I, as a Fault—Condemnation of Being and Power Dynamics in the Parent-Child Interaction by Rose Moreau Raguenes

“…In conclusion, the notion of condemnation acts of being—along with its descriptors—provides an effective framework that can be applied to reports and direct observations to help various professionals identify and assess transgressions and/or dysfunctions in authority relationships.…”
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Oxidative Stress in Critical Conditions and its Correction by N. A. Osipova, N. V. Edeleva, R. I. Yakubovskaya, Ye. R. Nemtsova, V. I. Chissov

“…The developed tactics of effective antioxidant therapy promotes optimization of the course of a rehabilitative period in patients after prior critical conditions and reduces the need for invasive hardware methods of correcting endotoxemia and MOD, which determines its economic expediency in addition to therapeutic one. …”
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CHA2DS2‐VASc score and prior oral anticoagulant use on endovascular treatment for acute ischemic stroke by Yukihiro Imaoka, Nice Ren, Soshiro Ogata, Hirotoshi Imamura, Yasuyuki Kaku, Koichi Arimura, Shogo Watanabe, Eri Kiyoshige, Kunihiro Nishimura, Syoji Kobashi, Masafumi Ihara, Kenji Kamiyama, Masafumi Morimoto, Tsuyoshi Ohta, Hidenori Endo, Yuji Matsumaru, Nobuyuki Sakai, Takanari Kitazono, Shigeru Fujimoto, Kuniaki Ogasawara, Koji Iihara, Close The Gap‐Stroke, J‐ASPECT Study Collaborators

“…Abstract Objective We evaluated the effect of CHA2DS2‐VASc score and prior use of oral anticoagulants (OACs) on endovascular treatment (EVT) in patients with acute ischemic stroke and atrial fibrillation (AF). …”
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Improvement of alexithymia in patients treated in mental health services for personality disorders: a longitudinal, observational study by Hanna Sayar, Theresa Wilberg, Theresa Wilberg, Ingeborg Ulltveit-Moe Eikenæs, Andreas Ekberg, Andreas Ekberg, Kai Leitemo, Katharina Teresa Enehaug Morken, Katharina Teresa Enehaug Morken, Eileen Oftedal, Eileen Oftedal, Siri Omvik, Dag Anders Ulvestad, Dag Anders Ulvestad, Geir Pedersen, Elfrida Hartveit Kvarstein, Elfrida Hartveit Kvarstein

“…Both alexithymia and measures of psychological functioning improved significantly during treatment with moderate effect sizes regardless of initial PD status. In total, 19% of the patients reported full remission of alexithymia.ConclusionAlexithymia is a common problem among patients with PDs and is associated with mental health difficulties and psychosocial dysfunction, with rates varying across PD type and severity. …”
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Sirtuin-3 activation by honokiol attenuated anesthesia/surgery-induced cognitive impairment and neuronal ferroptosis via inhibiting mitochondrial GPX4 acetylation by Lian Zeng, Pengchao Hu, Xuan Wang, Xudong Ding, Qingsong Wang, Li Luo, Yu Zhang, Mingyue Li, Yilin Zhao, Shiyong Li, Ailin Luo

“…HKL alleviated cognitive decline by inhibiting ferroptosis, evidenced by suppression of iron accumulation, oxidative stress, and mitochondrial dysfunction. In erastin-treated PC12 and HT22 cells, HKL effectively counteracted ferroptosis, which was abolished by GPX4 silencing. …”
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Integrated machine learning identifies disulfidptosis-related and ferroptosis-related genes to evaluate survival prognosis and treatment efficacy in kidney renal clear cell carcino... by Yuan Xiang, Zijian Zhou, Tong Mu, Shunyao Zhang, Lei Xie, Yajie Zhou, Wenxiong Zhang, Liuxiang Fu

