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8501
Endurance and avoidance response patterns in pain patients: Application of action control theory in pain research.
Published 2021-01-01“…Distress-avoidance responders emerged as the most burdened, dysfunctional patient group concerning measures of stress, action control, maladaptive coping, and health. …”
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8502
Potential Resistance Mechanisms Exhibited by Cystic Fibrosis Patients Against SARS-CoV-2
Published 2025-06-01“…The potential resistance mechanisms include blood and extracellular ATP levels, a deleted/dysfunctional CFTR gene, ACE and ACE2 regulation and expression, ACE and ACE2 polymorphism effects, host proteins and SARS-CoV-2 interactions, and SMN1 and ACE/ACE2 interactions. …”
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8503
Zinc deficiency as possible link between immunosenescence and age-related diseases
Published 2025-05-01“…Recent findings on zinc’s cellular and molecular effects on immune health present zinc supplementation as a practical, accessible intervention for supporting healthier aging and improving quality of life. …”
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8504
Cerebral edema in drug addicts
Published 2014-01-01“…Background/Aim. The effect of drugs leaves permanent consequences on the brain, organic in type, followed by numerous manifestations, and it significantly affects the development of mental dysfunctions. …”
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8505
Application of Multidomain Cognitive Training in a Tele-Neurorehabilitation Setting for Treatment of Post-Stroke Cognitive Disorders
Published 2024-12-01“…Purpose: Cognitive dysfunctions are still very common in the chronic phase of stroke when patients are discharged from neurorehabilitation centers. …”
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8506
Evolution of a major drug metabolizing enzyme defect in the domestic cat and other felidae: phylogenetic timing and the role of hypercarnivory.
Published 2011-03-01“…The domestic cat (Felis catus) shows remarkable sensitivity to the adverse effects of phenolic drugs, including acetaminophen and aspirin, as well as structurally-related toxicants found in the diet and environment. …”
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8507
Perceptions of supervision and feedback in PaedCompenda, the competency-based, post-graduate curriculum in pediatrics (www.paedcompenda.de)
Published 2024-11-01“…Furthermore, the medical specialists who serve as trainers need to be specifically trained to know which approaches promote learning effectively.…”
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8508
Targeted Biofeedback Training to Improve Gait Parameters in Subacute Stroke Patients: A Single-Blind Randomized Controlled Trial
Published 2024-11-01“…However, a significant effect of such training was only observed with stance phase as the target parameter. …”
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8509
Role of Alpha Lipoic Acid in Ameliorating the Histological Alterations of Pituitary-Testicular Axis –induced by Hydrogen Peroxide in Rats
Published 2020-12-01“…In conclusion, the results indicated that alpha-lipoic acid mitigated pituitary-testicular dysfunctions induced by H2O2 through its antioxidant effects via scavenging free radicals.…”
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8510
The Neurological Significance of Abnormal Natural Killer Cell Activity in Chronic Toxigenic Mold Exposures
Published 2003-01-01“…Most likely, mycotoxins exert some rigorous effects on the circadian rhythmic processes resulting in sleep deprivation to which an acute and transient increase in NKC activity is observed. …”
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8511
Aloe ferox leaf gel extracts attenuate redox imbalance in oxidative renal injury and stimulates glucose uptake, whilst inhibiting key enzymes linked to diabetes and obesity
Published 2024-12-01“…Both metabolic disorders are linked to chronic adverse complications, which include kidney dysfunctions. Medicinal plants play a crucial role in traditional healthcare, especially in developing countries. …”
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8512
Innovative, Technology-Driven, Digital Tools for Managing Pediatric Urinary Incontinence: Scoping Review
Published 2025-05-01“…Meanwhile, digital interventions have already shown effectiveness in other pediatric health care areas. …”
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8513
Impact of PM2.5 Exposure on Reproductive Health and Sperm Functions in Mice from a High-Pollution Industrial Environment
Published 2025-05-01“…Conclusions Our study unequivocally demonstrated that being exposed to PM2.5, even at modest levels of air contaminants, can negatively impact the male reproductive system through causing biological impairments and cellular dysfunctions, including disturbances in sperm MMP, among other testicular effects. …”
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8514
Using a Smartphone Application to Strengthen Pelvic Floor and Manage Symptomatology of Female Track and Field Athletes: A Randomized Controlled Study
Published 2024-12-01“…Despite the high prevalence of pelvic floor (PF) dysfunctions in female athletes, help-seeking is low due to embarrassment and disinformation. …”
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8515
A Comparative Analysis of Cardiovascular Events Associated With Acalabrutinib Versus Ibrutinib in Chronic Lymphocytic Leukemia: Insights From a Global Federated Network
Published 2025-06-01“…Second‐generation BTK inhibitors (BTKi) such as acalabrutinib were developed to have greater selectivity for BTK to reduce off‐target effects and improve safety. Comparative real‐world data between ibrutinib and second‐generation BTKi are limited. …”
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8516
Differential Association Between Default Mode Network Connectivity and Attachment Styles in Healthy Individuals and Crohn's Disease Patients
Published 2025-06-01“…ABSTRACT Aim Crohn's disease (CD) is associated with psychological disorders and insecure attachment styles, potentially reflecting the long‐lasting disease effect. Although functional magnetic resonance imaging (fMRI) studies revealed differences in CD patients relative to HC, the brain properties underlying the attachment dimensions in CD remain scarcely investigated. …”
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8517
A structural genomics approach to investigate Dystrophin mutations and their impact on the molecular pathways of Duchenne muscular dystrophy
Published 2025-02-01“…Mutations, particularly single-point amino acid substitutions, can lead to dysfunctional Dystrophin, causing muscular dystrophies, with Duchenne muscular dystrophy (DMD) being the most severe form.ObjectiveThis study aimed to evaluate the effects of 184 single-point amino acid substitutions on the structure and function of Dystrophin using computational approaches.MethodsMany computational tools were used to predict the impact of amino acid substitutions on protein stability, solubility, and function. …”
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8518
Reduced T and NK Cell Activity in Glioblastoma Patients Correlates with TIM-3 and BAT3 Dysregulation
Published 2024-10-01“…Collectively, these data reveal that glioblastoma-mediated CD4<sup>+</sup> and CD8<sup>+</sup> T cell and NK cell suppression is due, at least in part, to dysregulated TIM-3 and BAT3 expression and the associated downstream immunoregulatory and dysfunctional effects.…”
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8519
Facilitating a high-quality dietary pattern induces shared microbial responses linking diet quality, blood pressure, and microbial sterol metabolism in caregiver-child dyads
Published 2022-12-01“…Low-resource individuals are at increased risk of obesity and cardiovascular disease (CVD), partially attributable to poor dietary patterns and dysfunctional microbiota. Dietary patterns in childhood play critical roles in physiological development and are shaped by caregivers, making caregiver-child dyads attractive targets for dietary interventions to reduce metabolic disease risk. …”
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8520
Analysis of BoDV-1 status, EEG resting-state alpha activity and pro-inflammatory cytokines in adults with and without major depressive disorder
Published 2024-11-01“…Most important, no group-dependent effect of BoDV-1 status on EEG resting-state activity had been observed. …”
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