Efficacy assessment of antiretroviral drugs against equine infectious anemia virus in vitro by Cécile Schimmich, Astrid Vabret, José-Carlos Valle-Casuso

“…This study evaluates the in vitro antiviral effect of eighteen FDA-approved antiretroviral compounds from different drug families, in an equine cells in vitro infection model with EIAV reference strain. …”
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The Impact of Major and Minor Phytocannabinoids on the Maintenance and Function of INS-1 β-Cells Under High-Glucose and High-Lipid Conditions by Esmaeel Ghasemi Gojani, Bo Wang, Dong-Ping Li, Olga Kovalchuk, Igor Kovalchuk

“…Obesity-related increases in free fatty acids and glucose in the diet contribute to β-cell dysfunction and loss, ultimately leading to the onset of T2DM. …”
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Lipocalin 2 in Obesity and Diabetes: Insights into Its Role in Energy Metabolism by Erik Lindstrom, Jessica Deis, David A. Bernlohr, Xiaoli Chen

“…In metabolic diseases and mitochondrial metabolism, LCN2 appears to display paradoxical effects. While some studies link it to improved insulin sensitivity, glucose regulation, and mitochondrial function, others associate it with insulin resistance, obesity, and mitochondrial dysfunction. …”
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Neuronal ion channel modulation by Drimys winteri compounds: Opening a new chemical space to neuropharmacology by Macarena E. Meza, Oscar Ramirez-Molina, Oscar Flores, Katherine Fariña-Oliva, Pamela A. Godoy, Jorge Fuentealba, Gonzalo E. Yévenes

“…Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction, which depend on the function of ion channels. …”
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Chronic snus use in healthy males alters endothelial function and increases arterial stiffness. by Lukasz Antoniewicz, Mikael Kabele, Ulf Nilsson, Jamshid Pourazar, Gregory Rankin, Jenny A Bosson, Magnus Lundbäck

“…However, recent studies have demonstrated possible adverse cardiovascular effects in chronic snus users. The present study evaluates the effects of chronic snus use on vascular function by assessing central arterial stiffness and endothelial vasodilatory function in healthy chronic snus users as compared to matched non-users.…”
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Transnational economic development: Pakistani and Indian diaspora in focus by Kinza Tasleem Chauhdry

“…The aim of this study was to analyze the regulatory effect of Suaeda salsa extract (SSE) on T2DM and its effect on the intestinal flora of mice.ResultsThe results showed that SSE could significantly improve the body weight, fasting blood glucose (FBG), area under the curve (AUC) of the oral glucose tolerance test (OGTT), glycosylated serum protein (GSP) and islet function index. …”
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Personality Disorder and Changes in Affect Consciousness: A 3-Year Follow-Up Study of Patients with Avoidant and Borderline Personality Disorder. by Eivind Normann-Eide, Merete Selsbakk Johansen, Tone Normann-Eide, Jens Egeland, Theresa Wilberg

“…However, less is known about the more complex aims of improving the personality structure itself, such as identity- and interpersonal disturbances. Emotional dysfunction is closely associated with PD pathology. …”
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Passion fruit seed extract protects hydrogen peroxide-induced cell damage in human retinal pigment epithelium ARPE-19 cells by Haruka Uozumi, Shinpei Kawakami, Yuko Matsui, Sadao Mori, Akira Sato

“…These results indicated the cytoprotective effects of PFSE and piceatannol against oxidative stress in human ARPE-19 cells by resolving the dysfunction of mitochondrial and glycolytic energy metabolism.…”
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Operation Standard for Sling Exercise with Tuina Therapy of Traditional Chinese Medicine Rehabilitation Techniques by LI Li, CHANG Guangzhe, SUN Guodong, SUN Jinglong, FENG Ziyun, MA Zhaoshui, CHENG Yiran

“…It integrates traditional Chinese medicine massage and suspension exercise training to treat motor dysfunction with the help of sling training system based on the theory of meridians and collaterals in traditional Chinese medicine, modern biomechanical fascia theory and neurodevelopment theory. …”
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Dose-response relationships of physical activity with bone mineral density and muscle mass in visceral obesity: A metabolic heterogeneity perspective. by Hongxin Zhuo, Xintao Zhang