“…Conclusions: Our DRFs-based prognostic model and nomogram effectively predict survival and guide treatment decisions.…”
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A next-generation system for smoke inhalation integrated with a breathing lung-on-chip to model human lung responses to cigarette exposure by Arunima Sengupta, Saskia Schmid, Noémie Grangier, Aurélien Dorn, Marco Hebestreit, Andreas Hugi, Kristína Žajdlíková, Anja Herbst, Paula Losada-Oliva, Heidi Ortolf-Wahl, Philippe Krebs, Janick D. Stucki, Vera van der Velpen, Jesus Perez-Gil, Tobias Krebs, Nina Hobi, Olivier T. Guenat

“…Animal models that inhale smoke nasally and have different lung physiology from humans may not accurately replicate cigarette smoke-induced health effects. Furthermore, traditional in vitro models fail to replicate the lung’s dynamic mechanical forces and realistic inhalation exposure patterns, limiting their relevance in preclinical research. …”
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Multilevel Assessment of Glycemic, Hormonal, and Oxidative Parameters in an Experimental Diabetic Female Rat Model by Iulian Tătaru, Ioannis Gardikiotis, Oana-Maria Dragostin, Luminita Confederat, Cerasela Gîrd, Alexandra-Simona Zamfir, Ionela Daniela Morariu, Carmen Lidia Chiţescu, Ancuța Dinu (Iacob), Liliana Costea Popescu, Carmen Lăcrămioara Zamfir

“…This study investigated the effects of alloxan-induced diabetes on hormonal status and oxidative stress in female Wistar rats. …”
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Impact of Protein Kinase C Activation and Monoclonal Antibodies on Immune Checkpoint Regulation and B Cell Function in Patients with Chronic Lymphocytic Leukemia by Aviwe Ntsethe, Phiwayinkosi Vusi Dludla, Bongani Brian Nkambule

“…<b>Background</b>: Chronic lymphocytic leukemia (CLL) is characterized by the proliferation of dysfunctional B cells, resulting in significant immune dysregulation. …”
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Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

“…It is now recognized that T cell functional state in the tumor microenvironment (TME) is a key determinant for effective antitumor immunity and immunotherapy. In addition to exhaustion, cellular senescence in tumor-infiltrating T cells (TILs) has recently been identified as an important T cell dysfunctional state induced by various malignant tumors. …”
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Qualitative analysis of family factors affecting emotion regulation in Iranian society: a qualitative content analysis by Peyman Hatamian, Kazem Rasoulzadeh Tabatabaei, Parviz Azadfallah, Jafar Hasani

“…Results: The analysis of findings led to two main categories of efficient communication processes in the family and dysfunctional communication processes in the family. …”
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The Interplay between Social Environment, Perceived Stress and Coping among Students: A Case of Malawi University of Business and Applied Sciences by Sufyan Rashid, Flemmings Fishani Ngwira, Janet Chikoja

“…These findings highlight the importance of reinforcing effective coping mechanisms and support networks to improve students' well-being and academic achievement. …”
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Adipose Tissue-Derived Extracellular Vesicles Loaded with miR-141-3p Regulate Obesity-Induced Insulin Resistance by Targeting Glycogen Synthesis and Gluconeogenesis by Wang Z, Ma T, Bai G, Fang Q, Ou B, Chen M, Xu P, Tian M, Xu A, Ma Y

“…This study aimed to investigate the regulatory effects of adipose tissue-derived EVs on obesity-induced hepatic insulin resistance and to elucidate the underlying molecular mechanisms by which EV-mediated signaling contributes to metabolic dysfunction.Methods: EVs with miR-141-3p knockout or overexpression were constructed and administered to both in vitro cell models and in vivo mouse models to investigate the regulatory role and underlying mechanisms of miR-141-3p-mediated adipose tissue-derived EVs in obesity-induced hepatic insulin resistance.Results: miR-141-3p is significantly upregulated in adipose tissue-derived EVs from high-fat diet (HFD)-fed mice, as well as in other obesity-related conditions. …”
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Mechanism of SLC1A5 Regulation of Glutamine Metabolism to Promote Ferroptosis Sensitivity in Endometriosis by Hui-Yu Ma, Huan-Yu Wu, Yu-Ting Xiang, Yu-Yin Liu, Jin Xie, Peng-Yu Cai, Bin Zhang, Yu-Hang Zhang, Ming-Xiu Wu

