Suggested Topics within your search.
Suggested Topics within your search.
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6301
Lumbar-peritoneal shunt for idiopathic normal pressure hydrocephalus and secondary normal pressure hydrocephalus
Published 2022-01-01“…Objectives: Normal-pressure hydrocephalus is a clinical syndrome consisting of dilated cerebral ventricles with the clinical triad of gait disturbance, cognitive impairment and/or urinary dysfunction. Lumbar-peritoneal (LP) shunt could improve idiopathic normal pressure hydrocephalus (iNPH) while its effectiveness on secondary NPH (sNPH) is elusive. …”
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6302
Inhibition of miR-128-3p Attenuated Doxorubicin-Triggered Acute Cardiac Injury in Mice by the Regulation of PPAR-γ
Published 2021-01-01“…The aim of this study was to investigate the biological effect of miR-128-3p in DOX-induced cardiotoxicity. …”
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6303
Knowledge mapping of exosomes in ischemic stroke: a bibliometric analysis
Published 2025-07-01“…Exosomes exhibit anti-inflammatory, immunomodulatory, anti-apoptotic, angiogenic, and neuroregenerative effects, as well as glial scar reduction and drug delivery effects in ischemic stroke. …”
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6304
Selective serotonin reuptake inhibitor use is associated with right ventricular structure and function: the MESA-right ventricle study.
Published 2012-01-01“…<h4>Conclusions</h4>SSRI use was associated with higher RVSV in cardiovascular disease-free individuals and, among men, greater RV mass and larger RVEDV. The effects of SSRI use in patients with (or at risk for) RV dysfunction and the role of sex in modifying this relationship warrant further study.…”
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6305
Evaluating the Potential of Portulaca oleracea L. for Parkinson’s Disease Treatment Using a Drosophila Model with dUCH-Knockdown
Published 2019-01-01“…Purslane has been reported to exert neuroprotective effects against several neurotoxins including rotenone and 6-OHDA in PD models. …”
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6306
Pregnancy in obese mice protects selectively against visceral adiposity and is associated with increased adipocyte estrogen signalling.
Published 2014-01-01“…We used a mouse model of high fat (HF) feeding to induce maternal obesity to identify adipose tissue-mediated mechanisms driving metabolic dysfunction in pregnant and non-pregnant obese mice. …”
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6307
Distinct roles for type I and type III interferons in virulent human metapneumovirus pathogenesis.
Published 2024-02-01“…Several virulent isolates caused severe weight loss, lung pathology, airway dysfunction, and fatal disease in mice, which was confirmed in three inbred mouse strains. …”
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6308
Performance of 119 Brazilian children on Stroop paradigm: Victoria version Desempenho de 119 crianças brasileiras no paradigma Stroop: versão Victoria
Published 2009-06-01“…BACKGROUND: The Stroop paradigm evaluates susceptibility to interference and is sensitive to dysfunction in frontal lobes. Performance in the Stroop changes along the development. …”
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6309
Homocysteine Mediates Cognitive Inflexibility Induced by Stress via Targeting PIN1
Published 2025-04-01“…Background: Increasing evidence shows that HCY plays an important role in stress-induced cognitive dysfunction, and HCY significantly promotes the decline of cognitive function. …”
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6310
Dynamics of neurocognitive indicators against the background of neuroprotective therapy of vertebrobasilar insufficiency with cerebral venous discirculation symptoms
Published 2022-03-01“…In addition, the inclusion of the drug in the therapy regimens for patients with this pathology showed a significant decrease in the frequency of complaints, including specific «venous» complaints, the severity of cephalgic syndrome, as well as asthenic and autonomic disorders, which had a positive effect on the patients’ quality of life. The results obtained make it possible to recommend the inclusion of the drug in the therapy regimens for patients with symptoms of cerebral venous dysfunction.…”
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6311
Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats
Published 2022-01-01“…We present the experimental finding that the preservation of vascular grafts with CM prevents endothelial dysfunction after IRI in diabetic rats. Targeting apoptosis by CM may contribute to its protective effect.…”
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6312
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice.
Published 2012-01-01“…Further, this disadvantageous vascular phenotype is exacerbated by age to influence the risk of developing obesity, raised blood pressure and endothelial dysfunction in adult life.…”
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6313
Gut Hormones and Inflammatory Bowel Disease
Published 2025-07-01“…These efforts may uncover safer, metabolically tailored treatments for IBD, particularly in patients with coexisting obesity or metabolic dysfunction.…”
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6314
Anti-remodeling efficacy of eprosartan in patients with essential hypertension, and gene polymorphism of angiotensin II type 1 receptors
Published 2005-02-01“…Aim. To study the effects of long-term eprosartan treatment efficacy on myocardial structure and function in patients with essential arterial hypertension (EAH), and the association of these effects with structural polymorphism of angiotensin II type 1 receptors (AT2RI). …”
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6315
Mirabegron nighttime versus daytime dosing for women with overactive bladder syndrome: a randomized controlled trial
Published 2025-08-01“…Abstract The effect of nighttime dosing versus daytime dosing of mirabegron is undetermined. …”
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6316
The essential oil from the rhizomes of Stahlianthus involucratus attenuates the progression of vascular aging and atherosclerosis by regulating Nrf2-mediated mitochondrial quality
Published 2025-05-01“…IntroductionAtherosclerosis (AS), characterized by chronic inflammation within the vasculature, is linked to endothelial dysfunction and oxidative stress. The senescence of vascular endothelial cells (VECs) serves as a pathological basis for AS. …”
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6317
Network Pharmacology and Transcriptomics Reveal the Mechanism of GuaLouQuMaiWan in Treatment of Type 2 Diabetes and Its Active Small Molecular Compound
Published 2022-01-01“…However, side effects and drug tolerance usually lead to treatment failure. …”
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6318
Ovotransferrin-depleted egg white hydrolysate reduces blood pressure in spontaneously hypertensive rats
Published 2024-01-01“…In the present study, we aimed to explore the antihypertensive effect of the ovotransferrin-depleted egg white hydrolysate prepared by thermoase (OD-EWH) in spontaneously hypertensive rats, using EWH as the reference. …”
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6319
Interplay of fatty acids, insulin and exercise in vascular health
Published 2025-01-01“…Elevated plasma levels of free fatty acids in people with insulin resistance engender vascular inflammation, endothelial dysfunction, and vascular insulin resistance. Importantly, these effects are both functionally and structurally dependent, with saturated fatty acids as the primary culprits, while polyunsaturated fatty acids may support insulin sensitivity and endothelial function. …”
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6320
The Role of <i>Substance P</i> in Corneal Homeostasis
Published 2025-05-01“…This review synthesizes current knowledge on SP’s involvement in corneal innervation, epithelial homeostasis, immune regulation, neovascularization, and wound healing, while highlighting its dichotomous effects in both promoting tissue repair and exacerbating inflammation. …”
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