Deranged liver among Sudanese Patients with Dengue Virus Infection in Port Sudan Teaching Hospital by Bashir Abdrhman Bashir Mohamed

“…Objective This study aimed to evaluate the hepatic effect of dengue fever amongst Sudanese patients. …”
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Drought Tolerance in Plants: Physiological and Molecular Responses by Mostafa Haghpanah, Seyyedhamidreza Hashemipetroudi, Ahmad Arzani, Fabrizio Araniti

“…Osmotic stress, dehydration stress, dysfunction of plasma and endosome membranes, loss of cellular turgidity, inhibition of metabolite synthesis, cellular energy depletion, impaired chloroplast function, and oxidative stress are among the most critical consequences of drought on plant cells. …”
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High glucose affects the cardiac function of diabetic Akita mice by inhibiting cardiac ATP synthase beta subunit by Yuanfang Ma, Guang Wang, Jing Li

“…Furthermore, study on primary culture of cardiomyocytes hints that the effect of high glucose on myocardium and ATP are related to the decrease of the expression of ATP synthase β subunit. …”
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Thermographic Insights into Degenerative Spinal Disorders: Evaluating the Diagnostic Potential of Digital Infrared Thermography Imaging by Sathish Muthu, Guna Pratheep Kalanchiam, Ashok Shyam

“…While DITI offers advantages such as real-time functional assessment, cost-effectiveness, and early disease detection, challenges related to standardization, environmental variability, and specificity persist. …”
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CLINICAL AND INSTRUMENTAL ASSESSMENT OF MORPHO-FUNCTIONAL CONDITION OF THE HEART AND VASCULATURE IN COMORBIDITY OF ARTERIAL HYPERTENSION AND DIABETES MELLITUS TYPE 2 by N. Z. Babayeva

“…Significant differences between the AH and AH+DM-2 subgroups were discovered, which confirmed the significant effect of DM-2 on various parameters of the cardiovascular system. …”
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Uric Acid in Primary Hyperparathyroidism: Marker, Consequence, or Bystander? by Matteo Malagrinò, Guido Zavatta

“…Key mechanisms seem to involve tubular and intestinal transporters, particularly the ABCG2 transporter, as well as indirect effects mediated by hypercalcemia and inflammatory processes. …”
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Modulating Ferroptosis in Aging: The Therapeutic Potential of Natural Products by Sherif Hamidu, Seth Kwabena Amponsah, Abigail Aning, Latif Adams, Justice Kumi, Eunice Ampem-Danso, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Gabriel Tettey Ador, Sanjida Khatun

“…Natural products such as resveratrol, curcumin, and epigallocatechin gallate (EGCG) exhibit promising anti-ferroptotic effects through mechanisms including iron chelation, ROS scavenging, and upregulation of endogenous antioxidants. …”
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Polymorphism of protein genes associated with endothelial function in patients with infective endocarditis by A. V. Ponasenko, A. V. Tsepokina, A. G. Kutixin, Yu. A. Kudryavtseva

“…The study confirms the presence of endothelial dysfunction markers in the blood of patients with IE. …”
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Chlorpromazine-tadalafil interaction leading to refractory ischemic priapism and penile prosthesis implantation: a case report by Can Arici, Mert Basaranoglu, Selahittin Cayan, Murat Bozlu, Erdem Akbay

“…The synergistic pharmacological effects of alpha-adrenergic blockade and phosphodiesterase type 5 inhibition created a severe clinical presentation necessitating immediate penile prosthesis implantation. …”
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Construction of a risk and prognostic model for migrasome-associated lncRNAs in renal cell carcinoma by Liangwei Zhao, Fengjiao Geng, Xiaomin Ji, Chaoqun Geng, Tian Liu

“…In addition, to identify potential immunotherapeutic agents, we analyzed tumor immune dysfunction and exclusion scores; we also conducted immune cell infiltration profiling. …”
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The role of IP3 receptors and SERCA pumps in restoring working memory under amyloid β induced Alzheimer's disease: a modeling study by Ziyi Huang, Lei Wang

