Fenofibrate treatment during withdrawal reverses symptoms of ethanol-induced depression in male rats by Marcelo León, Camila Vásquez-Ulloa, Lucas Marambio-Ruiz, Diliana Pérez-Reytor, Eduardo Karahanian, Eduardo Karahanian

“…Fenofibrate reversed these behavioral and molecular effects, normalized PFC BDNF expression, and partially restored dendritic complexity. …”
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Cellular adaptations impact the biological activity of naphthalene diimide G-quadruplex ligands in ALT-positive osteosarcoma cells by Joanna Bidzinska, Lorenzo Di Pietro, Eisa Naghshineh, Cecilia Pandini, Filippo Doria, Nadia Zaffaroni, Paolo Gandellini, Stephen Neidle, Marco Folini

“…Here we have investigated the effects of two naphthalene diimide (NDI)-based G4 interacting agents (NMe2 and QN-302) in a pair of ALT-positive human osteosarcoma (U-2 OS and Saos-2) cell lines. …”
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Unstructured Electronic Health Records of Dysphagic Patients Analyzed by Large Language Models by Luisa Neubig, Deirdre Larsen, Melda Kunduk, Andreas M. Kist

“…We utilize clustering algorithms on the extracted diagnostic features to identify distinct groups of patients who share similar pathophysiological swallowing dysfunctions.Results: We found that basic NLP techniques often provide limited insights due to the high variability of the data. …”
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Cutaneous and systemic improvements in psoriasis patients after different biologic treatments in a real-world longitudinal prospective study by Epipode Ntawuyamara, Baoqing Deng, Yanhua Liang

“…We found that biologics have different effects on metabolic dysfunctions, such as SECU on glucose and GUSE on non-HDL.…”
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Level of Perceived Stress and Coping Mechanisms among MBBS Students at Government Medical College: A Prospective Observational Study from Delhi by Vikram Singh, Nandini Sharma, Shivani Rao, Priya Arora

“…Clinical significance: Screening students with a stress scale early on allows us to effectively help them manage stress through peer-support groups, incorporating mindfulness, physical activities, and counseling.…”
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Small Extracellular Vesicle (sEV) Uptake from Lung Adenocarcinoma and Squamous Cell Carcinoma Alters T-Cell Cytokine Expression and Modulates Protein Profiles in sEV Biogenesis by Hafiza Padinharayil, Jinsu Varghese, Pulikkottil Raphael Varghese, Cornelia M. Wilson, Alex George

“…This study examines the immunomodulatory effects of sEVs derived from lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC) on T cells. …”
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Clinical usefulness of hemoencephalography beyond the neurofeedback by Serra-Sala M, Timoneda-Gallart C, Pérez-Álvarez F

“…HEG pattern might be a useful marker to define maturation and future possible mental dysfunctions. Keywords: behavior, adolescents, development, psychiatry, diagnosis…”
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Grid-Based Characterization and Sustainable Planning for Fractured Urban Textures: A Case Study of Nanhao Village in Baotou by Haoyu Tian, Weidong Wang, Ting Hao

“…During urban development, significant contrasts between urban villages and their surrounding areas lead to the emergence of fragmented urban spaces, dysfunctionalities, cultural barriers, and, ultimately, to the formation of fractured urban textures centered on urban villages (FUT-UVs). …”
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F-box protein Fbx23 acts as a transcriptional coactivator to recognize and activate transcription factor Ace1. by Zhongjiao Liu, Kexuan Ma, Panpan Zhang, Siqi Zhang, Xin Song, Yuqi Qin

“…Accumulated PoAce1 protein is a dysfunctional form that no longer binds promoters of the target gene, including the cellulase genes cbh1 and eg1, the hemicellulase gene xyn11A, and the pigmentation-related gene abrB. …”
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Functional analyses of splice site variants in TCF12 by Angela Borst, Tilmann Schweitzer, Denise Horn, Erdmute Kunstmann, Eva-Maria König, Natalie Pluta, Eva Klopocki

“…Malfunctions during this process can lead to dysfunctional proteins and thus, to a variety of different human diseases. …”
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Cerebral blood flow change with fluid resuscitation in acute ischemic stroke by Joseph Miller, John Aidan Moloney, Noah Elagamy, Jacob Tuttle, Sam Tirgari, Sean Calo, Richard Thompson, Bashar Nahab, Christopher Lewandowski, Phillip Levy

“…BACKGROUND: In acute ischemic stroke (AIS), cerebral autoregulation becomes dysfunctional, impacting the brain’s ability to maintain cerebral blood flow (CBF) at adequate levels. …”
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Advanced lung cancer inflammation index is associated with mortality in critically ill patients with non-traumatic cerebral hemorrhage by Peng Zhong, Xiuyang Chen, Peng Miao, Yiming Xing, Yongfeng Li

