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7761
Linking Immunological Parameters and Recovery of Patient’s Motor and Cognitive Functions In The Acute Period of Ischemic Stroke
Published 2024-02-01“…There was a significant negative correlation between cognitive dysfunction and concentrations of Eotaxin-2/CCL24 (R=–0.378, P=0.00075), Gro-a/CXCL1 (R=–0.313, P=0.0035), and IP-10/CXCL1 (R=–0.214, P=0.00023), and between limited activities of daily living (IB) and concentrations of MPIF-1/CCL23 (R=–0.345, P=0.0024) and Gro-a/CXCL1 (R=–0.210, P=0.00001).Conclusion. …”
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7762
Clinical and genetic determinants of worse sexual experience in male patients with radiographic axial spondyloarthritis: a multimodal study
Published 2025-06-01“…The two-sample MR analysis demonstrated no causal effect of r-axSpA on the risk of ED (OR: 0.973; 95% CI: 0.824 to 1.149; p=0.749) based on the inverse variance weighted method. …”
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7763
An analysis of real-life data of infants born to mothers with autoimmune thyroiditis: do they need to be followed-up?
Published 2025-03-01“…Abstract Background Infants born to mothers with autoimmune thyroiditis (AT) could be at risk of developing thyroid dysfunction, and maternal anti-thyroid antibodies have been shown to have a clinical impact on offspring. …”
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7764
CLINICAL SIGNIFICANCE OF DETERMINING THE LEVEL OF THE BRAIN NATRIURETIC PEPTIDE FOR THE DIAGNOSIS OF HEART FAILURE OF COMORBID PATIENTS WITH CORONARY HEART DISEASE AND THYROTOXICOS...
Published 2017-09-01“…The hyperfunction of the thyroid body (gland), apparently, has a stimulating effect on the secretion of natriuretic peptides as the early marker of CHF. …”
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7765
Psychocorrection of psychic and psychopathological disorders in rheumatologic pathology
Published 2020-08-01“…The significant influence of psychocorrection on the psychic and somatic condition has been observed both in improving the patients’ health and lowering the mental disorders severity. The effectiveness of follow-up correction has been confirmed in 76.0 % of patients, a significant improvement – in 28.0 % and a moderate improvement – in 48.0 % of patients.…”
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7766
Corneal sensory nerve loss induced by repeated subconjunctival and topical bupivacaine disrupts tear secretion and enhances bacterial adhesion via neuropeptide modulation.
Published 2025-01-01“…All assessments, including nerve depletion effects on tear production, bacterial adhesion, and neuropeptide loss, were conducted on day 15 post-bupivacaine treatment.…”
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7767
Pirfenidone reduces ovarian fibrosis and improves PCOS in letrozole-induced rat model
Published 2025-06-01“…This study investigated whether pirfenidone (PFD), an antifibrotic agent, could improve ovarian dysfunction in a letrozole-induced PCOS rat model. Forty-two female Wistar albino rats were divided into six groups (n=7 each): control, PFD, PCOS, PCOS/PFD, PCOS/combined oral contraceptives (COC), and PCOS/PFD/COC. …”
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7768
The quality of life in anemic patients with chronic heart failure, depending on the presence or absence of chronic kidney disease
Published 2013-06-01“…Color level had a significant effect on the physical, functional, and emotional well-being in patients with chronic heart failure, chronic kidney disease and anemia, as well as the level of social and family relationships in patients with anemia, developed on a base of chronic heart failure without chronic kidney disease.…”
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7769
Influence of the metabolic and inflammatory profile in patients with frozen shoulder – systematic review and meta-analysis
Published 2025-05-01“…Conclusion This meta-analysis highlights the role of metabolic dysfunction and chronic inflammation in the pathogenesis of FS. …”
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7770
Sjögren’s syndrome is associated with a reduction in the surface area of the right caudal anterior cingulate gyrus
Published 2025-07-01“…The identified genes and cell types provide insights into the mechanisms underlying the effects of SS on brain structure.…”
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7771
Independent role of two novel abdominal fat indicators in chronic diarrhoea
Published 2025-07-01“…BackgroundStudies have confirmed that obesity is an antecedent of chronic diarrhoea, and new evidence suggests that visceral fat accumulation may play a more critical role than total body fat in intestinal dysfunction and the development of chronic diarrhoea. …”
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7772
Coherence Analysis of Cardiovascular Signals for Detecting Early Diabetic Cardiac Autonomic Neuropathy: Insights into Glycemic Control
Published 2025-06-01“…<b>Conclusions:</b> Coherence analysis provides valuable insights into autonomic dysfunction in early diabetes. The significant reduction in LF<sub>Coh</sub> in early diabetes supports its role as a potential marker for CAN. …”
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7773
Executive Functions, Anxiety, Social Participation and Quality of Life in Children with Migraine During COVID-19
Published 2025-03-01“…The COVID-19 pandemic had a less deleterious effect on migraine patients compared to the healthy control group. …”
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7774
Evaluating the safety and feasibility of remote ischemic conditioning for slowing cognitive decline in mild Alzheimer’s dementia
Published 2025-06-01“…ObjectiveAlzheimer’s disease (AD) is characterized by complex pathological mechanisms involving neuroinflammation, oxidative stress, and vascular dysfunction. Remote Ischemic Conditioning (RIC) has shown potential in addressing these pathways by improving cerebral blood flow, reducing oxidative stress, and modulating inflammatory responses. …”
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7775
The mediating role of daily living ability and sleep in depression and cognitive function based on a structural equation model
Published 2025-04-01“…Abstract Background The incidence of depression and cognitive dysfunction is high in the elderly population, which incurs serious social burden. …”
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7776
Kasabach-Merritt syndrome in an adult treated by embolization prior to liver transplantation: a case report.
Published 2025-04-01“…When there is severe liver dysfunction or recurrent bleeding, liver transplantation should be considered. …”
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7777
HLA-F regulates the proliferation of trophoblast via PKM2-dependent glycolysis in the pathogenesis of preeclampsia
Published 2025-04-01“…This study aimed to analyze the effect and mechanism of HLA-F on the proliferation of trophoblast and the underlying mechanism of reduced HLA-F involved in preeclampsia. …”
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7778
High-fat diet mouse model receiving L-glucose supplementations propagates liver injury
Published 2024-12-01“…Background and aimsLimited data link manufactured sweeteners impact on metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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7779
Restoring endogenous Dlg4/PSD95 expression by an artificial transcription factor ameliorates cognitive and motor learning deficits in the R6/2 mouse model of Huntington’s disease
Published 2025-06-01“…HD is characterized by motor dysfunction and cognitive decline. The pathophysiology of HD begins in cortico-striatal circuits and later spreads to other brain regions, notably the hippocampus. …”
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7780
GLUT1-mediated HMGB1 O-GlcNAcylation drives hyperglycemia-Induced neutrophil extracellular trap networks formation via TLR4 signaling and exacerbates fibroblast inflammation
Published 2025-05-01“…Mechanistically, GLUT1 knockdown reduced HMGB1 O-GlcNAcylation and reversed NET-induced fibroblast dysfunction. Our findings provide direct evidence that hyperglycemia enhances GLUT1 expression and activity, driving HMGB1 O-GlcNAcylation to maintain NETs formation through TLR4, which promotes fibroblast inflammatory injury. …”
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