Naringenin protects AlCl3/D-galactose induced neurotoxicity in rat model of AD via attenuation of acetylcholinesterase levels and inhibition of oxidative stress. by Saida Haider, Laraib Liaquat, Saara Ahmad, Zehra Batool, Rafat Ali Siddiqui, Saiqa Tabassum, Sidrah Shahzad, Sahar Rafiq, Narjis Naz

“…The objective of this study was to investigate the neuroprotective effects of naringenin (NAR) against AlCl3+D-gal induced AD-like symptoms in an animal model. …”
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The Limits of Legal Regulation of Military Relations by E. A. Glukhov

“…During military operations, these shortcomings not only reduce the effectiveness of control but are also likely to result in prevailing enemy's will, defeat, and unjustified casualties. …”
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P31 | MORPHOLOGICAL AND ULTRASTRUCTURAL MARKERS OF RADIATION-INDUCED ADIPOSE TISSUE DAMAGE

“…Hence, we applied morphological and ultrastructural analyses to a murine preclinical model of RT exposure to detect early markers of RT-induced WAT dysfunctions. Corresponding molecular profiling was also obtained by means of bulk RNA sequencing. …”
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Environmental Intervention: An Activist Idea or Legal Tool? An Analysis of the Possibilities of Environmental Protection under the Principle of Non-Intervention by Berkant Akkuş

“…The materials assembled for present discussion purposes support an alternative conclusion. The combined effect of the international law emphasis placed on State sovereignty, and a dysfunctional, inconsistent international community commitment to achieving actual climate change mitigation likely condemns to failure any environmental intervention measures that the UN might advance through proposed treaties or similar international agreements.…”
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Psychoneuroimmunoendocrinological and neuroanatomical basis of suicidal behavior: potential therapeutic strategies with a focus on transcranial magnetic stimulation (TMS) by Hesed Virto-Farfan, Gustavo E. Tafet

“…High-frequency TMS and accelerated theta-burst stimulation protocols demonstrate rapid therapeutic effects, though further research is needed to establish standardized treatment guidelines. …”
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The US Dollar as a Prerequisite for the Crisis Potential of the Global Monetary and Financial System by A. V. Kuznetsov

“…At the same time, modern research does not sufficiently present a comprehensive approach to studying the causes and consequences of the dysfunctionality of the current international monetary standard. …”
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Iranian postmenopausal women's perspectives on sexual satisfaction: A qualitative study. by Nasim Shahrahmani, Raheleh Babazadeh, Abbas Ebadi

“…Psychological factors, 4. Traces of dysfunctional married life, 5. Sexual satisfaction following positive sexual interactions, 6. …”
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Assessment of fully digitalized workflow for implant-prosthetic rehabilitation in temporomandibular disorders patients: A clinical study by Giuseppe Minervini, Rocco Franco, Salvatore Crimi, Manuele Basili, Saurabh Chaturvedi, Marco Cicciù, Alberto Bianchi, Gabriele Cervino

“…Digital flow is beneficial ei dysfunctional patients, not about improvements in temporomandibular symptoms but in times of operability and prosthetic retouching.…”
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A New Antibody–Cytokine Construct Targeting Natural Killer Cells: An Immunotherapeutic Approach to Chronic Lymphocytic Leukemia by Michela Flego, Mauro Andreotti, Francesca Romana Mauro, Maria Beatrice Arasi, Silvia Zamboni, Zuleika Michelini, Sara Pepe, Clementina Maria Galluzzo, Roberta Amici, Diego Moricoli, Chiara Mazzei, Alessandro Ascione, Alessandra Mallano

“…In chronic lymphocytic leukemia (CLL), natural killer (NK) cells show a dysfunctional phenotype that correlates with disease progression. …”
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A tailored phytosomes based nose-to-brain drug delivery strategy: Silver bullet for Alzheimer's disease by Xiao Yue, Haihua Guo, Guanlin Wang, Jieyun Li, Zizhao Zhai, Zeting Wang, Wenhao Wang, Ziyu Zhao, Xiao Xia, Chuangxin Chen, Yingtong Cui, Chuanbin Wu, Zhengwei Huang, Xuejuan Zhang

“…In the pharmacodynamic study based on AD rat model, GRg3@RHT exhibited obviously synergic effect, effectively break the vicious cycle of AD progression, ultimately markedly ameliorating learning and memory ability as well as behavioral dysfunctions, and delaying the neurodegenerative process associated with AD. …”
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Red blood cell aggregation within a blood clot causes platelet-independent clot shrinkage by Alina D. Peshkova, Ekaterina K. Rednikova, Rafael R. Khismatullin, Oleg V. Kim, Vladimir R. Muzykantov, Prashant K. Purohit, Rustem I. Litvinov, John W. Weisel

