Transcranial direct current stimulation combined with cognitive training improves two executive functions: Cognitive flexibility and information updating after traumatic brain inju... by Fatemeh Afsharian, Razieh Khorram Abadi, Reza Taheri, Saeid Abbasi Sarajehlou

“…Previous studies have examined the effects of non-invasive brain stimulation and cognitive training separately. …”
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Curcumin attenuates neuroinflammation and improves cognitive function in a rat model of febrile convulsions by Hamdiye Celikaslan, Davut Sinan Kaplan, Mustafa Orkmez

“…Abstract This study aimed to investigate the effects of curcumin on neuroinflammation and cognitive function in a rat model of febrile convulsions (FC). …”
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Mitochondrial DNA methylation is involved in contrast-induced renal tubular epithelial cell injury by Meiling Lv, Manyu Zhang, Sha Chen, Sheng Lu, Dingwei Yang

“…In conclusion, mtDNA methylation is involved in the mechanism of contrast-induced RTEC injury, potentially mediated by over-transcription of COX I and III, abnormal mtROS production, and subsequent mitochondrial damage and dysfunction. Inhibiting mtDNA methylation can provide protective effects against contrast - induced RTEC injury by reducing ROS (mtROS) production.…”
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Mechanistic Insights and Therapeutic Potential of Quercetin in Neuroprotection: A Comprehensive Review of Pathways and Clinical Perspectives by Ishita Debnath, Suman Ghosh, Sajal Kumar Jha, Sobhanjan Bhunia, Aditi Nayak, Souvik Basak, Sumit Nandi, Soumik Bhattacharjee

“…Quercetin demonstrated potent antioxidant effects by scavenging reactive oxygen species and modulating the Nrf2-ARE pathway, thereby mitigating oxidative stress, a hallmark of NDDs associated with mitochondrial dysfunction, protein aggregation, and neuronal apoptosis. …”
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Cardiovascular toxicity in testicular germ cell tumor survivors by Zuzana Orszaghova, Beata Mladosievicova, Michal Mego, Michal Chovanec

“…However, these survivors may experience acute and late adverse effects of cancer treatment, with cardiovascular toxicity being among the most serious and potentially life-threatening.MethodsThis narrative review synthesizes current evidence on cardiovascular toxicity in testicular cancer survivors, including clinical manifestations, pathophysiology of cisplatin-induced cardiovascular damage, additional adverse effects of radiotherapy, and prevalence of traditional cardiovascular risk factors. …”
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TRPV2 channels facilitate pulmonary endothelial barrier recovery after ROS-induced permeability by Lena Schaller, Martina Kiefmann, Thomas Gudermann, Alexander Dietrich

“…In this study, we investigated the roles of redox-sensitive transient receptor potential (TRP) ion channels, TRPM2, TRPV2 and TRPV4, in H2O2-induced endothelial barrier dysfunction. Using primary human pulmonary microvascular endothelial cells (HPMEC), we employed impedance-based resistance measurements, Western blot, and immunofluorescence staining to assess the effects of H2O2 on the endothelial barrier. …”
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The Soluble Platelet‐Derived Growth Factor β Receptor Induces Postoperative Delirium by Downregulating the Clearance of β‐Amyloid in the Brain by Zongfeng Guo, Chen Zhang, Xiang Wang, Weiguo Chen, Zongxiao Guo

“…CSF Aβ42 showed a significant mediating effect between CSF sPDGFRβ level and POD (22.45%). …”
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ANXA2 regulates mitochondrial function and cellular senescence of PDLCs via AKT/eNOS signaling pathway under high glucose conditions by Yanlin Huang, Zejing Qiu, Chunhui Jiang, Qian Fang, Jiaye Wang, Mingfang Han, Yizhao Liu, Zehui Li

“…After that, we used AKT and eNOS inhibitors to demonstrate the protective effect of ANXA2 on PDLCs under high glucose conditions. …”
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Efficacy and Safety of Visible and Near-Infrared Photobiomodulation Therapy on Astenospermic Human Sperm: Wavelength-Dependent Regulation of Nitric Oxide Levels and Mitochondrial E... by Matilde Balbi, Rachele Lai, Sara Stigliani, Claudia Massarotti, Matteo Bozzo, Paola Scaruffi, Silvia Ravera, Andrea Amaroli

“…Male infertility is a growing global concern, with asthenozoospermia being an important contributing factor. Mitochondrial dysfunction and changes in the metabolism of nitric oxide (NO) are key determinants of reduced sperm motility. …”
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Impact of COVID-19 on the endocrine system by D. N. Zadumina, V. V. Skvortsov, D. A. Shtonda

