Motor dysfunction in elderly patients with chronic musculoskeletal system diseases (locomotive syndrome) by M. V. Putilina, N. V. Teplova, O. A. Gromova, I. Yu. Torshin, M. Yu. Maksimova, Yu. S. Prokofieva

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Impacts of mitochondrial dysfunction on axonal microtubule bundles as a potential mechanism of neurodegeneration by Scott Murray-Cors, Milli Owens, Yu-Ting Liew, Maureece Day, William Cairns, Andreas Prokop

“…Mitochondrial dysfunction is an important cause for neurodegeneration, often associated with dyshomeostasis of reactive oxygen species, i.e., oxidative stress. …”
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The impact of citicoline on brain mitochondrial dysfunction induced in rats after head irradiation by Nahed Abdel-Aziz, Fatma Rabia Algeda, Shereen M. Shedid

“…Abstract Head irradiation is a common treatment for brain cancer; however, it can cause side effects in healthy brain tissue. This study aimed to test whether citicoline administration modulates radiation-induced brain mitochondrial dysfunction in rats. …”
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Akkermansia muciniphila helps in the recovery of lipopolysaccharide-fed mice with mild intestinal dysfunction by Yue Hu, Yue Hu, Jun Zhou, Xiaoqi Lin

“…This study explores the therapeutic effects of Akkermansia muciniphila on LPS-induced mild intestinal dysfunction in mice.MethodsThirty-eight 6-week-old C57BL/6 mice were split into control (n = 19) and LPS-treated (n = 19) groups. …”
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COMPARISON OF ENALAPRIL AND PERINDOPRIL IN PATIENTS WITH ARTERIAL HYPERTENSION AND LEFT VENTRICLE SYSTOLIC DYSFUNCTION by Yu. I. Grinshtein, O. L. Barbarash, D. A. Yakhontov, A. E. Popelysheva, V. V. Shabalin, N. B. Osetrova

“…To compare efficacy of enalapril and perindopril in patients with arterial hypertension (HT) and left ventricle systolic dysfunction.Material and methods. Patients (n=51) with HT and left ventricle systolic dysfunction (ejection fraction<45%) were included in the prospective open randomized comparative study. …”
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Current state of myocardial revascularization in patients with severe left ventricular systolic dysfunction by S. V. Gautier, A. B. Mironkov, S. A. Sakhovsky

“…In most cases, severe left ventricular systolic dysfunction is a consequence of ischemic heart disease. …”
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Subcutaneous fat transplantation improves dermal adipose dysfunction by regulating autophagy and mitophagy by Zhijin Li, Junxian Wen, Nanze Yu, Xiaojun Wang

“…AFT upregulated these markers, suggesting a potential modulatory effect on autophagy and mitophagy. Conclusion: Dermal adipose dysfunction induced by PPAR-γ inhibition may involve dysregulation of autophagy and mitophagy. …”
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Endothelial dysfunction and its correction with perindopril therapy in patients with coronary heart disease by O. A. Vartanova, N. V. Mikhailova, T. E. Morozova

“…To investigate endothelial dysfunction (ED) in patients with coronary heart disease (CHD), stable effort angina, Functional Class (FC) I-III, as well as to study perindopril potential in ED correction.Material and methods. …”
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TREATMENT OF ERECTILE DYSFUNCTION IN PATIENTS WITH VIBRATION DISEASE CAUSED BY EXPOSURE OF LOCAL VIBRATION by E. V. Katamanova, S. S. Bichev

“…The diagnosis of erectile dysfunction was proved by clinical and instrumental data, besides we carried out survey with determination of international index of erectile dysfunction. …”
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Efficacy of Topical Azithromycin versus Systemic Doxycycline in Treatment of Meibomian Gland Dysfunction by Marwa Aly Zaky, Adel Galal Zaky, Moataz Fayez Elsawy, Kareem Fatehy Shehata, Mohamed Samy Abd Elaziz

“…Conclusions. Meibomian gland dysfunction (MGD) could be treated effectively with oral doxycycline and topical azithromycin by improving symptoms, clinical signs, and stabilization of tear film. …”
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Voluntary exercise alleviates ischemic brain injury in mice by modulating mitochondrial dysfunction by Beibei Li, Ye Zhou, Guifen Yang, Bo Li, Mingjin Zhu, Dan Lu, Senge Dai, Guoyuan Pan

