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  1. 6241

    Ultrasound guided pulsed radiofrequency neuromodulation of sphenopalatine ganglion treatment for allergic rhinitis in childern: A case report by Zeyang Geng, Chenyang Wang, Ruilin Wang, Aimin Zhang

    Published 2024-09-01
    “…Pulsed radiofrequency (PRF) is a commonly used technique in pain management to produce neuromodulatory effects without damaging nerve tissue. Previous research suggests that SPG dysfunction is one of the important pathophysiological mechanisms of trigeminal autonomic cephalalgia, and PRF targeting SPG can effectively exert neuromodulatory effects to improve its symptoms. …”
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  2. 6242

    Heavy metal(loid) bioaccumulation in fish and its implications for human health by Dhary Alewy Almashhadany, Rzgar Farooq Rashid, Khalil Ibrahim Altaif, Sarhang Hayyas Mohammed, Hero Ismael Mohammed, Salah Mahdi Al-Bader

    Published 2024-12-01
    “…Here, we provided a general and concise conclusion from current research findings on the toxicological effects on different body systems. Exposure to HMs can lead to a range of adverse health effects, including neurological damage, developmental disorders, kidney damage, cardiovascular problems, and cancers. …”
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  3. 6243

    Melatonin Enhances Tomato Salt Tolerance by Improving Water Use Efficiency, Photosynthesis, and Redox Homeostasis by Chen Ru, Yuxuan Liu, Xingjiao Yu, Chuanliu Xie, Xiaotao Hu

    Published 2025-07-01
    “…This study investigated the effects of varying MT concentrations on photosynthetic performance, plant water relations, water-use efficiency, and stress-responsive physiological parameters in tomatoes, aiming to identify the key physiological pathways for MT-mediated salt stress mitigation. …”
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  4. 6244

    The chemotherapy agent doxorubicin induces CNS expression of Ascl1, a regulator of adult neurogenesis and differentiation by Christi Anne S. Ng, Morgan Pedus, Madeline F. Lee, Lawrence F. Kromer, Jeanne Mandelblatt, G. William Rebeck

    Published 2025-03-01
    “…Abstract Cancer-related cognitive impairment (CRCI) is a common side effect of cancer and its treatments. Cancer chemotherapy has been associated with hippocampal dysfunction and memory impairment. …”
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  5. 6245

    Central Venoplasty in Patients with Cardiac Implantable Electronic Devices by Mohammed Aljarie, Mohammed Alahmari, Mohammad Arabi

    Published 2021-01-01
    “…Two patients required early reinterventions within 10 days due to catheter dysfunction. Conclusion Findings of this study support the existing evidence on the safety and effectiveness of balloon angioplasty without lead extraction.…”
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  6. 6246

    Sleep impact on obesity – literature review by Kacper Buczek, Klaudia Kulig, Maksymilian Wiśniowski, Dominik Stanibuła, Patrycja Zwierzchlewska, Aneta Redner, Jakub Rybowski, Michal Popiel, Julia Głowacz, Kamil Dziekoński

    Published 2025-05-01
    “…Poor sleep duration and quality, along with circadian misalignment, are linked to weight gain and metabolic dysfunction. While sleep-targeted interventions show potential for improving metabolic health and aiding weight loss, further research is needed to fully understand underlying mechanisms and lasting effects. …”
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  7. 6247

    Identification of a metabolic brain network characterizing essential tremor by Solange Volnov, Hamzah Baagil, Oliver Winz, Hans-Juergen Kaiser, Sanne Katherina Meles, Joerg Bernhard Schulz, Kathrin Reetz, Felix Manuel Mottaghy, Florian Holtbernd

    Published 2025-01-01
    “…Network expression showed inverse correlations with tremor severity and disease duration and positive correlations with cognitive dysfunction. DBS substantially alleviated tremor, but had only marginal effects on cognitive performance. …”
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  8. 6248

    Emerging Psychotropic Drug for the Treatment of Trigeminal Pain: Salvinorin A by Geovanna Nallely Quiñonez-Bastidas, Lucia Elhy Grijalva-Contreras, Selene Isabel Patiño-Camacho, Andrés Navarrete

    Published 2024-11-01
    “…However, their efficacy is often limited by common side effects, such as dizziness, vertigo, nausea, seizures, and cognitive symptoms. …”
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  9. 6249

    Glucose homeostasis and cognitive functions in schizophrenia: a systematic review and meta-analysis by Alexander Kancsev, Eszter Éva Virág-Tulassay, Marie Anne Engh, Szilvia Kiss-Dala, András Attila Horváth, Péter Hegyi, Szabolcs Kéri

    Published 2025-07-01
    “…Our findings suggest that glucose metabolism dysregulations might worsen cognitive dysfunctions in schizophrenia. However, further research is needed with larger samples and less heterogeneous studies to investigate if the effect is statistically significant. …”
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  10. 6250

    Knockdown of hsa_circ_0001275 reverses dexamethasone-induced osteoblast growth inhibition via mediation of miR-377/CDKN1B axis. by Yan Xu, Liqin Sun, Juncheng Hu, Sai Xu

