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5701
Characteristics of Intestinal Microbiota and Host Gene Regulation in <i>Coilia nasus</i> Responding to Stress
Published 2025-05-01“…This study investigated the effects of transport stress on intestinal microbiota, host gene regulation, and metabolic responses in <i>Coilia nasus</i>. …”
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5702
Some Aspects of Vascular Theory of Development and Progression of Primary Open-Angle Glaucoma (Literature Review). Part 1
Published 2019-03-01“…Violations of the universal mechanism of vascular tone regulation, namely endothelial dysfunction are described. Vascular endothelium is a barrier between vascular wall and blood plasma. …”
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5703
Role of Vitamin D in Systemic Sclerosis: A Systematic Literature Review
Published 2021-01-01“…Vitamin D is a steroid hormone with pleiotropic effects beyond its traditional role in calcium and bone homeostasis. …”
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5704
Research progress on the role of exercise-regulated reactive astrocytes in the prevention and treatment of Parkinson’s disease
Published 2025-06-01“…Nonetheless, in the context of Parkinson’s disease (PD), astrocytes may become dysfunctional, contributing to neurotoxicity, which is intricately linked to the etiological factors of PD. …”
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5705
The role of probiotics in combination therapy of depressive disorders
Published 2021-03-01“…Our objective was to investigate the effect of probiotic therapy on the profile of a psycho-emotional state and nature of neuro-immune-endocrine changes among patients with depressive disorders. …”
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5706
Increased resting heart rate indicates high-workload hearts with augmented aortic hydraulic power in hypertensive pigs.
Published 2025-01-01“…The hearts harvested at sacrifice were examined for myocardial hypertrophy, fibrosis, and dysfunction. The parameters capable of indicating high-workload heart and their prediction effectiveness were determined by cluster and receiver operating characteristic (ROC) analyses. …”
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5707
Consensus on Complement Inhibitor Therapy and Management of Paroxysmal Nocturnal Hemoglobinuria
Published 2025-01-01“…However, with the advent of complement inhibitors targeting complement components, which can block the complement cascade pathway and effectively control hemolysis and related symptoms, these drugs have emerged as the first-line therapy for hemolytic PNH. …”
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5708
COVID-19 vaccination and long COVID-19
Published 2025-03-01“…According to the literature, COVID-19 vaccines reduce long COVID-19 symptoms such as cognitive dysfunction, kidney diseases, myalgia, and sleeping disorders (5-7). …”
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5709
Postoperative Respiratory Depression Associated with Pregabalin: A Case Series and a Preoperative Decision Algorithm
Published 2011-01-01“…The first patient was elderly with borderline renal dysfunction. She experienced respiratory arrest in the immediate postoperative period following a craniotomy for tumour excision. …”
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5710
Determining influences of intraoperative s-ketamine on postoperative delirium and cognitive function: methodology is important
Published 2024-12-01“…This article concludes that intravenous low-dose S-ketamine during thoracic surgery in older patients significantly reduces the incidences of postoperative delirium and cognitive dysfunction, indicating a potential neuroprotective effect of intraoperative low-dose S-ketamine. …”
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5711
A Novel Assessment Reveals Motor Variability as a Sensitive Marker of Neurological Development, Decline, and Plasticity
Published 2025-01-01“…Our automated assessment potentially offers a scalable tool for early detection of motor dysfunction and quantification of motor training during physical rehabilitation.…”
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5712
Propofol Induces Postoperative Depression and Inhibits Microglial Function in Mice
Published 2019-01-01“…Postoperative depression may be resulted from cognitive dysfunction, pain, and a compromised immune system during the surgery. …”
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5713
Naringenin induces ferroptosis in osteosarcoma cells through the STAT3-MGST2 signaling pathway
Published 2025-02-01“…Ferroptosis is a novel form of regulated cell death induced by excessive iron accumulation, leading to lipid peroxidation that results in cellular dysfunction and death. Naringenin is a flavonoid known for its anti-cancer properties, yet its role in osteosarcoma has not been thoroughly studied. …”
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5714
Future prospects for the advancement of treatment of men with NOA: focus on gene editing, artificial sperm, stem cells, and use of imaging
Published 2025-05-01“…Gene editing technologies, particularly clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) protein 9 (CRISPR/Cas9), hold potential for correcting genetic mutations underlying testicular dysfunction. However, these technologies face challenges due to their complexity, potential off-target effects, ethical concerns, and affordability. …”
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5715
Craniofacial Pain: Brainstem Mechanisms
Published 1996-01-01“…Such peripherally induced modulation of brainstem nociceptive neuronal properties reflects the functional plasticity of the central V system, and may be involved in the development of headache and other conditions that manifest craniofacial pain and neuromuscular dysfunction.…”
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5716
Melatonin in Glaucoma: Integrative Mechanisms of Intraocular Pressure Control and Neuroprotection
Published 2025-05-01“…Included articles discussed its effects on IOP regulation, RGC survival, oxidative stress, mitochondrial integrity, and inflammation. …”
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5717
Attenuation of primate aging via systemic infusion of senescence-resistant mesenchymal progenitor cells
Published 2025-06-01“…Mesenchymal progenitor cells (MPCs), which play a central role in tissue repair, are particularly vulnerable to age-associated dysfunction. Lei et al. (Cell 188:1-22, 2025) address this limitation by engineering human embryonic stem cell-derived MPCs with enhanced FOXO3 activity (termed SRCs). …”
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5718
Coxsackievirus-induced miR-21 disrupts cardiomyocyte interactions via the downregulation of intercalated disk components.
Published 2014-04-01“…Deficiency in ICD components such as desmosomes, fascia adherens and gap junctions leads to heart dysfunction. Coxsackievirus B3 (CVB3) infection induces cardiac failure but its pathogenic effect on ICDs is unclear. …”
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5719
Targeting CREBRF in Cancer: Mechanistic Insights and Future Directions
Published 2025-05-01“…Depending on the tumor type and microenvironment, CREBRF exerts diverse effects by modulating distinct signaling pathways. …”
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5720
Approach of Chronic Pelvic Pain with Top Flat Magnetic Stimulation
Published 2023-01-01“…Pelvic floor tension myalgia (PFTM) represents a pelvic floor dysfunction related to increased activity or hypertonicity of pelvic floor muscles that leads to chronic pelvic pain or miofascial syndrome. …”
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