SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19 by Hayder M. Al‐kuraishy, Nawar R. Hussien, Marwa S. Al‐Niemi, Esraa H. Fahad, Ali K. Al‐Buhadily, Ali I. Al‐Gareeb, Sadiq M. Al‐Hamash, Christos Tsagkaris, Marios Papadakis, Athanasios Alexiou, Gaber El‐Saber Batiha

“…Therefore, the present study aimed to overview the causal relationship between dysfunctional high‐density lipoprotein and Covid‐19.…”
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Suprachiasmatic nucleus dysfunction induces anxiety- and depression-like behaviors via activating the BDNF-TrkB pathway of the striatum by Xiaotao Liang, Yuewen Ding, Xiaoyu Zhu, Jing Qiu, Xiaoqin Shen, Yifan Xiong, Jieli Zhou, Xiaoshan Liang, Wei Xie

“…Microinjection of the TrkB inhibitor ANA-12 can effectively reverse anxiety- and depression-like behaviors. …”
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Spectrofluorimetric determination of cyclic guanosine monophosphate in human nasal secretions: evaluating levels in healthy individuals and patients with olfactory dysfunction by Mohamed H. Abdelazim, Faisal Alsenani, Adnan Alharbi, Fahad H. Baali, Abdulaziz H. Baali, Maram H. Abduljabbar, Reem M. Alnemari, Majed A. Algarni

“…Abstract Cyclic guanosine monophosphate (cGMP) is a second messenger involved in olfactory signal transduction. cGMP levels modulate the sensitivity of olfactory neurons and are implicated in olfactory dysfunctions. Previous reports demonstrate that individuals with olfactory dysfunction exhibit lower cGMP levels in the nasal mucus, necessitating precise analytical quantitative methods. …”
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MRI contrast accumulation in features of cerebral small vessel disease: blood-brain barrier dysfunction or elevated vascular density? by Tomas Vikner, Anders Garpebring, Cecilia Björnfot, Jan Malm, Anders Eklund, Anders Wåhlin

“…However, high contrast accumulation may mainly reflect high vascularization, and to a lesser degree than previously recognized BBB dysfunction.…”
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Gustatory Dysfunction among a Sample of Depressed Egyptian Adults under Antidepressants Therapy: A Retrospective Cohort Study by Christine Mikhail, Khaled Elgaaly, Ahmed Abd El Latif Abd El Hamid, Olfat Shaker, Shereen Ali

“…It is quite clear that the ability to perceive taste sensations significantly affects food choice, which consequently affects health status in the long term. Gustatory dysfunction is a neglected symptom among the depressed patients and those under antidepressants therapy, although these patients are suspectable to oral problems, due to general self-negligence related to mental disease, fear of dental treatment, and side effects of varied medications utilized in psychiatry. …”
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Associations of genetic markers of the sympathoadrenal system and endothelial dysfunction with coronary heart disease on the example of a small Shoriya population by E. V. Mikhalina, T. A. Mulerova, V. N. Maksimov, M. I. Voevoda, M. Yu. Ogarkov

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MG53 deficiency mediated skeletal muscle dysfunction in chronic obstructive pulmonary disease via impairing mitochondrial fission by Liwei Liao, Ziwen Zheng, Mingming Deng, Weidong Xu, Qin Zhang, Zilin Wang, Chang Li, Jiaye Li, Yiding Bian, Kai Wang, Jinrui Miao, Ruixia Li, Yan Yin, Xiaoming Zhou, Gang Hou

“…The underlying mechanisms were investigated using multi-omics sequencing, live-cell imaging, and histological and molecular experiments. The effectiveness and safety of recombinant mitsugumin 53 in treating cigarette smoke-induced muscle dysfunction were evaluated in vitro and in vivo. …”
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Inhibiting MARCH5/Mfn2 signaling as an alternative strategy to protect cardiomyocytes from hypoxia-induced mitochondrial dysfunction by Faten Habrat Zoabi, Mulate Zerihun, Roy Lizarovich, Chiara Dalla Torre, Liron Davis, Offir Ertracht, Michal Barsheshet, Shaul Atar, Deborah E. Shalev, Marta De Zotti, Hanoch Senderowitz, Nir Qvit

“…Dysregulation of the MARCH5/Mfn2 signaling has been implicated in mitochondrial dysfunction, a key factor in cardiovascular diseases (CVDs). …”
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Association between cardiovascular health and metabolic dysfunction-associated steatotic liver disease: a nationwide cross-sectional study by Lian-Zhen Huang, Ze-Bin Ni, Wei-Feng Huang, Li-Ping Sheng, Yan-Qing Wang, Jin-Yan Zhang

“…Abstract Purpose Evidence concerning the effect of cardiovascular health (CVH) on the risk of metabolic dysfunctional-associated steatotic liver disease (MASLD) is scarce. …”
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Machine Learning-Based Non-Invasive Prediction of Metabolic Dysfunction-Associated Steatohepatitis in Obese Patients: A Retrospective Study by Jie Chen, Bo Zhang, Yong Cheng, Yuanchen Jia, Biao Zhou

“…<b>Objectives</b>: We aimed to develop and validate machine learning (ML) models that integrate clinical and laboratory data for the non-invasive prediction of metabolic dysfunction-associated steatohepatitis (MASH) in an obese population. …”
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Comparative assessment of structural and tear film alterations in rabbit meibomian gland dysfunction models using chemical and electrocauterization techniques by Deeksha Prasad, Saumya Jakati, Kiran Kumar Bokara, Sayan Basu, Vivek Singh, Pragnya Rao Donthineni

