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1261
Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review
Published 2025-06-01“…It examines key structural alterations, such as tight junction protein loss, endothelial dysfunction, and pericyte reduction, as well as functional changes including impaired immune regulation and transporter dysfunction. …”
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Qualitative study exploring the barriers and facilitators to low-dose aspirin adherence in pregnant women with placental dysfunction risk in the UK
Published 2025-03-01“…Low-dose aspirin (LDA) reduces placental dysfunction risk. However, adherence to LDA is suboptimal in pregnant women and may reduce its effectiveness.Objectives We aimed to explore the barriers and facilitators to LDA adherence in pregnant women with placental dysfunction risk.Design Qualitative semi-structured individual interviews were undertaken, and data were inductively thematically analysed.Setting A single NHS Trust in South West England, UK.Participants Pregnant women aged>18, recommended daily LDA for pregnancy indications. …”
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Resistance Training in Type II Diabetes Mellitus: Impact on Areas of Metabolic Dysfunction in Skeletal Muscle and Potential Impact on Bone
Published 2012-01-01“…The purpose of this review is to examine the role of resistance training in treating the dysfunction in skeletal muscle and the potential role for resistance training in treating the associated dysfunction in bone.…”
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Avanafil use in patients with erectile dysfunction and co-morbidities: Clinical insights from multiple aetiologies – A case series
Published 2025-04-01“…This case series aimed to evaluate the effects of avanafil as a treatment option for patients with ED and other co-morbidities. …”
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Intelligent decision support system for iterative analysis of dysfunctions of the institutional system of human capital development based on neural structures
Published 2025-01-01“…Intelligent analysis of dysfunctions of the institutional system of human capital development is an iterative process of extracting useful information and decision-making templates from organized or unorganized arrays of big data of different formats. …”
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Effect of back percussion along the meridian on lung function in patients with pulmonary dysfunction in recovery period of stroke (循经叩背对脑卒中恢复期合并肺功能障碍患者肺功能的影响)
Published 2022-10-01“…Objective To investigate the effect of back percussion along the meridian on lung function in patients with pulmonary dysfunction in recovery period of stroke. …”
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1267
Effect of cupping therapy with Chinese herbal decoction in the treatment of extremity dysfunction among patients with wind-phlegm obstruction type stroke (中药水罐治疗风痰阻络型中风患者肢体功能障碍效果观察)
Published 2021-10-01“…Objective To observe the effect of cupping therapy with Chinese herbal decoction in the treatment of extremity dysfunction among patients with wind-phlegm obstruction type stroke. …”
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Chronic Inflammation and Immune Dysregulation in Metabolic-Dysfunction-Associated Steatotic Liver Disease Progression: From Steatosis to Hepatocellular Carcinoma
Published 2025-05-01“…<b>Background/Objectives</b>: Metabolic-dysfunction-associated steatotic liver disease (MASLD) progresses from hepatic steatosis to hepatocellular carcinoma (HCC) as a result of systemic immunometabolic dysfunction. …”
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Bioinformatic analysis of molecular expression patterns during the development and progression of metabolic dysfunction-associated steatotic liver disease (MASLD)
Published 2025-03-01“…Abstract The global incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) continues to rise, primarily driven by the escalating obesity epidemic worldwide. …”
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1270
A comparative study of thrombolysis in cases of prosthetic mitral valve replacement dysfunction between intravenous alteplase and intravenous urokinase
Published 2025-01-01“…Conclusions: The use of alteplase and urokinase intravenously for thrombolysis in cases of post-MVR valve dysfunction has equivalent therapeutic effects.…”
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Therapeutic Challenges of Diabetes Mellitus-Related Erectile Dysfunction and The Potential Therapeutic Role of Medicinal Plants: A Narrative Review
Published 2025-04-01“…Diabetes mellitus-induced erectile dysfunction (DMED) affects various aspects of the patient’s quality of life, mental well-being, and relationship dynamics. …”
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Sinapic Acid Alleviated Inflammation-Induced Intestinal Epithelial Barrier Dysfunction in Lipopolysaccharide- (LPS-) Treated Caco-2 Cells
Published 2021-01-01“…Sinapic acid (SA) is a phenolic acid that has anti-inflammatory, antihyperglycemic, and antioxidant activities; meanwhile, it is also effective in the protection of inflammatory bowel disease (IBD), but the specific mechanisms remain unclear. …”
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Edaravone Improves Streptozotocin-Induced Memory Impairment via Alleviation of Behavioral Dysfunction, Oxidative Stress, Inflammation, and Histopathological Parameters
Published 2023-01-01“…In addition, no significant difference has been observed between the effect of 5 and 10 mg/kg EDV application. It was supposed that EDV managed to ameliorate memory dysfunction, discriminatory behavior, oxidative stress, and cellular antioxidant power in a dose-independent pattern in mice.…”
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Efficacy and safety of visnadine in the treatment of symptoms of sexual dysfunction in heterosexual women: a systematic review of randomized clinical trials
Published 2024-12-01“…This preliminary evidence shows visnadine as a potentially effective and safe option to alleviate some of the clinical symptoms of SD in heterosexual women. …”
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Identification of Systemic Drug Targets for Anti-cavernous Fibrosis in the Treatment of Erectile Dysfunction, Guided by Genome-Wide Mendelian Randomization
Published 2025-03-01“…The treatment of erectile dysfunction (ED) remains a significant challenge. Mendelian randomization (MR) is being increasingly utilized to identify novel therapeutic targets. …”
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Evaluating tissue plasminogen activator (tPA) in dialysis catheter dysfunction: A focus on fibrin sheath and risk factors
Published 2025-10-01“…Older age (p = 0.02), diabetes (p = 0.001), and smoking (P = 0.015) were identified as significant risk factors for catheter dysfunction. Conclusion: tPA therapy effectively restores catheter function in cases of fibrin sheath-related dysfunction. …”
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Natural active botanical metabolites: targeting AMPK signaling pathway to treat metabolic dysfunction-associated fatty liver disease
Published 2025-07-01“…Metabolic dysfunction-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD), has emerged as one of the most common chronic liver diseases globally, with a tendency to progress gradually. …”
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Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin
Published 2025-07-01“…Of note, quercetin, as an antioxidant, is effective in preventing mechanical stretch‐induced endothelial dysfunction by scavenging ROS. …”
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