“…In this study, we investigate the effects of intracellular calcium homeostasis on AD-related working memory (WM) using a spiking network model. …”
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Mesenchymal Stromal Cell-Derived Extracellular Vesicles in the Management of Atopic Dermatitis: A Scoping Review of Therapeutic Opportunities and Challenges by Al-Masawa ME, Elfawy LA, Ng CY, Ng MH, Law JX

“…We thoroughly reviewed both human and animal studies, analyzing aspects such as the source, isolation, and characterization of MSC-EVs, as well as the animal and disease models, dosage strategies, efficacy, mechanisms, and adverse effects. While this review highlights the promising potential of MSC-EV therapy for AD, it also emphasizes significant challenges, including heterogeneity and insufficient reporting. …”
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The Mechanisms of Cadmium Toxicity in Living Organisms by Slavena Davidova, Viktor Milushev, Galina Satchanska

“…Cd was a proven carcinogen, and exposure to this metal has been linked to various adverse health effects, which were first reported in the mid-19th century and thoroughly investigated by the 20th century. …”
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Management of hepatocellular carcinoma in elderly and adolescent/young adult populations by Han Ah Lee

“…Elderly patients with HCC typically present with hepatitis C virus infection, metabolic dysfunction-associated steatotic liver disease, well-differentiated tumors, and multiple comorbidities. …”
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Smooth muscle cell-specific deletion of TXNIP ameliorates medial vascular calcification by Ae-Rang Hwang, Chang-Hoon Woo

“…By contrast, targeted genetic modifications to induce TXNIP deficiency in smooth muscle cells significantly mitigate these effects. Moreover, suppression of TXNIP in these models inhibited inflammasome activation, upregulation of mitotic regulators and mitochondrial dysfunction, suggesting a novel linkage between TXNIP activity and osteogenic differentiation pathways in medial calcification. …”
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Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes by Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev

“…Mechanically activated (MA) Piezo1 channels play an important role in both normal physiology and pathological dysfunction in multiple tissues and organs. In skeletal muscle cells, Piezo1 channels are involved in the regulation of postnatal myogenesis and muscle regeneration after injury. …”
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Neuropsychiatric Manifestations of Lyme Disease: A Literature Review of Psychiatric and Cognitive Impacts by Gabija Šegždaitė, Odeta Aliukonytė, Kamilė Pociūtė

“…For neurological symptoms, the analysis focused on studies addressing cognitive dysfunction.Results: Acute neuroborreliosis may have minimal effects on the cognitive function and typically resolves well with treatment. …”
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Chronic Administration of Tadalafil Improves the Symptoms of Patients with Amicrobic MAGI: An Open Study by Sandro La Vignera, Rosita A. Condorelli, Laura M. Mongioi, Aldo E. Calogero

“…Aim of this study was to evaluate the effects of pharmacological treatment with Tadalafil 5 mg daily on symptoms and quality of sperm parameters in selected patients with amicrobic MAGI (male accessory gland inflammation). 120 patients with amicrobic MAGI (mean age 27.0 ± 6.0 years) with mild-moderate ED (erectile dysfunction) according to IIEF-5 (International Index of Erectile Function 5 Items) scores underwent pharmacological treatment with Tadalafil 5 mg daily for six months. …”
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Pathophysiological and clinical significance of mineral homeostasis disorders in the development of cardiovascular disease by A. G. Kutikhin

“…Here, we critically discuss the pathophysiological consequences of CPP formation, mechanisms of their pathogenic effects, and potential therapeutic interventions.…”
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Cardiotoxicity in Children With Acute Ieukemia Treated by Anthracycline; Detected by Cardiac Troponins and Echcocardiography by Yaran Abbas Abdulqader, Mouroge Hashim Al-Ani, Nadine Abdulrazzak Mahmood

“… Background and objectives:the use of anthracycline antineoplastic agents has conducted to improved pediatric malignancies’ outcomes, yet their use is limited by their potential cardiotoxic effects. Thus, children who have received anthracyclines require cardiac evaluation periodically. …”
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