Acute high-fat high-sugar diet rapidly increases blood-brain barrier permeability in mice by Este Leidmaa, Andreas Zimmer, Valentin Stein, Anne-Kathrin Gellner

“…Long-term consumption of a high-fat high-sugar/Western diet (HFD) is known to induce BBB dysfunction. However, nothing is known about the immediate effects of acute HFD consumption on the BBB. …”
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Parkinson’s disease. Focus on early stages by E. A. Katunina, Z. A. Zalyalova, D. V. Pokhabov, M. Z. Ivanova, A. M. Semenova

“…A special place is given to piribedil, which, due to the dual mechanism of action, has a positive effect on cognitive functions, depression, apathy, as well as a minimal effect on daytime sleepiness.…”
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Advances in the relationship between AP-1 and tumorigenesis, development and therapy resistance by Xinni Xue, Zhiwei Li, Jiahui Zhao, Ziyi Zhao, Zhihang Li, Yong Li, Yawen Liu, Huan He

“…For tumor cells, AP-1 is considered to be a driver whose activity is associated with dysfunction and the onset, development, invasion, and migration of cancer. …”
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The Risk of Arrhythmias in Patients with COVID-19 by Lina Haj Ali, Loredana Suhov, Adrian Apostol, Larissa Dăniluc, Oana Sandu, Carina Bogdan, Viviana Mihaela Ivan

“…Additional mechanisms include the proarrhythmic effects of COVID-19 pharmacotherapies, drug–drug interactions, and associated autonomic dysfunction. …”
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ANTIHYPERTENSIVE THERAPY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: ADVANTAGES OF CALCIUM ANTAGONISTS by T. V. Adasheva, I. V. Fedorova, V. S. Zadionchenko, M. V. Macievich, V. V. Lee, S. V. Pavlov

“…Aim. To study effect of antihypertensive therapy with amlodipine maleat (Stamlo® M, “Dr. …”
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Optimizing Organ Donation After Euthanasia: A Critical Appraisal by E. A. J. Alkemade, H. D. Lam, B. J. C. Hendriks, A. E. Braat, I. P. J. Alwayn, M. J. Coenraad, A. G. Baranski

“…High doses of non-depolarizing neuromuscular blocking agents, particularly rocuronium, are associated with hepatotoxic effects in vitro. Furthermore, thiopental doses exceeding 750 mg significantly increase the risk of liver dysfunction. …”
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Validation and Discriminant Analysis of the Athens Insomnia Scale in Older Adults by Huseyin Elbi, Melike Batum, Ece Ozlem Oztürk, Merve Vatansever Balcan, Ayşin Kisabay Ak, Hikmet Yilmaz, Omer Aydemir

“…In the CFA, the goodness of fit indices of the two‐factor model was found to be significant, which supported the two‐dimension structure as a nocturnal sleep problem and its effects on daytime dysfunction. A high correlation was observed between the AIS and the PSQI. …”
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Quercetin alleviates acute pancreatitis by modulating glycolysis and mitochondrial function via PFKFB3 inhibition by Hai Jiang, Jia Liu, Zhipeng Xu, Qi Song, Junjie Tao, Heng Zhu, Qiliang Li, Lei Li

“…In vitro experiments using a cerulein-induced inflammatory pancreatic cell model assessed the effects of quercetin on PFKFB3 expression, glycolysis, and mitochondrial function. …”
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Delayed Facial Paralysis following Uneventful KTP Laser Stapedotomy: Two Case Reports and a Review of the Literature by P. Révész, Z. Piski, A. Burián, K. Harmat, I. Gerlinger

“…A dehiscent bony facial canal or a multiple microporotic fallopian canal (microtrauma or laser effect) can also contribute to the development of this rare phenomenon. …”
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A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population. by Jie Cheng, Miook Cho, Jin-ming Cen, Meng-yun Cai, Shun Xu, Ze-wei Ma, Xinguang Liu, Xi-li Yang, Can Chen, Yousin Suh, Xing-dong Xiong

“…SIRT1 exerts protective effects against endothelial cells dysfunction, inflammation and atherosclerosis, indicating an important role on myocardial infarction (MI) pathogenesis. …”
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Rho-Associated Kinase Inhibitor Fasudil Protects from Sepsis-Induced Acute Kidney Injury in Rat via Suppressing STAT-3 and NLRP-3 Pathway by Neslihan Şahin, Ejder Saylav Bora, Osman Sezer Çınaroğlu, Oytun Erbaş

