Explaining distortions in metacognition with an attractor network model of decision uncertainty. by Nadim A A Atiya, Quentin J M Huys, Raymond J Dolan, Stephen M Fleming

“…Distortions in metacognition are common in mental health disorders, though the neural underpinnings of such dysfunction are unknown. One reason for this is that models of key components of metacognition, such as decision confidence, are generally specified at an algorithmic or process level. …”
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Short-Term Relocation Stress-Induced Hematological and Immunological Changes in Saimiri boliviensis boliviensis by Pramod N. Nehete, Bharti P. Nehete, Akash G. Patel, Sriram Chitta, Henrieta Scholtzova, Lawrence E. Williams

“…The current study used squirrel monkeys as a model to investigate the stress-inducing effects of relocation within a facility, while animals acclimated to new situations (physical, housing). …”
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Novel spectrophotometric methods for concurrent assessment of duloxetine and avanafil in their binary mixture using derivative spectroscopy: greenness-blueness evaluation by Hadeer A. Elhamdy, Sayed M. Derayea, Khalid M. Badr El-Din, Mohamed Oraby

“…Abstract Antidepressant drugs, particularly selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are known to induce sexual dysfunction as a side effect. Duloxetine (DLX) and Avanafil (AVN) are simultaneously determined in their pure state and laboratory-prepared mixtures by two novel, environmentally friendly spectrophotometric methods. …”
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Study on the collaborative protective mechanism of Scutellariae Radix and Paeoniae Radix Alba against diabetic cardiomyopathy through the gut-heart axis by Cheng Fang, Xiaomin Xu, Fang Lu, Shumin Liu

“…Administering Scutellariae Radix and Paeoniae Radix Alba was shown to restore the equilibrium of the intestinal microbiota, modify metabolic pathways involving glycerophospholipids, arachidonic acid, and additional metabolites within the myocardial tissue through bile acid, taurine, and associated metabolic processes, resulting in lessened cardiac dysfunction, hypertrophy, and fibrosis in the diabetic cardiomyopathy mice. …”
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Connecting Molecular Characteristics of Intrauterine Growth-Retarded Piglets to Targeted Nutritional Interventions: A Review by Janghan Choi, Emma Traylor, Rachel Husak, Annabelle Foster, Aubrey Akere-Nkongho Tambe

“…These approaches consistently show that IUGR piglets exhibit systemic dysfunction, including compromised gut health, increased inflammation and oxidative stress, and impaired function of multiple organs such as the intestine, liver, kidney, and immune-related tissues. …”
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Architectural design for remote patient monitoring system implementation in hematology units: a proposed model by Rania Ahmed

“…The results of this study indicate the effectiveness of RPM in improving patient experience, and medication compliance, and reducing hospital readmissions. …”
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Alliin Induces Reconstitution of Testes Damaged by Estrogen Overstimulation by Regulating Apoptosis by Dae-Seung Kim, Min-Jee Oh, Sang-Hwan Kim

“…We analyzed the effect of alliin on the recovery of mouse testicular function and structure following estradiol treatment as well as on apoptosis regulation. …”
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The role of epicardial adipose tissue in the development of atrial fibrillation: a literature review by I. V. Tarasova, A. L. Vertkin

“…This article represents an overview of the most significant scientific works devoted to the problem of epicardial obesity and its relationship with atrial fibrillation, systematizes modern ideas about the potential proarrhythmogenic effect of epicardial adipose tissue, therapeutic possibilities and future prospects.…”
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The Role of Lactate in Immune Regulation: A Metabolic Rheostat via Transporters, Receptors, and Epigenetic Modifiers by Eun Jung Choi, Yoon Young Jang, Eun Joo Choi, Chang Joo Oh

“…Particular emphasis is placed on the dichotomous effects of endogenous versus exogenous lactate, with the former supporting glycolytic effector functions and the latter reprogramming immune cells toward regulatory phenotypes via redox shifts and epigenetic remodeling. …”
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Lactobacillus casei Shirota Supplementation Does Not Restore Gut Microbiota Composition and Gut Barrier in Metabolic Syndrome: A Randomized Pilot Study. by Vanessa Stadlbauer, Bettina Leber, Sandra Lemesch, Slave Trajanoski, Mina Bashir, Angela Horvath, Monika Tawdrous, Tatjana Stojakovic, Günter Fauler, Peter Fickert, Christoph Högenauer, Ingeborg Klymiuk, Philipp Stiegler, Manfred Lamprecht, Thomas R Pieber, Norbert J Tripolt, Harald Sourij

“…We aimed to investigate the effect of Lactobacillus casei Shirota (LcS) on gut microbiota composition, gut barrier integrity, intestinal inflammation and serum bile acid profile in metabolic syndrome. …”
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SMOKING AS AN UNFAVORABLE LIFESTYLE FACTOR FOR THE PROGRESSION OF PRIMARY OPEN-ANGLE GLAUCOMA by Clivia Erb, Alibek Amandykov, Carl Erb

