Showing 1,781 - 1,800 results of 8,597 for search 'effective dysfunction', query time: 0.14s Refine Results
  1. 1781

    Atherosclerosis and Insulin Resistance: Is There a Link Between Them? by Alina Diduța Brie, Ruxandra Maria Christodorescu, Roxana Popescu, Ovidiu Adam, Alexandru Tîrziu, Daniel Miron Brie

    Published 2025-05-01
    “…Compelling evidence indicates that IR independently predicts the progression of atherosclerotic plaques, even in non-diabetic individuals, and operates through both traditional risk factors and direct vascular effects. Understanding and targeting the IR–ATS axis is essential for the effective prevention and management of cardiovascular disease.…”
    Get full text
    Article
  2. 1782
  3. 1783
  4. 1784
  5. 1785

    The synergistic extract of Zophobas atratus and Tenebrio molitor regulates neuroplasticity and oxidative stress in a scopolamine-induced cognitive impairment model by Ngoc Buu Tran, Haesung Lee, Myoung-Geun Ji, Long Ngo Hoang, Sook-Jeong Lee

    Published 2025-04-01
    “…Additionally, scopolamine-induced glutamatergic/GABAergic dysfunction was markedly improved following treatment with the ZaTm mixture. …”
    Get full text
    Article
  6. 1786

    Histological profiling of the extracellular matrix of streptozotocin-induced diabetic nephropathy in experimental mice and rats, an analytical study by Anas K. Al Makhzoomi

    Published 2025-04-01
    “…It also evaluates the effectiveness of pharmacological strategies in treating GAG changes. …”
    Get full text
    Article
  7. 1787
  8. 1788

    INFLUENCE OF ROSUVASTATIN ON VASCULAR ENDOTHELIUM FUNCTIONAL STATE AND SYSTEMIC INFLAMMATION IN PATIENTS WITH ISCHEMIC HEART DISEASE AND DIABETES MELLITUS by I. M. Fushtey, S. L. Podsevahina, O. I. Palamarchuk, O. V. Tkachenko, I. A. Kulinich

    Published 2022-12-01
    “…Vascular endothelial dysfunction had a close correlation with markers of systemic inflammation, which was exacerbated by the presence of insulin resistance. …”
    Get full text
    Article
  9. 1789
  10. 1790

    Toxicity of antimony in housefly after whole-life-cycle exposure: Changes in growth, development, redox homeostasis, mitochondrial function, and fecundity by Yuming Zhang, Jinghua Lv, Xiaoli Sun, Yiwen Zhang, Menghua Shao, Bingbing Shi, Yajie Zhang, Jihai Gu, Chenchen Zhao, Fengsong Liu

    Published 2025-01-01
    “…The exposure of Sb (0.7–70 mM) to houseflies resulted in a range of adverse effects, including developmental retardation, locomotor inhibition, gut damage, oxidative stress, and mitochondrial dysfunction in the houseflies. …”
    Get full text
    Article
  11. 1791

    Rutaecarpine Protects Human Endothelial Cells from Oxidative-Stress-Induced Apoptosis via TRPV1- and AhR-Mediated Nrf2 Activation by Chae Yeon Kim, Gi Ho Lee, Seung Yeon Lee, Anh Thi Ngoc Bui, Hye Gwang Jeong

    Published 2025-05-01
    “…These findings suggest that RUT exerts protective effects against oxidative-stress-induced apoptosis by controlling the Nrf2 signaling pathway in endothelial cells.…”
    Get full text
    Article
  12. 1792

    Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway by Luo X, Chen L, Xu J, Li J

    Published 2025-01-01
    “…GO and KEGG were used for functional analysis. The effect of NXT on warfarin anticoagulation was then tested in rats by analyzing coagulation factors in blood before and after drug administration. …”
    Get full text
    Article
  13. 1793

    Peripheral blood lymphocyte subsets of Chinese adults with liver steatosis by Xiaxiao Yan, Jing Li, Qiang Wang, Tengda Xu, Dong Wu

    Published 2025-04-01
    “…Abstract To evaluate the effect of liver steatosis on systematic cellular immunity through the changes of peripheral blood lymphocyte subsets, we retrospectively reviewed subjects receiving lymphocyte subtyping during annual medical check-ups. …”
    Get full text
    Article
  14. 1794

    Chronic metabolic stress impairs lymphatic contractility via activation of KATP channels in a mouse model of Type-2 diabetes by Jorge A. Castorena-Gonzalez, Hae Jin Kim, Michael J. Davis

    Published 2025-04-01
    “…The equivalent concentration of mannitol, an osmotic control, did not result in any significant changes in lymphatic contractile function. Lymphatic dysfunction induced by high glucose was rescued by GLIB (1 mM), and lymphatic vessels from Kir6.1−/− mice were largely resistant to the inhibitory effects of high glucose.DiscussionOur results suggest that a substantial fraction of lymphatic contractile impairment in db/db mice is mediated by the activation of KATP channels in lymphatic muscle cells, in part due to chronic metabolic stress associated with elevated glucose.…”
    Get full text
    Article
  15. 1795

    Vascular Aging in Ischemic Stroke by Lian Liu, Bo Zhao, Yueyang Yu, Wenwei Gao, Weitu Liu, Lili Chen, Zhongyuan Xia, Quan Cao

    Published 2024-08-01
    “…We have emphasized the detrimental effects of endothelial dysfunction and vascular remodeling influenced by oxidative stress and inflammatory response on vascular aging and IS. …”
    Get full text
    Article
  16. 1796
  17. 1797

    Nutritional aphrodisiacs: Biochemistry and Pharmacology by Haitham Al-Madhagi, Abd Alraouf Tarabishi

    Published 2024-01-01
    “…In 2022, the global prevalence of erectile dysfunction (ED) was estimated to be at least 150 million cases. …”
    Get full text
    Article
  18. 1798

    Neutrophils unveiled in chronic lymphocytic leukemia by Sheighlah McManus, Sheighlah McManus, Priyanka Khare, Maria Teresa S. Bertilaccio

    Published 2025-08-01
    “…It also examines the effects of CLL treatments, including chemotherapy, immunotherapy and targeted therapies, on neutrophils’ count and function, stressing the need for improved strategies to manage therapy-induced immune dysfunction. …”
    Get full text
    Article
  19. 1799
  20. 1800

    Zinc-Based Nanoparticles, but Not Silicon-Based Nanoparticles, Accumulate in Mitochondria and Promote Cell Death in Liver Cancer Cells by Pieretti JC, Horne TL, García-Villasante N, Seabra AB, Muntané J

    Published 2024-11-01
    “…ZnO induced apoptosis and necroptosis in HepG2 and SNU449, respectively.Keywords: apoptosis, cell respiration, hepatocellular carcinoma, metastasis, mitochondrial dysfunction…”
    Get full text
    Article