Enriched Environment-Induced Neuroprotection against Cerebral Ischemia-Reperfusion Injury Might Be Mediated via Enhancing Autophagy Flux and Mitophagy Flux by Qi-Qi Zhang, Lu Luo, Mei-Xi Liu, Chuan-Jie Wang, Yi Wu, Ke-Wei Yu

“…In this study, we investigated whether and how autophagy and mitochondria quality control contribute to the protective effect of EE in the acute phase of cerebral ischemia–reperfusion injury. …”
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Silymarin Ameliorates Diabetes-Induced Proangiogenic Response in Brain Endothelial Cells through a GSK-3β Inhibition-Induced Reduction of VEGF Release by Ahmed Alhusban, Enaam Alkhazaleh, Tamam El-Elimat

“…Additionally, it was found to induce a dysfunctional angiogenic response in the brain that was attributed to oxidative stress. …”
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Imaging analytical technique to assess gastrointestinal motility in vivo using zebrafish larvae with diabetes mellitus-like traits. by Jessica C M Hui, Peng Du, Sarah E Webb, Julia Y H Liu, Man Piu Ngan, Zengbing Lu, Heidi S H Ng, Lingqing Yang, Aleena Khalid, Luping Liu, Zitong Li, Yingyi Deng, Dexuan Cui, John A Rudd

“…Hence, zebrafish are a useful model for studying GI dysfunctions due to DM and/or DM medication side-effects.…”
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Legislative Means Aimed at Stimulating Green Procurement in the Public Sector. A Critical Case Study of Romania by Ionel Bostan, Cristina Mihaela Lazăr, Nicoleta Asaloș

“…The special importance of the GPP, due to its favorable effects on the sustainable development, conservation / improvement of the environment, human health, etc., to which other positive social-economic implications are added, makes it a distinct subject of both EU strategies / policies, and the related legislative system. …”
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The crucial role of potassium ion channels in diabetes mellitus and its complications: A review by Xiangdong Yang, Yan Yang

“…Moreover, different drugs and treatments targeting the K+ channel may yield varying effects, offering promising prospects for preventing and managing diabetes and its related complications.…”
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The Role of Attachment in Refugees with Impaired Mental Health: A Systematic Review by Thomas Egger, Anna Buchheim, Manuela Gander

“…In children, insecure attachment was associated with parental mental health problems and dysfunctional parenting, whereas secure attachment buffered the effects of parental PTSD. …”
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Rehabilitation and Respiratory Expert Consensus on Full-Cycle Rehabilitation Assessment and Treatment for Older Adults with Lung Cancer by JIA Jie, CHEN Xin, HE Jing, DONG Anqin, DING Yipeng, LIAO Weijing, ZHENG Jiejiao, YU Binbin, CHEN Zuobing, FANG Yuan, YAO Liqing, ZHU Yiping, ZHU Jie, QIAN Jiayu

“…A comprehensive assessment of the patients' overall conditions and development of personalized rehabilitation treatment plans can effectively improve functional impairments, alleviate symptoms, and even prolong the survival time. …”
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RUSSIAN STRATEGIC CULTURE: INSIGHTS FROM THE FULL-SCALE WAR AGAINST UKRAINE by Метте Скак

“…The first year of war exposed a dysfunctional Russian strategic culture - a collapsing Blitzkrieg effort and a failure to prevail in the subsequent battle for Donbas. …”
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Age- and Gender-Related Differences in Renal Vascular Responses to Angiotensin II in Rats: The Role of the Mas Receptor by Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh

“…Therefore, the current study examined the effects of age and sex on systemic and renal vascular responses to graded doses of Ang II in Wistar rats with or without MasR antagonists (A779). …”
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Isokinetic Assessment of Shoulder Joint Strength Ratios in Male Recreational Weightlifters: A Cross-Sectional Study by Osama R. Abdelraouf, Marwa Y. Ebrahim, Amr A. Abdel-aziem, Soheir M. Abdel-Rahman, Ahmed S. Yamani, Ahmad A. El Askary

“…Isokinetic strength imbalance is a risk factor for movement dysfunctions and injuries related to shoulder complex. …”
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The role of microRNAs in learning and long-term memory by L. N. Grinkevich

“…The review presents summarized data on the effect of impaired microRNA biogenesis on long-term memory formation, including those associated with sleep deprivation. …”
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Ischemia of the Eye on the Background of Primary Hypothyroidism and Primary Thyrotoxicosis by V. G. Likhvantseva, E. V. Korosteleva

