Suggested Topics within your search.
Suggested Topics within your search.
-
7161
Neurocognitive functioning over the course of STAIR Narrative Therapy for ICD-11 complex PTSD
Published 2025-12-01“…Given the different symptom features and potentially different neural profiles between ICD-11 complex PTSD (CPTSD) and PTSD, neurocognitive dysfunction is considered an even more serious problem in CPTSD. …”
Get full text
Article -
7162
Gut Microbiome dysbiosis and immune activation correlate with somatic and neuropsychiatric symptoms in COVID-19 patients
Published 2025-03-01“…Gut dysbiosis, an imbalance in the gut microbiome, has been implicated in immune dysfunction and chronic inflammation in COVID-19 patients. …”
Get full text
Article -
7163
The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment
Published 2025-01-01“…We performed a comprehensive analysis of gene function enrichment between the two populations at risk, thoroughly examined their immune microenvironment characteristics, and assessed the effectiveness of immunotherapy. Finally, the function of CDKN3 in LUAD was verified by in vitro experiments. …”
Get full text
Article -
7164
FCN3 Can Serve as A Potential Biomarker for Prognosis and Immunotherapy of Lung Squamous Cell Carcinoma
Published 2025-02-01“…The complex immune escape mechanism limits the effectiveness of immunotherapy. Ficolin-3 (FCN3) is a crucial immunomodulatory molecule that regulates immune escape by remodeling the tumor microenvironment. …”
Get full text
Article -
7165
Sensory modulation difficulties and complex PTSD among child abuse survivors
Published 2025-12-01“…Evidence suggests that CA may also result in sensory modulation dysfunction, which is related to posttraumatic distress. …”
Get full text
Article -
7166
Comparison of 7 surgical interventions for recurrent lumbar disc herniation: A network meta-analysis and systematic review.
Published 2025-01-01“…The Markov chain Monte Carlo methods were used to perform a hierarchical Bayesian NMA in R version 4.3.3 using a random effects consistency model. The assessing outcomes were pain intensity, disability, complications and recurrence.…”
Get full text
Article -
7167
Liver biomarkers as predictors of prognosis in heart failure with preserved ejection fraction: a systematic review and meta-analysis
Published 2025-04-01“…Hazard ratios (HR) were pooled using a random-effects model, and heterogeneity was assessed using the I² statistic. …”
Get full text
Article -
7168
Cardiac Manifestations and Emerging Biomarkers in Multisystem Inflammatory Syndrome in Children (MIS-C): A Systematic Review and Meta-Analysis
Published 2025-05-01“…Meta-analyses were performed for NT-proBNP and troponin using random-effects models. Descriptive profiling was applied to emerging biomarkers. …”
Get full text
Article -
7169
A complex role of chromogranin A and its peptides in inflammation, autoimmunity, and infections
Published 2025-04-01“…Conversely, PST is reported to stimulate proinflammatory M1 macrophage polarization and Th1 lymphocyte response. Thus, the final effects of CgA in inflammation may depend on its cleavage pattern. …”
Get full text
Article -
7170
Home-based exercise for chemotherapy-induced peripheral neuropathy: a feasibility study
Published 2025-07-01“…Abstract Background Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect of chemotherapy that affects the sensory, motor, and autonomic nerves. …”
Get full text
Article -
7171
Cross-species comparisons between pigs and mice reveal conserved sex-specific intraspinal inflammatory responses after spinal cord injury
Published 2025-01-01“…The purpose of this study was to evaluate the effect of sex on inflammation and outcomes in a pig thoracic contusion/compression SCI model. …”
Get full text
Article -
7172
Changes in the cytokine response in the hypothlamus of animals under the influence of chronic social stress: RNAseq data
Published 2024-07-01“…It was confirmed the key role of these genes in the development of dysfunction of cytokines in the brain.…”
Get full text
Article -
7173
From signaling pathways to clinical trials: mesenchymal stem cells as multimodal regenerative architects in liver cirrhosis therapy
Published 2025-08-01“…Abstract Liver cirrhosis, a chronic disease distinguished by extensive scarring in the liver, results in liver dysfunction and fatal complications such as portal hypertension and liver cancer. …”
Get full text
Article -
7174
Development and validation of the reported outcome scale for patients with lumbar disc herniation
Published 2025-12-01“…Validity was examined through content and criterion-related validity analyses.Results The final PRO scale comprised 29 items across five dimensions: Physical Symptoms (5), Physical Dysfunction (11), Psychological emotion (5), Social Adaptation (4), and Therapeutic Effect (4), explaining 69.07% of total variance. …”
Get full text
Article -
7175
Retrospective cohort study based on the MIMIC-IV database: analysis of factors influencing all-cause mortality at 30 days, 90 days, 1 year, and 3 years in patients with different t...
Published 2025-01-01“…The predictive model constructed effectively assesses mortality risks in stroke patients, offering support for future clinical practice.…”
Get full text
Article -
7176
The efficacy and safety of mirabegron and α-adrenergic receptor antagonist in the treatment of distal ureteral stones: a systematic review and meta-analysis
Published 2025-03-01“…Mirabegron also had fewer side effects like headache (RR = 0.34; 95% CI = 0.13–0.87; P = 0.02) and orthostatic hypotension (RR = 0.11; 95% CI = 0.02–0.55; P = 0.008), while dizziness and ejaculation dysfunction rates were comparable.ConclusionMirabegron reduced pain episodes during treatment for distal ureteral stones, particularly when compared to silodosin, despite no significant differences in SER or SEI. …”
Get full text
Article -
7177
Takotsubo Syndrome in a Young Man
Published 2020-05-01“…Takotsubo syndrome is transient left ventricles dysfunction presenting as apical ballooning or midventricular enlargement with basal hyperkinesia of the left ventricle, while hemodynamically significant coronary artery stenosis is not found. …”
Get full text
Article -
7178
Impact of vitamin D supplementation on arterial vasomotion, stiffness and endothelial biomarkers in chronic kidney disease patients.
Published 2014-01-01“…<h4>Conclusion</h4>This study demonstrates for the first time improvement of endothelial vasomotor and secretory functions with vitamin D in CKD patients without significant adverse effects on arterial stiffness, serum calcium or FGF-23.…”
Get full text
Article -
7179
Acute Coronary Syndrome in Patients With 2 Type Diabetes Mellitus (Review of Literature; Description of the Clinical Case)
Published 2019-10-01“…The main mechanisms for the implementation of the effect of hyperglycemia include: activation of the polyolic pathway of glucose metabolism (sorbitol/aldose reductase); glycosylation of proteins; the effect of oxidative stress; increase of the role of diacylglycerols and activation of protein kinase isoforms as a result of enhanced formation of superoxide radical by inflammatory blood cells, smooth muscle cells, endothelial cells. …”
Get full text
Article -
7180
Cardiovascular events after polychemotherapy of oncohematological diseases: modern ways to prevention and treatment
Published 2013-06-01“…Heart dysfunction that occurred after using of cytostatic drugs and monoclonal antibodies may be a limit factor in treatment of oncohematological diseases. …”
Get full text
Article