Sevoflurane exposure in early life: mitochondrial dysfunction and neurotoxicity in immature rat brains without long-term memory loss by Lin Qiu, Hongwei Li, Bingbing Li, Joakim Ek, Xiaoli Zhang, Yiwen Chen, Zehua Shao, Jie Zhang, Jiaqiang Zhang, Hongqi Lin, Changlian Zhu, Yiran Xu, Xiaoyang Wang

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The HNRNPC/CELF2 signaling pathway drives glycolytic reprogramming and mitochondrial dysfunction in drug-resistant acute myeloid leukemia by Xiang Ma, Haodong Li, Ziqi Zhao, Changchun Li, Man Wang, Lele Zhang, Yutong Zhao, Haipeng Su, Feng Wang, Jiai Hua

“…In drug-resistant AML cells, increased HNRNPC expression and decreased CELF2 expression were associated with upregulated glycolysis, enhanced glucose consumption, lactate production, and mitochondrial dysfunction. Knockdown of HNRNPC reduced glycolysis and cell invasion, while CELF2 knockdown reversed these effects. …”
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Anti-HBV treatment partially restores the dysfunction of innate immune cells and unconventional T cells during chronic HBV infection by Yiwen Shu, Yiwen Shu, Sumeng Li, Sumeng Li, Yanqin Du, Yanqin Du, Xin Zheng, Xin Zheng

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The mitochondrial dysfunction regulated by JAK2/STAT3 pathway leads to the necroptosis in the renal cells under patulin exposure by Yun Liu, Ruhan Yi, Xu Zhang, Xiance Sun, Jing Li, Ningning Wang, Xiaofeng Yao, Cong Zhang, Haoyuan Deng, Shaopeng Wang, Guang Yang

“…Patulin (PAT) is a common mycotoxin widely found in various agricultural products and fruits, which has obvious toxic effects on animals and humans. Some studies have shown that PAT can cause nephrotoxicity, but the exact mechanism remains to be elucidated. …”
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Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKα2 and inducing mitochondrial dysfunction by Xue Han, Ruyi Zheng, Jiajia Zhang, Yanan Liu, Ze Li, Guoxuan Liu, Jianing Zheng, Weiqi Li, Zijun Liang, Mengyang Wang, Jie Yu, Qiaojuan Shi, Huazhong Ying, Guang Liang

“…Cardiomyocyte-specific OTUD1 knockout prevents cardiac hypertrophy and dysfunction in both type 2 and type 1 diabetic male mice. …”
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Polymorphism of genes of hemostasis system, endothelial dysfunction and regulation of blood pressure in pregnant woman with preeclampsia and fetal growth retardation by T. O. Loskutova

“…Objective: To study the distribution and effect of blood clotting, endothelial dysfunction, and blood pressure regulator gene polymorphisms on the development of fetal growth retardation in women with preeclampsia (PE). …”
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Long term chlorantraniliprole exposure induced intestinal and cognitive impairment via inducing lipid and amino acid metabolism dysfunction by Xin-Yu Wang, Zi-Peng Li, Bi-Yun Feng, Jie Cheng, Ji-Xiao Zhu, Guang-Hui Xu, Wei-Feng Huang, Li-Tao Yi

“…Chlorantraniliprole, a widely used anthranilic diamide insecticide, has been linked to adverse effects on mammalian health, yet the precise toxicological mechanisms affecting intestine and brain remain unclear. …”
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The efficacy of platelet rich plasma in the treatment of erectile dysfunction: a systematic review and meta-analysis of randomized controlled trials by Qiancheng Mao, Yingying Yang, Yang Liu, Hongquan Liu, Gonglin Tang, Xiaofeng Wang, Yuanshan Cui, Jitao Wu

“…Additionally, in terms of IIEF, PRP showed significantly better efficacy than placebo at the first, third, and sixth months (p < 0.00001).Conclusions PRP shows more effectiveness in treating ED compared to placebo, offering hope as a potential alternative treatment for ED.…”
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Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection by Xiu Liu, Li Zhao, Deshen Liu, Lingna Zhao, Yonghua Tuo, Qinbao Peng, Fangze Huang, Zhengkun Song, Chuanjie Niu, Xiaoxia He, Yu Xu, Jun Wan, Peng Zhu, Zhengyang Jian, Jiawei Guo, Yingying Liu, Jun Lu, Sijia Liang, Shaoyi Zheng

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The influence of olfactory training on depressive symptoms and olfactory function in patients with olfactory dysfunction – A prospective observational pilot study by Emilie Keusters, Marnick Clijsters, Kristof Vansteelandt, Laura Van Gerven, Filip Bouckaert

