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PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways
Published 2024-01-01“…However, the role of PU.1 in COPD and its effects on EPC function and lunghoming, remain unclear. …”
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3523
Effects of substituting soybean meal with fermented rapeseed meal mixture on the growth performance, slaughter performance, meat quality, blood biochemical indices and intestinal barrier function in Langshan Chickens
Published 2024-12-01“…This study aimed to explore the effects of substituting soybean meal with a mixture of solid-state fermented rapeseed meal, apple pomace, and wheat bran on the growth performance, slaughter performance, meat quality, blood biochemical indices and intestinal barrier function of Langshan chickens. …”
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3524
Investigating the effects of a randomized, double-blinded aerobic, resistance, and cognitive training clinical trial on neurocognitive function in older adults with cardiovascular risk factors: the ACTIONcardioRisk protocol
Published 2025-06-01“…Assessments will be administered before, half-way and after the intervention: cognition (primary outcome), cerebral imaging with a focus on cerebrovascular mechanisms (secondary outcomes), and exploratory outcomes (genetic profile, chronic stress biomarkers, metabolic function, inflammation markers, mood, sleep, and diet).DiscussionThe present design uses a 12-month intervention period to maximize the likelihood of identifying the cerebrovascular markers involved in exercise training effects on cognitive performance in individuals with CVRF. …”
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3526
Effects of Self-Assisted Manual Therapy Combined with a High-Intensity Walking Program on Musculoskeletal Pain, Functionality, and Posture in Older Adults: A Multicentre Randomized Controlled Trial
Published 2025-05-01“…Background: Aging is associated with musculoskeletal pain and postural adaptations which may affect functionality. This study aims to analyse the effect of a combined protocol of self-assisted manual therapy and high-intensity walking on musculoskeletal back pain, functionality, and shoulder posture in older adults, and to establish the short- and medium-term effects of this program. …”
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Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-controlled trial.
Published 2021-01-01“…Hyperbaric oxygenation therapy, which was shown to improve insulin sensitivity, is impractical for regular use. We evaluated the effects of water which is stably-enriched with oxygen (ELO water) to increase arterial blood oxygen levels, on mitochondrial function in the presence of normal- or high-glucose environments, and as glucose-lowering therapy in humans.…”
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3530
Associating cultivars or species with complementary traits is key for enhancing aphid control through bottom‐up effects
Published 2025-02-01“…Mixing wheat cultivars with complementary functional traits (height and odor profile) and the association of wheat monoculture with a burclover undersowing enhances aphid control by bottom‐up effects without compromising crop yield. …”
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3532
The relationship between the coarticulatory source and effect in sound change: evidence from Italo-Romance metaphony in the Lausberg area
Published 2024-06-01“…In ongoing sound changes, a coarticulatory effect is often enhanced as the coarticulatory source that gives rise to it wanes. …”
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SHORT-TERM EFFECTS OF THE COMPLEX REHABILITATION PROGRAM INCLUDING NEMEC’S CURRENTS AND THERAPEUTIC EXERCISES IN PATIENTS WITH KNEE OSTEOARTHRITIS
Published 2022-02-01“…Conclusion: The results of the study showed significant improvement in the functional activity of patients (WOMAC Index). Nemec’s medium frequency currents therapy and therapeutic exercises can effectively reduce pain (VAS), swelling, muscle weakness (MMT), and range of motion in patients (ROM) with gonarthritis. …”
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MSCs-derived ECM functionalized hydrogel regulates macrophage reprogramming for osteoarthritis treatment by improving mitochondrial function and energy metabolism
Published 2024-12-01“…In this study, we developed an ECM-functionalized hydrogel by combining MSC-derived ECM with gelatin methacryloyl (GelMA). …”
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Cyclopiazonic acid suppresses the function of Leydig cells in prepubertal male rats by disrupting mitofusin 1-mediated mitochondrial function
Published 2025-01-01“…This research investigated the impact of cyclopiazonic acid (CPA), a mycotoxin, on the function of progenitor Leydig cells (PLCs) in prepubertal male rats, focusing on its potential disruption of mitochondrial integrity through mitofusin 1 (MFN1) modulation. …”
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Functional Application of G-Functions of Lorenzo and Hartley on the Free Convection Flow of Oldroyd-B Fluid with Ordinary and Fractional Techniques
Published 2021-01-01“…Closed form solutions for the velocity and temperature profiles are obtained via Laplace coupled with sine-Fourier transforms and have been embedded with regards to the special functions, namely, the generalized G-functions of Lorenzo and Hartley. …”
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3538
Toward an innovative function-oriented assessment methodology (FOAM) for evaluating the functional condition of buildings during the operation and maintenance phase
Published 2024-12-01“…A case study validates the effectiveness of this strategic framework, demonstrating high consistency and accuracy in evaluating functional conditions. …”
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3539
The effect of tofacitinib on function and quality of life indicators in patients with rheumatoid arthritis resistant to synthetic and biological disease-modifying antirheumatic drugs in real clinical practice: Results of a multicenter observational study
Published 2017-03-01“…The results of our multicenter study using considerable Russian material confirmed the pronounced positive effect of TOFA used as a second-line agent (after s-DMARD failure) and a third-line agent (after s-DMARD and BA failure) on patients' assessment of disease activity, functional ability in daily life, and quality of life.…”
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