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  1. 5421

    Advance in the Correlation between Diabetic Nephropathy and Abnormal Serum Thyroid Hormone Levels in Patients by Zhiqiu Liu

    Published 2023-01-01
    “…TH has a potential renal protective effect and can also regulate glucose metabolism and improve abnormal glucose tolerance and insulin resistance. …”
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    Article
  2. 5422

    Mixed attention ensemble for esophageal motility disorders classification. by Xiaofang Wu, Cunhan Guo, Junwu Lin, Zhenheng Lin, Qun Chen

    Published 2025-01-01
    “…Esophageal motility disorders result from dysfunction of the lower esophageal sphincter and abnormalities in esophageal peristalsis, often presenting symptoms such as dysphagia, chest pain, or heartburn. …”
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    Article
  3. 5423

    Polycystic ovary syndrome: Criteria, phenotypes, race and ethnicity by Tsuyoshi Baba

    Published 2025-01-01
    “…Abstract Background Polycystic ovary syndrome (PCOS) is a complex endocrinopathy, which leads to ovulation dysfunction and infertility, as well as metabolic and mental disorders. …”
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    Article
  4. 5424

    The Role of Stress Regulation on Neural Plasticity in Pain Chronification by Xiaoyun Li, Li Hu

    Published 2016-01-01
    “…Increasing clinical studies and complementary animal models have elucidated effects of stress regulation on the pain chronification via investigating activations of the hypothalamic-pituitary-adrenal (HPA) axis and changes in some crucial brain regions, including the amygdala, prefrontal cortex, and hippocampus. …”
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    Article
  5. 5425

    Immune dysregulation as a driver of bronchiolitis obliterans by Kuimiao Deng, Gen Lu

    Published 2024-12-01
    “…This study emphasizes that immune dysfunction is an important driving factor in its pathophysiology. …”
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    Article
  6. 5426

    A Rare Case of a Good Neurological Outcome following Traumatic Foix-Chavany-Marie Syndrome by Katalin Arki, Christian Degen, Philipp Gruber, Luca Cioccari

    Published 2024-01-01
    “…Traumatic brain injury (TBI) can have profound acute and chronic effects, leading to permanent disabilities and diminished quality of life. …”
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    Article
  7. 5427

    Non-Coding RNAs in the Regulation of Doxorubicin-Induced Cardiotoxicity by Mengyao Sun, Il-Man Kim, Lei Yang

    Published 2025-05-01
    “…Notably, ncRNAs, including microRNAs, long non-coding RNAs, and circular RNAs, display critical functions in various DIC-associated cellular processes, such as cell death, oxidative stress, and mitochondrial dysfunction, all of which contribute to the pathophysiology of DIC. …”
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    Article
  8. 5428

    PF4 regulates neuronal ferroptosis in cerebral hemorrhage through CXCR3/PI3K/AKT/Nrf2 pathway by Na Hu, Yunfeng Li, Guohong Zhang, Wei Wang, Liping An, Ran An, Yu Liu

    Published 2024-11-01
    “…Hemin-treated PC12 cells were co-cultured with recombinant mouse PF4 (Rm-PF4) protein to examine the effects of PF4 on ferroptosis. Additionally, Rm-PF4 was administered intraperitoneally to ICH mice, and its influence on neurological dysfunction, brain edema, and neuronal ferroptosis was evaluated. …”
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    Article
  9. 5429

    Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial by Queralt Asla, Maite Garrido, Eulàlia Urgell, Sílvia Terzan, Alicia Santos, Mercè Fernández, Nimmy Varghese, Cihan Atila, Anna Calabrese, Betina Biagetti, Franziska Plessow, Ignasi Gich, Mirjam Christ-Crain, Anne Eckert, Susan M. Webb, Elizabeth A. Lawson, Anna Aulinas

    Published 2025-01-01
    “…Abstract Increasing evidence supports the presence of oxytocin deficiency (OXT-D) in patients with hypopituitarism and hypothalamic damage (HHD), that might be associated with neuropsychological deficits and sexual dysfunction, leading to worse quality of life (QoL). …”
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    Article
  10. 5430

    Rethinking Short-Chain Fatty Acids: A Closer Look at Propionate in Inflammation, Metabolism, and Mucosal Homeostasis by Sonia Facchin, Matteo Calgaro, Edoardo V. Savarino

