Time Matters: Methane Inhalation Mitigates Mitochondrial and Organ Dysfunction in Advanced Experimental Sepsis by Levente Frigyes Gulácsi, Attila Rutai, László Juhász, Bálint László Czakó, Andrea Szabó, Mihály Boros, József Kaszaki, Marietta Zita Poles, Szabolcs Péter Tallósy

“…Sepsis induced significant organ dysfunction, impaired hemodynamics, reduced oxygen utilization, and decreased mitochondrial respiration. …”
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424 Liraglutide protects against microvascular dysfunction and sepsis-mediated inflammation and organ injury by David Aslaner, Brandon Baer, Jamie E. Meegan, Lorraine B. Ware, Julie A. Bastarache

“…. • To investigate the protective effects of liraglutide on microvascular dysfunction in a clinically relevant model of sepsis. • To provide evidence for the potential therapeutic use of GLP-1 receptor agonists in endothelial dysfunction in sepsis. …”
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Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction by Xiaolong Qu, Pan Yang, Li Jiao, Yuehui Yin

“…Background: Myocardial ischemia-reperfusion (I/R) injury and coronary microcirculation dysfunction (CMD) are observed in patients with myocardial infarction after vascular recanalization. …”
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High-Pressure Pneumoperitoneum Aggravates Surgery-Induced Neuroinflammation and Cognitive Dysfunction in Aged Mice by Bo Lu, Hui Yuan, Xiaojie Zhai, Xiaoyu Li, Jinling Qin, Junping Chen, Bo Meng

“…Postoperative cognitive dysfunction (POCD) is a common complication after surgery, especially in aged patients. …”
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Attentional dysfunction arises from right frontocentral and occipital network connectivity in Parkinson's disease by Isobel Timothea French, Kuo-Hsuan Chang, Wei-Kuang Liang, Wen-Sheng Chang, Yen-Shi Lo, Yi-Ru Wang, Mei-Ling Cheng, Norden E. Huang, Hsiu-Chuan Wu, Siew-Na Lim, Chiung-Mei Chen, Chi-Hung Juan

“…In Parkinson's disease (PD), the attentional network is impaired due to dysfunctional fronto-subcortical circuits connected to the basal ganglia, disrupting response selection and inhibition. …”
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Vasohibins in Health and Disease: From Angiogenesis to Tumorigenesis, Multiorgan Dysfunction, and Brain–Heart Remodeling by Ghulam Abbas, Annet Kirabo, Usama Ahmed, Jie Liu, Jidong Chen

“…These findings suggest the pleiotropic effects of VASHs in multiple organs and systems beyond angiogenesis. …”
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Association between male (in)fertility and telomeric dysfunction: a systematic review and meta-analysis by Sunny Kumar Jignesh Kumar Patel, Amit Roy Chowdhury, Sujata Kar, Purna Chandra Mohapatra, Birendranath Banerjee

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TRAIT ANXIETY AS A RISK FACOR OF COGNITIVE DYSFUNCTION IN PATIENTS AFTER MYOCARDIAL REVASCULARIZATION by O. A. Trubnikova, I. V. Tarasova, I. D. Syrova, A. S. Mamontova, O. V. Maleva, O. L. Barbarash

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High-fat diet impairs intermediate-term memory by autophagic-lysosomal dysfunction in Drosophila. by Tong Yue, Minrui Jiang, Kotomi Onuki, Motoyuki Itoh, Ayako Tonoki

“…Genetic enhancement of autophagic activity in neurons effectively restored ITM performance in the HFD-fed flies. …”
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Ocular and General Proprioception in Dyslexic Children: A Review of Their Diurnal and Nocturnal Dysfunctions and Their Repercussions by Patrick Quercia, Kalvin Chavet, Jérémie Gaveau

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PHOSPHODIESTERASE-5 INHIBITORS USE IN PATIENTS WITH ERECTILE DYSFUNCTION AND CARDIOVASCULAR DISEASE IN CLINICAL PRACTICE by M. N. Mamedov, G. G. Sharvadze, E. A. Poddubsky, A. K. Ausheva