“…The objective of our study is to look at the prevalence of depressive symptoms in patients with olfactory disorders and to examine the effect of OT on mood in patients who present with OD. …”
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Segmental Epidural Anaesthesia with Ropivacaine for Umbilical Hernia Repair in a Patient with Severe Cardiac Dysfunction: A Case Report by Sandip Baheti, Vaibhavavi Singh, Priya Singh

“…The present case underscores the effectiveness and safety of segmental epidural anaesthesia with low-concentration ropivacaine for high-risk cardiac patients undergoing non cardiac surgery. …”
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The Impact of Post-Operative Phrenic Nerve Dysfunction on Lung Function Parameters and Long-Term Outcomes After Lung Transplantation by Keita Nakanishi, Keita Nakanishi, Caroline Hillebrand, Thomas Schweiger, Stefan Schwarz, Shahrokh Taghavi, Peter Jaksch, Alberto Benazzo, Toyofumi Fengshi Chen-Yoshikawa, Konrad Hoetzenecker, Konrad Hoetzenecker

“…A rare but important complication after lung transplantation (LTx) is postoperative phrenic nerve dysfunction (PND). Diaphragmatic plication (DP) is a well-established treatment option for PND, however, the long-term effect of PND and DP on lung function parameters and survival after LTx are currently unknown. …”
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Case Report: Incidental late-onset Pompe disease diagnosis in a man with no clinical and instrumental evidence of neuromuscular dysfunction by Monica Sciacco, Sabrina Lucchiari, Letizia Bertolasi, Giacomo Pietro Comi, Giacomo Pietro Comi, Stefania Corti, Stefania Corti, Dario Ronchi, Dario Ronchi

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Evaluation and significance of cognitive dysfunction after cerebrovascular disease with convalescent rehabilitation. Assessment based on FIM, MMSE and HDS-R by Katsuo Usuda, Takahiko Uesaka, Takeshi Okubo, Takashi Shimada, Chieko Shimada, Haruhide Ito, Norihito Douko, Takuya Aoki, Mio Mizukami, Asami Onojima, Kenshiro Ikemoto, Kengo Kitagawa, Mayumi Takada, Naoaki Itamoto, Osami Shimada

“…To analyze the effectiveness of rehabilitation for patients with cognitive dysfunction after cerebrovascular disease at a rehabilitation hospital. 200 patients with cerebrovascular diseases who underwent rehabilitation were divided into two groups: 128 patients with cognitive dysfunction and 72 patients without cognitive dysfunction. …”
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Potential and mechanisms of indigenous Indonesian medicinal plants in treating sexual dysfunction: A systematic review and pharmacological network overview by Sukardiman, Roihatul Mutiah, Rosita Handayani

“…The epidemiology of Erectile Dysfunction (ED) continues to exhibit an increasing trend annually. …”
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Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults by Yi-Hsueh Liao, Wei-Liang Chen, Chung-Ching Wang, Ching-Huang Lai

“…Abstract The impact of airborne particulate matter and its metal components on autonomic nervous system (ANS) dysfunction in healthy subjects remains unclear. The aim of this study was to examine the effects of personal exposure to airborne particulate matter on the ANS in young, healthy adults. …”
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Postoperative analgesia with morphine promoting microglial activation and neuroinflammation induced by surgery aggravates perioperative neurocognitive dysfunction in aged mice by Xiuzhi Shao, Liping Xie, Jingwen Zhai, Mingyue Ge

“…Introduction: Perioperative neurocognitive dysfunction (PND) is a significant challenge for patients who need surgery worldwide. …”
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Metabolic Dysfunction-Associated Steatotic Liver Disease in the Korean General Population: Epidemiology, Risk Factors, and Non-Invasive Screening by Yong Jun Choi, Jooheon Park, Han-Ik Cho, Myung Geun Shin, Eun-Hee Nah

“…<b>Background/Objectives</b>: Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a contemporary classification of liver disease linked to metabolic dysfunction. …”
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Varied Response of EEG Rhythm to Different tDCS Protocols and Lesion Hemispheres in Stroke Subjects with Upper Limb Dysfunction by Chunfang Wang, Yuanyuan Chen, Peiqing Song, Hongli Yu, Jingang Du, Ying Zhang, Changcheng Sun

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Exposure to 6-PPD Quinone Disrupts Adsorption and Catabolism of Leucine and Causes Mitochondrial Dysfunction in <i>Caenorhabditis elegans</i> by Wei Wang, Yunhui Li, Dayong Wang

“…In <i>Caenorhabditis elegans</i>, we examined the effect of 6-PPDQ exposure at environmentally relevant concentrations (ERCs) on the content of leucine and underlying mechanisms. …”
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