“…Sidestream smoke, which constitutes 75% of total smoke, is more toxic than mainstream smoke and contributes to passive smoking.Smoking—both active and passive—causes mitochondrial dysfunction, oxidative stress, and systemic inflammation. …”
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Betahistine’s Neuroprotective Actions against Lipopolysaccharide-Induced Neurotoxicity: Insights from Experimental and Computational Studies by Vasudevan Mani, Minhajul Arfeen

“…Additionally, LPS led to increased neuroinflammation, oxidative stress, mitochondrial dysfunction, and apoptosis. Pre-treatment with BHTE effectively counteracted these effects, improving cognitive performance and restoring ACh levels. …”
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HMGA2 Promotes Brain Injury in Rats with Cerebral Infarction by Activating TLR4/NF-κB Signaling Pathway by Shaoyue Huang, Zhen Hong, Leguo Zhang, Jian Guo, Yanhua Li, Kuo Li

“…This study is aimed at evaluating the effects of HMGA2 on cerebral infarction-induced brain tissue damage and its underlying mechanisms. …”
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The Dual Role of Oxidative Stress in Atherosclerosis and Coronary Artery Disease: Pathological Mechanisms and Diagnostic Potential by Marcin Myszko, Jerzy Bychowski, Elżbieta Skrzydlewska, Wojciech Łuczaj

“…Oxidative stress plays a pivotal role in the pathogenesis of atherosclerosis and coronary artery disease (CAD), with both beneficial and detrimental effects on cardiovascular health. On one hand, the excessive production of reactive oxygen species (ROS) contributes to endothelial dysfunction, inflammation, and vascular remodeling, which are central to the development and progression of CAD. …”
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Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. by Oyinkan Sofola, Fiona Kerr, Iain Rogers, Richard Killick, Hrvoje Augustin, Carina Gandy, Marcus J Allen, John Hardy, Simon Lovestone, Linda Partridge

“…We have developed an adult-onset Drosophila model of AD, using an inducible gene expression system to express Arctic mutant Abeta42 specifically in adult neurons, to avoid developmental effects. Abeta42 accumulated with age in these flies and they displayed increased mortality together with progressive neuronal dysfunction, but in the apparent absence of neuronal loss. …”
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Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (K(Ca)2.3) in cerebral arteries. by Alister J McNeish, Francesc Jimenez-Altayo, Graeme S Cottrell, Christopher J Garland

“…<h4>Background</h4>In rat middle cerebral and mesenteric arteries the K(Ca)2.3 component of endothelium-dependent hyperpolarization (EDH) is lost following stimulation of thromboxane (TP) receptors, an effect that may contribute to the endothelial dysfunction associated with cardiovascular disease. …”
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Identifying the Superior Reperfusion Technique in Liver Transplantation: A Network Meta-Analysis by Yao Yao, Ping Wu, Tao Guo

“…To investigate the clinical effects of different reperfusion techniques in liver transplantation based on network meta-analysis. …”
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Pharmacogenetic and Clinical Predictors of Clopidogrel Insufficiency in a Patient with Atherosclerosis Obliterans of the Lower Extremities: Clinical Case by M. A. Andreyanova, K. B. Mirzaev, D. A. Sychev, K. A. Ryzhikova, A. V. Pokrovsky, A. F. Kharazov

“…A potential contribution of hepatic dysfunction to reduction in antiaggregant effect of P2Y12 inhibitor was demonstrated. …”
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NTN-1 attenuates amyloid-β-mediated microglial neuroinflammation and memory impairment via the NF-κB pathway and NLRP3 inflammasome in a rat model of Alzheimer's disease by Tianhang Wang, Yanchen Liu, Yidan Lu, Lijun Chi

“…Accordingly, this study aimed to investigate the effects of NTN-1 on cognitive impairment and to explore the anti-inflammatory properties related to the NLRP3 inflammasome and NF-κB signaling in Aβ1-42-induced rat models.MethodsWe assessed the effects of NTN-1 on neurobehavioral function, microglial activation and neuroinflammation mechanisms in Aβ1-42-treated rats using the Morris water maze test and Western blotting.ResultsOur results indicated that microinjections of NTN-1 attenuated Aβ1-42-induced memory and cognitive dysfunction and significantly inhibited microglial proliferation and NLRP3 inflammasome activation in the hippocampus and cortex of AD rats. …”
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Beyond the Scale: Investigating Adiponectin, ICAM-1, and VCAM-1 as Metabolic Markers in Obese Adolescents with Metabolic Syndrome by Nur Aisiyah Widjaja, Leonardo Alexander Caesar, Suhasta Nova, Eva Ardianah

“…Adiponectin acts to prevent vascular dysfunction due to obesity by inhibiting ICAM-1 and VCAM-1 expressions. …”
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