A Review of the Relationship Between Insulin and Bone Health by Sivasree Ravindran, Sok Kuan Wong, Nur-Vaizura Mohamad, Kok-Yong Chin

“…In humans, inconsistent findings on the effects of circulating insulin levels and insulin resistance on bone health were mainly attributed to heterogeneity in age, gender, metabolic status, study designs, population characteristics, and assessment methods. …”
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Role of peroxisome proliferator-activated receptor alpha in neurodegenerative diseases and other neurological disorders: Clinical application prospects by Zijun Wu, Yuying Zhao, Shujing Hao, Mengyao An, Chengcheng Song, Jing Li

“…Both endogenous and exogenous peroxisome proliferator-activated receptor alpha agonists bind to the peroxisome proliferator-activated response element to exert their biological effects. Peroxisome proliferator-activated receptor alpha plays a significant therapeutic role in neurodegenerative diseases. …”
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Comparing Family Functioning and Maternal Anxiety in Children with Attention and Hyperactivity Disorder and Controls by Gonca OZYURT, Aynur AKAY PEKCANLAR, Yusuf OZTURK

“…The families of children with ADHD had more family dysfunction in roles, behavioral control, affective involvement subscales.. …”
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Continuous Theta-Burst Stimulation Promotes Paravascular CSF-Interstitial Fluid Exchange through Regulation of Aquaporin-4 Polarization in APP/PS1 Mice by Cheng Wu, Tuo Lin, Qian Ding, Ni Zhang, Zi-tong Ou, Gui-yuan Cai, Hong-ying Chen, Jia-yue Xu, Ge Li, Zhong Pei, Guang-qing Xu, Yue Lan

“…This study explored the regulatory effects of continuous theta-burst stimulation (CTBS) on the glymphatic system in APPswe/PS1dE9 (APP/PS1) mice with two-photon imaging. …”
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Compliance of medical practitioners with diabetic treatment guidelines in West Rand, Gauteng by Nneka J. Ohanson, Deidré Pretorius

“…The resultant effects were poor glycaemic control and thus numerous complications. …”
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P79 | AN INNOVATIVE FUNCTIONAL COOKIE MODULATES THE MUCOSA AND MYENTERIC PLEXUS IN THE GUT OF 3xTg-AD MOUSE MODEL OF ALZHEIMER’S DISEASE

“…It has been proposed that gut dysbiosis, dysfunction of the intestinal epithelial barrier, and vascular deposition of amyloid-beta (Aβ) in the gut may precede the cerebral deposition of Aβ in a transgenic mouse model of AD.1 A hypocaloric cookie with prebiotic-rich ingredients (red lentils) coated with a multi-strain probiotic (SLAB51®) enriched chocolate2 was tested on 3xTg-AD mice, a murine model of AD, to evaluate the protective effects on the mucosa and ENS of the ileum and colon. 8-week-old 3xTg-AD gender-balanced mice were divided into five groups and organized for the supplementation of functional cookies. …”
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Hypercoagulability and COVID-19 Infection by Alciona SASU, Cristina FIRU, Alexandra NADABAN, Adelina PALCU, Daniel PAPIU, Anca HERMENEAN, Coralia Adina COTORACI

“…More recent investigations have examined vaccine-related effects, particularly those associated with adenoviral vector-based vaccines such as ChAdOx1 and Ad26.COV2.S, where thromboembolic adverse events have been documented. …”
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Shoulder Pain: To Think Beyond the Myo-osseous Elements: A Case Report by MJ Abhinand, B Vijayanand, Karthikeyan

“…This positive postoperative outcome underscores the effectiveness of timely surgical intervention when conservative measures prove insufficient. …”
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Infant With In Utero Ketamine Exposure: Quantitative Measurement of Residual Dosage in Hair by Pen-Hua Su, Yan-Zin Chang, Jia-Yuh Chen

“…The drug ketamine is frequently abused for recreational use in Asia, but few studies in humans have focused on the effects of ketamine exposure during pregnancy on the health of neonates. …”
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Association of weight-adjusted waist index and Albuminuria in children and adolescents: A national population-based study. by Jiawen Huo, Jianfeng Liu, Jiying Chen, Qiaolin Li, Lanling Shen, Juanjuan Liang, Jie Jiang

“…While central obesity is known to contribute to renal dysfunction, the relevance of the weight-adjusted waist index (WWI), a novel indicator of central adiposity, has not been fully explored in children and adolescents.…”
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PATERNAL LYMPHOCYTE ALLOIMMUNIZATION IN THE TREATMENT OF INFERTILITY: A NEW LOOK AT AN OLD PROBLEM by N. A. Khonina, E. A. Ladigina, A. N. Vyatchinina, N. M. Pasman, E. R. Chernykh

