Pyrroloquinoline Quinone Improved Boar Sperm Quality via Maintaining Mitochondrial Function During Cryopreservation by Shanpeng Wang, Qi Wang, Lingjiang Min, Hailiang Cao, Adedeji O. Adetunji, Kaifeng Zhou, Zhendong Zhu

“…Due to oxidative damage and mitochondrial dysfunction, boar semen cryopreservation remains a significant challenge. …”
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Reduced Field-of-View Diffusion-Weighted Imaging of the Lumbosacral Enlargement: A Pilot In Vivo Study of the Healthy Spinal Cord at 3T. by Marios C Yiannakas, Francesco Grussu, Polymnia Louka, Ferran Prados, Rebecca S Samson, Marco Battiston, Daniel R Altmann, Sebastien Ourselin, David H Miller, Claudia A M Gandini Wheeler-Kingshott

“…However, DTI applications to the lower SC are limited due to a number of technical challenges, related mainly to the even smaller size of the SC structure at this level, its position relative to the receiver coil elements and the effects of motion during data acquisition. Developing methods to overcome these problems would offer new means to gain further insights into microstructural changes of neurological conditions involving the lower SC, and in turn could help explain symptoms such as bladder and sexual dysfunction. …”
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Early diagnosis of myocardial fibrosis in patients with epicardial obesity by O. V. Gritsenko, G. A. Chumakova, E. V. Trubina

“…Thus, the obtained data suggest that patients with EO have signs of preclinical LV diastolic dysfunction, which are characterized by an increase in LV untwisting rate and level of serum profibrotic factors.…”
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Bibliometric analysis of surface electromyography trends in stroke rehabilitation research by Zhiping Liao, Jianhua Li, Fangchao Wu, Yunxiang Xia, Yangzheng Li, Lina Ma, Lei Wu

“…Stroke, as a common clinical disease, has seen its mortality rate rising globally. Muscle dysfunction after stroke seriously affects the limb function of patients. …”
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FBXO38 Regulates Nox1 Stability to Reduce Vascular Endothelial Damage Induced by Low Oscillatory Shear Stress by Wan-li Yu, Li-wen Deng, Huan-huan Li, Chun-kai Wang, Xiang-yi Zuo, Zi-chang Wang, Li Meng, Lan-xin Wen, Wan-zhi Zeng, Yu Zhao, Xue-hu Wang

“…Oxidative stress and endothelial dysfunction are critical drivers of atherosclerosis, but the mechanisms regulating oxidative stress under disturbed flow conditions remain incompletely understood. …”
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Abnormal resting-state functional connectivity within the default mode network subregions in male patients with obstructive sleep apnea by Li H, Nie X, Gong H, Zhang W, Nie S, Peng D

“…Hai-Jun Li,1 Xiao Nie,1 Hong-Han Gong,1 Wei Zhang,2 Si Nie,1 De-Chang Peng11Department of Radiology, 2Department of Pneumology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, People’s Republic of ChinaBackground and objective: Abnormal resting-state functional connectivity (rs-FC) between the central executive network and the default mode network (DMN) in patients with obstructive sleep apnea (OSA) has been reported. However, the effect of OSA on rs-FC within the DMN subregions remains uncertain. …”
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In-Silico Investigation of <i>Phyllanthus niruri</i> Phytochemicals as Hepatic Fibrosis Modulators by Chithra Raju, Kavitha Sankaranarayanan

“…Acute factors like hepatitis and drug allergy and chronic causes like metabolic dysfunction-associated fatty liver disease (MASLD) and Hepatocellular carcinoma (HCC) drive hepatic wellness imbalances. …”
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Features of dissomnia and cognitive impairments in chronic cerebral ischemia due to diabetes mellitus type 2 by Yu. I. Kotsenko

“…Neuropsychological testing in combination with dyssomnia questionnaires and quantitative assessment of the severity of cognitive dysfunction is absolutely necessary.…”
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Elevated atherogenic index of plasma is associated with increased cardiorenal syndrome prevalence: a cross-sectional study by Sikai Xu, Jianping Hu, Zhiyi Ouyang, Maolin Yuan, Yan Zheng, Xin Liu, Yang Shen

“…Purpose Cardiorenal syndrome (CRS) is a complex clinical condition characterized by the simultaneous dysfunction of the heart and kidneys. The atherogenic index of plasma (AIP), calculated as the logarithm of the ratio of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C), has emerged as a potential biomarker for cardiovascular risk. …”
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Non-Bovine Milk as Functional Foods with Focus on Their Antioxidant and Anti-Inflammatory Bioactivities by Yan Li, Qingshan Ma, Mengmeng Li, Wenqiang Liu, Yihong Liu, Menghan Wang, Changfa Wang, Muhammad Zahoor Khan