“…Blood clot shrinkage can be caused by RBCs alone, and this effect is because of the RBC aggregation driven mainly by osmotic depletion. …”
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Tea Consumption and Diabetes: A Comprehensive Pharmacological Review of Black, White, Green, Oolong, and Pu-erh Teas by Ochuko L. Erukainure, Chika I. Chukwuma, Jennifer Nambooze, Satyajit Tripathy, Veronica F. Salau, Kolawole Olofinsan, Akingbolabo D. Ogunlakin, Osaretin A. T. Ebuehi, Jeremiah O. Unuofin

“…Peer-reviewed articles published in “PubMed”, “Google Scholar”, and “ScienceDirect” from 2010 and beyond that reported the antidiabetic, antilipidemic, and digestive enzyme inhibitory effects of the selected tea types were identified. …”
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T CELL AGING IN RHEUMATOID ARTHRITIS by Maria Oubaid, Bushra tahreem, Toba Samreen, Javeria Parveen, Idress Khan

“…T-cell ageing and its effects on rheumatoid arthritis are discussed here, as well as how T-cells participate in tissue damage, acute and chronic inflammation, and the ageing process. …”
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Chronic Serotonergic Overstimulation Mimicking Panic Attacks in a Patient with Parkinson’s Disease Receiving Additional Antidepressant Treatment with Moclobemide by Marc Praetner, Timo Schiele, Lukas Werle, Janina Kuffer, Sandra Nischwitz, Martin E. Keck, Stefan Kloiber

“…Likely due to the delayed onset of adverse effects, physicians had difficulties in determining the pharmacologically induced serotonin toxicity. …”
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A clinical case of asymptomatic drug-induced thrombocytopenia by A. A. Zolotarev, E. A. Pyhtunova, O. Yu. Trifonova, S. I. Kseneva, V. V. Udut

“…The pathogenesis of such, drug-induced thrombocytopenia (DITP), is described as a consequence of direct cytotoxic effects of drug on megakaryocytes, which leads to increased platelet destruction in the bloodstream or dysfunctional thrombopoiesis. …”
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S1P receptor modulators affect the toxicity of amyloid β oligomers in microglial and neuronal cells by Iga Wieczorek, Robert P. Strosznajder

“…Abo cause mitochondrial dysfunctions leading to an imbalance between pro- and antiapoptotic proteins and finally to neuronal apoptosis. …”
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A red pomegranate fruit extract-based formula ameliorates anxiety/depression-like behaviors via enhancing serotonin (5-HT) synthesis in C57BL/6 male mice by Xiping Zhu, Dongxiao Sun-Waterhouse, Chun Cui

“…The RPFE formula (dose: 2.0, 1.5 or 1.0 mg/g day) reversed behavioral dysfunctions and body weight gain induced by chronic restraint stress combined with corticosterone injection in C57BL/6 male mice. …”
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Microtubule polymerization induced by iridium‐fullerene photosensitizers for cancer immunotherapy via dual‐reactive oxygen species regulation strategy by Xiao‐Xiao Chen, Kun Peng, Xi Chen, Zheng‐Yin Pan, Qing‐Hua Shen, Yu‐Yi Ling, Jian‐Zhang Zhao, Cai‐Ping Tan

“…Finally, Ir‐C601 exhibits promising photo‐immunotherapeutic effects both in vitro and in vivo. In all, we report here the first MT stabilizing photosensitizer performing through Type I/II photodynamic therapy pathways, which provides insights into the rational design of new photo‐immunotherapeutic agents targeting specific biomolecules.…”
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Enhanced Small Extracellular Vesicle Uptake by Activated Interneurons Improves Stroke Recovery in Mice by Mingjin Wang, Zhongwu Liu, Weida Wang, Michael Chopp, Michael Millman, Yanfeng Li, Pasquale Cepparulo, Amy Kemper, Chao Li, Li Zhang, Yi Zhang, Zheng Gang Zhang

“…Preclinical studies have shown that small extracellular vesicles (sEVs) have a therapeutic effect on stroke recovery. However, it is highly challenging to use sEVs to specifically target individual neuronal populations to enhance neuronal circuitry remodelling after stroke. …”
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Social and psychological determinants of positive mental health in engineering students by Fitri Ariyanti Abidin, Miryam Wedyaswari, Dhini Andriani, Indra Santosa Heriawan, Putu Getsha Pradnyan Rarasati Mudita, Syipa Husni Fadilah, Surya Cahyadi, Muhammad Haris Mahyuddin, Yogi Wibisono Budhi

“…Strengthening resilience and self-compassion effectively fosters positive mental health among engineering students. …”
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