“…Sepsis-associated acute kidney injury (S-AKI) is a severe complication in critically ill patients, marked by inflammation, oxidative stress, and renal dysfunction. This study aimed to evaluate the renoprotective effects of Fasudil (Fas), a Rho-associated kinase inhibitor, in a rat model of S-AKI induced by cecal ligation and puncture (CLP). …”
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Sympathetic Denervation Accelerates Wound Contraction but Inhibits Reepithelialization and Pericyte Proliferation in Diabetic Mice by Zhifang Zheng, Yu Wan, Yishu Liu, Yu Yang, Jianbing Tang, Wenhua Huang, Biao Cheng

“…Previous studies focused on the effects of sympathetic denervation with 6-hydroxydopamine (6-OHDA) on nondiabetic wounds, but the effects of 6-OHDA on diabetic wounds have not been previously reported. …”
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Role of balance exercise dynamic stress in rehabilitation of heart failure patients with reduced ejection fraction by Hanan Mohamed Ibrahim Elshoura, Ahmed Mohamed Ali Alashry, Salwa Galal Moussa

“…Additionally, skeletal muscle changes such as reduced mass, density, fiber type alterations, oxidative metabolism, and mitochondrial function contribute to muscle dysfunction in HF. These functional impairments increase the risk of falls, particularly in elderly individuals. …”
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Prolonged Inhalation Exposure to Coal Dust on Irradiated Rats and Consequences by Laura Chulenbayeva, Oralbek Ilderbayev, Dametken Suleymeneva, Aizhan Kaliyeva, Symbat Kabdykanov, Madiyar Nurgaziyev, Ayaulym Nurgozhina, Shynggys Sergazy, Samat Kozhakhmetov, Almagul Kushugulova

“…Particularly, the increase in radioactivity at the combined effect causes weakening of phagocytosis, and reduction in T lymphocytes by a factor of 2, immunoglobulin imbalance, and cytokine dysfunction develop secondary immune failure. …”
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Regeneration of the nerves in the aerial cavity with an artificial nerve conduit --reconstruction of chorda tympani nerve gaps-. by Toshiaki Yamanaka, Hiroshi Hosoi, Takayuki Murai, Takehiko Kobayashi, Yuji Inada, Tatsuo Nakamura

“…<h4>Objectives/hypothesis</h4>Due to its anatomical features, the chorda tympani nerve (CTN) is sometimes sacrificed during middle ear surgery, resulting in taste dysfunction. We examined the effect of placing an artificial nerve conduit, a polyglycolic acid (PGA)-collagen tube, across the gap in the section of the resected chorda tympani nerve (CTN) running through the tympanic cavity.…”
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Photobiomodulation therapy facilitates transplantation of dental pulp stem cells for spinal cord injury by Xinran Zhang, Wenwen Yang, Biao Zhu, Lin Su, Haotian Li

“…Background: While dental pulp stem cells (DPSCs) show therapeutic potential for spinal cord injury (SCI), post-traumatic oxidative stress and mitochondrial dysfunction critically compromise grafted cell survival. …”
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Barbigerone attenuates 3-nitropropionic acid-induced Huntington’s disease-like neuropathology in rats via antioxidant, anti-inflammatory, and neuroprotective mechanisms by Sattam Khulaif Alenezi

“…Histopathological examination revealed that barbigerone significantly restored the altered striatal architecture, indicating a protective effect against neurodegeneration. Barbigerone exhibits potential as a therapeutic choice for HD, offering the possibility of alleviating motor impairments, oxidative stress, inflammation, and cognitive dysfunction.…”
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MASLD: insights on the role of folate in hepatic lipid metabolism by Minlan Yang, Xiaoyu Xiao, Jie Mei, Pubu-ciren, Quan Gong

“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is also known as fatty liver disease associated with non-alcoholic fatty liver disease (NAFLD), which is a spectrum of chronic liver diseases characterized by steatosis, inflammation, fibrosis and liver injury. …”
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Randomized clinical study of electrical impedance tomography-guided chest physiotherapy in difficult-to-wean patients: study protocol by Hao Wang, Jianing Xi, Hongying Jiang

“…Background Diaphragm dysfunction and inadequate chest wall and respiratory muscle function are common in critically ill patients who face difficulties in weaning from mechanical ventilation (MV). …”
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Ameliorative Mechanism of Malvidin-3-O-glucoside on Chlorpyrifos-Induced PC12 Cell Injury by ZHU Rongchen, JING Shiji, LI Qi, FU Chengguo, HE Yang, WEN Liankui

“…This study aimed to investigate the protective effects and underlying mechanisms of malvidin-3-O-glucoside (Mv3G) on chlorpyrifos-induced damage of PC12 cells. …”
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