Impaired Vigilance in Patients with Narcolepsy Type 1: A Psychomotor Vigilance Task Study by Yu J, Zhou Y, Han X, Li Z, Chen F, Zhang L

“…The patients also had a greater tendency for daytime sleepiness and poorer nighttime sleep quality, higher depression and impulsiveness scores, and more severe cognitive dysfunction. PVT performance was better in the healthy controls than in patients with NT1. …”
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Voices from Iraq: Emerging Clinical Evidence and Implications for Global Health Equity by Oluwatosin Olu-Abiodun, Redha Abdalredha, Aderinsola Faturoti, Olumide Abiodun

“…Despite facing important widespread challenges, Iraqi researchers are delivering critical and relevant insights in six key areas: (1) Gender-specific biochemical markers in rheumatoid arthritis demonstrate higher levels of uric acid and alkaline phosphatase; (2) The Bristow-Latarjet technique for treating shoulder instability achieves an impressive success rate of 75%, even under resource constraints; (3) The epidemiology of traumatic brain injuries in conflict areas reveals that blast injuries account for a staggering 39.5% of cases, whereas conservative management increases mortality risk greatly (OR=20.03); (4) Research on the hepatoprotective effects of Tribulus terrestris extract shows promise against methotrexate toxicity, offering affordable options for managing liver damage due to chemotherapy; (5) A connection between Tetraiodothyronine (T4) hormone levels and higher instances of miscarriage, preeclampsia, intrauterine growth restriction, and low birth weight; and (6) Enhanced levels of inflammatory markers (PCT, TNF-α, IL-6) combined with low zinc levels can predict disease progression, immune dysfunction, and nutritional deficiencies among lymphoma patients in resource-limited settings. …”
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Sacubitril/Valsartan attenuates progression of diabetic cardiomyopathy through immunomodulation properties: an opportunity to prevent progressive disease by Narainrit Karuna, Lauren Kerrigan, Kevin Edgar, Mark Ledwidge, Ken McDonald, David J. Grieve, Chris J. Watson

“…Methods and results Sacubitril/Valsartan effectively reduced plasma neprilysin activity in both diabetic patients with pre-clinical HFpEF from the PARABLE trial (baseline (Val n = 25; Sac/Val n = 35) and 3 months after treatment (Val n = 21/25; Sac/Val n = 33/35)) and DbCM (high-fat diet and streptozotocin) mice. …”
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Factors affecting cadmium toxicity to rice germinated in soils collected from downstream areas of abandoned zinc mines by P. Chanpiwat, A. Numprasanthai

“…These cultivated rice grains are consumed by local residents and have increased the risk of renal dysfunction in residents. Decreasing negative health effects by reducing cadmium accumulation in rice should be considered. …”
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The Risk of New-Onset Atrial Fibrillation in Patients With Conduction System Pacing Versus Right Ventricular Pacing: A Meta-Analysis by Tingwen Gao, Zhaofeng Li, Wei Li, Xue Wang, Xinxing Xie

“…In the subgroup analysis, patients with atrioventricular block (AVB) tended to benefit more from CSP than those with sinus node dysfunction (SND) or AVB (p = 0.06 for RR; p = 0.12 for OR). …”
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Exploring the health complications of female genital mutilation through a systematic review and meta-analysis by Christina Pallitto, Fernando Ruiz-Vallejo, Vernon Mochache, Karin Stein, Joshua P. Vogel, Max Petzold

“…., immediate, obstetric & neonatal, gynecological, urological, sexual and mental). Random effects meta-analysis was conducted by health condition and FGM type. …”
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Perioperative acute kidney injury in surgical treatment of renal cancer: pathogenesis, therapy of early and late complications by S. V. Popov, R. G. Guseynov, Ye. V. Pomeshkin, K. V. Sivak, V. V. Perepelitsa, K.  A. Nadein, N. S. Bunenkov, A. S. Ulitina

“…The main directions of medical and preventive measures in patients with acute kidney injury should be considered: 1) the fastest possible elimination or minimization of the effect of tumor tissue; 2) control and correction of life‑threatening complications of renal dysfunction (hyperhydration, electrolyte balance disorders (hyperkalemia), acid‑base state, uremic intoxication). …”
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PERFORMED FACTORS IN THE REHABILITATION OF CARDIAC PATIENTS ON AN OUTPATIENT BASIS by О.I. Tokarenko, O.V. Kovaleva, A.A. Kovaleva, O.O. Tokarenko

“…Such a problem was observed due to dysfunction of the autonomic nervous system, which is an integral companion of the pathology of the gastrointestinal tract. …”
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Prevalence and Progression of Cognitive Impairment in Atrial Fibrillation Patients after Treatment with Catheter Ablation or Drug Therapy by Tina S. Tischer, Daniel Nitschke, Isabelle Krause, Günther Kundt, Alper Öner, Giuseppe D’Ancona, Erdal Şafak, Hüseyin Ince, Jasmin Ortak, Evren Caglayan

“…In atrial fibrillation (AF) patients, the effect of catheter ablation or drug therapy on cognition is currently not well investigated. …”
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The role of sex differences in cardiovascular, metabolic, and immune functions in health and disease: a review for “Sex Differences in Health Awareness Day” by Lana McClements, Alexandra Kautzky-Willer, Georgios Kararigas, Sofia B. Ahmed, John N. Stallone

