Vertebral Osteoporosis in Systemic Lupus Erythematosus: A Possible Involvement of Inflammation-Related Osteoblast Ferroptosis by Lao Z, Chen X, Chen X, Zhang H, Zhang Z, Bian Y, Zhou C, Tian K, Jin H, Fu F, Wu C, Gan K, Ruan H

“…This study utilized the MRL/lpr mouse model, which effectively replicates human SLE manifestations, to investigate the impact of SLE on vertebral bone homeostasis.Methods: Female MRL/lpr mice were employed to investigate SLE-induced bone loss. …”
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TMAO Induces Vascular Endothelial Cells Pyroptosis Through TET2-CYTB-ROS Pathway by Xia L, Wang Z, Chen X

“…CYTB methylation was detected using Targeted Bisulfite Sequencing.Results: This study showed that TMAO can down-regulate the expression of CYTB inVECs, cause VECs pyroptosis and mitochondrial dysfunction (MDF). CYTB overexpression antagonized the effect of TMAO. …”
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Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants by Gajalakshmi Ramanathan, Yuqi Zhao, Rajat Gupta, Siri Langmo, May Bhetraratana, Fen Yin, Will Driscoll, Jerry Ricks, Allen Louie, James A. Stewart, Timothy R. Gould, Timothy V. Larson, Joel Kaufman, Michael E. Rosenfeld, Xia Yang, Jesus A. Araujo

“…DE exposure significantly dysregulated 118 metabolites, resulting in increased levels of triglycerides and fatty acids due to mitochondrial dysfunction as well as increased levels of glucose and oligosaccharides. …”
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POSSIBILITIES OF IVABRADINE, A SELECTIVE INHIBITOR OF ION F-CHANNELS OF SINUS NODE, IN PREVENTION OF ANTHRACYCLINE CARDIOTOXICITY IN PATIENTS WITH BREAST CANCER by Yu. V. Vasyuk, V. V. Nesvetov, E. L. Shkolnik, L. D. Shkolnik, G. V. Varlan, G. E. Gendlin, E. I. Emelina

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Predicting hypotensive effect of physical training in arterial hypertension patients by N. I. Gromnatsky, V. A. Novikov, V. N. Shilenok

“…Therefore, hypotensive PT effect predictors were AH severity, IV diastolic dysfunction, unchanged MCA peripheral resistance indices, and decreased metabolic reserve of cerebral blood flow auto-regulation.…”
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A safety and feasibility randomized placebo controlled trial exploring electroencephalographic effective connectivity neurofeedback treatment for fibromyalgia by Lucy Anderson, Dirk De Ridder, Paul Glue, Ramakrishnan Mani, Cindy van Sleeuwen, Mark Smith, Divya Bharatkumar Adhia

“…This study evaluates the safety, feasibility, and acceptability of a novel electroencephalography-based neurofeedback training, targeting effective alpha-band connectivity from the pgACC to S1 and exploring its effect on pain and function. …”
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Low-carbohydrate diets reduce cardiovascular risk factor levels in patients with metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis of... by Shanshan Pi, Shanshan Pi, Shuwen Zhang, Shuwen Zhang, Junjie Zhang, Junjie Zhang, Yi Guo, Yue Li, Yue Li, Jinyan Deng, Jinyan Deng, Hongbo Du, Hongbo Du

“…Meta-analyses were performed using fixed-effects or random-effects models, as determined by the heterogeneity of the included studies. …”
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Transitioning from NAFLD to MAFLD and MASLD: the toxic relationship with alcohol consumption by Mubin Ozercan, Ahmed Tawheed, Mohamed El-Kassas

“…Recently two major liver committees adopted new terminologies such as metabolic-associated fatty liver disease (MAFLD), metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol-related liver disease (MetALD), and alcoholic liver disease (ALD) instead of non-alcoholic fatty liver disease (NAFLD). …”
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Alpha-Lipoic Acid and Metformin Combination Therapy Synergistically Activate Nrf2-AMPK Signaling Pathways to Ameliorate Cognitive Dysfunction in Type 2 Diabetic Encephalopathy: A P... by Abdulmajeed F. Alrefaei, Mohamed E. Elbeeh

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Utility of measurement of left ventricular global longitudinal strain by two-dimensional speckle-tracking echocardiography to predict cardiovascular events in patients with left ve... by Susheel Kumar Malani, Digvijay Nalawade, Sridevi Chigulapalli, Shubhangi Kanitkar, Ajitkumar Jadhav, Madhura Gandhi

“…Conclusions: In this pilot study, LV GLS assessed through 2D STE shows promise as an effective predictor of cardiovascular events in LVSD, potentially surpassing traditional parameters. …”
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Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease by Yinghua Jing, Imis Dogan, Rena Theda Overbeck, Kathrin Reetz, Sandro Romanzetti

