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1781
Atherosclerosis and Insulin Resistance: Is There a Link Between Them?
Published 2025-05-01“…Compelling evidence indicates that IR independently predicts the progression of atherosclerotic plaques, even in non-diabetic individuals, and operates through both traditional risk factors and direct vascular effects. Understanding and targeting the IR–ATS axis is essential for the effective prevention and management of cardiovascular disease.…”
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1782
AI-driven cognitive telerehabilitation for stroke: a randomized controlled trial
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1783
Story reading with incidental comprehension and memory: left hemisphere dominance
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1784
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1785
The synergistic extract of Zophobas atratus and Tenebrio molitor regulates neuroplasticity and oxidative stress in a scopolamine-induced cognitive impairment model
Published 2025-04-01“…Additionally, scopolamine-induced glutamatergic/GABAergic dysfunction was markedly improved following treatment with the ZaTm mixture. …”
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1786
Histological profiling of the extracellular matrix of streptozotocin-induced diabetic nephropathy in experimental mice and rats, an analytical study
Published 2025-04-01“…It also evaluates the effectiveness of pharmacological strategies in treating GAG changes. …”
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1787
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1788
INFLUENCE OF ROSUVASTATIN ON VASCULAR ENDOTHELIUM FUNCTIONAL STATE AND SYSTEMIC INFLAMMATION IN PATIENTS WITH ISCHEMIC HEART DISEASE AND DIABETES MELLITUS
Published 2022-12-01“…Vascular endothelial dysfunction had a close correlation with markers of systemic inflammation, which was exacerbated by the presence of insulin resistance. …”
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1789
Mitotherapy in Alzheimer’s and Parkinson’s diseases: A systematic review of preclinical studies
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1790
Toxicity of antimony in housefly after whole-life-cycle exposure: Changes in growth, development, redox homeostasis, mitochondrial function, and fecundity
Published 2025-01-01“…The exposure of Sb (0.7–70 mM) to houseflies resulted in a range of adverse effects, including developmental retardation, locomotor inhibition, gut damage, oxidative stress, and mitochondrial dysfunction in the houseflies. …”
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1791
Rutaecarpine Protects Human Endothelial Cells from Oxidative-Stress-Induced Apoptosis via TRPV1- and AhR-Mediated Nrf2 Activation
Published 2025-05-01“…These findings suggest that RUT exerts protective effects against oxidative-stress-induced apoptosis by controlling the Nrf2 signaling pathway in endothelial cells.…”
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1792
Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway
Published 2025-01-01“…GO and KEGG were used for functional analysis. The effect of NXT on warfarin anticoagulation was then tested in rats by analyzing coagulation factors in blood before and after drug administration. …”
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1793
Peripheral blood lymphocyte subsets of Chinese adults with liver steatosis
Published 2025-04-01“…Abstract To evaluate the effect of liver steatosis on systematic cellular immunity through the changes of peripheral blood lymphocyte subsets, we retrospectively reviewed subjects receiving lymphocyte subtyping during annual medical check-ups. …”
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1794
Chronic metabolic stress impairs lymphatic contractility via activation of KATP channels in a mouse model of Type-2 diabetes
Published 2025-04-01“…The equivalent concentration of mannitol, an osmotic control, did not result in any significant changes in lymphatic contractile function. Lymphatic dysfunction induced by high glucose was rescued by GLIB (1 mM), and lymphatic vessels from Kir6.1−/− mice were largely resistant to the inhibitory effects of high glucose.DiscussionOur results suggest that a substantial fraction of lymphatic contractile impairment in db/db mice is mediated by the activation of KATP channels in lymphatic muscle cells, in part due to chronic metabolic stress associated with elevated glucose.…”
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1795
Vascular Aging in Ischemic Stroke
Published 2024-08-01“…We have emphasized the detrimental effects of endothelial dysfunction and vascular remodeling influenced by oxidative stress and inflammatory response on vascular aging and IS. …”
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Nutritional aphrodisiacs: Biochemistry and Pharmacology
Published 2024-01-01“…In 2022, the global prevalence of erectile dysfunction (ED) was estimated to be at least 150 million cases. …”
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1798
Neutrophils unveiled in chronic lymphocytic leukemia
Published 2025-08-01“…It also examines the effects of CLL treatments, including chemotherapy, immunotherapy and targeted therapies, on neutrophils’ count and function, stressing the need for improved strategies to manage therapy-induced immune dysfunction. …”
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Zinc-Based Nanoparticles, but Not Silicon-Based Nanoparticles, Accumulate in Mitochondria and Promote Cell Death in Liver Cancer Cells
Published 2024-11-01“…ZnO induced apoptosis and necroptosis in HepG2 and SNU449, respectively.Keywords: apoptosis, cell respiration, hepatocellular carcinoma, metastasis, mitochondrial dysfunction…”
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