C3+ cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway by Zhenxiong Zhao, Si Xiong, Jianpeng Gao, Yingjing Zhang, Ergang Guo, Yakai Huang

“…Furthermore, C3+ CAFs were associated with immunosuppressive effects and an immune-evasive microenvironment marked by CD8 + T cell dysfunction. …”
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Association of Risk-Taking Behaviors, Vestibular Provocation and Action Boundary Perception Following Sport-Related Concussion in Adolescents by Shawn R. Eagle, Anthony P. Kontos, Shawn D. Flanagan, Christopher Connaboy

“…<b>Methods</b>: This study utilized a cross-sectional design to evaluate the early effects of concussion on 12–18-year-old adolescents (n = 47) recruited from a concussion specialty clinic at their presenting clinical appointment. …”
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Hypoxic mesenchymal stem cell-derived exosomal circDennd2a regulates granulosa cell glycolysis by interacting with LDHA by Wenxin Li, Minjun Lu, Junyu Shang, Jiamin Zhou, Li Lin, Yueqin Liu, Dan Zhao, Xiaolan Zhu

“…Abstract Background Premature ovarian insufficiency (POI) is an ovarian dysfunction disorder that significantly impacts female fertility. …”
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Transcriptional Profiling Underscores the Role of Preprocurement Allograft Metabolism and Innate Immune Status on Outcomes in Human Liver Transplantation by Joohyun Kim, MD, PhD, Michael T. Zimmermann, PhD, Angela J. Mathison, PhD, Gwen Lomberk, PhD, Raul Urrutia, MD, Johnny C. Hong, MD

“…Objective:. The adverse effects of ischemia-reperfusion injury (IRI) remain a principal barrier to a successful outcome after lifesaving orthotopic liver transplantation (OLT). …”
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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…While increased MITF expression in MDSCs promoted breast cancer progression and CD4+ or CD8+ T-cell dysfunction, decreased MITF expression in MDSCs suppressed tumor progression and enhanced T-cell activation. …”
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Nonoperative Care Versus Surgery for Degenerative Cervical Myelopathy by Markian Pahuta, MD, PhD, FRCSC, Mohamed Sarraj, MD, Jason Busse, DC, PhD, Daipayan Guha, MD, PhD, FRCSC, Mohit Bhandari, MD, PhD, FRCSC

“…Degenerative cervical myelopathy (DCM) occurs when spondylotic changes compress the spinal cord and cause neurologic dysfunction. Because of a lack of comparative data on nonoperative care versus surgery for DCM, it has been difficult to support patients through the shared decision-making process regarding treatment options. …”
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Cognitive recovery of post critical care patients with and without COVID-19: differences and similarities, an observational study by Anna Gorsler, Christiana Franke, Anneke Quitschau, Nadine Külzow

“…Significant gains until discharge were only revealed for information processing speed in both groups (main effect visit, mean difference [95%CI] − 7.5 [− 13.1, − 2.0]). …”
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One-stage buccal two-flap urethroplasty using the Kulkarni technique for extended anterior urethral strictures by M. I. Katibov, M. M. Alibekov, Z. M. Magomedov, A. M. Abdulkhalimov, V. G. Aydamirov

“…Evaluation of the effectiveness of one-stage buccal urethroplasty according to the Kulkarni technique using two flaps for extended anterior urethral strictures.Materials and methods. …”
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Introducing a Novel Personalized Microbiome-Based Treatment for Inflammatory Bowel Disease: Results from NostraBiome’s Internal Validation Study by Adrian Goldiș, Radu Dragomir, Marina Adriana Mercioni, Christian Goldiș, Diana Sirca, Ileana Enatescu, Oana Belei

“…Notably, patients on anti-TNF biologics showed enhanced response rates, suggesting potential synergistic effects between microbiome modulation and biologic therapy. …”
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Surgical outcomes of women undergoing radical resection of deep endometriosis of the sacral plexus: A prospective cohort study by Gernot Hudelist, Ezgi Darici Kurt, Gábor Szabó, Dominika Miklos, Theresa Hudelist, Attila Bokor