“…ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. …”
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Association between atherogenic index of plasma and all-cause mortality and cardiovascular disease among individuals with non-alcoholic fatty liver disease or metabolic dysfunction... by Jialu Lv, Jiangnan Yao, Leyi Zheng, Jiaxin Shao, Jijie Jin, Qianrong Zheng, Jiayi Teng, Jianghua Zhou, Fuman Cai, Pan Huang, Xuepei Jiang

“…Conclusion This study showed that AIP is an effective tool for predicting CVD risk and mortality in patients with NAFLD and MASLD. …”
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Theaflavin-3,3'-digallate alleviates glucolipotoxicity-induced insulin secretion dysfunction in pancreatic β-TC-6 cells and zebrafish via anti-ferroptotic mechanisms by activating... by Kaixi Wang, Huanqing Zhu, Jiaxin Kang, Shuna Chen, Puming He, Youying Tu, Bo Li

“…Here, the palmitic acid (PA)-induced pancreatic β-TC-6 cells and high fat-/high glucose-induced zebrafish were used. The effects of theaflavin-3,3’-digallate (TF3) on glucolipotoxicity-induced insulin secretion dysfunction, ferroptosis and endoplasmic reticulum (ER) stress were investigated by a variety of molecular biological approaches, inductively coupled plasma-mass spectrometry (ICP-MS), transmission electron microscopy (TEM) and widely targeted metabolomics analysis. …”
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Prolonged impacts of sodium glucose cotransporter-2 inhibitors on metabolic dysfunction-associated steatotic liver disease in type 2 diabetes: a retrospective analysis through magn... by Agena Suzuki, Akinori Hayashi, Satoshi Oda, Rei Fujishima, Naoya Shimizu, Kenta Matoba, Tomomi Taguchi, Takuya Toki, Takeshi Miyatsuka

“…The beneficial effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors in people with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD) have been suggested in several reports based on serological markers, imaging data, and histopathology associated with steatotic liver disease. …”
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Metabolic dysfunction-associated fatty liver in type 2 diabetes mellitus patient: can a systematic review of and meta-analysis of commonly used TCM-preparation shed light on their... by Jingsi Cao, Tingting Bao, Jingxian Cao, Xuechun Fan, Yanyan Wang, Jing Yu, Ying Wang, RuiXue Deng, Jingjing Shi, Changlong Shen, Qingwei Li, Jia Mi

“…BackgroundType 2 diabetes mellitus (T2DM) and Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) are mutually causal, which can jointly promote the development of the disease. …”
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P-19 ASSOCIATION OF TM6SF2 GENE POLYMORPHISMS WITH CARDIOVASCULAR RISK IN PATIENTS WITH METABOLIC DYSFUNCTION–ASSOCIATED STEATOTIC LIVER DISEASE (MASLD) IN A HISPANIC ADULT POPULAT... by LUISA FERNANDA SANTOS CUERVO, Maria Claudia Noguera Santamaria, Carlos Andres Ortiz Trujillo, Fernando Suarez Obando, Adriana Varon Puerta

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An Observational Study on the Reversibility of Left Ventricular Diastolic Dysfunction, Impaired Left Ventricular Ejection Fraction and Abnormal Left Ventricular Mass with Levothyro... by Abhirup Chatterjee, Anupam Mandal, Sattik Siddhanta, Rajdip Sen

“…Persistent subclinical hypothyroidism (SCH) is also a known risk factor for cardiomyopathy and heart failure. Yet, the direct effect of hypothyroidism on the heart, independent of its effect on loading function remains to be elucidated. …”
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Nonlinear associations of the hs-CRP/HDL-C index with metabolic dysfunction-associated steatotic liver disease and advanced liver fibrosis in US adults: insights from NHANES 2017–2... by Bin Liang, Xue Qiu, Jiansheng Huang, Yequan Lu, Hairong Shen, Jianchao Ma, Yongyu Chen

“…Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is a globally widespread chronic liver condition that may progress to severe liver diseases, including advanced liver fibrosis. …”
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Holy Basil (<i>Ocimum sanctum</i> L.) Flower and Fenofibrate Improve Lipid Profiles in Rats with Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD): The Role of Choli... by Siraphat Taesuwan, Jakkapong Inchai, Konpong Boonyingsathit, Chanika Chimkerd, Kunchit Judprasong, Pornchai Rachtanapun, Chatchai Muanprasat, Chutima S. Vaddhanaphuti

“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to choline metabolism. …”
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Impact of Metabolic Dysfunction-Associated Fatty Liver Disease of Varying Severity on Antiviral Treatment Outcomes and Clinical Prognosis in Patients with Chronic Hepatitis B: A Sy... by Qianqian Zhu, Chengde Su, Mingdan Li, Yali Xu, Qian Liu, Ying Zhang, Xinyi Zhang, Qiuxiang Li, Huajun Wang, Yawen Luo, Ping Yang

“…Abstract Introduction The coexistence of hepatitis B virus (HBV) infection and metabolic dysfunction-associated fatty liver disease (MAFLD) is becoming increasingly common. …”
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