“…Abstract Meibomian gland dysfunction (MGD) constitutes the most common cause of dry eye disease (DED), where altering meibum or lipids result in tear film instability. …”
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Loss of endothelial ZEB2 in mice attenuates steatosis early during metabolic dysfunction-associated steatotic liver disease by Wouter Dheedene, Stefaan Verhulst, Louise Demuynck, Bram Callewaert, Willeke de Haan, Stefan Vinckier, Jore Van Wauwe, Petra Vandervoort, Marleen Lox, Mathias Stroobants, Renaud Lavend’homme, Wilfred F. J. van IJcken, Elizabeth A. V. Jones, An Zwijsen, Marc Jacquemin, Leo A. van Grunsven, Kimberly Martinod, Danny Huylebroeck, Eskeatnaf Mulugeta, Aernout Luttun

“…Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease, features liver sinusoidal endothelial cell (LSEC) alterations with ill-defined driving factors. …”
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Mild intermittent hypoxia may improve autonomic dysfunction in persons living with spinal cord injury: a preliminary snapshot by Alexandra E. Soltesz, Alexandra E. Soltesz, Fei Zhao, Fei Zhao, Jill M. Wecht, Jill M. Wecht, Jason H. Mateika, Jason H. Mateika, Jason H. Mateika, Gino S. Panza, Gino S. Panza, Gino S. Panza

“…Persons with spinal cord injuries often suffer from autonomic dysfunction, sleep disordered breathing, and impaired mitochondrial capacity. …”
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Dynamics of laboratory markers of endothelial dysfunction in patients with psoriatic arthritis under the influence of the interleukin-17A inhibitor netakimab by A. V. Petrov, O. A. Pritulo, A. A. Petrov

“…Objective: a comparative evaluation of the effect of the interleukin-17A inhibitor (iIL) netakimab (NTK) and methotrexate (MTX) on laboratory markers of endothelial dysfunction in patients with psoriatic arthritis (PsA) in comparison with the dynamics of clinical efficacy indicators during 6 months of therapy.Material and methods. …”
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Proteomic analysis of laser captured tubular tissues reveals complement activation and mitochondrial dysfunction in autoimmune related kidney diseases by Mengyun Xiao, Xianggeng Chi, Xiaohui Zhu, Zigan Xu, Yaoshuang Zou, Yue Peng, Shaodong Luan, Jingjing Dong, Yong Dai, Lianghong Yin

“…Future research should validate the complement-mitochondrial-EMT pathway axis and explore the effects and mechanisms of CFB inhibitors in alleviating ARKD progression.…”
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Dynamics of fibrotic and vascular endothelial dysfunction markers in elderly hypertensive patients after ischemic stroke receiving beta-blockers by O. A. Osipova, E. V. Gosteva, O. N. Belousova, S. G. Gorelik, N. I. Klyushnikov, Yu. A. Lykov, A. N. Khachaturov, V. V. Bukatov

“…Aim. To compare the effect of beta-blocker therapy (bisoprolol and nebivolol) on the dynamics of fibrotic and vascular endothelial dysfunction markers in elderly hypertensive patients after ischemic stroke (IS).Material and methods. …”
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Role of Growth Hormone Therapy in Metabolic-Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-Analysis by Deep Dutta, Lakshmi Nagendra, Ritin Mohindra, Saptarshi Bhattacharya, Ameya Joshi, ABM Kamrul-Hasan

“…Multiple observation studies and meta-analysis have linked growth hormone (GH) deficiency with metabolic-dysfunction-associated steatotic liver disease (MASLD). …”
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Propolis extract nanoparticles alleviate diabetes-induced reproductive dysfunction in male rats: antidiabetic, antioxidant, and steroidogenesis modulatory role by Abram B. Emil, Neven H. Hassan, Sally Ibrahim, Eman I. Hassanen, Zienab E. Eldin, Sara E. Ali

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Comparative efficacy of different drugs in acute heart failure with renal dysfunction: a systematic review and network meta-analysis by Qianyu Lv, Qian Wu, Yingtian Yang, Lanlan Li, Xuejiao Ye, Shihan Wang, Yanfei Lv, Manshi Wang, Yushan Li

“…Hence, HDD and levosimendan may be optimal agents in the treatment of AHF with renal dysfunction.Systematic Review RegistrationPROSPERO, identifier (CRD42023454616).…”
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Impaired microglial glycolysis promotes inflammatory responses after intracerebral haemorrhage via HK2-dependent mitochondrial dysfunction by Yin Li, Hang Zhou, Xuchao He, Lingji Jin, Yuhan Zhu, Libin Hu, Majing Feng, Jun Zhu, Liang Wang, Yonghe Zheng, Shiwei Li, Zhiyuan Yan, Peili Cen, Junwen Hu, Zihang Chen, Xiaobo Yu, Xiongjie Fu, Chaoran Xu, Shenglong Cao, Yang Cao, Gao Chen, Lin Wang

“…Results: Neurological dysfunction was strongly correlated with decreased FDG-PET signals in the perihaematomal region, where microglial uptake of FDG was reduced. …”
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