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1181
Endothelial dysfunction in patients with chronic obstructive pulmonary disease: some aspects of medicamental treatment (a literature review)
Published 2021-02-01“…Therefore, modern treatment of COPD, in addition to the drugs approved by clinical protocols, must be supplemented by methods of endothelial dysfunction correction in the long-term management for patients beyond the exacerbation period, which at the same time have no negative effect on the disease course. …”
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1182
Clinical Observation on Xingnao Kaiqiao Acupuncture Combined with Repetitive Transcranial Magnetic Stimulation for Post-stroke Speech Dysfunction
Published 2017-12-01“…Objective:To observe the effect of Xingnao Kaiqiao acupuncture combined with repetitive transcranial magnetic stimulation on post-stroke speech dysfunction.Methods:A total of 48 patients with post-stroke speech dysfunction were randomly assigned to the observation group and control group with 24 patients in each group. …”
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1183
Myostatin Exacerbates Endothelial Dysfunction Induced by Uremic Toxin Indoxyl Sulfate and Is Associated with Hemodialysis Arteriovenous Access Complications
Published 2025-03-01“…Hemodialysis patients exhibit endothelial dysfunction, contributing to elevated cardiovascular risk and complications of the arteriovenous access. …”
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1184
Pioglitazone Ameliorates Atorvastatin-Induced Islet Cell Dysfunction through Activation of FFA1 in INS-1 Cells
Published 2019-01-01“…Ultimately, FFA1 may mediate the atorvastatin-induced pancreatic β-cell dysfunction and pioglitazone may ameliorate this deleterious effect through the upregulation of FFA1 expression.…”
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Studying targeted oxidation in diabetic cognitive dysfunction based on scientometrics analysis: research progress of natural product approaches
Published 2024-12-01“…PurposeThe aim is to provide new insights for researchers studying the pathogenesis of diabetic cognitive dysfunction and promoting the wider use of natural products in their treatment.MethodFirst, the Web of Science Core Collection was selected as the data source for a computerized literature search on oxidative stress and diabetic cognitive dysfunction (DCD). …”
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1188
Efficacy of electrical stimulation for post-stroke motor dysfunction: A protocol for systematic review and network meta-analysis.
Published 2024-01-01“…<h4>Objective</h4>This study aims to analyze the efficacy and safety of different electrical stimulation treatments for post-stroke motor dysfunction, and to quantitatively analyze the advantages between them and their possible benefits for patients.…”
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1189
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HO-1 Upregulation Attenuates Adipocyte Dysfunction, Obesity, and Isoprostane Levels in Mice Fed High Fructose Diets
Published 2014-01-01“…Methods and Results. We examined the effect of fructose, on adipogenesis in human MSCs in the presence and absence of CoPP, an inducer of HO-1. …”
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1192
Soluble Siglec-9 Improves Intestinal Barrier Function in a Mouse Model of Metabolic Dysfunction-Associated Steatohepatitis
Published 2025-05-01“…<b>Background/Objectives:</b> Metabolic dysfunction-associated steatohepatitis (MASH), characterized by liver inflammation, fibrosis, and fat accumulation, can develop into cirrhosis and liver cancer. …”
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1193
Mechanism of the Traditional Chinese Medicine Simiao Biejia Decoction Improves the Diabetes Mellitus-Induced Erectile Dysfunction in Rats
Published 2025-04-01“…Yuanyuan Liu,1,* Dalin Sun,2,* Dong Xing,1 Yiqi Rui,3 Yihan Jin,4 Peng Wang,3 Bin Cai,2 Chuyu Li,5 Chao Gao,5 Yugui Cui,5 Baofang Jin2 1School of Medicine, Southeast University, Nanjing, Jiangsu, 210003, People’s Republic of China; 2Department of Integrative Medicine and Andrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, 210009, People’s Republic of China; 3Department of General Surgery, Jiangsu Province Official Hospital, Geriatrich Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210024, People’s Republic of China; 4Reproductive Medicine Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, 210009, People’s Republic of China; 5State Key Laboratory of Reproductive Medicine and Offspring Health, Center of Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yugui Cui State Key Laboratory of Reproductive Medicine and Offspring Health, Center of Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, No. 368 Jiangdong North Road, Nanjing, Jiangsu, 210006, People’s Republic of China, Email cuiygnj@njmu.edu.cn Baofang Jin, Department of Integrative Medicine and Andrology, Zhongda Hospital, School of Medicine, Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing, Jiangsu, 210009, People’s Republic of China, Email hexiking@126.comObjective: Simiao Biejia (SMBJ) granules, a traditional Chinese herbal remedy, have been used to treat erectile dysfunction caused by diabetes mellitus (DMED). However, the molecular mechanisms underlying SMBJ’s therapeutic effects remain unclear. …”
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Nanovaccine loaded with seno-antigen target senescent cells to improve metabolic disorders of adipose tissue and cardiac dysfunction
Published 2025-12-01“…Following subcutaneous immunization, GK-NaV not only exhibited a noticeable antigen depot effect but also markedly activated specific cellular immune responses, enhancing the immunoreactivity and cytotoxic effects of CD8+T cells. …”
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Protective Role of H2S in High Glucose-Induced Cardiomyocyte and Endothelial Cell Dysfunction: A Mechanistic Review
Published 2025-05-01“…Its protective effects primarily stem from several mechanisms, including S-sulfhydration of proteins, reduction of cell death, alleviation of mitochondrial damage, improvement of ion channel dysfunction, interaction with nitric oxide, and modulation of angiogenesis. …”
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Rehabilitation of pelvic floor dysfunction after radiation therapy for a rare gynecological cancer: A case report
Published 2024-12-01“…Objective: Radiation therapy (RT) for gynecological cancers has significant effects on patients’ quality of life regarding sexual dysfunction, urinary incontinence (UI), fecal incontinence (FI), and psychological distress. …”
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Renal Dysfunction in a Patient With Crohn's Disease During Ustekinumab Treatment: A Case Report and Review of the Literature
Published 2024-01-01“…However, little is known about its potential adverse effects on renal function. We present the case of a 42-year-old man with Crohn's disease who developed chronic renal dysfunction during ustekinumab treatment, which resolved after discontinuing ustekinumab. …”
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Cholesterol overload in macrophages drives metabolic dysfunction-associated steatohepatitis via inhibiting 7-dehydrocholesterol reductase in mice
Published 2024-11-01“…Abstract Background Dietary cholesterol promotes metabolic dysfunction-associated steatohepatitis (MASH), with hepatic macrophages central to disease pathology. …”
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Dysfunctional sleep beliefs and sleep quality among Chinese university students: the mediating roles of depression, anxiety, and stress
Published 2025-07-01“…This study investigates the relationship between dysfunctional beliefs and attitudes about sleep (DBAS) and sleep quality among college students, with a focus on examining the mediating effects of anxiety, stress, and depression in this relationship. …”
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