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Changes in trace element composition of the brain under conditions of experimental myocardial dysfunction by А. G. Rodinskij, Ju. V. Kozlova

“…The results indicate ischemic-hypoxic effects in rat brain and can be used as markers of pathological processes.…”
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Decreased Extracellular Vesicle Vasorin in Severe Preeclampsia Plasma Mediates Endothelial Dysfunction by Saravanakumar Murugesan, Dylan R. Addis, Hanna Hussey, Mark F. Powell, Lakshmi Saravanakumar, Adam B. Sturdivant, Rachel G. Sinkey, Michelle D. Tubinis, Zachary R. Massey, Chelsi Patton, James A. Mobley, Alan N. Tita, Tamas Jilling, Dan E. Berkowitz

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Baicalein improves behavioral dysfunction induced by Alzheimer’s disease in rats by Zhou L, Tan S, Shan YL, Wang YG, Cai W, Huang XH, Liao XY, Li HY, Zhang L, Zhang BJ, Lu ZQ

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SFXN2 contributes mitochondrial dysfunction-induced apoptosis as a substrate of Parkin by Shishi Luo, Shishi Luo, Shishi Luo, Yechuan He, Yechuan He, Yaohui He, Yaohui He, Yaohui He, Danling Wang, Danling Wang, Danling Wang

“…Functional studies across multiple cell lines, including HEK293, SH-SY5Y, and N2a cells, reveal that the reduction of SFXN2 exacerbates mitochondrial damage-induced apoptosis, whereas overexpression of SFXN2 exhibits an anti apoptotic effect.DiscussionOur findings offer new insights into the regulation of SFXN2 in mitochondrial dysfunction through Parkin mediated ubiquitin proteasome system activity, underscoring SFXN2’s potential implications in nerodegenerative diseases, particularly PD.…”
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Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension by Meghamsh Kanuparthy, Rishik Manthana, Himanshu Kaushik, Kathy Xiang, Jad Hamze, David Marimekala, Jun Feng, Frank W. Sellke

“…Cardioplegic arrest and cardiopulmonary bypass (CP/CPB) are known to engender microvascular dysfunction in patients undergoing cardiac surgery. …”
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Clinical value of sublingual microcirculatory dysfunction for screening for primary aldosteronism in hypertensive patients by Wuhao Wang, Wei Liu, Yi Tang, Fang Sun, Hongbo He, Zhencheng Yan, Qiang Li, Zhiming Zhu, Zhiming Zhu

“…By plotting the receiver operating characteristic (ROC) curve, the CEI (AUC: 0.9818 [0.9660, 0.9977]) demonstrated a superior screening effect for PA compared with the aldosterone-to-renin ratio (ARR, AUC: 0.9505 [0.9194, 0.9817]).ConclusionsPatients with PA had marked microcirculatory dysfunction, which was strongly associated with the ARR. …”
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Intravascular Hemolysis of Red Blood Cells in the Development of Organ Dysfunctions in Critical Conditions by Yu. I. Orlov

“…Excess Fe2+ ions that have a high catalytic activity may exert a direct damaging effect on the capillary endothelium with the development of capillary leakage. …”
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Role of endothelial dysfunction in the pathogenesis of diabetic retinopathy in patients with type 2 diabetes by I. V. Vorobyeva, D. N. Gigineishvili

“…In the pathogenesis of DR is important to endothelial dysfunction and a variety of biochemical processes (an excess of intracellular sorbitol, non-enzymatic glycation of proteins, oxidative stress). there is a decrease in generation vasodilating factors, nitric oxide, with a simultaneous increase of endothelin, which causes vasoconstriction. …”
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The Relationship between Core Muscles Dysfunction and Chronic Ankle Instability: A Review by Navid Mohammadpour, Iman Rezaie, Mohammad Hadadi

“…Objective The aim of this study is investigate the core muscles dysfunctions and their consequences in patients with chronic ankle instability. …”
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