Suggested Topics within your search.
Suggested Topics within your search.
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5821
Deciphering Heat Stress Mechanisms and Developing Mitigation Strategies in Dairy Cattle: A Multi-Omics Perspective
Published 2025-07-01“…Heat stress (HS) in dairy cattle triggers systemic physiological disruptions, including milk yield decline, immune suppression, and reproductive dysfunction, jeopardizing sustainable livestock production. …”
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5822
Senescence-like Phenotype After Chronic Exposure to Isoproterenol in Primary Quiescent Immune Cells
Published 2024-11-01“…Chronic stress is associated with a higher risk for carcinogenesis as well as age-related diseases and immune dysfunction. There is evidence showing that psychological stress can contribute to premature immunosenescence. …”
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5823
GLP-1 receptor agonists and pulmonary hypertension in diabetes: A promising therapeutic strategy
Published 2025-07-01“…Methods: We synthesized data from preclinical and clinical studies, including large-scale observational cohorts, investigating GLP-1RAs' effects on pulmonary vasculature and hemodynamics. …”
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5824
Pituitary Insufficiency and Hyperprolactinemia Associated with Giant Intra- and Suprasellar Carotid Artery Aneurysm
Published 2015-01-01“…Endovascular treatment was performed on the patient to decrease the mass effect of aneurysm and improve the hypophysis dysfunction. …”
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5825
Alterations in Olfactory Cortex Volume in Mild Cognitive Impairment and Mild Alzheimer’s Disease Dementia: A Study of Sex-Related Differences
Published 2025-06-01“…Conclusions: This finding indicates greater pathological effects in this region in females at an earlier disease stage than in males. …”
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5826
Relationship between Uric Acid with Thyroid Disorders of Diabetic Patients in Iraq
Published 2024-12-01“…The study showed the effect of uric acid through the correlation coefficient for both clinical and hormonal indicators in diabetic patients with thyroid dysfunction. …”
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5827
GENOMIC FACTORS (TOLL-LIKE RECEPTORS GENES) IN DEVELOPMENT OF ATHEROSCLEROSIS AND ITS CLINICAL MANIFESTATIONS
Published 2017-07-01“…They exert different effects upon vascular wall and participate in development of universal inflammatory response. …”
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5828
The role of acupuncture in treating premature ejaculation and its probable neurobiological mechanism
Published 2024-12-01“…Abstract Background Premature ejaculation (PE) is one of the most common diseases in andrology and leads to serious male sexual dysfunction. Although several targeted oral drug therapies are used to treat PE, they often face challenges related to imprecise targeting and adverse effects. …”
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5829
Survivin Interference and SurVaxM as an Adjunct Therapy for Glioblastoma Multiforme
Published 2025-05-01“…Although phase I and II clinical trials suggest relatively safe adverse effects and potential efficacy, additional research is necessary to evaluate further how this vaccine may compare to standard treatment.…”
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5830
CHEMERIN AS A POTENTIAL REGULATOR OF MITOCHONDRIAL QUALITY CONTROL IN OBESE PATIENTS
Published 2021-10-01“…It has been proven that a change (decrease) in the number of mtDNA copies in insulin-dependent tissues can have a protective effect on mitochondria under conditions of increased oxidative stress. …”
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5831
Prosopagnosia as a Type of Conversion Disorder
Published 2018-01-01“…Neuropsychological testing indicated right temporal lobe dysfunction. Extensive work-up outruled an organic aetiology. …”
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5832
Trigger factors of general body overheating (scientific review)
Published 2024-12-01“…Exogenous hyperthermia contributing and predisposing factors are identified, timely detection and prevention of which will allow medical and social workers to limit the detrimental effects of hot conditions on public health.…”
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5833
Immunostimulating and Anticancer Activities of the Pectic Polysaccharide from <i>Panax ginseng</i> Leaves Treated with High Pressure/Enzyme Process
Published 2025-04-01“…Furthermore, GLHP showed significant anticancer effects, even in mice with NK cell dysfunction, via the anti-asialo GM1 antibody. …”
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5834
Ginseng for health care: a systematic review of randomized controlled trials in Korean literature.
Published 2013-01-01“…Six RCTs tested ginseng compared with placebo for erectile dysfunction, while another four studies evaluated the effects of ginseng against no treatment for gastric and colon cancer. …”
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5835
Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C
Published 2025-01-01“…Abstract Pro-inflammatory cytokines, like interleukin-1 beta and interferon gamma, are known to activate signalling pathways causing pancreatic beta cell death and dysfunction, contributing to the onset of diabetes. …”
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5836
Spinal cord injury: pathophysiology, possible treatments and the role of the gut microbiota
Published 2024-12-01“…Spinal cord injury (SCI) is a devastating pathological state causing motor, sensory, and autonomic dysfunction. To date, SCI remains without viable treatment for its patients. …”
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5837
The Relationship Between Interleukin-1β Levels and Visual Analog Scale Value in Preeclampsia Patients Who Received Perioperative C-Sectional Parecoxib With Spinal Anesthesia
Published 2024-07-01“…Background: Interleukin1β (IL-1β) increases during inflammation and functions as a mediator that terminates endothelial dysfunction and regulates cellular apoptosis in preeclampsia. …”
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5838
Current insights in noise-induced hearing loss: a literature review of the underlying mechanism, pathophysiology, asymmetry, and management options
Published 2017-05-01“…Furthermore, it is recently shown that acoustic trauma is associated with vestibular dysfunction, with associated dizziness that is not always measurable with current techniques. …”
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5839
Mitochondria-associated endoplasmic reticulum membranes and myocardial ischemia: from molecular mechanisms to therapeutic strategies
Published 2025-03-01“…Particular focus was directed at the far-reaching effects of MAMs in regulating key pathological events including calcium homeostasis, mitochondrial dysfunction, ER stress, oxidative stress, and autophagy in ischemic heart disease (IHD). …”
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5840
Development and Validation of Tadalafil Determination in Human Plasma by HPLC-MS Method
Published 2019-05-01“…Tadalafil is a drug used to treat erectile dysfunction. For the quantitative determination of tadalafil in human plasma are used methods of high performance liquid chromatography with ultraviolet and tandem mass spectrometric detection, during the analytical part of pharmacokinetic studies. …”
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