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6241
Ultrasound guided pulsed radiofrequency neuromodulation of sphenopalatine ganglion treatment for allergic rhinitis in childern: A case report
Published 2024-09-01“…Pulsed radiofrequency (PRF) is a commonly used technique in pain management to produce neuromodulatory effects without damaging nerve tissue. Previous research suggests that SPG dysfunction is one of the important pathophysiological mechanisms of trigeminal autonomic cephalalgia, and PRF targeting SPG can effectively exert neuromodulatory effects to improve its symptoms. …”
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6242
Heavy metal(loid) bioaccumulation in fish and its implications for human health
Published 2024-12-01“…Here, we provided a general and concise conclusion from current research findings on the toxicological effects on different body systems. Exposure to HMs can lead to a range of adverse health effects, including neurological damage, developmental disorders, kidney damage, cardiovascular problems, and cancers. …”
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6243
Melatonin Enhances Tomato Salt Tolerance by Improving Water Use Efficiency, Photosynthesis, and Redox Homeostasis
Published 2025-07-01“…This study investigated the effects of varying MT concentrations on photosynthetic performance, plant water relations, water-use efficiency, and stress-responsive physiological parameters in tomatoes, aiming to identify the key physiological pathways for MT-mediated salt stress mitigation. …”
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6244
The chemotherapy agent doxorubicin induces CNS expression of Ascl1, a regulator of adult neurogenesis and differentiation
Published 2025-03-01“…Abstract Cancer-related cognitive impairment (CRCI) is a common side effect of cancer and its treatments. Cancer chemotherapy has been associated with hippocampal dysfunction and memory impairment. …”
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6245
Central Venoplasty in Patients with Cardiac Implantable Electronic Devices
Published 2021-01-01“…Two patients required early reinterventions within 10 days due to catheter dysfunction. Conclusion Findings of this study support the existing evidence on the safety and effectiveness of balloon angioplasty without lead extraction.…”
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6246
Sleep impact on obesity – literature review
Published 2025-05-01“…Poor sleep duration and quality, along with circadian misalignment, are linked to weight gain and metabolic dysfunction. While sleep-targeted interventions show potential for improving metabolic health and aiding weight loss, further research is needed to fully understand underlying mechanisms and lasting effects. …”
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6247
Identification of a metabolic brain network characterizing essential tremor
Published 2025-01-01“…Network expression showed inverse correlations with tremor severity and disease duration and positive correlations with cognitive dysfunction. DBS substantially alleviated tremor, but had only marginal effects on cognitive performance. …”
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6248
Emerging Psychotropic Drug for the Treatment of Trigeminal Pain: Salvinorin A
Published 2024-11-01“…However, their efficacy is often limited by common side effects, such as dizziness, vertigo, nausea, seizures, and cognitive symptoms. …”
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6249
Glucose homeostasis and cognitive functions in schizophrenia: a systematic review and meta-analysis
Published 2025-07-01“…Our findings suggest that glucose metabolism dysregulations might worsen cognitive dysfunctions in schizophrenia. However, further research is needed with larger samples and less heterogeneous studies to investigate if the effect is statistically significant. …”
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6250
Knockdown of hsa_circ_0001275 reverses dexamethasone-induced osteoblast growth inhibition via mediation of miR-377/CDKN1B axis.
Published 2021-01-01“…<h4>Background</h4>Osteoporosis affects the quality of life among middle-aged and elderly individuals. In addition, dysfunction of osteoblasts can lead to the progression of osteoporosis. …”
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6251
Echinacoside alleviates Ang II-induced cardiac fibrosis by enhancing the SIRT1/IL-11 pathway
Published 2025-01-01“…Objective(s): Echinacoside (ECH) is an anti-fibrotic phenylethanoid glycoside derived from the Cistanche plant that protects against cardiac dysfunction by mitigating apoptosis, oxidative stress, and fibrosis. …”
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6252
Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl-2 signaling pathway
Published 2024-12-01“…The expression of ANXA5 protein and mRNA was overexpressed, and knockdown of ANXA5 can effectively attenuate cardiomyocyte apoptosis and inflammatory response, ameliorate myocardial hypertrophy and cardiac dysfunction in ALD-induced hypertrophic cardiomyocytes and in SHR hypertrophic hearts. …”
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6253
Sappanone A mitigates cognitive impairment and oxidative stress through modulation of α7 nicotinic acetylcholine receptor in rats with trimethyltin-induced Alzheimer’s disease-like...
Published 2025-06-01“…Aim of the study: We evaluated the ameliorative effects of SAP on AD-like pathology induced in rats by the neurotoxicant trimethyltin (TMT). …”
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6254
Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferation
Published 2024-12-01“…In vitro studies demonstrated that ailanthone effectively inhibited PINK1-PRKN mediated mitophagy and promoted BAX-BAK1 mitochondrial pores formation through PRKN inhibition. …”
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6255
Role of sirtuins in epigenetic regulation and aging control
Published 2024-04-01“…Additionally, experimental data obtained in animal models, as well as data from population genomic studies, suggest a SIRT effect on life expectancy. At the same time, the diversity of sirtuin functions and biochemical substrates makes it extremely complicated to identify causeandeffect relationships and the direct role of SIRT in controlling the functional state of the body. …”
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6256
Amiodarone Induced Hyponatremia Masquerading as Syndrome of Inappropriate Antidiuretic Hormone Secretion by Anaplastic Carcinoma of Prostate
Published 2014-01-01“…Amiodarone is a broad spectrum antiarrhythmic agent widely used in the management of arrhythmias. The different side effects include thyroid dysfunction, visual disturbances, pulmonary infiltrates, ataxia, cardiac conduction abnormalities, drug interactions, corneal microdeposits, skin rashes, and gastrointestinal disturbances. …”
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6257
Ginseng-derived nanoparticles accelerate diabetic wound healing by modulating macrophage polarization and restoring endothelial cell function
Published 2025-10-01“…Vascular dysfunction and disruption of the balance between different subtypes of macrophages are key factors contributing to the poor healing of diabetic wounds. …”
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6258
An Interventional Brain-Computer Interface for Long-Term EEG Collection and Motion Classification of a Quadruped Mammal
Published 2025-01-01“…Brain-computer interfaces (BCI) acquire electroencephalogram (EEG) signals to effectively address postoperative motor dysfunction in stroke patients by discerning their motor intentions during significant movements. …”
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6259
Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria
Published 2025-08-01“…Abstract Mitochondrial dysfunction and accumulation of α-synuclein aggregates are hallmarks of the neurodegenerative Parkinson’s disease and may be interconnected. …”
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6260
Regulation of noradrenaline synthesis, uptake, and degradation in the left ventricle by fatty acid amide hydrolase (FAAH) inhibitor URB597 in the chronic unpredictable stress model...
Published 2024-01-01“…Depression has been linked to the dysfunction of the autonomic nervous system, which may cause dysregulation of the cardiovascular system. …”
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