“…Today, it is important to study the effect of COVID-19 on the endocrine part of the pancreas, hypothalamic-pituitary-adrenal and hypothalamic-pituitary-thyroid axis. …”
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2, 2′, 4, 4′-tetrabromodiphenyl ether induces thyroid toxicity by targeting BRAF-mediated MEK-ERK-NIS pathway in human thyroid follicular epithelial cells by Guangshan Xie, Jinping Lu, Jiayi Song, Jianqing Zhang

“…These findings elucidated a novel mechanism of BDE-47-induced thyroid toxicity, highlighting BRAF as a critical mediator for PBDEs-related thyroid dysfunction, offering insights for targeted interventions.…”
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Long-term sequelae of coronavirus disease: long COVID-19 and cardiovascular outcomes (a literature review) by A. V. Hovornyan, T. O. Ilashchuk

“…The aim: to summarize the available data and modern views on the long-term cardiovascular effects of COVID-19, to reveal probable causes and risk factors for their development, as well as to analyze the presented information on the pathogenetic mechanisms of cardiovascular consequences after coronavirus disease. …”
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[Comment] Pelvic floor rehabilitation after rectal cancer surgery one-year follow-up of a multicenter randomized clinical trial (FORCE trial) by Huang Jian

“…[Objective] This study aims to evaluate the effects of pelvic floor rehabilitation (PFR) after low anterior resection (LAR) at one-year follow-up. …”
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Circulating programmed death-1 as a marker for sustained high hepatitis B viral load and risk of hepatocellular carcinoma. by Hsiang-Yun Cheng, Pei-Jen Kang, Ya-Hui Chuang, Ya-Hui Wang, Meng-Chin Jan, Chih-Feng Wu, Chih-Lin Lin, Chun-Jen Liu, Yun-Fan Liaw, Shi-Ming Lin, Pei-Jer Chen, Shou-Dong Lee, Ming-Whei Yu

“…<h4>Objective</h4>Recent evidence indicates a crucial role of the immunoinhibitory receptor programmed death-1 (PD-1) in enforcing T-cell dysfunction during chronic viral infection and cancer. …”
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Analgesic and Neuroprotective Roles of Dexmedetomidine in Spine Surgery: A Systematic Review by Spyridoula Roberta Afrati, Ioanna Lianou, Angelos Kaspiris, Vasileios Marougklianis, Anastasia Kotanidou, Spiros G. Pneumaticos

“…The effects of DEX were studied for up to 48 h postoperatively. …”
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Population Pharmacokinetic Modeling of the Oral Calcitonin Gene‐Related Peptide Receptor Antagonist Rimegepant in Adults by Craig M. Comisar, Jim H. Hughes, Jose Francis, Yorinao Chinda, Yamato Sano, Chieko Muto, Christine Neumar, Rajinder Bhardwaj, Richard Bertz, Jing Liu

“…A population pharmacokinetic analysis was performed to describe rimegepant's plasma concentration‐time course and to estimate covariate effects on rimegepant exposure. The model was developed/evaluated in 3 stages using data from 11 phase 1 clinical studies, wherein rimegepant was administered orally to healthy adults, elderly people with stable chronic illness(es), adults with renal or hepatic dysfunction, and healthy adults with Japanese or Chinese ethnicity. …”
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Red Rice Bran Ethanol Extract Reduces IL-1β as the Risk of Pancreas Fibrogenesis in Type 2 Diabetic Rat Model by Brian Wasita, Ratih Dewi Yudhani, Dyonisa Nasirochmi Pakha, Diana Nurrohima, Muthmainah Muthmainah, Nanang Wiyono, Shariza Fakurazi

“…BACKGROUND: Oxidative stress and inflammation contribute to pancreatic cell dysfunction that promote insulin resistance in type 2 diabetes (T2D). …”
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Complex Assessment of the Functional State of the Urinary System in Preclinical Studies. Part 1. Instrumental and Laboratory Assessment Methods (Review) by M. V. Miroshnikov, K. T. Sultanova, M. N. Makarova, N. M. Faustova, S. O. Khan, E. A. Loseva

“…The effects of a test substance on the urinary system should first be evaluated using minimally invasive methods. …”
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RETRACTED ARTICLE: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells by Ziyi Zhao, Yingwei Sun, Jing Tang, Yuting Yang, Xiaochao Xu

“…LRPPRC exerts its tumor-promoting effects mainly by regulating mitochondrial homeostasis and inducing oxidative stress. …”
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Tumor Initiation and Progression in People Living on Antiretroviral Therapies by Seun E. Olufemi, Daniel A. Adediran, Temitope Sobodu, Isaac O. Adejumo, Olumide F. Ajani, Elijah K. Oladipo

“…The interplay between HIV infection, chronic inflammation, immune restoration via ART, and the direct effects of ART drugs creates a unique cancer risk profile in PLWHA. …”
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