“…There is a growing awareness that metabolic and immune dysfunction are intimately tied to the development of cardiovascular diseases. …”
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Comparative evaluation of SGLT-2i and GLP-1RA neuroprotective properties in type 2 diabetic patients by A. V. Murasheva, T. L. Karonova, O. S. Fuks, N. V. Timkina, A. D. Fedotova, E. N. Grineva, E. V. Shlyakhto

“…BACKGROUND: Chronic brain dyscirculation (CBD) is a common type 2 diabetes mellitus (DM) complication that leads to the cognitive dysfunction. Glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter type 2 inhibitors (SGLT-2i) can reduce the stroke risk but their effect on CBD is not fully studied.AIM: To study and to compare the effect of SGLT-2i of various selectivity and GLP-1RA on the biochemical and functional parameters of CNS damage in patients with type 2 DM.MATERIALS AND METHODS: Type 2 diabetic patients with target HbA1c level on metformin monotherapy were included in “MET” group (n=43), with non-target HbA1c were divided into groups: “MET+EMPA”, n=47, (empagliflozin therapy), “MET+CANA”, n=41, (canagliflozin therapy), “MET+GLP-1RA”, n=66 (therapy with injectable GLP-1RA). …”
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A cluster randomized trial of a Multicomponent Clinical Care Pathway (MCCP) to improve MASLD diagnosis and management in primary care: study protocol by Kyler M. Godwin, Larissa Grigoryan, Aaron P. Thrift, Hao Duong, Fasiha Kanwal, Traber Giardina, Himabindu Kadiyala, Andrew Zimolzak, Kavish R. Patidar, Hashem B. El-Serag

“…Abstract Background Metabolic dysfunction associated steatotic liver disease (MASLD) is the most common chronic liver disorder in the world. …”
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Qiangyang decoction attenuates ischemia/reperfusion-induced cardiomyocyte ferroptosis via ULK1/KEAP1/Nrf2 axis by Jing Wang, Wan Cai, Jingxuan Chen, Wenjin Wang, Wentao Fu, Wen Ge, Hao Chi

“…Background: Myocardial ischemia-reperfusion (I/R) induced cardiomyocyte death is a major cause of cardiac dysfunction and fibrosis. Ferroptosis of cardiomyocytes has been demonstrated to contribute to I/R induced injury. …”
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Saccadometry Findings in Migraine Patients Without Aura by Asya Fatma Men, Aysenur Kucuk Ceyhan, Mustafa Men, Reyhan Sürmeli

“…Objective This study aims to evaluate prosaccade and antisaccade eye movements in patients with migraine without aura (MWOA) and determine whether the saccadometry test is an effective tool for identifying cognitive control and executive dysfunctions in these individuals. …”
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Enzyme replacement therapy for the treatment of late onset Pompe disease: A systematic review and network meta-analysis by Mark Corbett, Chinyereugo Umemneku-Chikere, Sarah Nevitt, Nyanar Jasmine Deng, Matthew Walton, Helen Fulbright, Chong Yew Tan, Robin Lachmann, Rachel Churchill, Robert Hodgson

“…LOPD causes progressive muscle dysfunction and damage, leading to significant morbidity and early mortality. …”
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Subchronic cyanuric acid treatment impairs spatial flexible behavior in female adolescent rats through depressing GluN2B-dependent neuronal and synaptic function by Wei Sun, Haiyang Yu, Xiaoliang Li, Yiwen Wan, Yazi Mei, Yang Yang, Lei An

“…Our findings provide the first evidence that CA can exert neurotoxic effects on females and certify that one of the potential mechanisms for neuronal and synaptic dysfunction is the GluN2B-mediated signaling pathway.…”
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Ketogenic diet in treating sepsis-related acquired weakness: is it friend or foe? by Yanmei Miao, Leiyu Xie, Shaolin Chen, Xiaoming Zhang, Wenjie Liu, Peng Xie, Peng Xie

“…Using the method of induction and summary, analyze the effect and mechanism of KD on SAW.ResultsCompared with early nutrition, KD has a more protective effect on SAW, but its mechanism is complex. …”
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Associations of MAFLD subtypes and air pollutants with multi-system morbidity and all-cause mortality: A prospective cohort study by Jingyi Zhang, Shanshan Ran, Shengtao Wei, Fei Tian, Lan Chen, Zijun Yang, Ge Chen, Hualiang Lin

“…Background: Metabolic dysfunction-associated fatty liver disease (MAFLD) and air pollution are both significant health concerns. …”
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ANALYSIS OF HEART RATE VARIABILITY IN PATIENTS WITH PERSISTENT ATRIAL FIBRILLATION by M. I. Fushtey, O. V. Soloviov, E. V. Sid’

“…In the presence of the effect of β-blocker treatment in patients with persistent AF, the increase in HRV parameters should be considered as a beneficial effect of β-blockers in the SNC. …”
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Beneficial Role of Imeglimin as Add-on Drug with other Oral Hypoglycaemic Agents for Patients with Type 2 Diabetes: A Single centre Prospective Interventional Study by Naima Parveen, Sachin Chittawar

“…By addressing insulin resistance and β-cell dysfunction, imeglimin emerges as a dual-action therapy tailored for patients who are hesitant to initiate insulin. …”
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