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  1. 621

    Stellate Ganglionectomy Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction by Hui Yan, Xiujun Li, Beilei Liu, Bin Wu, Changgui Chen, Liqun He, Gang Wu

    Published 2025-02-01
    “…This study examined the effects and mechanisms of stellate ganglionectomy on myocardial hypertrophy and cardiac dysfunction caused by pressure overload. …”
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  2. 622

    Diagnostic significance of TGF-β1 in kidney recipients with graft dysfunction by О. P. Shevchenko, S. О. Sharapchenko, D. A. Velikiy, О. Е. Gichkun, E. S. Stolyarevich, N. P. Mozheiko, D. A. Saydulaev, R. М. Kurabekova, E. A. Vakurova, A. A. Mamedova, M. A. Osoblivaya

    Published 2024-01-01
    “…Transforming growth factor beta 1 (TGF-β1), which has multiple effects in the body, among the potential indicators of complications.Objective: to assess the diagnostic significance of serum TGF-β1 in kidney recipients with graft dysfunction.Materials and methods. …”
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    Protective effects of Cordyceps militaris against hepatocyte apoptosis and liver fibrosis induced by high palmitic acid diet by Wan-Ting Tsai, Wan-Ting Tsai, Jiro Hasegawa Situmorang, Wei-Wen Kuo, Wei-Wen Kuo, Wei-Wen Kuo, Chia-Hua Kuo, Shinn-Zong Lin, Shinn-Zong Lin, Chih-Yang Huang, Chih-Yang Huang, Chih-Yang Huang, Chih-Yang Huang, Chih-Yang Huang, Tsung-Jung Ho, Tsung-Jung Ho, Tsung-Jung Ho, Tsung-Jung Ho

    Published 2025-01-01
    “…In vivo experiments involved FVB mice fed a NASH diet containing high levels of PA to induce FLD, with powdered CM administered orally to assess its impact on body weight, fasting blood glucose level, liver health, fibrosis, and markers of ER stress, inflammation, and oxidative stress.ResultsEAECM demonstrated protective effects against PA-induced apoptosis, mitochondrial dysfunction, ER stress, inflammation, and oxidative stress in vitro. …”
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  7. 627

    Effect of immune checkpoint inhibitor therapy on biventricular mechanics in cancer patients over a short-term follow-up: a systematic review by Andrea Sonaglioni, Antonino Bruno, Antonino Bruno, Gian Luigi Nicolosi, Emanuela Fossile, Cristian Rubuano, Riccardo Ricotta, Maria Gemelli, Michele Lombardo, Paola Muti, Paola Muti, Barbara Bassani

    Published 2025-06-01
    “…This systematic review has been primarily designed to summarize the main findings of these studies and to examine the overall effect of ICI therapy on biventricular mechanics in cancer patients.MethodsAll imaging studies evaluating the effect of ICI therapy on biventricular mechanics in cancer patients, selected from PubMed and EMBASE databases, were included. …”
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  8. 628

    The effect of empagliflozin on non-alcoholic fatty liver disease-related parameters in patients with type 2 diabetes mellitus: a randomized controlled trial by Fatemeh Shojaei, Azam Erfanifar, Saeid Kalbasi, Shahriar Nikpour, Latif Gachkar

    Published 2025-02-01
    “…Conclusion These findings suggest that Empagliflozin could be an effective adjunctive therapy for managing liver dysfunction in T2DM patients with NAFLD. …”
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  9. 629

    The effects of obesity on thyroid function in a metabolically healthy high-fat, high-carbohydrate diet-induced obese rat model by Reveshni Pather, Andile Khathi, Phikelelani Ngubane

    Published 2025-04-01
    “…IntroductionObesity is a recognized exacerbator of thyroid dysfunction due to its detrimental effects on energy homeostasis, appetite regulation, basal metabolic rate, thermogenesis, and metabolism. …”
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  10. 630

    Neuroprotective effects and mechanisms of the YiQiWenYangSanHan formula on Parkinson's disease mice by Jinling Liu, Dong Di, Suping Sun, Yan Sun, Shihan Zhou, Jing Liu, Zizhen Qin, Xinyu Yang, Xiao Wang, Zheng Xu, Boran Zhu, Haoxin Wu

    Published 2025-06-01
    “…Nevertheless, further research and validation are required to fully understand its protective effects and underlying mechanisms against PD. Aim of this review: This study employed an in vivo model to investigate the effects of YQWYSHF on motor impairments, neuroinflammation, and mitochondrial dysfunction in C57BL/6 J mice caused by MPTP. …”
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    Vasotoxic Effects of Anticancer Therapy: a Review of Current Data by Yu. A. Vasyuk, E. Y. Shupenina, A. G. Nosova, E. O. Novosel, D. A. Vyzhigin

    Published 2023-05-01
    “…The key mechanism for the development of vasotoxicity is endothelial dysfunction, and anticancer drugs can also affect the processes of thrombosis. …”
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  18. 638

    Synergies of dibutyl phthalate on high-fat diet can aggravate cardiac fibrosis/dysfunction and the protective effects of vitamin E and salidroside: A molecular toxicological study in Sprague-Dawley rats by Xiao Liang, Yang Wu, Qing Feng, Deyu Zhu, Qi Huang, Zhuangzhuang Wei, Ping Ma, Xu Yang, Cuiyu Bao, Xinyu Bao

    Published 2025-09-01
    “…However, it remains unclear whether DBP has a synergistic effect on HFD and whether the interaction between the two exacerbates cardiac fibrosis and dysfunction. …”
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  19. 639

    Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice by Wenqi Wang, Yidi Qu, Siyu Li, Jinyu Chu, Hongxin Yang, Lirong Teng, Di Wang

    Published 2023-07-01
    “…In this study, the neuroprotective effect of CCG through oxidative stress mediated mitochondrial dysfunction on L-glutamate (L-Glu)-damaged hippocampal neuron cell line (HT22) and APPswe/PSEN1dE9 transgenic (APP/PS1) mice were investigated. …”
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