Biofertilizers by Xueyu Cheng, Xinyang Li, Zhonghua Cai, Zongkang Wang, Jin Zhou

“…We investigated the effects of coexisting biofertilizers and Bio-MPs on the structure, function, and especially the carbon metabolic properties of crop rhizosphere bacteria, using a pot experiment in which polyethylene microplastics (PE-MPs) were used as a reference. …”
Get full text

Functional cognitive performance augments cognitive screening data in older adults by Timothy S. Marks, Gordon Muir Giles, Dorothy Farrar Edwards

Get full text

Beyond pollination – The neglected contribution of ground-nesting bees to soil functions by Philippe Tschanz, Matthias Albrecht, Thomas Keller

“…Furthermore, we discuss the large-scale indirect effects on soils through their pollination functions, which shape plant communities and soil functions modulated by plants. …”
Get full text

High SERS performance of functionalized carbon dots in the detection of dye contaminants by Yanqiu Yang, Lingru Kong, Yong Ding, Lixin Xia, Shuo Cao, Peng Song

“…Introduction: The long-term overuse of malachite green (MG) has potential carcinogenic, teratogenic, and mutagenic effects. The functional nanocomposite is novel and challenging to construct and implement through surface enhanced Raman scattering (SERS) strategy to reveal the contributions in application. …”
Get full text

Research advances on the functions of probiotic fermented milk in regulating body health by ZHAO Cui-yu, WU Zi-jian, LI Shu-sen, LIU Ju-long, ZHANG Xin-yu, SUN Er-na, WEN Yan

“…This review expounds the auxiliary effects of probiotics fermented milk in improving intestinal function, regulating body immunity, assisting in treating metabolic diseases and improving mental system diseases, etc., in order to provide theoretical support for expanding the application of probiotics fermented milk.…”
Get full text

The program Simourg for simulating the response functions of gamma detectors with simple geometries by V. V. Kobychev

“…The program is designed for quick estimation of the effectiveness and the response function of the detector to monoenergetic gamma quanta in the energy range from kiloelectronvolts to several megaelectronvolts.…”
Get full text

A rare case of non-functional Paraganglioma of urinary bladder with No LUTS by Mohammad Poury, Mohsen Ayati, Seyed Ali Momeni, Laleh Sharifi

“…Here, we present our patient with incidental finding of non-functional paraganglioma of urinary bladder who showed no lower urinary tract symptoms (LUTS). …”
Get full text

Global Convergence for Cohen-Grossberg Neural Networks with Discontinuous Activation Functions by Yanyan Wang, Jianping Zhou

“…Finally, an example is given to illustrate the effectiveness of the obtained results.…”
Get full text

Influence of the mold inhibitor on productivity and functional activity of broiler chicken’s liver by A. A. Baeva, L. A. Vityuk, I. R. Tletseruk, N. V. Lyashenko

“…The purpose of the study was to study the effect of different doses of the Oxy-Nile mold inhibitor in rations with an increased content of B1 aflatoxin on the utility-beneficial qualities and functional activity of the liver of broiler chickens. …”
Get full text