    Published 2025-07-01
    “…However, excessive accumulation is linked to neurotoxicity, autism spectrum disorder (ASD), and mitochondrial dysfunction. Its effects are dose-dependent and tissue-specific, with both protective and harmful potentials depending on the context. …”
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    Article
  11. 5431

    L-asparaginase: New about Well-Known Drug by Yuliya S. Korkina, Timur T. Valiev

    Published 2021-07-01
    “…With time ideas about the asparaginase mechanisms have expanded, new data have been accumulated on adverse effects (allergic reactions, thrombotic complications, pancreatitis, hepatic dysfunction, etc.). …”
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  12. 5432

    Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients by Monika Kniotek, Agnieszka Boguska

    Published 2017-01-01
    “…This is the first review of the current state of knowledge about the effects of sildenafil on the immune system.…”
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    Article
  13. 5433

    Revisiting anesthesia-induced preconditioning for neuroprotection in the aging brain: a narrative review by Tao Zhang, Woosuk Chung, Beverley A. Orser

    Published 2025-06-01
    “…The discordance between preclinical and clinical outcomes may be due to age-related mitochondrial dysfunction and other comorbidities in older human populations, which reduce the effectiveness of anesthetic preconditioning. …”
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    Article
  14. 5434

    Sodium Glucose Transporter 2 Inhibitor Protects Against Heart Failure With Preserved Ejection Fraction: Preclinical “2‐Hit” Model Reveals Autophagy Enhancement Via AMP‐Activated Pr... by Xinyu Hu, Dan Li, Weijie Chen, Hongyu Kuang, Dan Yang, Zhiyan Gong, Yuxiang Long, Guangliang Liu, Kai Wang, Mengshi Xia, Yanping Xu, Yuehui Yin

    Published 2025-08-01
    “…Conclusions Empagliflozin effectively ameliorates cardiac remodeling and diastolic dysfunction in HFpEF by enhancing autophagy via the AMPK/mTORC1 pathway. …”
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    Article
  15. 5435

    The impact of collaborative pain management by healthcare providers on sleep quality and self-efficacy in perioperative lumbar surgery patients by Jucai Li, Yanli Song, Yixin Zhao, Dan Su, Meina Li, Shu’e Zhao

    Published 2025-02-01
    “…Abstract The present study aimed to investigate the effects of collaborative pain management by healthcare providers on sleep quality and self-efficacy in perioperative lumbar disc herniation patients. …”
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  16. 5436

    Remnant cholesterol, preinflammatory state and chronic kidney disease: association and mediation analyses by Yougen Yuan, Xiangming Hu, Shanghong Zhang, Weimian Wang, Bingyan Yu, Yingling Zhou, Yanqiu Ou, Haojian Dong

    Published 2024-12-01
    “…These findings highlight the importance of RC and inflammation in renal dysfunction. IMPACT STATEMENTWhat is already known on this subject?…”
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  17. 5437

    The Role of Leu-Enkephalin Synthetic Analogue in Regulation of Systemic Inflammatory Response and Prevention of ARDS in Severe Combined Injury by A. Y. Ryzhkov, V. V. Antonova, R. A. Cherpakov, E. A. Chernevskaya, A. K. Shabanov, D. A. Ostapchenko, M. A. Magomedov, O. A. Grebenchikov

    Published 2024-04-01
    “…The aim of the study. To study the effect of ley-enkephalin synthetic analogue on the dynamics of inflammatory response markers and organ dysfunction in patients with severe combined trauma.Materials and methods. …”
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    Article
  18. 5438
  19. 5439

    Vaccination in Patients with Chronic Lymphocytic Leukemia: Current Problems by M. I. Kislova, A. A. Petrenko, M. P. Kostinov, E. A. Nikitin

    Published 2021-07-01
    “…Additional clinical trials are needed to improve the effectiveness of vaccination in patients with CLL.…”
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  20. 5440

    ACE INHIBITOR ZOFENOPRIL IN COMPLEX THERAPY OF CHRONIC HEART FAILURE AND DILATED CARDIOMYOPATHY by Z. T. Astakhova, D. S. Zagalova

    Published 2010-04-01
    “…The study assessed the effectiveness of an ACE inhibitor zofenopril in the treatment of patients with dilated cardiomyopathy (DCMP), complicated by chronic heart failure (CHF). …”
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