“…Donkey milk exhibits particularly high lysozyme content and demonstrates significant immunomodulatory effects, while camel milk shows remarkable therapeutic potential in diabetes management, nephroprotection, and hepatoprotection. …”
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Mavacamten for Obstructive Hypertrophic Cardiomyopathy: Rationale for Clinically Guided Dose Titration to Optimize Individual Response by Anjali T. Owens, Milind Desai, Matthew T. Wheeler, Anna Rodonski, Samira Merali, Amy J. Sehnert, Sara Saberi

“…The dose‐titration strategy includes additional considerations for the potential onset of systolic dysfunction in the context of intercurrent illness, and for the potential of drug–drug interactions with inhibitors and substrates of cytochrome P450 enzymes. …”
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Olive oil Ameliorates renal Ischemia-reperfusion-mediated hepatic and renal changes in stressed rats by Noha S. Sobhy, Mona A. Ahmed, Noha N. Lasheen, Walaa Baher, Mohamed H. ElSayed

“…Chronic immobilization stress aggravated the effects of renal IR. Also, renal and hepatic morphological changes were more worsened. …”
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Assessment of Eustachian tube functioning following surgical intervention of Oral Submucus Fibrosis by using tympanometry &amp; audiometry by Sreea Roy, MDS, Abhay Taranath Kamath, MDS, Manish Bhagania, MDS, Adarsh Kudva, MDS, Kishan Madikeri Mohan, MSc Audiology,PhD

“…This feature is seldom/infrequently found in Group 2 and 3 and if encountered can be dealt effectively with surgical intervention.…”
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Self-referential cognition and empathy in autism. by Michael V Lombardo, Jennifer L Barnes, Sally J Wheelwright, Simon Baron-Cohen

“…Our results also highlight a specific dysfunction in ASC within cortical midlines structures of the brain such as the medial prefrontal cortex.…”
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Dimethyl fumarate attenuates liver injury in a mouse model of cecal ligation and puncture by modulating inflammatory, angiogenic and pyroptotic pathways by Heider Qassam, Ali M. Janabi, Karrar Kareem Gaen, Najah Rayish Hadi

“…Conclusion This study suggests that DMF has hepatoprotective effects on septic mice via the modulation of inflammation, adhesion molecules, angiopoietin 2 and pyroptosis.…”
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Anemia in diabetes mellitus: Pathogenetic aspects and the value of early erythropoietin therapy by Christina Antoniadou, Efstratios Gavriilidis, Konstantinos Ritis, Dimitrios Tsilingiris

“…Additional mechanisms comprise glomerular dysfunction, shortened erythrocyte lifespan, uremia-induced bone marrow suppression, and increased bleeding risk. …”
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Elucidation of Artemisinin as a Potent GSK3β Inhibitor for Neurodegenerative Disorders via Machine Learning-Driven QSAR and Virtual Screening of Natural Compounds by Hassan H. Alhassan, Malvi Surti, Mohd Adnan, Mitesh Patel

“…This study demonstrates the effectiveness of machine learning and computational screening in accelerating neurodegenerative drug discovery.…”
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circ-Katnal1 Enhances Inflammatory Pyroptosis in Sepsis-Induced Liver Injury through the miR-31-5p/GSDMD Axis by Kai Kang, Nana Li, Yang Gao, Changsong Wang, Pengfei Chen, Xianglin Meng, Wei Yang, Mingyan Zhao, Kaijiang Yu

“…Sepsis is a systemic inflammatory response that can elicit organ dysfunction as well as circulatory diseases in serious cases. …”
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Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Improve 5-FU-Induced Delayed Wound Healing by Mitochondrial Transfer by Hongbin Lai, Ling Lin, Yanrui Pan, Boqun Wang, Lan Ma, Wei Zhao

“…Rot pretreatment inhibited the therapeutic effects of UMSC-apoVs on wound healing by inducing mitochondrial dysfunction in UMSC-apoVs. …”
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Decreased seizure threshold in an eclampsia-like model induced in pregnant rats with lipopolysaccharide and pentylenetetrazol treatments. by Qian Huang, Lei Liu, Bihui Hu, Xiaodan Di, Shaun Patrick Brennecke, Huishu Liu

“…In separate experiments, MgSO4 (270 mg/kg IP) was injected in advance of PTZ into PE rats to observe its effect on PTZ-induced seizures.<h4>Results</h4>PE conditions were verified in rats after LPS administration by significantly higher blood pressure (P<0.01) and urinary albumin excretion (P<0.05), elevated sFlt-1 (P<0.05) and decreased PlGF serum levels (P<0.05), and evidence of hepatic dysfunction compared to control groups. …”
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