“…While physical activity (PA) benefits metabolic health, its dose-response effects on bone mineral density (BMD) and muscle mass in visceral obesity remain unclear.…”
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Identification of genetic markers associated with cisplatin-induced toxicity using public genomic databases by Suvam Banerjee

“…However, its clinical utility is often restricted by toxicities, such as nephrotoxicity, neurotoxicity and ototoxicity.1 Identifying genetic factors influencing these adverse effects is essential for developing personalised treatment strategies. …”
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Clinical outcomes of neuroendoscopic resection of brain abscess guided by electromagnetic navigation among patients presenting at Jieyang People's Hospital in China by Mindong Huang, Jiandan Zou

“…How to enhance the surgical effect and the positive rate of bacterial culture has always been our objective. …”
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A Case of Linezolid Toxicity Presenting as a Sepsis Mimic by Rashmi Mishra, Harish Patel, Bindu Goel, Trupti Vakde

“…Linezolid is an efficacious and well tolerated antimicrobial but can have serious adverse effects including myelo-suppression, serotonin syndrome, neuropathy, hypoglycemia, liver dysfunction, and lactic acidosis. …”
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Glycaemic variability in diabetes: a tool for assessing the quality of glycaemic control and the risk of complications by Vadim Valer'evich Klimontov, Natalya Evgen'evna Myakina

“…The mechanisms underlying the relationship between GV and vascular complications are being intensively studied, and recent data show that the effect of GV on vascular walls may be mediated by oxidative stress, chronic inflammation and endothelial dysfunction. …”
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Research the therapeutic, physicochemical, and pharmaceutical properties of the active compounds found in Tribulus terrestris (TT) by Roohallah Yousefi, Ali Jamshidi

“…Kaempferol, chrysin, and quercetin show inhibitory effects on specific cytochrome P450 enzymes. β-sitosterol and stigmasterol have high rates of skin absorption. …”
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Development of a Guava Jelly Drink with Potential Antioxidant, Anti-Inflammation, Neurotransmitter, and Gut Microbiota Benefits by Hai-Ha Nguyen, Jintanaporn Wattanathorn, Wipawee Thukham-Mee, Supaporn Muchimapura, Pongsatorn Paholpak

“…The Teng Mo, Fen Hong Mee, and Hong Chon Su guava varieties were screened for their polyphenol and flavonoid contents, antioxidant and anti-inflammatory effects, and suppressive effects on acetylcholinesterase (AChE), monoamine oxidase (MAO), GABA transaminase (GABA-T), and glutamate decarboxylase (GAD). …”
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Pyrimidinetrione benzodioxol ameliorates MAFLD-induced liver tumorigenesis and mood disorders in mice by Fang-Yu Hsu, Wan-Chun Chiu, Fat-Moon Suk, Chun-Ya Lee, Ming-Hua Hsu, Yi-Jen Liao

“…Abstract The Western diets (WD) induced metabolic dysfunction-associated fatty liver disease (MAFLD) has become a major clinical burden. …”
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Anodized Ti6Al4V-ELI, electroplated with copper is bactericidal against Staphylococcus aureus and enhances macrophage phagocytosis by Paula Milena Giraldo-Osorno, Adam Benedict Turner, Sebastião Mollet Barros, Robin Büscher, Simone Guttau, Farah Asa’ad, Margarita Trobos, Anders Palmquist

“…Abstract Implants aim to restore skeletal dysfunction associated with ageing and trauma, yet infection and ineffective immune responses can lead to failure. …”
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Dioraleze Drug-induced Kidney Injury In Rats by Asraa Abed Thiyab

“…Kidney examination revealed Dioraleze’s significant impact on the renal cortex and medulla in addition to its effect of other parts of kidney tissue. Thus, it was concluded that Dioraleze caused kidney abnormalities that may lead to kidney dysfunction in the body and may also have great impact on other visceral organs if not taken as per dose. …”
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Fipronil Triggers Immunotoxicity Through Reactive Oxygen Species-Driven Mitochondrial Apoptosis in Thymocytes by Jui-Fang Kuo, Yai-Ping Hsiao, Yao-De Wang, Hsin-Pei Weng, Chia-Chi Wang

“…Fipronil (FPN), a widely used pesticide, is associated with significant immunotoxic effects, particularly impacting thymocyte survival and immune homeostasis. …”
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