    Published 2021-01-01
    “…<h4>Background</h4>Osteoporosis affects the quality of life among middle-aged and elderly individuals. In addition, dysfunction of osteoblasts can lead to the progression of osteoporosis. …”
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  11. 6251

    Echinacoside alleviates Ang II-induced cardiac fibrosis by enhancing the SIRT1/IL-11 pathway by Yingbiao Wu, Zhongping Ning

    Published 2025-01-01
    “…Objective(s): Echinacoside (ECH) is an anti-fibrotic phenylethanoid glycoside derived from the Cistanche plant that protects against cardiac dysfunction by mitigating apoptosis, oxidative stress, and fibrosis. …”
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  12. 6252

    Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl-2 signaling pathway by Lina Zhao, Hongjuan Cao, Yao Yuan, Chunyan Liao, Dan Huang, Xiaoyi Li, Yueyao Zhao, Quanfeng Huang, Sha Li, Bei Zhang

    Published 2024-12-01
    “…The expression of ANXA5 protein and mRNA was overexpressed, and knockdown of ANXA5 can effectively attenuate cardiomyocyte apoptosis and inflammatory response, ameliorate myocardial hypertrophy and cardiac dysfunction in ALD-induced hypertrophic cardiomyocytes and in SHR hypertrophic hearts. …”
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  13. 6253

    Sappanone A mitigates cognitive impairment and oxidative stress through modulation of α7 nicotinic acetylcholine receptor in rats with trimethyltin-induced Alzheimer’s disease-like... by Kushagra Nagori, Madhulika Pradhan, Kartik T. Nakhate

    Published 2025-06-01
    “…Aim of the study: We evaluated the ameliorative effects of SAP on AD-like pathology induced in rats by the neurotoxicant trimethyltin (TMT). …”
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  14. 6254

    Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferation by Yan Qin, Ying Gao, Dan Wu, Qing-Qing Liu, Chang Su, Guan Liu, Le Yang, Ming-Gao Zhao, Jing-Yue Yao

    Published 2024-12-01
    “…In vitro studies demonstrated that ailanthone effectively inhibited PINK1-PRKN mediated mitophagy and promoted BAX-BAK1 mitochondrial pores formation through PRKN inhibition. …”
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  15. 6255

    Role of sirtuins in epigenetic regulation and aging control by E. M. Samoilova, S. E. Romanov, D.  A. Chudakova, P. P. Laktionov

    Published 2024-04-01
    “…Additionally, experimental data obtained in animal models, as well as data from population genomic studies, suggest a SIRT effect on life expectancy. At the same time, the diversity of sirtuin functions and biochemical substrates makes it extremely complicated to identify cause­and­effect relationships and the direct role of SIRT in controlling the functional state of the body. …”
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  16. 6256

    Amiodarone Induced Hyponatremia Masquerading as Syndrome of Inappropriate Antidiuretic Hormone Secretion by Anaplastic Carcinoma of Prostate by Pinaki Dutta, Girish Parthan, Anuradha Aggarwal, Santosh Kumar, Nandita Kakkar, Anil Bhansali, Fabio Rotondo, Kalman Kovacs

    Published 2014-01-01
    “…Amiodarone is a broad spectrum antiarrhythmic agent widely used in the management of arrhythmias. The different side effects include thyroid dysfunction, visual disturbances, pulmonary infiltrates, ataxia, cardiac conduction abnormalities, drug interactions, corneal microdeposits, skin rashes, and gastrointestinal disturbances. …”
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  17. 6257

    Ginseng-derived nanoparticles accelerate diabetic wound healing by modulating macrophage polarization and restoring endothelial cell function by Liangliang Fan, Xuxia Jia, Fusong Dong, Song Yang, Wenjing Li, Ronghua Zhao, Lijia Yin, Daqing Zhao, Jiawen Wang

    Published 2025-10-01
    “…Vascular dysfunction and disruption of the balance between different subtypes of macrophages are key factors contributing to the poor healing of diabetic wounds. …”
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  18. 6258

    An Interventional Brain-Computer Interface for Long-Term EEG Collection and Motion Classification of a Quadruped Mammal by Sining Li, Gan Liu, Fan Feng, Ziqing Chang, Wenyu Li, Feng Duan

    Published 2025-01-01
    “…Brain-computer interfaces (BCI) acquire electroencephalogram (EEG) signals to effectively address postoperative motor dysfunction in stroke patients by discerning their motor intentions during significant movements. …”
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  19. 6259

    Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria by Tetiana Serdiuk, Yanick Fleischmann, Dhiman Ghosh, Aro Delparente, Viviane Reber, Larissa Frey, David Rhyner, Juan Gerez, Norbert Volkmar, Lucie Kralickova, Guillaume Mas, Christian Dörig, Sebastian Hiller, Roger Schibli, Linjing Mu, Paola Picotti, Roland Riek

    Published 2025-08-01
    “…Abstract Mitochondrial dysfunction and accumulation of α-synuclein aggregates are hallmarks of the neurodegenerative Parkinson’s disease and may be interconnected. …”
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  20. 6260