“…However, there is only limited data on the effects of surgery on pain and neurological symptoms. …”
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Impaired DNAJB2 Response to Heat Shock in Fibroblasts from a Neuropathy Patient with <i>DNAJB2/HSJ1</i> Mutation: Cystamine as a Potential Therapeutic Intervention by Raj Kumar Pradhan, Nikolas G. Kinney, Brigid K. Jensen, Hristelina Ilieva

“…<b>Background and Objectives:</b> Neuropathy is a debilitating disorder characterized by peripheral nerve dysfunction and damage to sensory, motor, and autonomic neurons and their axons. …”
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Construction and validation of HBV-ACLF bacterial infection diagnosis model based on machine learning by Neng Wang, Shuai Tao, Liang Chen

“…SHAP analysis revealed a unique characteristic driving the risk of bacterial infection, including apolipoprotein A1, complement C3, D-dimer, C-reactive protein (CRP), total bilirubin (TBIL), and international normalized ratio (INR), which reflected the synergistic effect of markers of inflammation, coagulation, and liver dysfunction. …”
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Influences of Gait Training with Knee–Ankle–Foot Orthosis on Gait Ability and Independence in Severe Hemiplegia and Pusher Behavior with Unilateral Spatial Neglect Following Stroke... by Kota Sawa, Miko Tamura, Saori Arai

“…ABSTRACT Background Orthotic therapy is crucial for post‐stroke patients with severe motor paralysis and higher brain dysfunction, including pushers and unilateral spatial neglect (USN). …”
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Comparative association between NAFLD and MAFLD with cardiovascular events and mortality: Evidence from observational studies. by Taoli Fu, Jitao Ling, Huilei Zhao, Kaixin Lin, You Deng, Miao Zhang, Xinrui Qi, Peng Yu, Weichun Lin, Xiao Liu

“…<h4>Background</h4>Nonalcoholic fatty liver disease (NAFLD) and metabolic dysfunction-associated fatty liver disease (MAFLD) are increasingly recognized as multisystemic conditions with significant extrahepatic manifestations. …”
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The contribution of modifiable risk factors to the formation of cardiovascular remodelling and vegetative balance in patients with essential hypertension by V. V. Syvolap, O. V. Vizir-Tronova

“…The presence of any risk factor in EH patients has an unidirectional negative effect on the structural, geometric and functional alteration of the heart, is associated with a tendency to reduce blood flow in all of extra- and intracranial vessels. …”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…This provides negative effect on terms of esophageal erosions healing.…”
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Comparison of dyspareunia using female sexual index score in 3-month, 6-month, and 12-month postpartum after vaginal delivery and cesarean section: meta-analysis by Eighty Mardiyan Kurniawati, Zettira Maulida Prasha, Hari Paraton

“…There is a change in mindset due to the change in women’s role, let alone the perception stating that cesarean delivery can decrease the risk of having pelvic floor dysfunction and maintain the sexual functions. Therefore, women think that cesarean delivery is a good choice for delivery, even it has no indications. …”
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RADIATION-INDUCED TOXICITY IN BREAST CANCER PATIENTS TREATED WITH TRASTUZUMAB-BASED CHEMOTHERAPY by R. Yu. Karabut, A. V. Vazhenin, E. Y. Mozerova, M. M. Sarycheva, A. A. Lozhkov, A. Yu. Maksimovskaya, D. M. Timokhina

“…Radiation-induced side effects were assessed using the rtog/eortc scoring criteria. …”
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Nanoparticles from grape seed extract inhibit inflammatory cytokines and ameliorate CCl4-induced hepatotoxicity by Neveen Adel Madbouly, Doaa Mohammad Ali, Alyaa Ahmed Farid

“…The current study was conducted to survey the antioxidant effect of grape seeds extract nanoparticles (GS extract NPs) against CCl4-induced oxidative stress, hepatic dysfunction and inflammatory changes. …”
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HIV Infection and Antiretroviral Therapy Impair Liver Function in People Living with HIV: Systematic Review and Meta-Analysis by Kay-Lee E. Strauss, Wendy N. Phoswa, Sidney Hanser, Kabelo Mokgalaboni

“…This systematic review and meta-analysis assess the effects of HIV infection and ART on liver function in PLWH. …”
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