“…ALI had a strong ability to distinguish in-hospital all-cause mortality (AUC = 0.853, 95% CI: 0.826–0.880, P < 0.001). A threshold effect was found (log-transformed ALI = 4.0), below which ALI was inversely related to mortality (P < 0.001), and above which the relationship leveled off. …”
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الوضوح الاستراتيجي وعلاقته بالركود التنظيمي ( دراسة تطبيقية لعينة من المصارف الأهلية العراقية by ليث علي يوسف الحكيم, ناتاليا أحمد القصير

“…Abstract The purpose of this research is to study the relationship between organizational aging and dysfunctional behavior in the Iraqi private banks. The importance of research includes rare of studies that investigated the relationships between variables (Strategic clarity, organizational slack). …”
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Evaluating self-assistance during functional reach with a passive hydrostatic exoskeleton under artificial impairment by Julia Manczurowsky, Henry Mayne, David Nguyen, Meghan Kenney, John Peter Whitney, Christopher J. Hasson

“…To address this question, we developed a passive hydrostatic exoskeleton (hEXO) that enables self-assistance and paired it with an artificial impairment paradigm using Dysfunctional Electrical Stimulation (DFES), which induces involuntary hand closure during reaching. …”
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Traditional Mongolian Medicine Qiqirigan-8 alleviates non-alcoholic fatty liver disease via restoring gut microbiota and metabolism by Dandan Yang, Dandan Yang, Wuyunsiqin, Wuyunsiqin, YanNiu, Hashentuya, Tana, Anna, Mingxing Ma, Wenhui Zhao, Menggenduxi, Minjie Wang, Minjie Wang

“…Fecal metagenomics and serum non-targeted metabolomics were used to reveal the effects of MMQ-8 on the gut microbiota and metabolism in mice with NAFLD. …”
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Impact of spinach thylakoid extract-induced 12-week high-intensity functional training on specific adipokines in obese males by Ayoub Saeidi, Pezhman Motamedi, Maha Hoteit, Zahra Sadek, Wiam Ramadan, Marjan Mansouri Dara, Abdullah Almaqhawi, Shahnaz Shahrbanian, Hossein Abednatanzi, Kurt A Escobar, Zhaleh Pashaei, Maisa Hamed Al Kiyumi, Ismail Laher, Hassane Zouhal

“…The proposed combination intervention may reverse obesity-induced insulin resistance and metabolic dysfunctions by positive regulation of CTRP-12/adipolin and KLF15 and simultaneous suppression of furin levels.…”
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Psychosocial Assessment as a Key Component in an Integrated, Personalized Care Pathway: A Protocol for a Low Back Pain Randomized Controlled Trial by Anna Anselmo, Maria Pagano, Francesco Corallo, Irene Cappadona, Davide Cardile, Fabrizio Russo, Alice Laudisio, Giuseppe F. Papalia, Angelo Quartarone, Rocco S. Calabrò

“…The analysis involves descriptive statistics, ANOVA, and correlation tests to evaluate treatment effects and psychosocial outcomes at multiple time points. …”
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Roles of Long Noncoding RNAs in Adipogenesis and Obesity Treatment: Insights from CRISPR-Cas9 Gene Editing by J Bindhu, Jeelani Gh Peerzada, M.S. Mohamed Jaabir, Crosswin Saravanan, Vishnu Shree T, S Tamilselvi, M.K.S Pavithra, M.E. Sinduja

“…Obesity represents a major health issue linked to various dysfunctions within adipose tissue. The equilibrium between energy storage and expenditure is vital for appropriate fat accumulation and lipid metabolism. …”
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New onset of isolated adrenocorticotropin deficiency associated with encephalopathy following coronavirus disease 2019 in a healthy elderly man by Yusuke Yamasaki, Ichiro Horie, Riyoko Shigeno, Shinpei Nishikido, Toshiyuki Ikeoka, Takuro Hirayama, Yohei Tateishi, Akira Tsujino, Atsushi Kawakami

“…At 13 months after his hospitalization, the patient’s neurological symptoms have not recurred and he has no endocrinological dysfunctions other than the remaining ACTH deficiency. …”
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Recent advances (2022–2024) in eye-tracking for Parkinson’s disease: a promising tool for diagnosing and monitoring symptoms by Laura Culicetto, Davide Cardile, Giulia Marafioti, Viviana Lo Buono, Francesca Ferraioli, Simona Massimino, Giuseppe Di Lorenzo, Chiara Sorbera, Amelia Brigandì, Carmelo Mario Vicario, Angelo Quartarone, Silvia Marino

“…Findings indicate that eye-tracking may offer valuable insights into both oculomotor and cognitive dysfunctions. Specific metrics such as saccade velocity, fixation duration, and pupil size have been correlated with disease severity. …”
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