“…Decreased production of blocking factors (BF) is a common manifestation of immune dysfunction in women with recurrent spontaneous abortions (RSA), and this disorder may be corrected by lymphocyte immunotherapy performed with paternal lymphocytes (LIT). …”
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Protective Role of AMPK against PINK1B9 Flies’ Neurodegeneration with Improved Mitochondrial Function by Guoliang Xiang, Xueyi Wen, Wenjing Wang, Tianchan Peng, Jiazhen Wang, Qinghua Li, Junfang Teng, Ying Cui

“…Adenosine 5′-monophosphate-activated protein kinase (AMPK)’s effect in PTEN-induced kinase 1 (PINK1) mutant Parkinson’s disease (PD) transgenic flies and the related mechanism is seldom studied. …”
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Restoration of miR-223-3p expression in aged mouse uteri with Samul-tang administration by Jihyun Kim, Sooseong You

“…Background: During the secretory phase of the estrous cycle, endometrium senescence is accompanied by biological mechanisms such as metabolic dysfunction and epigenetic changes, leading to decreased embryo receptivity and implantation failure. …”
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A mixture of ginger phenolic compounds enhances mitochondrial function, activates AMPK, and reduces lipid accumulation in adipocytes. by María Elizabeth Preciado-Ortiz, Berenice Pérez-Jiménez, Paulina Barrera-Gómez, Juan José Rivera-Valdés, Joshua Ayork Acevedo-Carabantes, Sarai Vásquez-Reyes, Armando R Tovar, Nimbe Torres, Ivan Torre-Villalvazo, Erika Martínez-López

“…Mitochondrial abundance and activity in adipocytes are critical for adequate adipose tissue function and whole-body energy homeostasis. Mitochondrial dysfunction in adipocytes impairs lipid metabolism, insulin sensitivity, and thermogenesis, leading to metabolic diseases. …”
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Anti-Müllerian hormone in PCOS: Molecular regulation and emerging therapeutic strategies by Yunmei Ke, Dan Tang, Qin Yang, Han Zhao, Jinyan Zheng, Caifen Zhu

“…Elevated AMH levels in PCOS impair follicle-stimulating hormone (FSH) sensitivity, disrupt follicular maturation, and contribute to androgen excess—creating a feedback loop that exacerbates ovarian dysfunction. This review explores the complex regulatory mechanisms governing AMH expression, including transcriptional, post-transcriptional, and post-translational processes. …”
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α-Terpineol Induces Shelterin Components TRF1 and TRF2 to Mitigate Senescence and Telomere Integrity Loss via A Telomerase-Independent Pathway by Marianna Kapetanou, Sophia Athanasopoulou, Andreas Goutas, Dimitra Makatsori, Varvara Trachana, Efstathios Gonos

“…Notably, we identify α-terpineol as an activator that effectively enhances TRF1 and TRF2 levels in a telomerase-independent manner, counteracting the senescence-associated decline in these crucial proteins. …”
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Carpolobia lutea methanol root extract reinstates androgenesis and testicular function in cadmiumchallenged rats by Ejike, Daniel Eze, Precious Nwaka, Okpa, Ugochukwu Vincent, Igbokwe, Moses, Dele Adams, Mohammed Rabiu, Karimah, Emmanuel Tiyo, Ayikobua

“…Cadmium produces a wide range of biological dysfunctions in human and laboratory animals where it chiefly affects the testes, whereas, Carpolobia lutea has been known to have antioxidant benefits. …”
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Carpolobia lutea methanol root extract reinstates androgenesis and testicular function in cadmiumchallenged rats by Ejike, Daniel Eze, Okpa Precious, Nwaka, Ugochukwu Vincent, Igbokwe, Moses, Dele Adams, Mohammed Rabiu, Karimah, Emmanuel Tiyo, Ayikobua

“…Cadmium produces a wide range of biological dysfunctions in human and laboratory animals where it chiefly affects the testes, whereas, Carpolobia lutea has been known to have antioxidant benefits. …”
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MiR‐146a engineered extracellular vesicles derived from mesenchymal stromal cells more potently attenuate ischaemia–reperfusion injury in lung transplantation by Xiucheng Yang, Shanchao Hong, Tao Yan, Mingzhao Liu, Mingyao Liu, Jin Zhao, Bingqing Yue, Di Wu, Jingbo Shao, Man Huang, Jingyu Chen

“…Abstract Background The limited donor lung pool for lung transplantation (LTx) is largely due to concerns over ischaemia–reperfusion injury (IRI), a major cause of primary graft dysfunction (PGD). NLRP3 inflammasome activation is known to play a pivotal role in the onset of IRI. …”
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Cognitive Behaviour Therapy untuk Mengurangi Prokrastinasi Akademik Siswa: Literature review by Rihya Syifa Qurrotu Ayuna, Eka Wahyuni

“…The results of the study revealed that CBT was very effective in reducing students' academic procrastination. …”
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