Development of a novel diagnostic model to monitor the progression of metabolic dysfunction-associated steatotic liver disease to hepatocellular carcinoma in females by Xiaoning Gan, Yun Zhou, Yonghao Li, Lin Xu, Guolong Liu

“…Effective methods for monitoring MASLD-HCC progression in females have not yet been developed. …”
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Mechanisms, assessment, and exercise interventions for skeletal muscle dysfunction post-chemotherapy in breast cancer: from inflammation factors to clinical practice by Pei Zhong, Pei Zhong, Xizhuang Li, Xizhuang Li, Jiehua Li

“…However, its toxic side effects, along with cancer-related paraneoplastic syndromes, can lead to the loss of skeletal muscle mass and function, impairing physical abilities and increasing the risk of complications during treatment. …”
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Efficacy of Mucuna pruriens (L.) DC. in treating diabetes, Parkinson’s disease, and erectile dysfunction—a review of clinical and preclinical trials by Ravindra Verma, Vaibhav Misra, Prakash S. Bisen

“…Among the most common medical problems experienced by older adults (over 60 years) are diabetes, Parkinson’s disease (PD), and erectile dysfunction (ED). The potential use of Mucuna pruriens in treating type 2 diabetes (T2D), PD, and ED is being investigated. …”
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Intraoperative transcutaneous electrical acupoint stimulation combined with anesthesia to prevent postoperative cognitive dysfunction: A systematic review and meta-analysis. by Lin Gan, Kecheng Qian, Jinding Yang, Qian Cai, Qinyu Ye, Mengyuan Dai, Zhaoxing Jia, Tianxiang Jiang, Congcong Ma, Xianming Lin

“…<h4>Background</h4>Postoperative cognitive dysfunction (POCD) is associated with an increased risk of dementia and may lead to chronic neurodegeneration. …”
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Histones post-translational modifications associated with the development of metabolic dysfunction-associated fatty liver disease. Part 3. Histon acetylation by O.E. Abaturov, A.O. Nikulina

“…The authors emphasize that an increase in the representation of acetylated markers is associated with the progression of metabolic dysfunction-associated fatty liver disease (MAFLD). …”
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Impact of drug therapy on long-term prognosis in patients with ischemic chronic heart failure with preserved ejection fraction and renal dysfunction by D. A. Lashkul

“…Aim. To investigate the effect of modern combined drug therapy for long-term prognosis in patients with ischemic HFpEF and renal dysfunction. …”
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Oyster-derived anticoagulant peptide mitigates thrombin-induced barrier dysfunction and prothrombotic phenotype in human pulmonary microvascular endothelial cells by Shuzhen Cheng, Siyi Wang, Ximing Yang, Minghao Xie, Qi Yang, Lushun Yuan, Ming Du

“…Thrombin blockers have been shown to be effective for various pathological conditions, but their use is limited due to the potential for serious bleeding adverse effects. …”
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Glycemic variability in type 2 diabetic patients with metabolic dysfunction-associated steatotic liver disease: a case-control study by Yueqiu Wang, Jing Liu, Yaoqin Yang, Qiong Wang, Yiqiong Sun, Ruiting Shen, Mingchen Zhang

“…Aims A case-control study was conducted to assess glycemic variability (GV) in individuals diagnosed with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes mellitus (T2DM), as well as in those with either condition independently.Methods This study encompassed 2897 consecutive inpatients diagnosed with diabetes at the Department of Endocrinology, Ningbo No.2 Hospital. …”
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Consensus Statement on Metabolic Dysfunction‐Associated Steatotic Liver Disease in Children and Adolescents From the Joint TASL‐TSPGHAN Expert Committee by Yu‐Cheng Lin, Fang‐Min Liao, Hsun‐Ching Chao, An‐Chyi Chen, Yung‐Ming Jeng, Chieh‐Chung Lin, Mao‐Meng Tiao, Yao‐Jong Yang, Chun‐Yan Yeung, Huey‐Ling Chen, Yen‐Hsuan Ni

“…ABSTRACT Background and Objective Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most prevalent chronic liver condition in children and adolescents, driven by the global rise in pediatric obesity. …”
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Transplantation of Umbilical Cord-Derived Mesenchymal Stem Cells Attenuates Surgical Wound-Induced Blood-Brain Barrier Dysfunction in Mice by Jie Yang, Hongyu Li, Mingzi Ran, Shuxu Yang, Kui Ma, Cuiping Zhang, Minglu Xiao, Yuguang Yang, Xiaobing Fu, Siming Yang

“…Interestingly, UC-MSCs treatment also had positive effects on wound healing while protecting the BBB dysfunction induced by surgical wound compared to IL-6-AB treatment. …”
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Combination Therapy of Half-Dose Resmetirom and Metformin Attenuates Metabolic Dysfunction-Associated Steatohepatitis Through Improving Cholesterol Metabolism and Inflammation by Wenxiu Liu, Fan Yao, Jinghan Wang, Nan Shao, Xinxin Cao, Zhengqi Dong, Bin Zhang, Xiaobo Sun