“…Overexpression of SLC1A5 enhanced sensitivity to ferroptosis, whereas SLC1A5 knockdown and NAC treatment reversed these effects. Mechanistically, c-Myc bound to the SLC1A5 promoter, forming positive feedback with ROS. …”
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A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression by Hongxia Zhao, Hongxia Zhao, Lingge Huang, Jian Liu, Min Feng, Yeqian Liu, Hong Li, Shan Gong, Chunming Chen, Shuiqing Zeng, Weiqiong Ren

“…These findings are consistent with the endothelial dysfunction and inflammatory responses observed in spontaneously hypertensive rats, which suggests that the lipopolysaccharide-induced RAECs model effectively mimics key pathological features of hypertension-related endothelial injury. …”
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IL-22 Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Epithelial Cell Apoptosis Associated with STAT3 Signalling by Zhu C, Chen J, Yan Z, Wang F, Sun Z, Liu Z, Li Y, Chen X, Bao Z, Li Q, Chen Z

“…Additionally, an in vitro model of lipopolysaccharide (LPS)-induced bronchial epithelial cell (BEAS-2B) apoptosis was established, and these cells were treated with or without recombinant IL-22 (rIL-22) to further evaluate the effect of IL-22 and the underlying mechanism.Results: The experimental results clearly confirmed that the levels of IL-22 were increased in the serum and lung tissue after CLP. …”
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Short-Term DMOG treatment rejuvenates senescent mesenchymal stem cells by enhancing mitochondrial function and mitophagy through the HIF-1α/BNIP3 pathway by Jiaxin Wen, Lingxian Yi, Lei Chen, Jinhan Xu, Yanmin Zhang, Qiheng Cheng, Hangyu Ping, Huanyu Wang, Feng Shuang, Wei Chai, Tujun Weng

“…Abstract Background Mesenchymal stem cells (MSCs) have potential for treating degenerative and immune diseases, but their clinical efficacy is limited by senescence, characterized by mitochondrial dysfunction, impaired mitophagy, and metabolic imbalance. …”
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Improvement in kidney damage resulting from stanozolol intramuscular injections in rats by Natural Cocoa Powder (NCP) administration by Daniel Odoom, Benjamin Arko-Boham, Kevin Kofi Adutwum-Ofosu, Richard Michael Blay, Saviour Kweku Adjenti, John Ahenkorah, Bismarck Afedo Hottor, Esther Dennis, Nii Koney-Kwaku Koney, Frederick Kwaku Addai

“…Natural cocoa powder (NCP) mitigated these effects, reducing PCT, DCT, and glomerular tuft volume densities by 92 %, 77 %, and 86 %, respectively. …”
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Algorithm for the provision of comprehensive psychotherapeutic support to women experiencing neuropsychiatric symptoms during rehabilitation following the treatment of malignant ne... by D. V. Blinov, A. G. Solopova, E. E. Achkasov, E. S. Akarachkova, O. V. Kotova, S. A. Akavova, V. N. Galkin, G. K. Bykovshchenko, L. N. Sandzhieva, D. I. Korabelnikov, T. A. Blbulyan, D. A. Petrenko, A. Yu. Vlasina

“…Chronic pain syndrome, distress, anxiety and depression, decreased self-esteem, sexual dysfunction and social maladjustment reduce quality of life (QoL) and require psychotherapeutic support.Objective: to create an algorithm for the provision of comprehensive psychotherapeutic support during rehabilitation following the treatment of reproductive system MNs and to evaluate its effect on QoL indicators in women with neuropsychiatric disorders.Material and methods. …”
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Leaky Gut Biomarkers as Predictors of Depression and Suicidal Risk: A Systematic Review and Meta-Analysis by Donato Morena, Matteo Lippi, Matteo Scopetti, Emanuela Turillazzi, Vittorio Fineschi

“…Data were independently extracted and reviewed by multiple observers. A random-effects model was employed for the analysis, and Hedge’s g was pooled for the effect size. …”
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