“…About 150 million men worldwide and about 50% of men aged 40-88 y.o. in outpatient practice suffer from erectile dysfunction (ED). There is a linear relation between the age and ED rate. …”
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Sex differences in metabolic dysfunction-associated steatotic liver disease: a narrative review by Sae Kyung Joo, Won Kim

“…Women have a lower prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) than men. …”
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Prenatal and progressive coenzyme Q10 administration to mitigate muscle dysfunction in mitochondrial disease by Juan Diego Hernández‐Camacho, Cristina Vicente‐García, Lorena Ardila‐García, Ana Padilla‐Campos, Guillermo López‐Lluch, Carlos Santos‐Ocaña, Peter S. Zammit, Jaime J. Carvajal, Plácido Navas, Daniel J.M. Fernández‐Ayala

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Sympathetic motor neuron dysfunction is a missing link in age-associated sympathetic overactivity by Lizbeth de La Cruz, Derek Bui, Claudia M Moreno, Oscar Vivas

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Safety and Efficacy of Dapagliflozin in Patients With Systemic Right Ventricular Dysfunction: DAPA‐SRV Trial by Mathieu Albertini, Victor Waldmann, Pauline David, Alexis Barat, Antoine Legendre, Anne‐Solene Chaussade, Laurence Iserin, Magalie Ladouceur

“…Quality of life (91.5 versus 80.5, P<0.001), sRV function (fractional area change: 33% versus 28% [P=0.02]; global longitudinal strain: −13.1% versus −11.2% [P=0.04]) also improved. No significant side effects were observed. Conclusions This is the first study, to our knowledge, demonstrating the functional benefits and safety of dapagliflozin in symptomatic patients with sRV dysfunction under medical treatment with sacubitril/valsartan. …”
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Visual Dysfunctions in Mild Traumatic Brain Injury: A Focus on Accommodative System Impairments by Nawaf M. Almutairi

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Hormone correction of dysfunctional metabolic gene expression in stem cell-derived liver tissue by Alvile Kasarinaite, Maria Jimenez Ramos, Mariana Beltran-Sierra, Elena F. Sutherland, Pedro Arede Rei, Make Zhao, Ying Chi, Meryam Beniazza, Andrea Corsinotti, Timothy J. Kendall, Neil C. Henderson, Jonathan A. Fallowfield, Philippa T. K. Saunders, David C. Hay

“…Abstract The increase in metabolic dysfunction-associated steatotic liver disease (MASLD) and its progression to metabolic dysfunction-associated steatohepatitis (MASH) is a worldwide healthcare challenge. …”
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Endothelial dysfunction in acute renal injury in children with hemolytic-uremic syndrome (literature review) by E. V. Gunkova, A. A. Vyalkova, I. V. Zorin

“…It is promising to identify early and sensitive biomarkers of AKI in children with HUS for the development of new diagnostic approaches, which will optimize the early diagnosis and progression of renal damage in this category of patients. The study of the effect of endothelial dysfunction on the course and outcome of HUS is relevant and requires further research in this direction.…”
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Sexual Dysfunctions of HIV-Positive Men: Associated Factors, Pathophysiology Issues, and Clinical Management by Marco de Tubino Scanavino

“…Clinical trials of testosterone replacement therapy have shown the treatment to be beneficial to the improvement of sexual dysfunctions related to hypogonadism. However, there are not enough psychological intervention studies to make conclusions regarding the therapeutic effects of psychotherapy.…”
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Cognitive dysfunction and depression in chemotherapy patients: a cross-sectional study from Turkey by Elif Dinler, Deniz Kocamaz, Mürşide Özpineci, Sibel Polat Olca, Sema İçel, Mustafa Yıldırım

“…Socioeconomic status exacerbates these effects. Psychosocial interventions should be integrated into oncological rehabilitation.…”
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