“…<b>Background/Objectives</b>: Metabolic dysfunction-associated steatohepatitis (MASH) has become the leading cause of hepatocellular carcinoma and liver disorders globally. …”
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Investigating imaging network markers of cognitive dysfunction and pharmacoresistance in newly diagnosed epilepsy: a protocol for an observational cohort study in the UK by Anthony Guy Marson, Marta García-Fiñana, Christophe de Bézenac, Gus Baker, Perry Moore, Nicola Leek, Rajiv Mohanraj, Leonardo Bonilha, Mark Richardson, Simon Keller

“…Although most existing work has examined chronic epilepsy, newly diagnosed patients present a unique opportunity to understand the underlying biology of epilepsy and predict effective treatment pathways. The objective of this prospective cohort study is to examine whether cognitive dysfunction is associated with measurable brain architectural and connectivity impairments at diagnosis and whether the outcome of antiepileptic drug treatment can be predicted using these measures.Methods and analysis 107 patients with newly diagnosed focal epilepsy from two National Health Service Trusts and 48 healthy controls (aged 16–65 years) will be recruited over a period of 30 months. …”
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Case Report: Amelioration of severe metabolic dysfunction-associated steatohepatitis after switching from conventional GLP-1RAs to tirzepatide by Yuki Oe, Yuki Oe, Takashi Omori, Eriko Aimono, Shin Furukawa, Hirohiko Kitakawa, Masatoshi Tateno, Kiyoshi Sakai, Kyu Yong Cho, Kyu Yong Cho

“…Metabolic dysfunction-associated steatohepatitis (MASH) has cardiometabolic risk factors, such as obesity and type 2 diabetes, and has been reported to have a potentially higher risk of mortality than conventional steatotic liver diseases. …”
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DKK3 promotes renal fibrosis by increasing MFF-mediated mitochondrial dysfunction in Wnt/β-catenin pathway-dependent manner by Jianling Song, Yanxia Chen, Yan Chen, Minzi Qiu, Wenliu Xiang, Ben Ke, Xiangdong Fang

“…Overexpression of MFF reversed in the inhibitory effect of DKK3 knockdown on cell damage.Conclusion Upregulation of DKK3 caused by m6A modification activated the Wnt/β-catenin pathway to increase MFF transcriptional expression, leading to mitochondrial dysfunction and oxidative stress, thereby promoting RF progression.…”
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A case report of bioprosthetic valve dysfunction after tricuspid valve replacement in a preschool patient: the contribution of pannus and calcification by T. V. Glushkova, E. A. Ovcharenko, A. V. Batranin, K. Yu. Klyshnikov, Yu. A. Kudryavtseva, L. S. Barbarash

“…Bioprosthetic valve dysfunction was mainly caused by the pannus  formation which was shown to encapsulate the anterior leaflet, resulting in its  total failure and severe stenosis (reduced effective orifice area). …”
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Association of pan-immune-inflammatory value with metabolic dysfunction-associated steatotic liver disease: findings from NHANES 2017–2020 by Lian-Zhen Huang, Ze-Bin Ni, Qi-Rong Yao, Wei-Feng Huang, Ji Li, Yan-Qing Wang, Jin-Yan Zhang

“…Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most common chronic liver disease worldwide. …”
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Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD by Yingxue Mei, Fei She, Ling Zhang, Gamin Kim, Ruomeng Li, Xiuzhi Zheng, Zonghai Wang, Renxuan Chen, Long Wang, Dongmei Chen, Jungho Kim, Tao Zhang, Tae Ho Lee

“…The rescue of neuronal loss by ZIPK downregulation effectively alleviated TBI-induced behavioral deficits by preserving motor and cognitive abilities in vivo, supporting the decisive role of ZIPK dysregulation in TBI-associated neuronal dysfunctions by modulating neuronal survival. …”
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Machine learning models for predicting metabolic dysfunction-associated steatotic liver disease prevalence using basic demographic and clinical characteristics by Gangfeng Zhu, Yipeng Song, Zenghong Lu, Qiang Yi, Rui Xu, Yi Xie, Shi Geng, Na Yang, Liangjian Zheng, Xiaofei Feng, Rui Zhu, Xiangcai Wang, Li Huang, Yi Xiang

“…Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global health concern that necessitates early screening and timely intervention to improve prognosis. …”
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Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment by Mengqiao Cui, Xiaoyuan Pan, Zhijie Fan, Shulin Wu, Ran Ji, Xianlei Wang, Xiangxi Kong, Zhou Wu, Lingzhen Song, Weiyi Song, Jun-Xia Yang, Hongjie Zhang, Hongxing Zhang, Hai-Lei Ding, Jun-Li Cao

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Mitigating Cellular Dysfunction Through Contaminant Reduction in Synthetic circRNA for High‐Efficiency mRNA‐Based Cell Reprogramming by Ziwei Zhang, Weiyu Li, Xiangyu Ren, Dengwang Luo, Xiushuang Yuan, Li Yu, Daming Wang, Yuhong Cao

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