“…In patients with uncompensated thyroid dysfunctions, a violation of the blood supply to the anterior segment of the eye is observed, which can cause a low effect of antihypertensive monotherapy in the treatment of glaucoma.…”
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Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproduction. by Riyad El-Khoury, Eric Dufour, Malgorzata Rak, Nelina Ramanantsoa, Nicolas Grandchamp, Zsolt Csaba, Bertrand Duvillié, Paule Bénit, Jorge Gallego, Pierre Gressens, Chamsy Sarkis, Howard T Jacobs, Pierre Rustin

“…However, because of its energy-dissipating properties, AOX might produce deleterious effects of its own in mammals. Here we show that AOX can be safely expressed in the mouse (MitAOX), with major physiological parameters being unaffected. …”
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The PINK1-Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells. by Aaron V Bradshaw, Philip Campbell, Anthony H V Schapira, Huw R Morris, Jan-Willem Taanman

“…The ubiquitination of MFN1 and -2 in patient samples may therefore serve as a biomarker to determine the functional effects of PINK1 and PRKN mutations, and to screen idiopathic patients for potential mitophagy defects. …”
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Capturing trial-by-trial variability in behaviour: people with Parkinson’s disease exhibit a greater rate of short-term fluctuations in response times by Hayley J. MacDonald, Ole Bernt Fasmer, Olav T. Jønsi, Lin Sørensen

“…These novel results indicate that a similarity graph algorithm may be a sensitive tool to capture the rapidly varying changes in behaviour that result from dysfunctional dopamine bursting activity in PD.…”
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ER-induced PERK/TFEB cascade sequentially modulates mitochondrial dynamics during cranial suture expansion by Jingyi Cai, Ziyang Min, Chaoyuan Li, Zhihe Zhao, Jun Liu, Dian Jing

“…Abstract The effectiveness of cranial suture expansion therapy hinges on the timely and adequate regeneration of bone tissue in response to mechanical stimuli. …”
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“Between Scylla and Charybdis”: the influence of pregravid preparation on mental development of children born to mothers with epilepsy by A. S. Krasko, N. F. Mikhailova, I. V. Larina, V. A. Mikhailov, G. V. Odintsova

“…Achenbach), and attention deficit hyperactivity disorder and other behavioral dysfunctions questionnaire modified by N.N. Zavadenko (for children aged 5 years and older).Results. …”
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Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide im... by Sentaro Kaita, Yoshikazu Morishita, Kenta Kobayashi, Hiroshi Nomura

“…Abnormal spontaneous activity has, in fact, been associated with cognitive dysfunctions and psychiatric disorders. Given the cognitive improvement achieved with the use of H3 receptor inverse agonists/antagonists, we examined the effects of two inverse agonists/antagonists – thioperamide and pitolisant – on spontaneous cortical activity, using in vivo wide-field Ca2+ imaging. …”
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Leprosy and the adaptation of human toll-like receptor 1. by Sunny H Wong, Sailesh Gochhait, Dheeraj Malhotra, Fredrik H Pettersson, Yik Y Teo, Chiea C Khor, Anna Rautanen, Stephen J Chapman, Tara C Mills, Amit Srivastava, Amit Srivastava, Aleksey Rudko, Maxim B Freidin, Valery P Puzyrev, Shafat Ali, Shweta Aggarwal, Rupali Chopra, Belum S N Reddy, Vijay K Garg, Suchismita Roy, Sarah Meisner, Sunil K Hazra, Bibhuti Saha, Sian Floyd, Brendan J Keating, Cecilia Kim, Benjamin P Fairfax, Julian C Knight, Philip C Hill, Richard A Adegbola, Hakon Hakonarson, Paul E M Fine, Ramasamy M Pitchappan, Rameshwar N K Bamezai, Adrian V S Hill, Fredrik O Vannberg

“…Further population differentiation analysis shows that the TLR1 locus is extremely differentiated. The protective dysfunctional 602S allele is rare in Africa but expands to become the dominant allele among individuals of European descent. …”
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Transcranial Direct Current Stimulation over the Orbitofrontal Cortex Enhances Self-Reported Confidence but Reduces Metacognitive Sensitivity in a Perceptual Decision-Making Task by Daniele Saccenti, Andrea Stefano Moro, Gianmarco Salvetti, Sandra Sassaroli, Antonio Malgaroli, Jacopo Lamanna, Mattia Ferro

“…<b>Results</b>: Linear mixed-effects models showed that anodal tDCS over the left OFC reduced participants’ metacognitive sensitivity compared to sham stimulation, leaving perceptual decision-making accuracy unaffected. …”
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